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김종해,이동헌,이철우,김중기,김동희,조규판 嶺南大學校 工業技術硏究所 1998 工業技術硏究所論文集 Vol.26 No.2
This paper proposes a double resonant high frequency inverter which reduces the distribution of the switching current. The analysis of the proposed circuit is generally described by using the normalized parameters. Also, the principle of the basic operation and the characteristics of driving were estimated by the switching frequency and the load parameters. And the data for the design were got by the characteristic values obtained from the characteristic estimation. At the same time the example of the design method was proposed. In addition, Comparing the theoretical waveforms to the experimental waveforms certified the operating characteristics of the proposed Inverter. It is certain that the proposed circuit will be used and expanded in the high frequency power supplies like induction heating systems.
알루미늄 합금과 고장력 강판 접합을 위한 헬리컬 SPR의 단조공정 설계
김원영, 김동범, 김기호, 김도훈, 이인환, 조해용 충북대학교 산업과학기술연구소 2013 산업과학기술연구 논문집 Vol.27 No.2
A self-piercing rivet(SPR) is a mechanical component for joining dissimilar materials. It is used for joining dissimilar material sheets such as aluminum alloy and steel. The self-piercing rivet directly pierces into sheets without drilling sheets beforehand unlike conventional rivets. However, the self-piercing rivet occurs buckling when piercing high strength steel. Therefore, a helical SPR which can pierce high strength steel sheet was designed. In this study, forging process was designed for manufacturing the helical SPR and simulated by using commercial FEM code DEFORM-3D. In the simulation of forging process for manufacturing rivet, process sequence, formability, forging load were investigated. The suitable forging process could be designed by comparisons of simulated results. Experimental trials have been carried out for same conditions as simulated ones. The simulated results agreed with the experimental ones. So, the analytic approach in this thesis is useful to save cost and time in the forging industry
임종한,장성실,김성아,문재동,채창호,홍윤철,김수영,김진석,김영욱,한상환,이혜숙,원종욱,송동빈,하은희,강성규 대한산업의학회 2001 대한직업환경의학회지 Vol.13 No.2
기존의 특수건강진단과 작업환경측정을 통한 직업병 관리가 진폐증, 소음성난청 등의 소수 특정질환에 국한되고 실제 직업병 발생 규모 파악이나 신종 직업병의 발견에 한계를 보인다는 사실은 산업의학전문가들 사이에서도 공감을 이루고 있다. 미국과 영국 등에서의 직업성질환 감시체계에 대한 경험은 우리 나라의 직업성질환 감시체계 구축에도 새로운 자극제가 되면서, 1998년이후 인천, 대전, 여천, 구미, 부울경 지역에서 지역 직업성질환감시체계를 산업보건관리의 중요한 시스템으로 구축하려는 노력이 확산되고 있다. 새로이 구축되어지는 이들 지역 직업성질환 감시체계는 감시하고자 하는 대상질환, 활용 가능한 인적자원 및 자료원, 지역 의료체계의 특수성 등에 따라서 목적과 방법을 달리하면서 독특한 형태로 발전을 하고 있다. 각 지역단위 감시체계들이 그 상황에 맞게 독특한 목적과 전략들을 발전 시키면서도, 향후 발전할 국가적인 차원의 직업성질환 감시체계 구축을 위하여 직업성질환 감시의 기본 전략 등을 공유하는 등의 노력이 필요하다. 환례 정의 및 기본적인 등록 서식의 공유, 직업성질환 감시 자료원의 발굴, 공동의 정보 네트워크 및 직업성질환 감시 데이터베이스 구축 등 직업성질환 감시활동을 지원하기 위한 여러 기초 인프라 구축에 힘을 모아야 할 것이다. 우리 나라에서 직업성질환 감시체계를 성공적으로 구축하기 위해서는 수집된 자료의 질 관리를 위한 직업성질환 감시의 원칙 제정과 감시 전략의 공유 등이 필요하며, 전국적인 직업성질환 감시체계의 하부구조라고 할 수 있는 지역감시체계의 기초 토대 마련과 강화작업이 절실하게 필요하다.
Lee, Dahae,Lee, Dong-Soo,Jung, Kiwon,Hwang, Gwi Seo,Lee, Hye Lim,Yamabe, Noriko,Lee, Hae-Jeong,Eom, Dae-Woon,Kim, Ki Hyun,Kang, Ki Sung The Korean Society of Ginseng 2018 Journal of Ginseng Research Vol.42 No.1
Background: The aim of the present study was to evaluate the potential protective effects of six ginsenosides (Rb1, Rb2, Rc, Rd, Rg1, and Rg3) isolated from Panax ginseng against tacrolimus (FK506)-induced apoptosis in renal proximal tubular LLC-PK1 cells. Methods: LLC-PK1 cells were treated with FK506 and ginsenosides, and cell viability was measured. Protein expressions of mitogen-activated protein kinases, caspase-3, and kidney injury molecule-1 (KIM-1) were evaluated by Western blotting analyses. The number of apoptotic cells was measured using an image-based cytometric assay. Results: Reduction in cell viability by $60{\mu}M$ FK506 was ameliorated significantly by cotreatment with ginsenosides Rg1 and Rb1. The phosphorylation of p38, extracellular signal-regulated kinases, and KIM-1, and cleavage of caspase-3, increased markedly in LLC-PK1 cells treated with FK506 and significantly decreased after cotreatment with ginsenoside Rb1. The number of apoptotic cells decreased by 6.0% after cotreatment with ginsenoside Rb1 ($10{\mu}M$ and $50{\mu}M$). Conclusion: The antiapoptotic effects of ginsenoside Rb1 on FK506-induced apoptosis were mediated by the inhibition of mitogen-activated protein kinases and caspase activation.
김명희,이영재,강훈이,강동수,김해섭,배태진 여수대학교 1998 論文集 Vol.13 No.2
To improve the utilization of sea tangle, the processing conditions of extracts, such as kind of additives, particle size of a sample, sample to solvent ratio, extracting temperature and time were studied. Among five extracting methods used for sea tangle extraction, the optimal method was water extraction. The most appropriate particle size of sea tangle powder, extracting temperature and mixing ratio of sea tangle to water were 5 mesh, 60℃ and 1 to 13(w/v), respectively. The basis of solids yield in sea tangle extract, optimal extracting time was about 2 hours. The yield of soluble solids under above-mentioned conditions was 5.1%.
골반 초음파 감시 하에 16 Gauge Angioneedle™을 사용하여 치료적 더글라스와 천자를 시행하여 치유된 복강 내 출혈 1예
김미영,이해혁,유애리,박정희,이임순,정수호,레앙소팔,배동한,김태희,이권해 순천향의학연구소 2008 Journal of Soonchunhyang Medical Science Vol.14 No.1
Culdocentesis is a procedure that checks for abnormal Quid in the space just behind the vagina (cul-de-sac). First, a pelvic examination is done. Then, after exposing the postehor vaginal fonix with a bivalve vaginal speculum the posterior lip of the cervix is grasped with a tenaculum. The cul-de-sac is then entered through the postehor vaginal wall with an 18-20 gauge needle with a syringe inserted. As the cul-de-sac is entered, suction is applied, and the intraperitoneal contents are aspirated. In the recent past, culdocentesis was commonly used in the evaluation of a vahety of common intraperitoneal conditions, principally, the hemorrhage associated with ectopic gestations and ruptured ovarian cysts the presence and/or drainage of purulent associated with pelvic inGammatory disease, and as a screening procedure to facilitate early diagnosis of ovarian neoplasms. Usually 16-18 gauge needle with a syhnge attached was used for culdocentesis. But we have experienced a case of therapeutic culdocentesis with 16 gauge angioneedle in patient of hemoperitoneum. So, report it with a bhef review of literature.
파밤나방(Spodoptera exigua (Hu¨bner))의 발육과 pterin 색소 함유량 변화
김해연,김동기,김용균 안동대학교 농업과학기술연구소 2000 農業科學技術 硏究論文集 Vol.7 No.-
곤충의 연령을 판정하는 것이 대상 곤충의 집단 동태 파악에 중요시 되어 왔다. 이를 위해서 최근에 질소화합물의 대사산물로서 pterin이 일부 곤충에서 발육기간과 밀접한 관련성이 있음을 나타냈고 이 물질의 함량이 개체의 연령 판정에 지표로 사용되고 있다. 본 연구는 파밤나방 (Spodoptera exigua(Hu¨bner))의 성충 머리에 pterin이 존재하는지 그리고 존재한다면 그 양이 파밤나방의 발육 기간과 관련이 있는 지가 분석되었다. 분광형광광도계를 이용하여 pterin 물질과 동일한 흡수파장과 형광파장을 보이는 물질이 파방나방 성충 머리 추출물에서 나타났다. 암수 모두에서 용기간 동안 발육온도가 갓 우화한 성충 머리의 pterin 함량에 영향을 주었으나, 각 온도에서 발육기간과 pterin 함량 사이에는 연관성이 없었다. 성충 발육에서 암수간, 나이별 및 발육온도에 따라 pterin의 함량은 차이 없이, 성충 한 마리당 11.2㎍의 pterin 함량을 유지했다. 이상의 결과는 파밤나방 성충머리에는 pterin 물질이 존재하지만, 이 물질의 함량이 용과 성충기간 중에는 발육기갈에 따라 차이가 없어 개체의 연령을 판정하는 데 지표로서 사용하기에는 곤란하다고 판정된다. The population age structure has been an important information to estimate and predict the population size of a specific insect pest. A recent age grading technique uses pterin content, as an age grading marker. Pterins are the metabolites of nitrogenous compounds and closely related with developmental periods in some insects. We had interests in the presence of pterin compounds in the beet armyworm, Spodoptera exigua(Hu¨bner), adults and in the relationship of the pterin contents and developmental period to use the pterin content for age grading marker. Spectrophotometry of the adult head extract showed the same chromatogram with an authentic pterin compound. Although pterin contents in the heads of the newly emerged adults were significantly different with pupal rearing temperatures in both sexes, there was no significant correlation between pterin contents and pupal developmental periods. In adult development, pterin contents were not so much different in rearing temperatures, sexes, and ages that they kept at 11.2㎍/individual through the whole adult period. These results indicate that pterin compound is accumulated in the adult head of S. exigua, but can not be used as an age grading marker because of lack of significant correlation between pterin contents and developmental period.