Alleviation of Hangover Effects by DA-5521: A Randomized, Double-blind, Placebo-Controlled, Crossover Trial

이설희,Sang-Pil Choi,Eun-Ock Park,정수진,Soo-Wan Chae,박영서 한국산업식품공학회 2024 산업 식품공학 Vol.28 No.1

Animal experiments have demonstrated the effectiveness of fermented rice germ and soybean extracts in lowering blood alcohol concentration. A compound primarily derived from fermented soybean extract constitutes the principal component of DA-5521, an experimental dietary substance examined in this study. We investigated the possible hangover-alleviating effects of DA-5521 in individuals aged 19 to 50 who had previously experienced hangovers. Moreover, we enrolled 22 participants who met the eligibility criteria and conducted a double-blind, randomized, placebo-controlled crossover trial. Six hours after alcohol consumption, the test group exhibited a statistically significant reduction in blood acetaldehyde concentration compared with the placebo group. Further, our results displayed significantly lower levels in the DA 5521 group at 0.50 and 0.75 h post-ingestion and substantially lower peak breath alcohol concentration compared to the placebo group. These findings confirm that consumption of DA-5521 can significantly ameliorate hangover symptoms by diminishing blood acetaldehyde concentration and reduce breath alcohol concentration.

에이즈 환자에서 발생한 파종성 조류형 결핵균 감염 1예

이설희,최재혁,최문한,신동원,최종효,김태형,전민혁,고은석,추은주 대한감염학회 2008 감염과 화학요법 Vol.40 No.5

Nontuberculous Mycobacteria, especially Mycobacterium avium complex (MAC) infection is a common opportunistic infection in patients with acquired immunodeficiency syndrome (AIDS). In patients with AIDS, MAC infection more frequently presents as disseminated form rather than localized infection. Disseminated MAC infection is associated with a high mortality rate in patient with AIDS. We report a case of disseminated MAC infection in an AIDS patient involving bone marrow, mediastinal lymph node and lung.

시각적 이미지를 촉각 이미지로 변환하기 위한 모델링 방법

이설희,김상연,서희석 한국지식정보기술학회 2011 한국지식정보기술학회 논문지 Vol.6 No.2

This paper presents the process that visual image translate to tactile image for blind people. People with visual disabilities through a computer or photo that has been implicated in a lot of information is difficult to acquire. In this study, for those who are visually impaired visual images into tactile images to model the process. Produced models photos, maps, mathematical formulas, such as the specific meaning of the visual image into a tactile image is a process and transmit information. If amount of information of visual image delivered to amouont of tactile user are confused. As a result, to convey the information that could be delivered to the wrong information. As the need for visual images to simplify the image by image processing due to a lot of information was chosen to reduce confusion. Models for different types of visual images as a result of the process through which it is appropriate to switch to the tactile image, the elements and the process can be predicted.

게임 장르의 유형화

이설희,권민석 한국게임학회 2008 한국게임학회 논문지 Vol.8 No.3

본 연구는 영화와 같은 다른 문화콘텐츠의 장르 구분을 수용하면서 애매하고 모호하게 지속되고 있는 게임 장르의 구분에 대한 새로운 시도이다. 게임 그 자체만을 대상으로 장르 구분을 할 경우 먼저 고려하게 되는 것은 게이머의 행위에 기반한 장르구분과 텍스트에 기반한 장르구분이 있을 수 있다. 연구 결과 게이머의 행위에 기반한 장르구분은 행위의 의미의 중복성과 이에 대한 객관적인 판단기준의 부재에 따라 그 한계를 드러낸다. 이에 반해서 상대적으로 객관적인 기준을 제시할 수 있는 게임 텍스트에 기반한 장르 구분은 3단계를 거쳐서 7개의 유형인 물리적 장애물 게임, 물리-인지적 장애물 게임, 인지적 장애물 게임, 인지-물리적 장애물 게임, 운용 게임, 대전 게임, 순위 게임으로 나뉘어진다. 그리고 각 유형의 게임들은 고유의 관습과 성격을 공유하고 있다. Classifying digital games' genres is quite ambiguous work, as they have been using other media's genre classification such as film genre. Therefore this paper tries to propose a new way of classifying genres of digital games. There are two kinds of approaches to digital games genres: one is based on gamers' activities and the other is on game text. The former turned out to be limitative because the meanings of gamers' activities are sometimes overlapped and this overlapping causes lack of objectivity in deciding which activity belongs to which genre. On the other hand, the latter is comparatively clear and accurate as it is based on what a game text provides. After all. a new classification of digital games based on game text makes total of 7 digital game types, which are Physical obstacles, Mainly Physical & partially intellectual obstacles, Intellectual obstacles, Mainly intellectual & partially physical obstacles, Self-supporting games, Confronting games, Ranking games, and each type has its own convention and characteristics.

입자 군집 최적화를 이용한 음악 데이터 특징 선택 및 음악 데이터와 관련된 감정 분류 실험

이설희,김해천,이재성 한국지능정보시스템학회 2018 한국지능정보시스템학회 학술대회논문집 Vol.2018 No.6

예비 특수교사의 수업역량 요소 도출 및 타당화

이설희,양한나,이가영 한국특수교육교과교육학회 2024 특수교육교과교육연구 Vol.17 No.1

본 연구의 목적은 예비 특수교사에게 요구되는 수업역량을 도출하여 타당화하는 데 있다. 이를 위해 선행문헌을 분석하여 특수교사의 수업역량 요소를 확인한 후, 현직 특수교사 14명을 대상으로 초점집단면담(FGI)을 실시하여 예비 특수교사에게 요구되는 수업역량을 추가적으로 도출하였다. 1차로 도출된 수업역량 요소의 내용 타당도를 확보하기 위해 특수교육 전문가 8명을 대상으로 설문조사를 실시하였으며, 최종 4개의 수업역량군과 19개의 수업역량 요소 및 구체적인 행동지표를 도출하였다. 위 연구결과를 바탕으로 일반교사와는 차별화되어 특수교사에게 요구되는 수업역량과 지능정보화사회로의 전환이 특수교사의 수업역량에 미친 영향 및 특수교육 교원 양성기관의 역할에 대해 시사하는 바를 논의하였다. The purpose of this study is to identify and validate the teaching competencies required for prospective special education teachers. To achieve this, the study began with an analysis of existing literature to identify the components of teaching competence for special education teachers, followed by conducting focus group interviews (FGI) with 14 current special education teachers to further identify the teaching competencies required for prospective special education teachers. To ensure the content validity of the initially identified teaching competencies, a survey was conducted among 8 special education experts, resulting in the final identification of 4 groups of teaching competencies, 19 elements of teaching competencies, and specific behavioral indicators. Based on the results of this study, the discussion includes the differentiated teaching competencies required for special education teachers compared to general teachers, the impact of the transition to an intelligent information society on the teaching competencies of special education teachers, and the implications for the role of special education teacher training institutions.

Rare Cutaneous Soft Tissue Sarcomas Treated With Slow Mohs Micrographic Surgery: Ten Years’ Experience at a Single Institution

이설희,정기양,최수이,Techapichetvanich Thanya 대한피부과학회 2024 Annals of Dermatology Vol.36 No.2

20대 게이들의 ‘데이팅앱’ 이용에 대한 연구

이설희,이예지 한국방송학회 2016 한국방송학회 학술대회 논문집 Vol.2016 No.04

고전압 펄스 전기장 처리에 의한 우유 단백질과 물리화학적 특성의 변화

이설희,김건,박영서 한국산업식품공학회 2013 산업 식품공학 Vol.17 No.3

Pulsed electronic field(PEF) 처리에 의한 우유 단백질과 물리화학적 특성의 변화를 확인하기 위하여 원유, 탈지유, HTST, LTLT, UHT 우유를 PEF 처리하였다. 시료 중의 단백질을 SDS-PAGE로 확인하였을 때, PEF 처리에 의한 우유 단백질의 변성은 관찰할 수 없었다. Differential scanning calorimetry(DSC)로 우유 단백질의 열변성 정점 온도(Td)를 분석한 결과, 탈지유를 65oC에서 PEF 처리하였을 때 Td가 87.66oC에서 97.18oC로 증가하여 PEF 처리가 우유 단백질의 변성에 영향을 미치는 것을 확인하였다. PEF 처리에 의한 alkaline phosphatase, protease, lactoperoxidase의 잔존효소활성을 측정한 결과, 원유와 탈지유에서 alkalinephosphatase는 PEF 처리에 의해 효소활성이 감소하였다. 또한 protease와 lactoperoxidase의 활성은 PEF 처리에 의해 영향을 받지 않았다. 65oC에서 PEF 처리한 원유는 처리하지 않은 원유보다 높은 갈색도를 나타내었으나, 기타 우유는 PEF에 의한 유의적인 차이가 없었다. 우유를 PEF 처리하였을 경우 산도의 변화는 관찰되지 않았고 pH의 경우에도 PEF 처리 여부에 따라 유의적인 차이는 있었으나 크게 변화하지는 않았다. Raw milk, skim milk, HTST-, LTLT-, and UHT-milk were treated with pulsed electric field (PEF) process and the changes in proteins and physicochemical properties of milk were examined. When protein profiles in samples were identified by SDS-PAGE, the denaturation of milk proteins by PEF treatment was not observed. When the denaturation temperature (Td) of milk proteins was analyzed with a differential scanning calorimetry (DSC), the Td of skim milk treated with PEF at 65oC increased from 87.66 to 97.18oC, which indicated that PEF treatment affected the denaturation of milk protein. The PEF treatment of raw milk and skim milk resulted in the decrease of alkaline phosphatase activity, whereas protease and

눈 메이크업의 실태와 선호색상에 관한 연구

이설희,김주덕 한국화장품미용학회 2018 한국화장품미용학회지 Vol.8 No.3

The eyes of the face can change their image through makeup, and can express various facial images and overall moods depending on the style of make-up. Therefore, the purpose of this study was to find a suitable image for me through eye makeup, not cosmetic surgery, considering the characteristics of each type of eye. First of all, 52.2 percent of women who do partially makeup showed significant differences in age and marriage, while 61.7 percent of women chose colors that suit them when purchasing eye shadows. Second, 61.7 percent of women who wear eye shadow "to make their eyes clear" accounted for the majority, while 41.9 percent of women used eye shadow for eye make-up, and 4.30 percent of women recognize that eye makeup affects their facial image. As is the case with this study, appearance plays a significant role in modern women, and the presence of the face suggests that the eye is recognized as an important factor that greatly influences the elements of self-image. Therefore, if eye makeup is done according to eye make-up, considering the characteristics of eye cosmetics and the image of color, the effects of eye makeup change will be higher if eye makeup.