여성의 골밀도에 영향을 미치는 요인 분석

등정영작,유병욱,조용진,오정은,홍성호,조주연 순천향대학교 순천향의학연구소 2008 Journal of Soonchunhyang Medical Science Vol.14 No.1

Background: The mechanism of bone mineral density decrease related to aging is not completely known yet. Although the bone mineral density has correlations with weight, height and body fat volume, there was no research in relation to muscles and fat volume of limbs. Currently obesity is known as the preventative factor for osteoporosis; however, it is true that many difficulties are entailed in the prevention of osteoporosis by simply gaining weight. This study has been conducted to see the relations between the circumference of limbs and bone mineral density. Methods: The study target was 30 women, who were not applied to exclusion criteria among 50 women who visited an university hospital in Cheonan to get a physical check up from October 2003 to March 2004. The survey was conducted by questionnaire, doctor's diagnosis by asking questions and physical check up. In this manner, any factors known to have some bearings on bone mineral density have been researched. In terms of the relation with each variable, Pearson correlation was identified through SPSS 10.0k/PC statistical program, and multiple linear regression analysis was carried out. The living factors which can impact upon bone mineral density were tested by t-test and simple linear regression analysis. Results: The target was thirty women. As a results of checking the Pearson correlation, after controlling for age was made in terms of correlation between bone mineral density of lumbar spine and thigh and other factors, only lumbar bone density showed that significant correlation was indicated in weight, body fat index, brachium circumference, body fat volume, various fats volume, muscle volume, body water volume, protein volume and mineral volume (P<0.05). As a results of checking the t-test of living factors, menopause influenced overall lumbar and thigh bone mineral density (P<0.01). Smoking indicated insignificant correlation in the entire bone density. Drinking alcohol showed a significant correlation in lowering bone mineral density of trochanter (P=0.026) and shaft (P=0.012). Exercise showed no significant correlation in raising the entire bone mineral density. As a results of checking the simple linear regression analysis between drinking alcohol and bone mineral density of trochanter and shaft, there is no correlation. Conclusion: Lumbar bone mineral density has some relations with weight, body mass index, brachium circumference, body fat volume, various fats volume, muscle volume, body water volume, protein volume and mineral volume. Living factors was known to have no relations with bone mineral density.

체성분이 폐경 전후 여성의 골밀도에 미치는 여향

배성욱,남철현,신두만,차경미,서인선 慶山大學校 保健福祉硏究所 2002 保健福祉硏究 Vol.7 No.-

Objectives : To evaluate the degree of bone mineral density and prevalence rate of osteoporosis according to age and to search the preventive strategy for osteoporosis, the factors that affect on bone density were studied in Physical Characteristics of pre- and postmenopausal women in korea. Methods : The subjects were 961 premenopausal and 1,167 postmenopausal women who have examined in health promotion center of Yeungnam University Hospital in Daegu city from January, 1999 to January, 2001. The test for bone mineral density, biochemical factors, and body composition were done. Results : 1) The prevalence rates of reduced bone mineral density and osteoporosis in premenopausal women were 23.8% and 1.6%, respectively. However, these values were increased to 46.1% and 28.1% in postmenopausal women. 2) The body weight and height were important predictive factors for bone mineral density. The effects of age, body weight, and height on bone mineral density were 39%. The body weight was correlated statistically significantly with bone mineral density in pre- and postmenopausal women. The higher body mass index (BMI), the greater value of bone mineral density was revealed in pre- and postmenopausal women. 3) The correlation between body composition adjusted for body weight and bone mineral density revealed similar pattern between pre- and postmenopausal women. The height, lean body mass, muscle mass, mineral content, and mineral fraction were positively correlated with bone mineral density, however, body fat mass, percent body fat, waist/hip ratio, and BMI were correlated negatively with bone mineral density. 4) There was no direct correlation between cardiovascular risk factor and bone mineral density in this study, however, further study is needed because cardiovascular disease and osteoporosis have common risk factor and the prevention of osteoporosis can help to prevent cardiovascular disease. 5) In multiple regression analysis among bone mineral density as a dependent variable and independent variables (age, body weight, height, Ca/creatinine ratio, and alkaline phosphatase (ALP)), ALP revealed statistically significant inverse correlation with bone mineral density. Conclusions : These results suggested that to prevent osteoporosis, the systemized program including physical condition for promoting anti-osteoporotic factor have to be developed and apply from the thirties whom have maximal bone mineral density.

폐경 전후 여성의 신체특성 및 산과력과 골 밀도간의 관련성

남철현 ( Chul-hyun Nam ),배성욱 ( Seong-wook Bae ),김복용 ( Bok-yong Kim ) 한국모자보건학회 2002 한국모자보건학회지 Vol.6 No.2

Objectives : This study was conducted to evaluate the prevalence rate of osteoporosis according to age and the effect of physical characteristics and obstetrical history on bone mineral density in pre- and postmenopausal women in Korea. Methods : The subjects were 961 premenopausal and 1.167 postmenopausal women who had been examined in health promotion center of Yeungnam University Hospital in Daegu city from January, 1999 to January, 2001. The test for bone mineral density, and body composition were conducted. Results : The results of this study were as follows; 1. The prevalence rates of reduced bone mineral density and osteoporosis in premenopausal women were 23.8% and 1.6%, respectively. However, these values were increased to 46.1% and 28.1% in postmenopausal women. 2. The age was most important predictive factor for bone mineral density in pre- and postmenopausal women. The bone mineral density was peaked at the thirties and declined sharply around fifty years old and declined slightly after the seventies, which revealed a typical cubic equation. The loss of bone mineral density was started at forty years old. 3. The body weight and height were important predictive factors for bone mineral density. The effects of age, body weight, and height on bone mineral density were 39%. The body weight was correlated statistically significantly with bone mineral density in pre- and postmenopausal women. The higher body mass index (BMI), the greater value of bone mineral density was revealed in pre- and postmenopausal women. 4. In multiple regression analysis, age, body weight, height showed statistically significant inverse correlation with bone mineral density. Conclusions : These results suggested that to prevent osteoporosis, the systemized program including physical condition for promoting anti-osteoporotic factor have to be developed and apply from the thirties whom have maximal bone mineral density.

무용 전공여학생의 연령대별 대퇴골 근위부 골밀도에 관한 연구

오덕자(Deuk Ja Oh),박병주(Byung Ju Park) 한국사회체육학회 2004 한국사회체육학회지 Vol.0 No.21

To study how dance effects on the femur of the majoring dance girls, the bone mineral density is measured and analysed by using DEXA according to groups and age. The subjects are 85 general middle, high school and college girls(A group), 82 majoring Korean dance in art middle, high school and college girls(B), 86 majoring ballet(C), 50 majoring modern dance(D), they are living in B metropolitan city. The results are as follows : Femoral Neck(RFN·LFN) with age, at the age 13-15, ballet and Korean dance groups` bone mineral density of RFN·LFN is higher meaningfully than general group. In the age 16-18, modem dance group`s RFN bone density is higher meaningfully than Korean dance and general group. Modern dance, ballet and Korean dance groups` LFN bone density is higher than general group. In the age 19-21, modem dance group`s RFN·LFN bone mineal density is higher meaningfully than Korean dance and general groups. In the Trochanter(RTH·LTH) with age, at the 13-15 ages, the ballet and Korean dance groups` RTH·LTH bone mineral density is higher meaningfully than general group. In the age 16-18, modern dance, ballet, Korean dance groups` RTH bone mineral density is higher meaningfully than general group. Modem dance group`s LTH is higher meaningfully than Korean dance and general group. In the age 19-21, modern dance group`s RTH bone mineral density is higher meaningfully than Korean dance and general group. Modem dance group`s LTH bone mineral density is meaningfully higher than ballet and general group. In the Ward`s triangle(RWT·LWT) with age, at 13-15 ages, ballet and Korean dance groups` RWT·LWT bone mineral density is higher meaningfully than the general group. In the age 16-18, modern dance group`s RWT·LWT is higher meaningfully than general group. In the age 19-21, RWT·LWT has no difference among groups. Conclusionally, as the proceeding study has a little difference, there is difference according to parts. However, the bone mineral density of 3 majoring dance groups` femur is higher and peak bone density appearance age is somewhat faster. Accordingly, regular dance activity can help the increase of peak bone density and the earliness of peak bone density. So dance activity can effect on the positive change of bone mineral density.

폐경기 여성의 운동형태가 골밀도에 미치는 영향

김은경,이계영,이삼준,심영제 한국스포츠리서치 2004 한국 스포츠 리서치 Vol.15 No.6

The relationship of bone mineral density and type of physical exercise was studied in 36 Postmenoposal Women(age 48-57). The exercise group consisted of Weight training([ =9), Aerobic dance(N=8), Swimming(N=9) and the control group consisted of 10 women. Bone mineral density was measured Lumber(L2-L4), Femur neck, Ward's triangle bone density. The results statstically analyzed on these data were summarized as follows: first, Lumber (L2-L4) bone density, Femoral neck bone density, Ward's triangle bone density in Weight training group was significantly higher than in Swimming group and Control group. Secondly, Lumber(L2-L4) bone density, Femoral neck bone density, Ward's triangle bone density in Aerobic dance group was significantly higher than in Swimming group and control group. Thirdly, No significant difference were round for Lumber(L2-L4) bone density, Femoral neck bone density in Weight training group and Aerobic dance group.

The Effect of Aerobic Dance on Bone Density in Climacteric Women

Park, Kye-Soon 한국체육무용국제교류학회 1999 한국체육무용국제교류학회지 Vol.5 No.-

The purpose of this study was to investigate the effects of aerobic dance on bone density in climacteric women. Climacteric women aged 40 to 55 years were enrolled to this study. They were divided into aerobic dance group(N=8)and control group(N=8), experienced for 16 weeks. Aerobic dance group has the intensity from 40% to 85% of maximal heart rate. Aerobic dance group increased the ward triangle, lumbar 2-4 and osteocalcin but decreased femur trochant, femur neck. Control group increased the femur trochant, femur neck and ward trianagle but decreased lumbar 2-4, osteocalcin. Aerobic dance treatment of 16weeks tended to increase bone density of climacteric women but was of no effect of increasing of bone density, because aerobic dance treatment which consisted of articulation exercise was not proper for mechanics stress of weight. Then, for density aerobic dance with muscles exercise which weight down to the body than this do less density aerobic dance with muscles exercise which weight down to the body than this aerobic dance, and, differently to the exercise effect of another part of body, The effect of aerobic dance for bone density is expected to do the longer aerobic dance. It is important structure that our bone prop our body. Then the integrety of bone density diminished its own density after one's age of 30s even people two. When bone density diminished if a woman who had menopause have dropped her bone density. It would be lack of woman's known as estrogen(16,17). It is determined to gage human's bone density that different from young woman and old woman bone structure(4). Generally speaking the woman is more likly to have a osteoporoses than the man, 70~80% of elapsed the age of 50s human have a osteoporoses all we are concerned with osteoporoses high(6). It can be a osteoporoses to a woman of 3~5% at first time her menstruation period. It is diminished woman's bone density after ten years from her first menstruation . One third of woman had a defficiency of bone density because most woman less have a mount of bone than most man have affect of hormon, less activated movement less production of estrogen be operated by ovary erased treatment etc(14). As terminated the dangerous thing in the individuality and environment, it can diminish woman's of osteoporoses. It can be recovery the woman's bone density through the treatment of low calcium but it can't be recovery its heredity. So one must manage their health statement continually(10). O'connell(1996) said that the only thing which treat a lack of bone is a aerobic dance especially. Nkansah(1993) said that the main causual osteoporosis is enviromental and hereditical one enviromental cause of osteoporoses is lack of eating calcium or regular dance(1,2,3,5,9,11,12,13,15,18).

장기간 태권도 수련이 여대생의 골밀도 및 골밀도 관련 호르몬에 미치는 효과

김연수 ( Yeon Soo Kim ),전태원 ( Tae Won Jun ),박성태 ( Sung Tae Park ),강현주 ( Hyeon Joo Kang ),정진욱 ( Jin Wook Chung ),서형관 ( Hyung Gwan Seo ) 한국스포츠정책과학원(구 한국스포츠개발원) 2003 체육과학연구 Vol.14 No.1

본 연구의 목적은 장기간의 태권도 수련이 20대 여성의 골밀도 및 골밀도 관련 호르몬에 미치는 영향을 규명하는 데 있다. 이를 위하여 장기간동안 태권도를 수련한 여대생 태권도 선수 9명과 일반여대생 9명을 대상으로 골밀도 및 관련 호르몬을 검사하였다. 두 그룹간 변인들의 측정치를 독립 t 검정으로 분석한 결과, 요추골밀도는 태권도그룹에서 1.253±0.031g/cm2, 일반그룹에서 1.144±0.029g/cm2(p<.05), 대퇴골밀도는 태권도그룹에서 1.189±0.076g/cm2, 일반그룹에서 0.931±0.091g/cm2(p<.01)로 유의한 차이를 나타냈으나, 요골골밀도는 태권도그룹에서 0.379±0.011g/cm2, 일반그룹에서 0.348±0.009g/cm2로 유의한 차이를 나타내지 않았다. 호르몬 중 에스트로겐은 태권도그룹에서 826.00±228.29pg/ml, 일반그룹에서 535.11±252.33pg/ml(p<.05), 오스테오칼신은 태권도그룹에서 31.26±16.87ng/ml, 일반그룹에서 10.62±2.30ng/ml(p<.01)로 나타나 통계적으로 유의한 차이를 나타냈으나, 부갑상선 호르몬은 태권도그룹에서 41.74±16.98pg/ml, 일반그룹에서 30.75±1.99pg/ml, 칼시토닌은 태권도그룹에서 30.23±4.73pg/ml, 일반그룹에서 23.78±3.78pg/ml로 나타나 통계적으로 유의한 차이를 나타내지 않았다. 태권도그룹의 골밀도와 골밀도 관련 호르몬과의 상관관계는 요추골밀도와 오스테오칼신(p<.05), 요골골밀도와 오스테오칼신(p<.05), 대퇴골밀도와 에스트로겐(p<.05)에서 상관관계가 있는 것으로 나타났으며, 일반그룹에서는 대퇴골밀도와 에스트로겐(p<.05), 요추골밀도와 칼시토닌(p<.05)에서 상관관계가 있는 것으로 나타났다. 결론적으로 태권도를 장기간 수련한 태권도그룹이 일반그룹보다 골밀도 및 골밀도 관련 호르몬 농도가 높게 나타남으로써, 태권도가 골밀도 증가 및 골다공증 예방운동으로서의 특성을 충분히 가지고 있는 것으로 사료된다. As you can see above, Taekwondo, which is not only Korea`s national skill but also a worldwide cultural heritage, can contribute to stronger bone. For that reason, providing scholarly research as evidence of the effect of practicing Taekwondo is needed. This research will contribute to encourage greater participation in Taekwondo which could lead to prevention and decline of the occurrence of osteoporosis. The correlation between the presence of female hormone and bone mineral density has been well established in this research. The experimental group included nine female Taekwondo players and the control group consisted of nine women of the same age, social status and attending the same University but did not participate in Taekwondo. The experimental group`s bone mineral density is higher than the control group`s, especially noticeable in the lumbar spine and femur bones. There`s no statistical difference in radius bone between the two groups, but bone mineral density is slightly higher in the experimental group. A hormone concentration level from the experimental group is higher than the control group`s and there is a significant trend of differences from estrogen(p<0.05), osteocalcin(p<0.01). In the experimental group, there appeared correlationship highly between osteocalcin and lumbar spine bone mineral density, between radius bone mineral density and osteocalcin, and between femur bone mineral density and estrogen. In the control group, there appeared correlationship highly between femur bone mineral density and estrogen and between lumbar spine bone mineral density and calcitonin. According to this data, practicing Taekwondo is positively correlated with improved bone density. Therefore, practicing Taekwondo can result in bone density. This research also indicates that practicing Taekwondo can contribute to the prevention of osteoporosis. At this writing, this research is inclusive regarding the effects of Taekwondo on hormones, and further research needed to determine whether parathyroid hormone may contribute to making bones which aids in preserving bone mineral density or not. However, conclusive evidence exists to establish that maximizing bone mineral density prevent osteoporosis.

50세 이상 한국 여성의 연령, 체중, 신장에 따른 골밀도의 비교 연구

나수균,윤승렬,추성옥 순천향의학연구소 2000 Journal of Soonchunhyang Medical Science Vol.6 No.2

We evaluate the bone mineral density of lumbar spine, femur neck, femur trochanter, Ward's triangle, and distal radius of orthopaedic women patient over 50 years old who wanted to evaluate BMD, or who had soft tissue disease and trauma history such as tendon, ligament and skin injury(583 cases) to compair with normal korean women BMD, by using dual energy X-ray absorptiometry(DEXA) Results obtained were as follows : 1) The average incidence of the osteopenia is 22%, and of the osteoporosis is 71%. 2) The changes of the bone mineral density according to age demonstrate linear decrease in spine and hip, but shows cubic form in distal radius. 2) The changes of the bone mineral density according to height demonstrate linear increase in spine, hip, and distal radius regardless of age, but according to height of same age group, the correlation of bone mineral density of spine and height is only statistically significant. 3) The changes of the bone mineral density according to body weight demonstrate linear increase irrespective of the difference between sponge bone and compact bone. 4) There is statistically significant correlation of menopausal age and bone mineral density irrespective of the difference sponge bone and compact bone. 5) There is no statistically significant correlation of menarche and bone mineral density. In conclusion, we should have more considerations of the bone mineral densities whose statures are short, and of the bone mineral densities of the patients of the department of orthcpaedics

정량적 컴퓨터 단층촬영을 이용한 골밀도 검사에 있어 정확한 측정위치에 관한 연구

김성은(Seong Eun Kim),이혜진(Hye Jin Lee),임기빈(Ki Bin Lim),강성호(Sung Ho Kang),임재식(Jae Sik Lim) 대한전산화단층기술학회 2013 대한CT영상기술학회지 Vol.15 No.1

목적 : 본 연구는 QCT를 이용한 골밀도 검사에 있어 흉추와 요추부위의 ROI 위치변화와 대퇴경부의 측정각도에 따른 골밀도 값의 변화를 비교 분석하여 정확한 측정을 위한 기준점을 알아보고자 한다. 대상 및 방법 : 2012년 11월1일부터 2013년 1월31일까지 본원을 내원하여 QCT 검사를 시행한 환자 중 측정의 신뢰도를 높이기 위해 골밀도 측정 부위에 골절이 없는 환자 남자 2명, 여자 53명을 대상으로 하였다. 연구에 사용된 CT장비는 GE사의 LightSpeed VCT 64를 사용하였으며, 획득한 자료는 QCT PROTM (Mindway, GE, Madison, WI, USA) 프로그램을 사용하여 T-12(thoratic spine 12), L-1(lumbar spine 1), L-2(lumbar spine 2)와 대퇴경부의 BMD(bone mineral density)(mg/cm³), Z-score와 T-score를 측정하였다. 대조군의 경우 QCT 프로그램에서 권고하고 있는 기본적인 수정원칙을 지켜 측정을 시행하였으며 실험군의 경우 대조군와 동일한 수정조건을 유지한 후 최종단계에서 흉추와 요추의 경우 ROI의 위치를 venus complex defect가 포함되지 않도록 중앙으로 이동시켜 골밀도 값을 측정 하였고, 대퇴경부의 경우 측정각도를 위로 5도와 10도, 아래로 5도와 10도 변화시켜 연구를 진행하였다. 골밀도 측정 위치가 변함에 따라 측정값이 변할 것이라는 연구가설과 실험연구를 통해 확인된 가설에 신뢰성을 부여하기 위해 실시하였다. 연구대상 55명 중 20명을 무작위로 선택한 후 5명의 방사선사가 독립적으로 골밀도 값을 측정한 후 각 그룹에서 유의한 차이가 발생하는지 알아보았다. 결과 : 흉추와 요추의 대조군과 실험군의 골밀도 측정결과 BMD의 경우 ROI 위치를 중앙으로 이동하여 측정한 실험군의 T-12, L-1 과 L-2 의 BMD 값은 147.8, 137.5, 152.9 mg/cm³으로 대조군에 비해 8.5%, 4.7%, 17.7% 높았으며, Z-score와 T-score 경우 64.6% 와 26.3% 높게 측정되었다. ROI 위치 변화에 따른 상관관계를 알아보기 위한 유의성 검정결과 그룹 간 흉추와 요추의 BMD 값 모두 유의한 차이를 보였다. Z-score와 T-score값 역시 유의한 차이를 보였다. 대퇴경부의 경우 대조군과 각도를 변경하여 측정한 실험군의 측정결과 다른 부위와 비교하여 대퇴경부의 BMD, T-score와 Z-score에서 최대값과 최소값의 차이가 크게 나타났으며 통계적으로도 유의한 차이(p〈0.05)를 보였다. 5명의 방사선사가 독립적으로 측정한 임상연구 결과 5명 모두 BMD에서 평균값의 차이를 보였으며 최대값과 최소값의 차이는 T-12(thoracic spine 12)의 경우 10.7, L-1(lumbar spine 1)에서 5.7, L-2(lumbar spine 2)에서 12.6의 차이를 보였다. Score의 최대값과 최소값의 차이는 Z-score 0.156, T-score 0.271의 차이를 보였고 세 개의 그룹에서 유의한 차이(p〈0.05)를 보였다, 대퇴경부의 BMD, Z-score와 T-score의 최대값과 최소값의 차이는 0.158, 0.7, 0.0068 이었고 두 개의 그룹에서 유의한 차이(p〈0.05)를 보였다. 결론 : 연구결과 골밀도를 결정하는 T-score와 Z-score의 값이 측정방법의 변화에 따라 유의한 차이를 보였으며 이러한 결과는 추적 검사 시 측정자의 측정방법에 따라 결과치가 상당부분 달라질 수 있음을 시사하고 있다. 따라서 QCT를 이용한 골밀도 측정은 측정자의 주관적인 판단에 따라 ROI의 위치나 각도를 변경하지 않는것이 중요하며, 특히 추적검사의 경우 기존에 흉추와 요추에서 측정했던 ROI 위치와 대퇴경부의 측정각도를 확인한 후 동일한 조건에서 측정을 하는 것이 신뢰성을 담보할 수 있는 방법일 것이다. Purpose : In terms of the bone density examination by QCT, the study would compare the bone density value is changed based on ROI location at the thoracic vertebrae as well as the lumbar vertebrae and measurement angle at the femoral neck. With any results found from the comparison, the study shall come up with a reference point that wⅢ realize the accurate measurement of the bone density. Object and Research Method : The study has carried out onto a patients group that consisted of 2 males and 53 females who received QCT check in the concerned hospital between November 1, 2012 and January 31, 2013. The study has selected patients who have never been diagnosed with a bone fracture at a part to be measured for the bone density in order to improve reliability of the measurement. Regarding CT equipment used in the study, LightSpeed VCT 64 by GE was adopted while acquired data was analyzed by QCT PROTM(Mindway, GE, Madison, WI, USA) program to measure BMD(bone mineral density)(mg/cm³), Z-score and T-score of (thoratic spine 12), L-1(lumbar spine 1), L-2(lumbar spine 2) and the femoral neck. For a control group, the measurement was operated based on the fundamental correcting criterion recommended by QCT program. For an experimental group, the correcting criterion should be identical with that of the control group but stⅢ, at the final stage, ROI location of the thoracic vertebrae and the lumbar vertebrae wⅢ not include venus complex defect. For that purpose, ROI has been moved to the center before the bone density was measured, and again, in case of the femoral neck, the study was conducted as the measurement angles were revised by 5˚ and 10˚ upwards as well as 5˚and 10˚ downwards. Such experiments were carried out to pursue reliability of the confirmed hypothesis which says that a different bone density measurement location wⅢ affect measurement values. Out of the 55 research objects, 20 were randomly selected to be separately measured for the bone density by five radiological technologists. Afterwards, any significant differences were searched in each of the groups. Results : When it comes to comparing the bone density of the thoracic vertebrae and the lumbar vertebrae from the control group and the experimental group, in case of BMD with ROI moved to the center, the experimental group was appeared to have BMD value of 147.8, 137.5 and 152.9 mg/cm³ for T-12, L-1 and L-2. The findings were proved to be higher by 8.5%, 4.7% and 17.7% than those of the control group. In terms of Z-score and T-score, the experimental group, again, came up with greater values by 64.6% and 26.3%. A significance test was carried out to study a correlation depending on different ROI location. According to the results, all BMD values of the thoracic vertebrae and the lumbar vertebrae between the groups were found to have a significant difference. That went the same both with Z-score and T-score values as they came out with another significant value. In case of the femoral neck, different angles were adopted for the experimental group. The results were compared to those values from the other parts, and BMD, T-score and Z-score of the femoral neck appeared to have a great difference with the maximum value and the minimum value. That was proved to be statistically significant with a value of p〈0.05. Five radiological technologists separately performed a clinical research on the selected patients. According to the results, all the five objects came up with a different average value with BMD, and for the gap between the maximum value and the minimum value, T-12 showed 10.7 while L-1 and L-2 ended up with 5.7 and 12.6 respectively. As to the difference of Score with the maximum value and the minimum value, Z-score provided 0.156 while T-score showed 0.271. The three groups were confirmed to have a significant difference (p〈0.05). The difference between the maximum value and the minimum value of BMD, Z-score and T-score of the f

소아의 골밀도에 관한 연구

장규태,김장현,서영민,Chang, Gyu-Tae,Kim, Jang-Hyun,Seo, Young-Min 대한한방소아과학회 2005 대한한방소아과학회지 Vol.19 No.1

Objectives : Osteoporosis is generally occurred in old age, especially postmenopausal women therefore, it is relatively overlook osteoporosis in children, but the authors have paid attention to bone density in children because maximizing peak bone mass of childhood is advocated as a way to prevent osteoporosis and environmental factor of childhood play role in the regulation of bone density. the present study was performed to measure bone density of children and to assess the influence of age, sex, body size, exercise, weak symptoms on bone density during the period of bone growth. Methods : We have measured bone density of calcaneus bone in 283 children (male 144 female 139, ranged from3 to 18) who visited in growth clinic of Pediatrics, Dongguk University Bundang Oriental Hospital, using quantitative ultra sound densitometry and they were divided into 3 groups by age(3-10, 11-15, 15-18 years). Pearson's correlation was used to assessed the influence of age, body size and Student's t-test was used to detect differences in sex, exercise, weak symptoms between the groups on bone density Results : The bone density correlated with age, height, weight, body mass index in this study. Bone density were significantly higher in males than in female. Digestive weak children's bone density were lower than normal children. Conclusion : Weight-bearing exercise and food rich in nutrition are necessary to increase maximizing peak bone mass in children.