고요산혈증의 위험인자 : 아산시 지역 주민을 대상으로

김용배,장원기,황보영,김화성,안규동,이병국,이용진,이종은,이준숙,이찬구,이한정,이성수 순천향대학교 2006 Journal of Soonchunhyang Medical Science Vol.12 No.1

Objective : Serum uric acid has now been identified as a marker for a number of metabolic and hemodynamic abnormalities. The aim of this study is to evaluate risk factors which influence hyperuricemia in the citizens of Asan. Method : The study design was cross-sectional and research subjects were 1086 citizens of Asan. General characteristics, cigarette smoking, alcohol consumption, and past history were obtained by interview using a structural questionnaire. Also, we measured height, weight and blood pressure, and serum uric acid of the subjects. Results : The mean serum uric acid level was 5.27 ㎎/㎗ in men and 4.01 ㎎/㎗, in women, In the multiple logistic regression analysis, statically significant risk factors of hyperuhcemia were gender, body mass index, blood lead concentration, and serum creatinine. Conclusion : Our results suggest that gender, body mass index, blood lead concentration, and serum creatinine might be the most important risk factors of hyperurcemia. Education program as well as routine check-up for serum uric acid was highly recommended for the effective prevention of hyperuricemia.

DAP 신념에 근거한 유아과학 교수·학습모형의 현장적용 효과

이정화,이미은 미래유아교육학회 2003 미래유아교육학회지 Vol.10 No.4

DAP(Developmentally Appropriate Practice)는 유아교육실제의 질을 진단ㆍ평가하는 타당한 기준으로 인정받고 있을 뿐 아니라 유아교육과정의 설계나 프로그램 개발에 고려해야 할 준거로 널리 활용되고 있다. 본 연구는 DAP 신법에 근거하여 만들어진 절차화된 유아과학 교수ㆍ학습모형(이정화, 2002)을 유아교육 현장에 적용하여 그 효과를 검증해 보고자 하였다. 이를 위해 연구자들은 두 가지 교수학습방법(DAP 신념에 근거한 유아과학 수업모형과 전통적 수업모형)을 적용한 과학활동 프로그램을 구성, 처치한 후 유아들의 과학적 호기심 및 과학적 과정 기능의 향상 정도를 살펴보았다. 연구결과 DAP 신념에 근거한 절차화된 유아과학 교수ㆍ학습모형에 의한 과학활동 프로그램에 참여한 유아들이 전통적 교수법에 의한 과학활동 프로그램에 참여한 유아들보다 유의하게 높은 향상을 보였음이 확인되었다. The purpose of this study was to examine the effects of a developmently appropriate model of teaching science(DAP model) which is developed by Lee Jeong-Hwa(2002) on children’s curiosity and scientific process skills. Two research questions were made from the review of the literature, as follows ; 1. Are there any differences in science curiosity between children in an experimental and a control group? 2. Are there any differences in science process skills between children in an experimental and a control group? To answer the questions, forty five-year-old children attending a preschool in Busan participated in this study. They were randomly assigned to either an experimental or a control group. Children in the experimental group, took part in eight 40~45 minute sessions of science program based on the DAP model; whereas, their counterparts in the same sessions of a traditional science program. After the sessions of each program, all children were tested on the science processing skill test and the science curiosity test. The children who took the DAP model received higher achievement than their counterparts on curiosity and scientific process skills. From the results, the researchers suggest to apply the DAP model of teaching science for young children in the education field.

1995-96년 한반도 남동부 지역의 미소지진 자료를 이용한 지각구조 모델의 비교 연구

이기화,정태웅,Lee, Gi Hwa,Jeong, Tae Ung 한국지구물리물리탐사학회 1999 지구물리 Vol.2 No.1

한국자원연구소 지진관측망의 1995-96년 미소지진 자료를 바탕으로 한반도 남동지역의 지각구조에 대하여, Lee (1979), 김상조·김소구(1983), 김성균·정부흥(1985)의 세 지각 모델 중 어느 것이 잔차의 최소자승을 만족하는지 검증하였다. 세 모델 잔차의 뚜렷한 차이가 관찰되지 않았으나, Lee 의 지각 모델이 약간 깊은 진원을 산출하는 경향이 있다. 한반도 지각의 층상구조는 아직 명백하지 않으므로 앞으로 더 많은 자연지진 자료 또는 인공지진 자료를 통해서 규명되어져야 한다. Using the microearthquake data acquired from 1995 to 1996 through the seismic network operated by the Korea Institute of Geology, Mining & Materials (KIGAM), the three P-wave velocity models proposed by Lee (1979), Kim·Kim (1983) and Kim·Jung (1985) concerning the structure of the southeastern part of the Korean peninsula were examined in terms of the least square errors of the P-wave arrival times. The three models do not differ significantly in arrival time residuals except that the Lee's model gives slightly deeper focuses than the others. The layering of the crust of the peninsula is not clear as yet and to be studied by more earthquake and explosion data in the future.

Plant regeneration from callus of Iris odaesanensis Y. N. Lee native to Korea via organogenesis

Bae, Kee-Hwa,Yoo, Kyoung-Hwa,Lee, Mi-Hyun,Jeong, Jae-Hun,Choi, Yong-Eui,Yoon, Eui-Soo The Korean Society of Plant Biotechnology 2013 식물생명공학회지 Vol.40 No.3

Iris odaesanensis Y. N. Lee. is an important endangered and native plant belonging to the family Iridaceae in Korea. This study describes a method for rapid micropropagation of this species via from leaf, rhizome and root explants derived calli. Leaf, rhizome and root explants were cultured on Murashige and Skoog (MS) medium supplemented with 2,4-dichlorophenoxy acetic acid (2,4-D) for callus induction. Rhizome explants yielded calli at a frequency of 72% when cultured at 1.0 mg/l 2,4-D. Calli were maintained at 1.0 mg/l 2,4-D. These calli were transferred to MS medium supplemented with 0, 0.5, 1.0, and 2.0 mg/l 2,4-D in combination with 0, 0.5, 1.0, and 3.0 mg/l BA for adventitious shoot induction. The highest number of adventitious shoot (228.9 per petri-dish) were formed at 1.0 mg/l 2,4-D and 1.0 mg/l BA. WPM medium was the best to convert calli into plantlets, where up to 98.2% of calli were regenerated into plantlets. This in vitro propagation protocol should be useful for conservation of this endangered plant.

화병(火病)을 동반한 갱년기 환자 치험 5례

송유림 ( Yu-rim Song ),박경미 ( Kyung-mi Park ),양승정 ( Seung-jeong Yang ),이은규 ( Eun-kyu Lee ),김혜화 ( Hye-hwa Kim ),조성희 ( Seong-hee Cho ) 대한한방부인과학회 2016 大韓韓方婦人科學會誌 Vol.29 No.4

Objectives: The purpose of this study is to evaluate the effects of Korean traditional treatments for Climacteric Syndrome Patients with Hwa-Byung. Methods: From February 2015 to May 2015, We treated 5 Cases Patients with Korean traditional treatments for a month. We measured treatment effects by Menopause Rating Scale (MRS), Beck`s Depression Inventory (BDI), Visual Analogue Scale (VAS) and Digital Infrared Thermal Imaging (DITI). Results: After treatment, First, the scores of MRS, BDI were decreased. Second, the symptoms such as hot flush, pantalgia, palpitation, insomnia, fatigue were significantly improved. Also, the difference of ?中 (CV17, Danjung) and 關元 (CV4, Guanyuan) temperatures were significantly decreased after treatment. Conclusions: This study suggests that Korean traditional treatments such as Gamicheonglijagam-hwan, acupuncture, moxibustion are effective on Climacteric Syndrome Patients with Hwa-Byung.

청간소요산으로 호전된 설통 환자 3례

김연진,양승보,김정화,이상화,조승연,박성욱,박정미,고창남,Kim, Yeon-jin,Yang, Seung-bo,Kim, Jeong-hwa,Lee, Sang-hwa,Cho, Seung-yeon,Park, Seong-uk,Park, Jung-mi,Ko, Chang-nam 대한한방내과학회 2017 大韓韓方內科學會誌 Vol.38 No.4

Objectives: This clinical study reports the effects of Cheonggansoyo-san (CSS) on three patients with glossodynia. Methods: Three patients with glossodynia were treated with CSS (i.e., an herbal medicine) and acupuncture. Numeric rating scales (NRSs) for glossodynia and dry mouth and hwa-byung questionnaire scores were evaluated, and the results from heart rate variability (HRV) evaluations were analyzed. Results: After treatment with CSS, three patients' glossodynia symptoms, such as burning sensations, tingling, and numbness of the tongue, were improved. NRS ratings for glossodynia and dry mouth and the hwa-byung questionnaire scores also improved, and HRV parameters were closer to the normal range. Conclusion: Cheonggansoyo-san could be used to treat glossodynia.

Indomethacin-Ethylcellulose Microcapsules의 용출 특성에 관한 연구

이화정,구영순 梨花女子大學校 韓國生活科學硏究院 1992 韓國生活科學硏究院 論叢 Vol.50 No.-

Indomethacin-ethylcellulose microcapsules(IDM-MC) were prepared by solvent evaporation method using sod. lauryl sulfate(SLS) as a surfactant. In case of IDM-MC prepared with various ratios of ethylcellulose(EC) and polyethylene glycol 4000(PEG 4000) in 0.25% SLS solution, drug content of IDM-MC were 17.80% to 21.25%, while those of IDM-MC prepared using EC in various concentrations of SLS solution were 11.25% to 16.06%. Scanning Electron Microgram showed that the IDM-MC were almost spherical and had pores on the surface. Particle size distributions of IDM-MC were relatively regular. The dissolution rates of IDM from the IDM-MC retarded considerably compared with that of IDM powder ; the dissolution of IDM was more than 90% within 1 hour, but those of IDM from IDM-MC were about 20 to 70% within 24 hours. And, the dissolution of IDM from IDM-MC prepared with EC : PEG 4000=1 : 1 and stirred in 30(w/w)% glycerin solution was more twice than those of IDM from IDM-MC prepared without PEG 4000.

뇌척수액내의 결핵균 α- 및 β- 단백항원에 반응하는 항결핵균항체의 정량적 측정에 의한 결핵성 수막염의 진단적 접근

이경숙,백태현,김화중,박정규,최대경 충남대학교부설 생명공학연구소 1992 생물공학연구지 Vol.2 No.-

The aim of this study was to develop an immunologic method for the diagnosis of tuberculous meningitis with a sensitivity greater than that of the initial bacterial smear while maintaining good specificity. Purified α-antigen and β-antigen from unheated culture filtrate of Mycobacterium tuberculosis H37Rv was applied for its potential diagnostic utility in detection of IgG, IgM and IgA antibody in the cerebrospinal fluids of 14 patients with tuberculous meningitis and 27 non-tuberculous patients by ELISA at the CSF dilution of 1 : 5. The results were summarized as follows: 1. The mean ELISA values of IgG antibody activity to purified α-antigen in CSF of 14 patients with tuberculous meningitis and 27 controls were 0.769±0.638 and 0.090±0.068, respectively. The specificity and sensitivity were 96.3% and 92.9%. The mean ELISA values of IgG antibody activity to purified β-antigen were 0.668±0.507 and 0.092±0.070, respectively. The specificity and sensitivity were 92.6% and 92.9%. 2. The mean ELISA values of IgM antibody activity to purified α-antigen in CSF of 14 patients with tuberculous meningitis and 27 controls were 0.629±0.585 and 0.007±0.076, respectively. The specificity and sensitivity were 92.6% and 92.9%. The mean ELISA values of IgM antibody activity to purified β-antigen were 0.637±0.550 and -0.028±0.082. The specificity and sensitivity were 96.3% and 85.7%. 3. The mean ELISA values of IgA antibody activity to purified α-antigen in CSF of 14 patients with tuberculous meningitis and 27 controls were 0.266±0.330 and -0.22±0.032. The specificity and sensitivity were 96.3% and 85.7%. The mean ELISA values of IgA antibody activity to purified β-antigen were 0.031±0.419 and -0.048±0.037. The specificity and sensitivity were 96.3% and 85.7%. These results suggest that the purified α-and β-antigen are useful for the diagnosis of tuberculous meningitis.

한국의 기수련이 심장박동간격변화에 미치는 영향

이명수,허화정,김병기,류훈,정현택 한국정신과학학회 1998 韓國精神科學學會誌 Vol.2 No.2

심장박동간격은 최근 교감신경과 부교감신경의 안정을 알아보는 척도로 쓰이고 있다. 본 연구는 4~12개월 천도선법 기수련을 행한 20대의 20명의 기수련자와 동일 연령층의 20명의 일반인을 대상으로 하여 1시간 동안 천도선법을 수행하게 하여 전, 참선, 후의 심장박동을 생리 기록계로 측정을 하여 빠른 퓨리에 변환 (FFT)을 통하여 심장박동간격을 조사하였다. 그 결과 자율신경제의 안정척도인 저주파수 적분 값과 고주파수 적분 값의 비(LF/HF)가 수련전과 수련 중에서 천도선법 기수련생들의 값이 일반인과 비교하여 통계적으로 유의한 차이가 났으며 (p<0. 01) 특히 두 그룹 모두 HF 의 값이 유의하게 변화하는 것을 보았을 때 천도선법 기수련이 부교감신경의 활동을 조절하여 자율신경계를 안정화 시킨다는 것을 보여주었다. The effects of ChunDoSunBup (CDSB) Qi-training on the power spectrum of heart rate variability were studied in 20 healthy subjects and 20 CDSB Qi-trainee (subjects with CDSB Qi-training for 4-12 months) Continuous ECG signals were recorded during 1) 10 min of rest in sitting position, 2) 1 hour of CDSB Qi-training , 3) 10 min of post-training. Fast Fourier transformation was used to determine the power spectrum of heart rate variability While CDSB Qi-training, there were significant decrease in the ratio of low to high frequency power spectrum. And value of pre and mild-training in CDSB Qi-trainees were lower than that of control subjects There was a significant changes in high frequency power of both group, but net in low frequency These results suggest that CDSB Qi-training may stabilize autonomic nervous system by modulate parasympathetic nervous system.

독일형법에서의 양형규정에 관한 논의

이정원,이세화 慶南大學校 法學硏究所 2006 慶南法學 Vol.21 No.-