응급실에서 기관내 삽관후 발생한 후두육아종 1례

조남수,김용배,조수형,송민엽,송성용 大韓應急醫學會 1996 대한응급의학회지 Vol.7 No.1

Endotracheal intubation has been used widely for the maintenance of airway in the emergency patient and CPR in the acute airway obstruction patient and to treat respiratory insufficiency. Endotracheal intubation has many advantages but it may cause several complications which rate about 4% of endotracheal intubation patient. Among these complications, laryngeal granuloma is a relatively rare complication arising about 1 case per 10,000∼20,000 cases. Authors report a case of laryngeal granuloma which developed after endotracheal intubation required during emergency treatment. Case: A 55-year old female patient visited Chosun University Hospital Emergency Room complaining of dyspnea, cyanosis and sweating on Feb. 8th 1995. According to past history, she had a little obesity, dyspnea on exercise and mild hypertension. At arrival, blood pressure was 240/110mmHg, pulse rate 150 rates/min, respiratory rate 12/min, body temperature 36.5℃ and cyanosis with sweating on whole body was observed. And the mental state was semicoma. At 5 minutes after arrival, sudden respiratory arrest developed and immediate endotracheal intubation which emergency treatment was performed it was difficult to intubate endotracheally due to short neck and obesity. At 1 hour after arrival, general condition of the patient recovered well and extubation was done. The patient was transferred to internal medicine department and discharged after 12 days of medical treatment. At 2 months after discharge, the patient felt a progressive hoarseness and foreign body sensation of larynx. She was diagnosed as laryngeal granuloma at ENT department of Chosun University. She underwent the surgical operation and discharged in good health after 7 days of admission.

Genome-wide investigation of a Korean synthetic breed, Woori-Heukdon using the Illumina PorcineSNP60K BeadChip

Yong‑Min Kim,Ha‑Seung Seong,Jung‑Jae Lee,Da‑Hye Son,Jin‑Su Kim,Soo‑Jin Sa,Young‑Sin Kim,Tae‑Jeong Choi,Kyu‑Ho Cho,Joon‑Ki Hong,Jung‑Woo Choi,Eun‑Seok Cho 한국유전학회 2020 Genes & Genomics Vol.42 No.12

Background: Woori-Heukdon (KWH) is a Korean synthetic pig breed generated using Chookjin-Duroc (KCD), Chookjin-Chamdon (KCC), and their crossbreds. Currently, there is a severe lack of studies investigating the Korean breed populations including wild boars (KWB) throughout the genome. Objective: This study was performed to investigate the genetic characteristics of Korean pig populations at the genome-wide level. Methods: Using the SNP dataset derived from genotyped and downloaded datasets using the Illumina PorcineSNP60K BeadChip, we compared the genomes of 532 individuals derived from 23 pig breeds to assess the genetic diversity, inbreeding coefficient, genetic differentiation, and population structure. Results: KWB showed the lowest average expected heterozygosity (HE = 0.1904), while KWH showed the highest genetic diversity (HE = 0.02859) among Korean populations. We verified that the genetic composition of KWH, showing USD of 74.8% and KCC of 25.2% in ADMIXTURE analysis. In population structure analyses, KCC was consistently shown to be separated from other pig populations. In addition, we observed gene flow from Western pigs to a part of Chinese populations. Conclusion: This study showed that Korean native pigs, KCC have genetic differences in comparison with Chinese and Western pigs; despite some historical records and recent genetic studies, we could not find any clear evidence that KCC was significantly influenced by Chinese or Western breeds in this study. We also verified the theoretical genomic composition of KWH at the molecular level in structure analyses. To our knowledge, this is the first genomic study to investigate the genomic characteristics of KWH and KCC.

위암환자의 복강내에 투여한 Mitomycin C-Carbon Particle의 Mitomycin 용출에 관한 연구

노승무,조영훈,정경수,오정연,김진향,양준묵,강대영,송규상,조준식,최선웅,이진호,민병무,김용백,김창식,박근성,인현빈,정현용,김학용 충남대학교 의과대학 지역사회의학연구소 1998 충남의대잡지 Vol.25 No.1

Locoregional recurrence is the most common type of recurrence in surgical operation of gastric adenocarcinoma, and peritoneal dissemination is one of the most difficult problems in advanced gastric adenocarcinoma treatment. Because the peritoneal cavity is the most common site of the first recurrence after gastric cancer resection, intraperitoneal chemotherpy seems a logical choice for cancer chemotherapy. The Mitomycin C(MMC) adsorbed by the activated charcoal particles(CH) is relatively released when the drug concentration surrounding the carbon particles becomes low in the peritoneum of the peritoneal cavity. For the intraperitoneal chemotherapy on the advanced gastric adenocarcnoma, mitomycin C adsorbed on activated carbon particles was administered in the peritoneal cavity just before abdominal wall closure. The closed drainage tubes were inserted in the peritoneal cavity and clamped for tuo hours after completion of operation. MMC concentrations were serially measured in peritoneal fluid, plasma and urine at 2hour, 48 hour, 72 hour and 168 hour following its administration in order to study the efficacy of the MMC-CH as a drug delivery system. There were minimal toxicities in born marrow, liver, and gastrointestinal system after intraperitoneal MMC-CH administration. The data of this study suggested that MMC-CH may have a somewhat more beneficial effect than surgery alone when administered in optimal dose and schedules, but the MMC concentration of the peritoneal fluid was not sufficient to eradicate remnant cancer cells, and effective duration of maintenance was only below 24 hours in the peritoneal fluid and plasma.

용접공들의 면역능에 관한 연구

이수일,조봉수,김영욱,고광욱,조원근,김영실,강수용,황인경,조병만,김돈균 大韓産業醫學會 1997 대한직업환경의학회지 Vol.9 No.1

The authors examined human immunity indicators such as CD4, CD8, Natural Killer(NK) cell, IgG, IgA, and IgM, and heavy metals such as Pb, Cr, Cd to evaluate the health hazard of welders. We selected total 126 male subjects, 60 welders who had more than 5 year working history as an exposure group, and 66 office workers and medical college students as a control group. This immunity evaluation approach is the first newly designed study that has never been tried in past studies on welder's heath evaluation. And the results were as follows. 1. Total lymphocyte count of peripheral blood was significantly higher in welder group, 2,615±650 ea/㎕ compared with 2,368±681 ea/㎕ in control group(p>0.05). 2. The proportion of CD4, CD8, NK cell in welder group was 37.5±9.4%, 24.0±8.8%, and 21.0±9.5%, respectively, and 35.5±6.5%, 25.0±6.9%, and 19.6±8.8% in control group. CD4 and NK cell were slightly higher, and CD8 was slightly lower in welder group. but there was no statistical significance between two groups(p≥0.05). 3. IgG, IgA, and IgM in welder group were 15.9㎎/㎗, 2.7㎎/㎗ and 1.5㎎/㎗, respectively, and 15.6㎎/㎗, 2.9㎎/㎗ and 1.7㎎/㎗ in control group. There was no statistical significance between two groups(p≥0.05). 4. Blood lead, cadmium and chromium concentrations were 4.2±1.8㎍/㎗, 0.4±0.38㎍/㎗, 1.2±0.6㎍/㎗ in welder group and 3.2±1.7㎍/㎗, 0.44±0.29㎍/㎗, 1.1±0.6㎍/㎗ in control group, respectively, and these value were within normal ranges.

치과기공실의 작업공정별 소음에 관한 연구

조수열,남상룡 효성여자대학교 부설 한국환경위생연구소 1992 환경위생연구 Vol.2 No.1

본 연구는 치과기공실의 작업부서별, 1인작업시의 소음도를 조사하여 기본자료로 하고 복합공정시의 소음을 측정하여 70 dB이상의 소음 노출시간을 조사함으로서 전체 치과기공실의소음도를 추정하고, 치과기공실의 소음이 치과기공사에게 정신적, 정서적 , 생리적으로 어떠한영향을 미치는가를 설문조사하여 소음에 노출되어 있는 치과기공소의 환경위생 관리와 건강장해를 예방하기 위한 기초자료를 얻고자하는데 그 목적이 있으며 그 결과는 다음과 같다. 1. 작업부서변 1인 공정시 소음도는 각 작업부서별 모두 연마작업시 높은 수치를 나타냈으며, 그 정도는 70 dB이상이다. 2. 작업부서별 복합공정시 공정별 소음도는 1인 작업공정시보다 전체적으로 소음발생이증가하였는데, 소음도의 차이는 연마시보다 조용한 작업공정 시가 최소한 10 dB이상으로더 큰 차이가 나타났다. 3. 작업부서별 소음 노출시간은 80 dB이상에서는 복합공청시 도재기공부서(150분), 국부의치(120분), 관교의치기공(100분), 총의치기공(80분) 순으로 나타났다. 4. 작업실의 시간대변 소음정도는 연마작업시는 대부븐이 80 dB이상이고 Wax작업시는대부분이 75 dB이하로 나타났다. 5. 설문조사에서 치과기공사의 심리적 상태는 기공실 소음으로 인하석 거의 매일 짜증난다(14%), 가끔씩 짜증난다(29%)로 나타났고 정서적 불안감도 화가 잘 난다(19%)로나타났다. 6. 소음이 치과기공사의 신체에 미치는 영향은 기공일을 하는 동안 위장병에 대해서는위산과다 39%, 위궤방 11%, 위염 5%, 십이지궤양 3% 순으로 나타났고, 심장이 약한것 같다가 32%로 나타났다. 7. 소음이 치과기공사의 청력에 미치는 영향은 약해진다가 39%, 보통이다 33%, 정상이다14%로 나타났다. 치과기공실에서 발생되는 소음에 의해 치과기공사들이 심리적, 신체적으로 큰 영향을 받는것으로 나타났으므로 치과기공실의 작업환경관리에 대해 보다 많은 관심이 요구되며, 소음의발생을 줄일 수 있는 지속적인 연구가 요망된다. Degree of noise by personal dental laboratory working process anddegree of noise by complex dental laboratory working process were measuredseparately. The time of exposure to noise greater than 70 dB estimated on thebasis of afore-medntioned information. Questionarire were employed to investi-gate the mental, emotional and physiological effects of noise on dental techni-cians. The purpose of this study was to provide basic information on keepingdental technicians who are exposed to noise pollution in good working conditionand good health. Results obtained are as follows ; 1. Polishing process in each working part showed high degree of noisegreater than 70 dB in terms of degree of noise by personal working. 2. Degee of noise by complex working process in each workong part wasgreater than that of personal working process. 3. Time of exposure to noise complex working process the part of porcelain150 min., partial denture 120 min., crown and bridge 100 min., full denture80 min. 4. Degree of noise by time in dental laboratory was 80 dB in general forpolishing process and below 75 dB for waxing process. 5. Effects of noise on mental and emotional state of dental technicians she-wed that they felt irritated every day(14% ), irritated once in a while(39% ) andeasily get med(19% ). 6. Effects of noise on heart and stomach were hyper-gastric acid(38% ) ,gastric ulcer(11% ), gastritis(5% ), deuodenal ulcer(3% ) and weak hert function(32% ). 7. Effects of noise on the hearting ability were weak(39% ), moderate(33% )and normal(14% ). Data presented in this study demonstrated that noise in the dental laboratoryexerts profound effect on detal technicians mentally, physiologically and emotio-nally. In light of the above results, therefore, it appears advisable to devote subs-tantial interests on the management of working condition and put further(conti-nuing) effeorts in the ivestigation for reducing noise problem.

동물과 사람유래 Vancomycin 내성 장구균의 항균제 감수성 비교

조윤상,이희수,김종만,류판동,박용호,유한상,이문한 한국수의공중보건학회 2003 예방수의학회지 Vol.27 No.1

It has been recently reported the possibility in the bansfer of antimicrobial resistance to other animals and humans. In particular, vancomycin resistant enterococci (VRE), which have been known as a principal antimicrobial resistant bacteria in humans, have been increased as a pathogen of nosocomial infections. And then animal VRE were suspected as an origin of human VRE. In this study, we isolated Enterococcus spp. from animals, identified by bio- chemical tests, examined for antimicrobial susceptibility, and then compared the antimicrobial susceptibility of VRE among each other as well as human VRE. Enterococcus iecium (29%) was predominant in Enterococcus species (n=122) isolated from animal feces in this study. E. hirae, E. iecalis, E. casseliflam and E. gallinarum were also isolated as rates of 24%, 21%, 16% and 7%, respectively. The resistance of enterococci to penicillin and tetracycline were 66% and 78%, respectively, and the susceptibility of them to chloramphenicol was 66%. Antimicrobial susceptibility test has shown that 91% of VRE from humans (n=11) was susceptible to chloramphenicol and all resistant to penicillin, rifampin and streptomycin. Seventy-five percentage of VRE from chickens (n = 12) was susceptible to rifampin and resistances of them to penicillin, tetracycline and sbeptomycin were 75%, 83%, and l00%, respectively. Therefore, we confirmed the difference of antimicrobial susceptibility from animals and humans, and the antimicrobial susceptibility test could be one of the simple and useful methods for the epidemiological survey of VRE.

야뇨증 환아들의 심리사회적 특성에 대한 다기관 연구 : 행동 및 정서 문제를 중심으로

조수철,김재원,신민섭,황준원,한상원,박관현,이상돈,김경도,김건석,서홍진,이유식,정재용,김영균,문두건,남궁미경,한창희,조원열,김영식,배기수,이종국,정우영,신의진 大韓神經精神醫學會 2005 신경정신의학 Vol.44 No.6

Objectives : The aim of this study was to examine the behavioral and emotional problems associated with nocturnal enuresis in Korean children. Methods : Three hundred eighteen children with nocturnal enuresis, together with their parents, completed the Child Behavior Checklist (CBCL), Disruptive Behavior Disorder Scale according to DSM-IV (DBDS), Children's Depression Inventory (CDI), State-Trait Anxiety Inventory for Children (STAIC), and Piers-Harris Children's Self-Concept Scale (PHCSC). Ninety-three normal students were selected as the control group. Results : Compared to the normal control group, the mean scores with regard to the withdrawn, social problems, attention problems, delinquent behavior, aggressive behavior, externalizing problems and total problems profiles were significantly higher in the nocturnal enuresis group according to the CBCL results. The nocturnal enuresis group also scored significantly higher in the ADHD and ODD profiles of the DBDS. The nocturnal enuresis group was more depressed and anxious than the control group according to the results of the CDI and STAI. The mean score of the PHCSC was significantly lower in the nocturnal enuresis group when compared to the normal control group. Conclusion : The results of this study suggest that children with nocturnal enuresis in Korea have clinically relevant behavioral and emotional problems. The findings support the link between nocturnal enuresis and psychopathology in Korean children.

관광객의 환경의식이 생태관광태도에 미치는 영향

조진희,김수봉,김용범 한국환경과학회 2004 한국환경과학회지 Vol.13 No.1

Regarding to the ecotourism for environmental conservation, tourists's consciousness and attitude on environment should be dealt with importantly more than the mass tourism. The purpose of this study is to identify the effects of the tourist's environmental consciousness on the ecotourism attitudes. As a result, it was analysed that the more people had interested in environmental problems, positive activities in the environment, the more people had the ecotourism attitudes. This suggested that for development of the ecotourism, it were needed to change tourist's attitude to friendly environment, to make higher consciousness about environmental conservation.

Polytrop Blue B 및 hydroxydodecyl-trimethyl ammonium bromide에 依한 微量銅의 吸光度定量에 關한 硏究

趙誠烋,金永洙,鄭鐘南 朝鮮大學校 1977 綜合論文集 Vol.1977 No.-

We Can notice reaction of PolytropBlue B with Cu in the existance of hydroxydodecyl trimethyl. Ammonium bromide to make a blue ion-assossiation chelate. The chelate turns out stable in aquesous pyridine solution maximum absoption of this was measured at 591nm, and the absorbance is Constant from, pH, 8.0 to 9.2. When molar extintion Coefficient is 1.19×10??, very high Sensitivity was noticed. This Value is 8 times higher than that of batho-cupronin chelate. Considerable interference was detected from Co, Ni, Zn, U, Ce, Cr, Fe, and Sn. From over 0.2㎍ Cu/ml the absorbance follows Beer's Law.

중심 정맥 도관 348례의 임상적 고찰

조남수,김용배,임경준 대한응급의학회 1995 대한응급의학회지 Vol.6 No.2

To evaluate clinical trends, central venous catheterization of 348 in total performed at the Chosun University Hospital from January 1993 through December 1994 were analyzed clinically & statistically according to sex, age, department, used veins and complications. The results are as follows : 1) Considering sexual distribution, male patients were 61.2% and female patients were 38.8%. 2) According to age categories, fourth decade of life was most frequent. 3) According to departmental distribution, general surgery was 38.5%, chest surgery was 21.0% and orthopedic surgery was 12.9%. 4) Subclavian vein used most frequently (74.1%), and femoral vein accounted for 14.9%, extermal jugular vein 7.5% internal jugular vein 3.4%. 5) Complications associated with subclavian vein catheterization using infraclavicular approach occupied 15.1%(39 cases) of total subclavian vein catheterization(258 cases), and among these complications pneumothorax occupied 43.6%, subcutaneous hematoma 28.2%, local infection 15.4%.