모잘록병균(Pythium ultimum)에 대한 N-Phenylbenzenesulfonamide 유도체의 살균활성에 미치는 구조적 특성

조윤기,장기운,성낙도 충남대학교 농업과학연구소 2008 농업과학연구 Vol.35 No.1

The structural characteristics that influence on the fungicidal activities of N-phenylbenzenesulfonamide (1∼24) and N-phenyltheinylsulfonamide (25∼30) derivatives against Dampping-off (Pythium ultimum) were discussed quantitatively using the models of molecular holographic quantitative structure-activity relationships (HQSAR). From the based on these findings, the statistical results of the optimized HQSAR F-3 model showed better predictablity (r² cv. or q²=0.581) and correlation coefficient (r²_(ncv).=0.963). And, from the analytical results of the atomic contribution maps on the fungicidal activities, the most active compound is R₁= 2-fluoro-4-chloro substituent (4) and the most inactive one is R₁=4-methoxy substituent (20). It was found that the 2-fluoro-4-chlorophenyl group as a R₁-group was an important structure and a characteristic factor not only for herbicidal activity but also for fungicidal activity.

다결정을 이용한 실온에서의 분광 홀버닝 광메모리 구현에 관한 연구

조재헌,백운식,장기완 경희대학교 레이저공학연구소 2001 레이저공학 Vol.12 No.-

The extremely high data densities can be obtained by spectral holeburning, so persistent holeburning has been studied on crystal that doped sm2+ ions at room temperature. To improve performance of persistent spectral holeburning system, we replace a dye laser system by our Littman type external cavity tunable laser diode system.

심전도의 디지털 기록화 모듈과 개인용컴퓨터 저장/분석시스템의 개발

조명찬,김기석,배장환,연태진,김동운,이태수,전은석,김유진 충북대학교 의학연구소 2001 忠北醫大學術誌 Vol.11 No.2

연구목적: 현재 우리나라의 의료분야에서는 정보기술의 발전으로 처방 전달 시스템과 전자차트의 활용이 상용화 되고 있으나 병원내에서 가장 많이 처방되고 검사되는 12-유도 심전도의 디지털화와 이에 연계된 심전도 결과의 개인용 컴퓨터로의 저장, 인터넷을 이용한 병원으로의 전송이나 타 기관에서의 심전도 결과의 동시 관찰 등에 관한 기술 등은 개발되지 못한 상태이다. 이에 본 연구에서는 심전도를 디지털화하며 저장이 가능한 PC 모듈을 개발하고 심전도 결과를 병원 전산 시스템에 포함시켜 병원내외에서 편리하게 조회, 검색할 수 있는 디지털 인터페이스를 개발하려 하였다. 재료 및 방법 : 낮은 전력에서 잡음특성이 우수한 대역여파기와 증폭기를 설계하였으며 각종기능이 내장된 고신뢰성 프로세서를 채택하였으며 전원 잡음이 고려된 필터와 전원 회로 설계로 하드웨어를 개발하였다. MSC 6.0과 Visual Basic 6.0을 바탕으로 하여 active X 모듈화를 유도하고 조회용 PC에서의 복원과 PACS로의 연동을 통해 순환기내과용 PACS 개발이 가능하도록 소프트웨어를 준비하였다. 결과: 심전도 검사자가 쉽게 장착, 검사가 가능한 소형화된 측정 모듈을 개발하였고 극저전류에서 동작이 가능하였으며 우수한 데이터의 압축 및 복원률을 구현하였다. 결론: 이번 심전도 디지털 모듈의 개발로 기존의 감광지에 의존하던 심전도 결과의 보존과 보관공간에 의한 경제적인 손실을 상당 부분 해결할 수 있으며 OCS에 연계된 결과로 인해 원내에서의 다면적 진료가 가능하다. 이번 연구에서 개발된 기술은 향후 디지털화된 심전도 기록장치와 같은 고부가 의료장치의 국산화와 광파일 의무기록 시스템이나 검사물의 무선 전송에 채용되어 의료 전달 체계나 응급체계의 발전에 기여하리라 사료된다. Purpose : The progressed communication technology commercialized the order communication system ( OCS) and the electric medical records( EMR) in the field of medicine in Korea. However, technologies of digitalization such as recording to personal computer, transfer to internet and simultaneous observation of electrocardiogram ( ECG) recorded at the different center were not realized yet. This study tried to invent personal computer module that can digitalize and record of the ECG and design the digital interface that can approach and search digitalized ECG in various part of hospital simultaneously. Materials and Methods : We had designed high-fidelity digital filter and amplifier which can work in very low voltage, had selected multifunctioned microprocessor. Activation X modulation was conducted by MSC 6.0 and Visual Basic 6.0. Softwares were prepared for the transfer of ECG informations from terminal PC to PACS and cardiologic PACS was designed for future application. Results : We have developed the small, portable, very low voltage managed ECG module and high quality digitalized information compression software in OCS and PACS. Conclusion : This invented ECG digital archive module can save hospital cost by substitution of ECG papers for digital storage or on-line storage, therefore ECG data can be handled in multisector of the hospital and through telemedicine. This technology can be applied to domestic ECG digitalizing device development and effective medical transfer system by adoption cordless medical information delivery.

비ST분절상승 급성관동맥 증후군 환자에서 N-terminal Pro B-type Natriuretic Peptide(NT-proBNP)를 이용한 관동맥 협착의 중증도 및 초기 위험도 평가

김기석,한혜숙,황경국,연태진,김동운,조명찬 대한순환기학회 2004 Korean Circulation Journal Vol.34 No.2

효모에서 분리한 단백 메틸레스의 특성에 관한 연구

김보경,백운기,조만희,김창세 순천향의학연구소 1997 Journal of Soonchunhyang Medical Science Vol.3 No.2

A cytochrome C - specific protein methylase Ⅲ was purified approximately 63 - fold from Saccharomyces cerevisiae. The unmethylated cytochrome C served as substrate for the enzyme. Horse heart apocytochrome C was found to be a better substrate than the native horse heart cytochrome C. This observation suggests that the in vivo methylation of cytochrome C in the yeast probably occurs before cytochrome C become attached to the mitochondria. In partly purified protein methylase Ⅲ the optimun pH is about 9.0, the enzyme activity is linearly proportional to the amount of enzyme protein up to about 30㎍ and also to time up to 15min. The Km values for horse heart cytochrome C and S - adenosyl - L- methionine were 1.33mM and 40㎛, respectively. S - adenosyl - L - homocysteine was found to be a competitive inhibitor for S - adenosyl - L - methionine, and the Ki value was 2.7 μM. The molecular weight of the enzyme was approximately 97,000, determined on sephadex S- 200 gel filtration. The regulation of cellular cytochrome C and the protein methylase Ⅲ are not coordinately related in a parallel manner.

잡견에서 Rapid Atrial Pacing에 의한 심방의 전기적 재현성과 이의 회복

남기병,김동운,차성일,이석재,홍종면,임승운,나기정,조명찬 대한순환기학회 1998 Korean Circulation Journal Vol.28 No.6

탈지 환원유에서 Bifidobacterium longum의 호기성 고농도 배양에 관한 연구

구동환,하상우,조수현,박기문,김동운,강국희 성균관대학교 생명과학자원연구소 1997 生命資源科學硏究 Vol.4 No.1

The objectives of this study were to investigate the optimal condition for growth and highly concenterated culture of Bifidobacterium longum (Bif longum). The effects of additives were compared with titratable acidity and viable cell counts, and 10% reconstituted skim milk (no additive) was used as a control. Correlation coefficient for the growth of Bif. longun between CO_2 anaerobic jar method and overalaid medium method was R=0.99. When 1% Bif. longurn was inoculated on 12%, 14%, and 16% reconstituted skim-milk, viable cell counts were 8.60, 8.89, and 8.93 Log CFU/ml, respectively. When Lactose, Glucose, Glucosamine, Fructose, Peptone, N-acethyl-D-glucosamine, D-galactose, and liver extract were added to 16% reconstituted skim-milk, the viable cell counts were 8.61, 9.05, 9.15, 9.24, 8.82, 9.75, 9.17, and 9.64 Log CFU/ml, respectively. Therefore, D-galactose, liver extract, and N-acethyl-D-glucosamine were selected as final additives. When Bif longum was inoculated on Fermentor-I (16% reconstituted skim milk containing 0.1% yeast extract, 0.5% D-galactose and 0.5% liver extract), Fermentor-II (16% reconstituted skim milk containing 0.190% yeast extract, 0.590% N-acethyl-D-glucosamine and 0.5% liver extract), Batch culture-I (16% reconstituted skim milk containing 0.1% yeast extract, 0.5% D-galactose and 0.5% liver extract), and Batch culture-II (16% reconstituted skim milk containing 0.1% yeast extract, 0.5% N-acethyl-D-glucosamine and 0.5% liver extract), viable cell counts were 10.46, 9.37, 9.03, and 8.83 Log CFU/ml, respectively. Although liver extract was the important additive for the highly concentrated culture of Bif. longum in this study, it caused serious off-flavor when liver extract-1 (contained cell mass) was added to Fermentor culture. However, flavor was improved when liver extract-2 which was removed cell mass, was used instead of liver extract-1. Addition of 2% liver extract-II and 1% D-galactose had the similar effect with addition of 0.5% Liver extract-I and 0.5% D-galactose on the growth of Bif. longum.

Microstructure-dependent thermoelectric properties of polycrystalline InGaO₃(ZnO)₂ superlattice films

Cho, Sung Woon,Baek, Seung Ki,Kim, Da Eun,Kim, Yunseok,Cho, Hyung Koun American Vacuum Society 2017 Journal of vacuum science & technology. an officia Vol.35 No.1

공장지역에서 주거지역으로의 대지용도 변경시 소음현황 및 관련법규

조영운(Cho Young-Woon),주문기(Ju Mun-Ki),오양기(Oh Yang-ki) 한국건축친환경설비학회 2009 한국건축친환경설비학회 학술발표대회 논문집 Vol.2009 No.10

佛敎學報(불교학보)를 통해 본 한국불교연구의 동향

이기운(Ki Woon Lee),조기룡(Ki Ryong Cho),윤기엽(Ki Yeop Yoon) 동국대학교 불교문화연구원 2012 佛敎學報 Vol.0 No.63

『불교학보』는 동국대 불교문화연구원에서 발간하는 불교학 전문 학술지로서, 불교교학 불교사 불교문화 전반에 관한 논문을 게재하고 있다. 이 논문집은 1962년 창설된 불교문화연구소에서 이듬해 창간호를 시작으로 2012년 12월 현재 50년 동안 63집을 발간하고 있다. 불교계에 이렇다 할 학술논문집이 없었을 때, 불교계 최초로 창간되어 그동안 불교학자들의 학문적 업적을 발표하는 대변자로서 역할을 충실히 해왔으며, 한국 불교학의 흐름을 보여주고 새로운 학문적 방향을 제시하는 선구 논문집으로서 소임을 다해왔다. 이제 연구원 개원 50주년 63집을 발간하면서, 그동안의 연구성과를 회고하고 불교학보의 정체성을 확인하고 새로운 50년 불교학보의 나아갈 길을 전망하고자 이 글은 기획되었다. 그동안 불교학보게재논문의 동향을 보면, 다음의 몇가지로 정리 할 수 있다. 첫째, 한국불교의 각성을 통하여 한국불교의 정체성을 확인하였다는 점이다. 게재 논문들은 한국불교의 각성을 통하여 교학사상과 불교사, 불교신앙과 문화에 있어서, 한국불교의 주체성을 밝히고자 노력하였다는 것이다. 둘째, 교학연구의 탈근대화를 이끌었다는 것이다. 동국대학교가 세워지면서 불교계에는 비로소 현대적 불교교육이 실시되어 불교학자들이 배출되었다. 이들을 중심으로 한 현대적 불교학의 성과들은 『불교학보』를 통하여 학계에 소개되면서 현대적 불교학으로서 학문경향이 학계에서 자리잡는데 선도적 역할을 하게 되었다. 셋째, 종파의 탐구와 禪學의 연구가 깊이 있게 이루어지면서 근본불교부터 대승불교에 이르는 교파의 교학사상을 바로 밝히려는 노력과 선학의 체계적 연구가 이루어졌다는 점이다. 넷째, 고자료의 발굴을 통하여 한국 불교학 학문적 발전에 기여했다는 점이다. 다섯째, 전통적인 불교학 외에 현대과학과 의학 예술과 관련된 다양한 응용 불교학이 소개되었다. 다음은 앞으로 『불교학보』가 나아갈 길에 대해서는 한국불교학의 정체성을 바로 세우고 미래불교의 비젼을 다음 몇 가지로 제시하였다. 첫째는 1960년대 이후 2000년대에 이르는 동안 한국 불교학의 硏究推移를 통해서 한국 불교학의 정체성을 이어가고, 한국 불교학의 학문적 토대를 마련해주어야 한다는 것이다. 둘째는 앞으로 전통 불교학을 기반으로 응용 불교학을 더욱 진흥시키는데 초석이 되어야 한다는 점이다. 셋째는 불교학계의 권위지로서의 위상을 유지 발전시키고, 우수한 신진학자의 학문적 성과를 발표하는 등용문의 역할을 다해야 한다는 것이다. 끝으로 이와 같은 『불교학보』의 방향설정을 통하여, 우리논문집은 국내저명학술 지로서 만족하지 않고 불교학계의 국제저명학술지로 지향점을 두어 한국 불교학을 국제 불교학계에 널리 알리는 데에도 게을리 하지 않아야 한다는 것이다. The Bulgyohakbo(Journal for the Buddhist Studies; 佛敎學報) is a professional academic journal issued by the Institute for Buddhist Culture at Dongguk University, and it is publishing treatises in general on Buddhist doctrinal studies, the history of Buddhism, and Buddhist culture. Beginning with the first issue in 1963 after the foundation of the Institute for Buddhist Culture in 1962, it has published 63 treatise collections as of Dec. 2012 for 50 years. When there were no treatise collections to speak of, it started its publication for the first time in the Buddhist community. Since publishing its first issue, it has faithfully played a role of a spokesperson presenting the academic achievements of Buddhist scholars, and it has filled its role of a pioneering collection of treatises showing the flow of the Korean Buddhist Research and proposing new directions for the Buddhist research. While we publish the 63rd treatise collection in commemoration of 50th Anniversary of the institute, this writing was planned in order to look back on its academic achievements, ascertain its identity, and to put its course during its new 50 years into perspective. If we get a full review of the treatises which was published in the Bulgyohakbo, that can be summarized as follows. First, the treatises published in the magazine confirmed the identity of Korean Buddhism through disillusion toward Korean Buddhism. This means that they tried to clarify the independence of Korean Buddhism in respect of Buddhist philosophy, the history of Buddhism, Buddhist faith, and Buddhist culture through reopening their eyes to Korean Buddhism. Secondly, they led the modernization of Buddhist doctrinal studies. After Dongguk University was founded, modern Buddhist education was conducted in the Buddhist community, and Buddhist scholars began to be turned out. Their achievements in the field of modern Buddhist research were introduced to the academic world through the Bulgyohakbo, so that this magazine came to play a leading role in establishing an academic trend as modern Buddhist research in the academic circles. Thirdly, as research on Buddhist orders and Seon studies was done in depth, the efforts to correctly illuminate the doctrinal philosophies of all denominations from the fundamental Buddhism to Mahayana Buddhism were made, and a systematic research on Seon studies was done. Fourthly, the excavation of old materials contributed to the academic development of Korean Buddhist research. Fifthly, diverse applied Buddhist studies in relation to modern science, medicine, and art besides the traditional Buddhist research have been introduced. Next, regarding the course this Bulgyohakbo should take, as far as the task to set the identity of Korean Buddhist studies right and the vision of the future Buddhism First, on the basis of the research progress of Korean Buddhist research from 1960s to 2000s, it should keep the identity of Korean Buddhism, and it should prepare the academic foundation of Korean Buddhist studies. Secondly, it should become the cornerstone of the promotion of applied Buddhist research on the basis of the traditional Buddhist research. Thirdly, it should maintain and develop the status of an authoritative journal in the Buddhist academic circles, and it should fulfill the role of the gateway to the publication of the academic achievements by excellent rising scholars. Finally, through establishing these directions for the Bulgyohakbo, our collection of treatises should aspire toward a well-known international academic journal, never satisfied with the status of a famous Korean academic journal, so that it should show no neglect of promulgating Korean Buddhist studies to the international Buddhist community.