http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
P-135 The Value of 18F-FDG PET/CT in evaluating disease severity in idiopathic pulmonary fibrosis
윤희영,고의원,이석현,하세진,류진숙,김동순,송진우 대한결핵 및 호흡기학회 2017 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.124 No.-
Objectives: Several biomarkers have been reported to be useful in assessing disease severity of idiopathic pulmonary fibrosis (IPF); however, the role of 18F-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG/PET-CT) is not well defined. The aim of study was to investigate the value of 18F-FDG PET/CT for assessing disease severity in IPF Methods: Clinical data were retrospectively reviewed in 89 IPF patients (mean age: 68.1 years, male: 94%) who performed 18F-FDG PET/CT for cancer evaluation at Asan Medical Center, Seoul. Standardized uptake value (SUV) was measured only in fibrotic area, and lesion-to-liver SUV ratio (SUVR) was also obtained. Correlation between 18F-FDG PET/CT parameters (SUV and SUVR) and clinical parameters including lung function, exercise capacity, and GAP index were analyzed. Results: Median follow-up period was 11.9 months and lung cancer was confirmed in 61 (69%) patients. SUV and SUVR were significantly correlated with forced vital capacity (r=-0.214, r=-0.275, respectively), diffusing capacity for carbon monoxide (r=-0.375, r=-0.373), distance (r=-0.297, r=-0.318) and the lowest oxygen saturation (r=-0.255, r=-0.339) during 6-minute walk test, and GAP index (r=0.343, r=0.321). SUV were also significantly correlated with decline in total lung capacity after 6 months (r=-0.501). SUVR was predictor for death (hazard ratio [HR]: 1.466; 95% confidential index: 1.009-2.131; p=0.045) on univariate analysis Conclusions: Our findings suggest that 18F-FDG PET/CT may be useful to assess disease severity in patients with IPF.
개인 창작자를 위한 국내 온라인 디자인 플랫폼 활용 방안
윤희영,하은아,조재경 한국인더스트리얼디자인학회 2017 산업디자인학연구 Vol.11 No.1
최근 온라인에는 네트워크 방식을 이용하여 자신의 창작물을 공유하고 거래하는 방식의 디자인 플랫폼이 나타나고 있다. 본 연구에서는 개인 창작자가 창작 의도에 맞는 플랫폼을 선택해 활용할 수 있도록 하고 제작한 창작물을 능동적으로 공유·거래 할 수 있는 지속가능한 플랫폼 활용 방안 제시하는 것을 연구 목적으로 하였다. 디자인 플랫폼은 기존의 웹 공유기반 플랫폼과 앞으로 성장 가능성을 염두 하여 모바일 전용 애플리케이션으로 나누어 분석하였다. 연구대상 선정은 ‘개인 창작자’, ‘핸드 메이드’, 등 주요 키워드를 중심으로 방문자 수와 데이터 보유량 및 활성도를 중심으로 대상을 선정하였고 다중명목척도를 사용한 SPSS통계프로그램의 오픈디자인 동질성 분석 키워드를 통하여 플랫폼 분석에 적용하였다 . 창작자는 다음과 같은 사항을 고려하여 온라인 디자인 플랫폼 활용해야 한다. 첫째, 개인 창작자는 온라인 디자인 플랫폼의 형태와 성격을 명확히 파악한 후에 목적에 맞는 플랫폼을 선택해야 한다. 둘째, 플랫폼 이용자와의 소통, 교류가 적극적으로 이루어지는 플랫폼을 선택해야 한며 셋째, 개인 창작자는 절차를 단순히 하는 편리한 UX 디자인 플랫폼을 선택해야 한다. 넷째, 개인 창작자는 부과 비용이 적은 플랫폼을 선택해야 하고 마지막으로 국내 온라인 디자인 플랫폼 활성화를 위하여 웹/앱 기반의 플랫폼은 형태에 관계없이 사회·문화적 현상으로서 디자인 플랫폼을 홍보하고 지속적인 노출을 해야 한다. 온라인 디자인 플랫폼을 통하여 창작물 거래의 활성화를 이루고 큰 시장을 형성하여 많은 디자인·공예 전공자들이 개인의 창의성을 발휘하기를 기대한다. Recently, online network system in the design of the trading system and to share their creations using the platform is emerging. In this study, individual creator suggest that those things into the creative platform to take advantage of actively sharing and the creation and production deals can do. To provide a sustainable platform, design platform sharing which is existed in both web based platform and exclusively for mobile applications in mind the possibility of analysis. Number of visitors and around main keywords such as selection ‘individual creator’, ‘hand-made’, studied data holdings and activity in the grand prize. Using the name selection program with multiple scales SPSS statistics were applied to this study. The creator should be considering these followings. First, the individual creator has to clearly define the form of purposes. Secondly, it should be an active communication platform. Third, design platform should be rather simple not complicated. Fourth, individual creator has to select low cost platform, and finally to boost the platform, the domestic online design platform should be based on the web and app. As social and cultural phenomenon, regardless of the type design platform for promoting continuous exposure to do.
윤희영,한혜주,이경미 한국마케팅학회 2020 마케팅연구 Vol.35 No.2
This research suggests that future anxiety heightens the perceived instrumental value of social relationships. As individuals feel more anxious about their future, their appreciation for the instrumental support from a relationship intensifies, and they are likely to show more positive attitudes toward an experience that provides an opportunity to meet new people. The current investigation is the first to show that people’s future anxiety can pull them together (rather than isolate them) by making people view social ties as a means of preparing for the future. Indeed, future anxiety is not only related to goal-directed behaviors, but also inevitably entails concerns about uncertainty and unpredictability regarding life events.
Cluster analysis reveals an exacerbator subtype among COPD patients
윤희영,이진화,이수환,김수정,류연주,장중현,이진국,유광하,정기석 대한결핵 및 호흡기학회 2018 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.126 No.0
Objectives: Acute exacerbation (AE) in patients with chronic obstructive pulmonary disease (COPD) is a poor prognostic factor and an important determinant of COPD therapy. We investigated the occurrence of AE according to COPD subtypes. Methods: Among COPD patients in Korea COPD Subgroup Study cohort, 1,195 patients who had follow-up data for AE were included in our study. We selected seven variables for clustering analysis - age, body mass index, smoking status, past history of asthma, COPD assessment test (CAT) score, post-bronchodilator (BD) forced expiratory volume in 1 second (FEV1) % predicted, and diffusing capacity of carbon monoxide % predicted. Results: K-means clustering identified four clusters: putative “asthma-COPD overlap (ACO)”, “mild COPD”, “moderate COPD”, and “severe COPD” subtypes. ACO group (n=196) showed the second-best post-BD FEV1 (75.5% vs. 80.9% [mild COPD, n=313] vs. 52.4% [moderate COPD, n=345] vs. 46.7% [severe COPD, n=341] predicted) and the lowest CAT score (12.2 vs. 13.7 vs. 15.6 vs 17.5) among four groups. Nonetheless, the ACO group had the greatest risk of the first AE compared to mild COPD group (hazard ratio [HR]: 1.766). The HRs of the moderate COPD group and the severe COPD group were 1.696 and 1.659, respectively. In addition, St. George’s Respiratory Questionnaire score (HR: 1.018) and gastroesophageal reflux disease were independent factors associated with the first AE (HR: 1.385). Conclusions: Like our ACO group, there are subtypes to be susceptible to AE, and these subtypes need more aggressive treatment strategies to prevent AE.