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송은석,이해혁,김태희,김정식,남계현,이권해,고은석 순천향의학연구소 2004 Journal of Soonchunhyang Medical Science Vol.10 No.2
Prolapse of the fallopian tube into the vaginal vault after hysterectomy is a rare complication. Since most of cases may resolve before detection or remain undiagnosed, the exact incidence is still unknown. Though most common sign of tubal prolapse is tender friable tissue in vaginal cuff, with the simptoms of lower abdominal pain, dysparenunia, vaginal discharge, or postcoital spotting. The definitive diagnosis should be confirmed histologically Recently, we experienced a case of fallopian tube prolapse after abdominal hysterectomy in a 41-year-old woman and report with a brief review of the literature.
조혈모세포이식 환자에서 침습성 진균 감염에 대한 Micafungin의 예방 효과 및 안전성
김시현,이동건,최수미,권재철,박선희,최정현,유진홍,이성은,조병식,김유진,이석,김희제,민창기,조석구,김동욱,이종욱,민우성,박종원 대한감염학회 2010 감염과 화학요법 Vol.42 No.3
Background: Micafungin, a potent inhibitor of 1,3-β-D-glucan synthase, is a novel antifungal agent of the echinocandin class. In vitro study showed that micafungin was effective against Aspergillus species as well as Candida species, but clinical data on the prophylactic efficacy against invasive fungal infections (IFIs) other than candidiasis are still lacking. Materials and Methods: We identified 60 consecutive adult hematopoietic stem cell transplantation (HSCT) recipients who received at least 3 doses of micafungin during neutropenic period. Micafungin was started as an alternative in patients who were intolerant or had adverse events (AEs) to primary prophylactic antifungal agents. We retrospectively reviewed the medical records and analyzed the efficacy and safety of micafungin for prophylaxis against IFIs. Results: The patients either had autologous (n=9) or allogeneic (n=51: 1 syngeneic, 24 sibling, 26 unrelated donor) HSCT. Itraconazole oral solution (n=58) was the most frequently used first line antifungal agent for prophylaxis and was administered for median 11 days. The most frequent cause of switch to micafungin was vomiting (n=42). The duration of neutropenia and micafungin administration was median 13 and 12 days, respectively. A successful outcome was achieved in 45 (75%) patients. Empirical antifungal therapy was initiated in 13 (22%) patients. There were 2 cases (3.3%) of breakthrough fungal infections which comprised a probable invasive pulmonary aspergillosis and a possible invasive fungal sinusitis. There was no case of invasive candidiasis. A total of 53 (88%) patients experienced at least one AE regardless of causality during micafungin administration. The most frequent AEs were hypokalemia, vomiting, diarrhea, and elevated serum aspartate aminotransferase or alanine aminotransferase. Among the aforementioned AEs, only 1 case of diarrhea could be classified as a probable relation with micafungin when causality was assessed. There was no AEs that caused discontinuation of micafungin. Conclusions: Micafungin seems to be a safe and effective agent for prophylaxis of IFIs including aspergillosis as well as candidiasis in HSCT recipients. However, further large, prospective, and randomized comparative studies are warranted for aspergillosis.
김희연,홍진환,박혜경,한상배,박종석,이은주,이정성,송경희,최은희,최영준,소경아,성영제,이주엽 식품의약품안전청 2000 식품의약품안전청 연보 Vol.4 No.-
본 연구는 분말상 원료(전분, 대두분)의 저장유통시 품질변화를 건전성과 안전성 측면에서 검토하여 식품의 기준 ·규격 설정f.」 합지적으로 반영하고자 하였다. 전분과 패두분의 이물을 검사하고, 2종 대두분(중국산, 미국산)을 ?0일간 IS'c와 30t에 저장하면서 성상, 수분, 산가, 과산화물가, 지방산 조성,아플라톡신 BB의 생성여부를 분석하였다. 중국산 대두분 30'』 저장군에서 50일 이후 곰팡이가 발생한 것 이외에 모든 시료에서 양호한 성상을 나타내었고, 전분과 대두닥 모든 시료에서 이물은 검출되지 않았다. 산가는 중국산과 미국산 시료간에 편차를 보여 증국산 30"C, 50일 저장시료에서 약 10배끙도 증가하였고, 과산화물가는 저장 90일후 15'E 저장군은 약 2.3배, 30'c 저장군은 3배정도 증가하였다. 대두분의 주요 지방산은 linoleic acidf18. 2), oleic acid(18 : 1), palmitic acid(16 : 0)이었으며, 3개월 저장에 따른 지방산 함량의 변화는 미미하였다. 아플라톡신 B₁은 모든 시료에서 검출되지 않았다. The objective of this study was to investigate auality changes of type raw materials(starch, soy flour) during various storage conditions. Starchflour(source of China, U.S.A) were slfred under two temperature(15'C, 30'c) forSensory evaluation, (o.reign material test, moisture content, acid value, peroxide ualue,composition, aflatorin Bi were analyzed. China soy flour(stor·ed 30'f) was contaminated by fungj on 50 days. Except for soy flour contardnated by fungi, sensory characteristics were not changed and foreign mater;als were notdetected. Acid value of China soy flour(stored at 30'C, 90 days) was about 10 times higherlevel before storage and acid value was more influenced by source(China, USA). Peroxide valuewas in proportion with the storage period slightly. The major fatty acid of soy flour waslinoleic acid(18 . 2), an(3 the change of fatty acid composition was not observed. Aflatoxlrl Blwas not detected.
횡문근융해증과 경한 신손상을 동반한 급성 A형 간염 1예
조규민,김창욱,성현진,허준,전부석,이종환,심은희,이석종,이창돈 영남대학교 의과대학 2012 Yeungnam University Journal of Medicine Vol.29 No.1
A 48-year-old male visited the emergency room of the authors’ hospital due to nausea, vomiting, and myalgia for four days. Acute hepatitis A was identified from the serologic marker of the hepatitis A virus. Mild elevation of the serum creatinine and creatinine phosphokinase(CPK) suggested rhabomyolysis, which was confirmed with the serum aldolase, myoglobin, and urine myoglobin. With supportive care, both the liver and renal func- tions were recovered gradually and fully. This case shows that rhabdomyolysis can be one of the mechanisms of renal complication in cases of acute symptomatic hepatitis A.
수중식물과 침전물에 의한 용존산소 변화량 결정 : 하천모델 이용법;a Stream Model Approach
이용석,최은주,박민대,박석순 江原大學校 附設 環境硏究所 1993 環境硏究 Vol.10 No.-
하천모델을 이용하여 한강 지류인 탄천에서 수초와 침전물에 의한 용존산소 변화량을 측정하였다. 수질자료에 따르면 탄천은 상류의 부영양화 지역 (Eutrophic Zone)과 하류의 강부수성 지역 (Polysaprobic Zone)으로 구분되며 상류는 수초의 광합성과 호흡이, 하류는 침전물 산소요구량이 수중 용존산소 농도 결정에 주 역할을 하고 있다. 하천조사는 1990년5월과 10월 2회에 걸쳐 2일간 연속적으로 실시되었다. 조사 결과 상류의 경우 수초 광합성과 호흡에 의한 매우 큰 용존산소 일주변화가 관찰되었다. 그러나 하류의 경우 침전물 산소요구량이 크고 수초 성장이 없기 때문에 일주변화가 거의 나타나지 않는 매우 낮은 농도가 측정되었다. 1차 조사시 상류에서 수중식물의 광합성량과 호흡양은 각각 55~100g 0₂/m²/day, 30~70g 0₂/m²/day으로 측정되었으며, 2차 조사시 각각 40~80g 0₂/m²/day, 25~55g 0₂/m²/day으로 측정되었다. 하류에서는 침전물 산소요구량이 1차 및 2차 조사시 동일하게 4~100g 0₂/m²/day로 측정되었다. The dissolved oxygen changes caused by aquatic plants and sediments were comput-ed in the Tancheon, a tributary of the HanRiver, by utilizing a stream model. According to the collected water quality conditions, the Tancheon was classified into two distinc-tive zones which were eutrophic zone in upstream area and polysaprobic zone in downstream area. The dissolved oxygen levels of the stream were determined mainly by the photosynthesis and respiration of the macrophytes in upstream area and by the sediment oxygen demand in downstream. Field data were obtained from two synoptic stream surveys performed during May and October, 1990 for two consecutive days The high diurnal dissolved oxygen variation was observed in upstream area due to an excessive growth of aquatic plants. In downstream area, however, little diurnal varia-tion with low dissolved oxygen level was observed, which would be attributed to high sediment oxygen demand and no discernible aquatic plant growth. In upstream area, the dissolved oxygen changes caused by the photosynthesis and respiration were ranged from 55g 100g 0₂/m²/day from 30 to 70 g 0₂/m²/day, respectively, during the first survey. The changes were ranged from 40 to 80g 0₂/m²/day for the photosynthesis and from 25 to 55g 0₂/m²/day for the respiration during the second survey, In downstream area, the sediment oxygen demands were measured from 4 to 100g o₂/m²/day during both surveys.
이강욱,전은석,박종훈,신영태,노흥규 충남대학교 의과대학 지역사회의학연구소 1993 충남의대잡지 Vol.20 No.2
In order to evaluate clinical utilities of Tc-99m MIBI dipyridamole stress myocardial SPECT in patients with coronary artery disease (CAD), we compaired tomographic and polar map images of Tc-99m MIBI myocardial SPECT with the results of coronary angiography in 25 patients with CAD (myocardial infarction 13,angina pectoris 12) in Chungnam National University Hospital from Oct. 1991 to Oct 1993. Percutaneous transcoronary angioplasty (PTCA) was done in three patients of 25 CAD patients and follow up SPECT studies were done in same three patients within 2 months after PTCA. The results were as follows : 1. Mean age of patients was 57.4 years. Man was 2.7 times more than woman. 2. Sensitivity and specificity of Tc-99m MIBI myocardial SPECT for the detection of coronary artery stenosis in patients with myocardial infarction were 92.7 % anf 85 %, respectively. 3. Sensitivity and specificity of Tc-99m MIBI myocardial SPECT for the detection of coronary artery stenosis in patients with angina pectoris were 100 % and 67 %, respectively. 4. After PTCA size of perfusion defects in stress SPELT images was decreased in all three patients . With the results above,we thought that Tc-99m MIBI myocardial SPECT is useful noninvasive method to detect stenosed coronary artery in patients with CAD and it can be used as a method to evaluate the result of PTCA.
이특구,권순정,오은진,김상길,김석준,김노석 한국의료복지시설학회 2006 의료·복지 건축 Vol.12 No.2
The purpose of this Guideline is to provide basic standardization basis for planning and designing of the dwellings so that elderly may live, either with their family or independently, an independently comfortable life style. Dwelling facility is defined as a physical area where important activities of daily life are conducted by a person/people and is also the focal place of a family. Therefore, the Guideline classifies the areas where daily activities are conducted by type of such activities and provides standards to countermeasure for natural physical disabilities of the elders.
이은석,嘉納成男 대한건축학회 2003 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.23 No.1
The purpose of this study is to analyze the actual conditions of the labour management is steel construction in Japan. The study has been performed by job site research and site observation. On this paper I studied the present situation in the job site and to propose man-hour conditions in steel construction. The result of this study are as follows: 1. About 20% of the whole-time working is consists of over-time working. 2. The working time of Erection & Fit-up bolting worker is changes by number of member rather than steel weight. 3. The working time of Final tightening worker is strongly relate with the number of final tightening bolts. This is the result of the stable working-posture and the standard procedure. 4. From 164 to 214 sets of final tightening bolts can be tighten by 8-hour working/day.