신규개발된 제초제 metamifop 현탁농축액제에 대한 급성독성평가

이동연,이상훈,백경진,김태원,정두순,임종환,김명석,박병권,윤효인 충남대학교 수의과대학 동물의과학연구소 2004 動物醫科學硏究誌 Vol.12 No.-

Metamifop, (R)-2-[4-[(6-chloro-2-benzoxazolyloxyphenoxy]-N-(2-fluorophenyl)-N-methyl propanamide, was newly developed by Dongbu Hannong Chemicals in Korea. In the present study we conducted acute oral toxicity and acute dermal toxicity test. The values of LD_(50) of metamifop was found to be over 5,000 mg/kg for ICR mice. On the other hand, metamifop showed no acute dermal toxicity to SD rats.

Carbosulfan의 피부자극성, 안점막 자극성 및 피부감작성등의 알러지성 효과에 관한 연구

이상훈,이동연,백경진,김태원,정두순,임종환,김명석,박병권,윤효인 충남대학교 수의과대학 동물의과학연구소 2004 動物醫科學硏究誌 Vol.12 No.-

Many studies have been published on the human health effects of carbosulfan toxicity. Carbosulfan used as an insecticide can produce an irritating and allergenic effect when acting on the skin. In this study, a sensitization test on albino guinea pigs and intradermal reactivity and occular irritation test on albino rabbits were carried out with carbosulfan. Signs of acute skin inflammation appeared along with the clinical symptom of chronic dermatosis caused by the solution irritating characteristics. Moreover, carbosulfan showed severe eye irritation with conjuctival redness and severe opacity on cornea. Preventive measures should involve workers' obligatory instructions on the noxious impact on human skin and strict observance of industrial safety rules.

경연 대회를 통한 초ㆍ중고생의 창의력 신장 효과에 관한 연구

이희복,육근철,류해일,김현섭,김희수,박달원,유병환,김선효,김여상,서광수,변두원,서명석,배성효,박종석,심규철,이성희 공주대학교 과학교육연구소 2001 과학교육연구 Vol.32 No.1

미래 사회를 대비하기 위한 개인의 개성을 존중과 창의적인 능력을 지닌 인간을 양성을 목적으로 충청남도 지역의 초 ㆍ 중고등학생들을 대상으로 한 창의력 경연대회가 공주대학교 과학교육연구소에서 개최되었다. 충청남도 초 ㆍ중 ㆍ 고등학생들을 대상으로 실시한 창의력 경연대회는 창조적 아이디어를 내어 스스로 문제를 해결해 나갈 수 있는 교육 프로그램을 제공하는 좋은 기회였음이 확인되었으나, 일부의 팀에서만 참신하고 재미있는 아이디어들이 제안되었다. 여학생의 참가자 수가 상당히 증가하였으며, 대체적으로 입상권의 학생들의 상당 부분이 여학생이라는 것이 특이할만하다. 학년이 올라감에 따라서 창의적인 아이디어를 내는 양이나 질에 있어서 뒤떨어지는 것으로 분석되었으며, 토론 학습의 적응력이 미흡하고 발표력 및 청취력에 있어서도 떨어지는 것으로 나타났다. 따라서 중 ㆍ고등학교의 학교교육에서도 학생들에게 프로젝트형 탐구학습 프로그램의 적용은 물론 토론식 수습을 통한 학생들의 사고의 전환의 기회를 제공해야 할 것으로 사료된다. The creativity competition was held to foster the creativity of elementary and secondary school students in the Institute of Science Education, Kongju national University. It was found that the creativity competition effected on the improvement of inventing creative ideas and problem solving activities. But, only some competitors participated in semifinal and final contests, presented original and interesting ideas. More female students participated in competition than last year. More female participants were awarded a prize than males. Totally, participants were defective in discussion and communication, and presentation and listening ideas. Increasing grades correlated inversely with creativity and originality. There is need of inquiry project teaming programs and presenting opportunities of conversion of thinking by discussing instructions in school

자체정열 방법을 이용한 GR(Gate-Recessed) SOI

이충근,한명석,홍신남 한국항공대학교 1997 論文集 Vol.35 No.-

SOI(Silicon-On-Insulator)소자는 집적도의 향상, 단채널 효과의 감소, 임계전압 이하에서 기울기 향상, 높은 이동도, latch-up 제거 등의 우수한 이점을 제공한다. 그러나 SOI소자는 current kink와 early breakdown과 같은 floating-body effect를 나타낸다. Floating-body effect를 줄이기 위해 fully depleted SOI를 사용해야 하나 면저항이 크기 때문에 GR(gate-recessed) SOI가 제안되었다. GR SOI는 floating-body effect와 면저항을 줄일 수 있지만 공정상 복잡성이 따른다. 이 논문에서는 self-alignment method를 이용한 GR SOI 를 제안하여 이러한 문제를 해결하였다. 제안되 구조를 시뮬레이션한 결과 드레인 전류의 크기 향상, floating-body effect제거를 위한 imapct-ionization current를 감소시킬 수 있었다. SOI(Silicon-On-Insulator) devices offer unique advantages such as reduction in short channel effects, improvement of subthreshold slope, higher mobility, latch-up free nature and so on. But these devices have two problems; floating-body effect causing current kink and early breakdown effect. Fully depleted SOI reduces floating-body effect, but it increases sheet resistances. So gate-recessed SOI is proposed. Gate-recessed SOI can reduce sheet resistance and floating-body effect, but is processing step are complicated. In this paper, gate-recessed SOI using selt-alignment method is proposed to solve the above problems. Proposed structure improved drain current level, decreased sheep resistances of sourcd/drain regions and impact ionization current for removal floating-body effect

포공령 물추출물이 뱌양 인체 구강유상피암종세포에 미치는 항암효과

이명호,한두석 원광대학교 생체재료·매식연구소 1998 원광생체재료·매식 Vol.7 No.2

In order to develop antitumor agent which indicates weak side effects and strong antitumor activity, antitumor effects of taraxaci herba water soluble extract was evaluated by MTT assay and SRB assay of colorimetric assay methods on the cultured human oral epitheloid carcinoma cells (KB cells). KB cells were cultured in RPMI 1640 media containing 10% fetal bovine serum, antibiotics and fungizone. After incubation for 24 hrs, the cells were treated with taraxaci herba water soluble extracts by dose dependent manner for 48 hrs under the same condition. The MTT and SRB quantity were measured by ELISA reader(Spectra Max 250, USA). The microscopic study was carried out to observed morphological change, Ag-NOR(argyrophylic nucleolar organizer region) number and PAS positive reacton of cultured KB cells. The results were as follows ; 1. The MTT and SRB quantity were significantly decreased in cultured KB cells treated with 10^-2 ㎎/㎖ and 10^-3 ㎎/㎖ concentration compared with control. 2. The number of Ag-NORs was significantly decreased in cultured KB cells treated with 10^-2 ㎎/㎖ concentration of taraxaci herba soluble extracts and the rate of Ag-NORs was shift left side(one Ag-NORs/nucleus was increased and five Ag-NORs/nucleus were decreased) by high concentration. 3. PAS reaction of cultured KB cells treated with 10^-2 ㎎/㎖ and 10^-3 ㎎/㎖ concentration was changed to negative. These results indicate that taraxaci herba soluble extracts may be contain antitumor compounds.

열처리 방법에 따른 접합특성에 관한 연구

한명석,이병학,홍신남 한국항공대학교 1995 論文集 Vol.33 No.-

0.2㎛ 이하의 shallow pㆍ-ⁿ 접합을 형성하기 위하여 주입 에너지가 45KeV 인 As이온과 Ge이온으로 섬비정질화하였고, dopant로는 BF₂ 이논을 24keV로 주입하였으며 dose는 2×10?cm?이다. 열처리 조건은 FA 850℃/min, RTA 1000℃/10sec, RTA 1000℃/10sec와 FA 850℃/min, FA 850℃/40min와 RTA 1000℃/10sec이었다. 또한 RTA의 온도 변화를 주어 FA와의 혼합 열처리를 시뮬레이션한 결과로 RTA의 온도가 FA보다 높은경우에 FA+RTA가 RTA+RA보다 접합깊이가 면저항에서 유리한 특성을 나타내고 있음을 알 수 있었다. 실험결과에서도 시뮬레이션 결과와 동일하게 선비정질화를 이용한 shallow접합의 형성시 Ge으로 선비정질화한 후 FA+RTA의 열처리가 RTA+FA보다 이온 주입후의 결정결함의 제거에 의해 접합깊이와 면저항의 특성이 우수함을 알 수 있었다. To form sub 0.2㎛ ?? junctions, As and Ge ions of 45keV implatation energy were used for preamorphization and BF₂ was used as dopant ion with 25keV implantation energy and the dose of ??. annealing was carried out in the manner of FA 850℃/40min, RTA 1000℃/10sec plus FA 850℃/40min and FA 850℃40min plus RTA 1000℃/sec. Also simulation was performed when the samples were annealed with FA plus the various temperatures of RTA. In respect of junction depth and sheet resistance, FA+RTA was better than RTA+FA, when the temperature of RTA was larger than FA. Tp Form shallow ?? junction, FA+RTA annealing method with GE ion preamorphization showed better junction characteristics than RTA+FA fir junction depth and sheet resiatance via point-defect removal.

2.4GHzWLAN용스위치설계를위한GaAspHEMT소자모델링

한명우,이창석 한밭대학교 정보통신전문대학원 2005 정보통신전문대학원 논문집 Vol.3 No.1

본 논문에서는 2.4GHz WLAN용 스위치 설계를 위한 GaAs pHEMT 소자 모델링을 수행하였다. 스위치 소자 모델로는 공정 파라미터의 함수로써 스위치 특성의 예측이 가능하고, 순방향과 역방향 특성이 대칭성을 갖는 Curtice2(Curtice-Quadratic GaAsFET)모델을 사용하였다. 스위치 동작 영역과 일반적인 스위치 증폭영역에서 소신호 및 대신호 모델들을 각각 추출하였고, 측정된 결과와 모델링 한 결과들을 비교함으로써 제안된 방법이 스위치 설계에 타당함을 확인하였다. In this paper, we have performed GaAs pHEMT device modeling for the switch design of 2.4GHz WLAN. For the switch device model, we have used Curtice2(Curtice-Quadratic GaAsFET) model, which has symmetrical forward and backward characteristics and possible for the prediction of the switch characteristics as a function of process parameters. We have extracted small signal and large signal models at the switch operating region and the general switch amplified region, respectively. By comparing the measured results with the modeling results, we have verified the proposed method is appropriate for the switch design.

한국 고령자계층의 건강증진행동에 관한 연구

김석일,이명섭,김대권 한국스포츠리서치 2003 한국 스포츠 리서치 Vol.14 No.1

This study was undertaken to grasp health-promoting behavior of the elderly and to identify self-rating health status, demographic characteristics related to them in order to facilitate nursing intervention for health promotion of the population. The subjects for this study were 225 old persons visiting five general social welfare centers located in Tague. Data were collected by self-reported questionnaires from August, 2002to February, 2003. Questionnaires were Northern Illinois University's Health Self-Rating Scale, Walker and others' health Promotion Lifestyles Profile. Analysis of the data was done by the SAS program for descriptive statistics, t-test, ANOVA, and pearson Correlation Coefficient. The results were summarized as follows: 1. There were significant differences in health-promoting behavior according to sex)t=3.28, p=.0011), marital status(F=8.98, p=.0003), and average monthly pocket money(F=4.99, p=.0007). 2. For the participation in health-promoting behavior, the mean score was 2.96 and range was from 3.40 to 2.34. The factors of high mean score were sedentary life(3.40), regular diet(3.37), and factors of low mean score were stress management(2.34), accountability for health(2.60). 3. The mean score of health self=rating was 2.19(range 4-14) and was considered low. 4. Self-rating health status was correlated positively with health-promoting behavior(r=.1783, p=.0106). On the basis of the above findings, the followings are recommended; 1. Nursing strategies need to be developed considering personal demographic characteristics of the elderly. 2. Nursing interventions enhancing self-actualization, accountability for health, stress management of the elderly must be provided.

SOI 기판에 형성된 MOSFET의 특성 연구

한명석,이찬희,홍신남 한국항공대학교 1995 論文集 Vol.33 No.-

Thin film SOI 소자는 short channel effect 감소, subthreshold slop의 개선, 높은 이동도, 낮은 기생 캐패시터, latch-up현상이 없는 등의 여러가지 장점들을 가지고 있다. 이것이 ULSI에 대해 실현 가능한 기술이 된 것은 최근에 발달된 양질의 thin film SOI 기관 제작기술에 기인한 것이다. 그렇지만 current kink와 early breakdown 같은 floating body effect와 source/drain 저항의 증가라는 두가지의 큰 문제점을 가지고 있다. 본 연구에서는 concave 구조를 가지는 SOI MOSFET 형태를 통해 문제를 풀어보고자 하였다. 제안된 concave SOI 구조는 항복전압을 높이고 드레인 영역에서의 전계를 감소시켜 kink 현상의 원인이 되는 impact ionization이 발생할 확률을 줄이는 결과를 얻을 수 있었다. Thin-film SOR(Silicon-On-Insulator) devices offer unique advantages such as reduction in short channel effects, improvement of subthreshold slope, higher mobility, low parasitic capacitance, latch-up free natere, and so on. This is available technology for ULSI due to recent advances in high quality thin film SOI process technology. However, Thin film SOI devices have several problems-floating body effects, current kink, early breakdown effects, increase in parasitic source/drain resistances. In this paper, a SOI MOSFET with concave structure is analyzed for a sub-half micron regime to solve the above problems. Proposed concave SOI structure showed the increased breakdown voltage and the decreased impact ionization due to the lower electric field near the drain region.

소양호의 어류군집 동태

최재석,이광열,장영수,고명훈,권오길,김범철 한국어류학회 2003 韓國魚類學會誌 Vol.15 No.2

2001년 4월부터 2002년 9월까지 소양호의 어류군집 동태를 조사한 결과는 다음과 같다. 조사된 어류는 총 11과 38종이었다. 한국 고유종은 P. tenuicorpus, C. splendidus, S. gracilis majimae, S. japonicus coreanus, H. mylodon, G. brevibarba, M. yaluensis, M. longidorsalis, C. koreensis, C. rotundieaudata, S. microdorsalis, P. koreanus, L. andersoni, C. herzi, O. patycephala 등 15종(40.54%)이었다. 우점종은 Z. platypus(39.60%), H. olidus(39.47%), S. gracilis majimae(12.24%), S. japonics coreanus(2.11%), P. fulvidraco(1.48%), L. macrochirus(1.40%) 등이었다. 채집된 어종들의 생체량을 보면 Z. platypus가 19.48㎏, H. olidus로 8.75㎏, C.cuvieri 7.42㎏, L. maeroehirus 7.39㎏, H. labeo 6.85㎏의 순으로 나타났다. 소양호에서 확인된 도입종은 A. japonica, H. eigenmanni, H. olidus, P. altivelis, C. urotaenius, R. giurinus, T. brevispinis, C. carpio(Israeli type), c. euvieri, Onchorhynchus mykiss, L. macrochirus, M. salmoides, I. puntatus 등 13종이었다. 이 중 C. carpio(Israeli type), C. cuvieri, Onchorhynchus mykiss, L macrochirus, M. salmoides, I. puntatus는 국외종이며, A. japonica, H. eigenmanni, H. olidus, P. altivelis, C. urotaenius, R. giurinus, T. brevispinis 등은 국내 다른 하천ㅇ로부터 유입된 종이다. The dynamics of the fish community in Lake Soyang, Korea, was investigated from April 2001 to September 2002. During the surveyed period 38 species belonging 11 families were collected. There were 15 Korean endemic species 39.47%, including Pseudopungtungia tenuicorpus, Coreoleuciscus splendidus, Squalidus gracilis majimae, S. japonicus coreanus, Hemibarbus mylodon, Gobiobotia brevibarba, Microphysogobio yaluensis, Microphysogobio longidorsalis, Iksookimia koreensis, Iksookimia rotundicaudata, Silurus microdorsalis, Pseudobagrus koreanus, Liobagrus andersoni, Coreoperca herzi, and Odontobutis platycephala. Dominant species were Zacco platypus (39.60%), Hypomesus olidus (31.70%), Squalidus gracilis majimae (12.24%), Squalidus japonicus coreanus (2.11%), Pseudobagrus fulvidraco (1.48%) and Lepomis macrochirus (1.40%). The biomass of collected fishes were Zacco platypus (19.48 ㎏), Hypomes olidus (8.75 ㎏), Carassilus cuvieri (7.42 ㎏), Lepomis macrochirus (7.39 ㎏) and Hemibarbus labeo (6.85 ㎏). Of the 13 introduced fishes in Lake Soyang Cyprinus carpio (israeli type), Carassius cuvieri, Onchorhynchus mykiss, Lepomis macrochirus, Micropterus salmoides and Ictalurus puntatus were originated from foreign countries but Anguilla japonica, Hemiculter eigenmanni, Hypomesus olidus, Plecoglossus altivelis, Chaenogobius urotaenius, Rhinogobius giurinus. Thridentiger brevispinis were introduced from other native river systems.