COVID-19로 인한 일개 대학 간호대학생의 비대면 수업 현황 및 만족도

성지현(Ji Hyun Sung) 고신대학교 전인간호과학연구소 2020 전인간호과학학술지 Vol.13 No.-

This study aims to investigate the satisfaction of students at a college of nursing to prepare and redesign nursing curriculum and pedagogical approach for rapidly changing educational environment under COVID-19. Methods: The study subjects consisted of 286 students at a college of nursing. The students were asked to complete the evaluation online survey for the satisfaction with the curriculum and educational environments under COVID-19. The evaluation survey of the untact education consisted of three parts: 1) environmental status of untact education; 2) satisfaction of untact education; 3) demands on untact education. Results: The mean score on the overall satisfaction level of untact educationa were 3.03±0.72. The highest rated items were achievement of learning objectives. However, intention of retaking classes online was low relatively. Moreover, the low rated items were policy of attendance, learner to learner interaction, and flow in learning. Conclusion: The findings of this study are timely important to redesign and prepare untact education under COVID-19. We need to try various strategies to improve the academic achievement and to successful adjust college life for nursing students under various environmental changes by redesigning a curriculum and renovating online educational platforms based on social change and student needs.

폐암 세포주에서 광역학 치료에 의한 유전자 발현 분석

성지현 ( Ji Hyun Sung ),이미은 ( Mi Eun Lee ),한선숙 ( Seon Sook Han ),이승준 ( Seung Joon Lee ),하권수 ( Kwon Soo Ha ),김우진 ( Woo Jin Kim ) 대한결핵 및 호흡기학회 2007 Tuberculosis and Respiratory Diseases Vol.63 No.1

연구배경: 광역학 치료는 폐암 치료에 실질적으로 이용 가능하며, 많은 연구들에서 폐암 세포에서 세포사멸을 일으킨다는 것이 이미 알려져 있다. 그러나 이 세포사멸의 기전은 아직 정확히 알려져 있지 않으며, 이에 암세포의 전사에서 초기 변화가 어떻게 일어나는 지를 알아보기 위하여 실험을 수행하였다. 방법: 광과민성 물질인 DH-I-180-3으로 A549 세포에 처리를 하고 광역학 치료를 한 후 관찰하였다. 광역학 치료 후 DEG kit를 이용하여 폐암 세포주에서의 유전자 발현을 보았으며, 유세포 분석기를 이용하여 세포 사멸을 측정하였다. 광역학 치료 후 의미있는 변화를 보인 유전자는 염기서열분석으로 확인하였다. 결과: 유세포분석 결과 폐암세포주는 대부분 세포괴사에 의하여 사멸되었다.광역학 치료 후, 9개의 유전자에서 명확한 변화가 있음을 발견했으며 이 중 8개의 유전자를 밝혀내었다. 3-phosphoglycerate dehydrogenase와 리보솜 단백질 S29의 유전자 발현이 증가되어 있었으며, carbonic anhydrase XII, clusterin, MRP3s1 protein, complement 3, membrane cofactor protein, β-1 integrin의 유전자 발현은 감소되어 있었다. 결론: 본 연구는 광과민성 물질인 DH-I-180-3을 이용한 광역학 치료에서 폐암 세포의 세포사멸의 주된 기전이 세포괴사에 의해 이루어 진 것임을 밝혀냈으며, 이와 관련된 유전자들 대부분이 막단백의 변화를 통해 이루어짐을 알 수 있었다. Background: Photodynamic therapy is a viable option for lung cancer treatment, and many studies have shown that it is capable of inducing cell death in lung cancer cells. However, the precise mechanism of this cell death has not been fully elucidated. To investigate the early changes in cancer cell transcription, we treated A549 cells with the photosensitizer DH-I-180-3 and then we illuminated the cells. Methods: We investigated the gene expression profiles of the the A549 lung cancer cell line, using a DEG kit, following photodynamic therapy and we evaluated the cell viability by performing flow cytometry. We identified the genes that were significantly changed following photodynamic therapy by performing DNA sequencing. Results: The FACS data showed that the cell death of the lung cancer cells was mainly caused by necrosis. We found nine genes that were significantly changed and we identified eight of these genes. We evaluated the expression of two genes, 3-phosphoglycerate dehydrogenase and ribosomal protein S29. The expressed level of carbonic anhydrase XII, clusterin, MRP3s1 protein, complement 3, membrane cofactor protein and integrin beta 1 were decreased. Conclusion: Many of the gene products are membrane-associated proteins. The main mechanism of photodynamic therapy with using the photosensitizing agent DH-I-180-3 appears to be necrosis and this may be associated with the altered production of membrane proteins. (Tuberc Respir Dis 2007; 63: 52-58)

건강성인에서 MDR1의 유전자 다형성에 따른 심바스타틴의 대사의 차이

성지현 ( Ji Hyun Sung ),한선숙 ( Seon Sook Han ),이미은 ( Mi Eun Lee ),하권수 ( Kwon Soo Ha ),김우진 ( Woo Jin Kim ) 대한내과학회 2009 대한내과학회지 Vol.77 No.2

Background/Aims: Simvastatin has dramatically reduced cardiovascular disease due to elevated cholesterol. The human multidrug resistance 1 gene (MDR1) encodes a 170-kDa transmembrane glycoprotein (P-glycoprotein), which plays an important role in regulating the absorption, distribution, and excretion of simvastatin. To clarify the effects of the MDR1 gene polymorphism on simvastatin pharmacokinetics, we investigated whether there is an association between genotype and the pharmacokinetic parameters for simvastatin. Methods: Thirty-one healthy unrelated Korean volunteers were genotyped for MDR1. Genomic DNA from blood was analyzed using the polymerase chain reaction (PCR) and restriction fragment length polymorphism (RFLP). Following an overnight fast, all of the subjects took a single 60-mg oral dose of simvastatin. Venous blood samples were taken for 12 hours after the oral drug intake. A statistical analysis of the MDR1 genotype and pharmacokinetic parameters of simvastatin was performed. Results: The mean Tmax of the 1236TT genotype was significantly higher than that of CT and CC (p=0.02). The mean AUC0-12h of 3435TT was also significantly higher, compared with CT and CC (p=0.01). No significant difference was observed between the MDR1 single nucleotide polymorphism (SNP) for G2677A/T and the pharmacokinetic parameters. Conclusions: These findings suggest that polymorphic MDR1 genes are important in the inter-individual variation of the disposition of simvastatin in humans. (Korean J 77:211-217, 2009)

카지노 종사원의 경력정체 지각이 이직의도에 미치는 영향

성지현(Sung, Ji-Hyun) 한국서비스산업학회 2012 서비스산업연구 Vol.9 No.2

判断表現「-と見る」と「-고 보다」に関する日·韓対照研究 ― 判断主体に注目して ―

成知炫 ( Sung Ji-hyun ) 한국일어교육학회 2022 일본어교육연구 Vol.- No.59

本稿では、日本語の判断表現「-と見る」とその韓国語に当たる「-고 보다」について、誰の判断を表すかという判断主体に注目して、「-と見る」文と「-고 보다」文の主語の人称を比較し、それぞれの語彙的特徴を明らかにした。 「-と見る」の判断主体については、富坂(1999)に新聞テキストにおいて組織や組織の一員が多いという指摘があったが、実際にどのようなものが現れているか明らかでなかった。本稿では、新聞と文学というテキストの違いを考慮しながら実証的に調査した。その結果、「-と見る」は三人称主語の文に極めて多く現れ(95.3%)、「-고 보다」は一人称に最も多く現れている(62.2%)ことを指摘した。 また、三人称主語において、「-と見る」と「-고 보다」ともに組織、組織の一員、専門家、多数の人の例が共通して現れ、多くを占めている。しかし、「-と見る」の新聞テキストでは、組織の例が一番多く(55.2%)、捜査機関の例が多いことに比べ、「-고 보다」の新聞テキストの場合、新聞全体で組織の占める割合が高くない(19.2%)ことと、非捜査機関の例が多いことを違いとして指摘した。文学テキストでも、「-と見る」は歴史小説に多く現れ、歴史的な人物の判断が「-と見る」で示されていることが多いが、「-고 보다」では一個人の例が多いことを明らかにした。 一人称主語においては、「-と見る」の場合、全体の例が少なく、文学テキストでの一個人の例も2例にとどまっている。一方、「-고 보다」の場合、一人称主語の用例が最も多い。新聞テキストでは、社説、コラム、オピニオンに多く、文学テキストでは一個人の例が一番多い。二人称主語においては、「-と見る」の場合、用例がほとんどなく、まともな二人称主語の文ではないことに比べ、「-고 보다」の場合、新聞のインタビューや対談の会話文に現れ、まともな二人称主語の文であることを指摘した。 In this paper, the judgment expressions ‘to-miru’ and ‘ko-poda’ were considered, focusing on the subject of judgment. First, by examining whether the subject of judgment is the speaker (author), the listener (reader), or the third person, ‘to-miru’ appears frequently in the sentences of the third person subject(95.3%), and ‘ko-poda’ is the most common in the first person subject(62.2%). Second, considering the difference between the texts of newspapers and literature, this paper pointed out the lexical characteristics of subjects that appear frequently in each person. In the third person subject, both ‘to-miru’ and ‘ko-poda’ have common examples of organizations, members of organizations, experts, and many people, and occupy most of them. In the text of newspaper of ‘to-miru’, the number of organizations is the largest(55.2%), and among them, there are many investigative agencies. On the other hand, ‘ko-poda’ does not account for a large proportion of the newspaper text(19.2%), and among them, there are many examples of non-investigative agencies as a difference. Even in literary texts, ‘to-miru’ often appears in historical novels, and the judgment of historical figures is often indicated by ‘to-miru’, but in ‘ko-poda’ there are many examples of one individual. Also, in the first person subject, ‘to-miru’ has few examples as a whole, and in literature one individual’s examples are only two. But ‘ko-poda’ has the most examples, especially in editorials, colums, and opinions of newspaper. In literary texts, there are many examples of one individual. In the second person subject, ‘to-miru’ has few examples and is not decent sentence, whereas ‘ko-poda’ appears in newspaper interviews and dialogues, and is decent.

간호대학생의 성평등의식, 진로정체감, 의사소통능력이 대학생활적응에 미치는 영향

성지현(Ji Hyun Sung) 한국자료분석학회 2020 Journal of the Korean Data Analysis Society Vol.22 No.6

본 연구는 간호대학생의 성평등의식, 진로정체감, 의사소통능력이 대학생활적응에 미치는 영향을 확인함으로써 간호대학생의 대학생활적응 향상을 도모할 수 있는 기초자료를 제시하고자 수행되었다. 자료수집은 2019년 9월 20일- 10월 14까지 B시 소재 간호대학생 151명을 대상으로 구조화된 설문지를 이용하여 진행하였다. 수집된 자료는 SPSS 25.0 프로그램을 이용하여 서술통계, t-검정, ANOVA 및 Scheffé test, Pearson s 상관계수(correlation coefficients), 다중회귀분석 방법으로 분석하였다. 연구결과, 간호대학생의 대학생활적응은 종교 유무, 입학 동기에 따라 유의한 차이를 보였으며, 진로정체감(r=.643, p<.001), 의사소통능력(r=.605, p<.001) 간에 유의한 양의 상관관계를 나타냈다. 대학생활적응에 영향을 미치는 요인은 의사소통능력 (β=.482, p<.001), 진로정체감(β=.410, p<.001)으로 나타났다. 이 변인들의 대학생활적응에 대한 총 설명력은 56.7%였으며 의사소통능력이 가장 주된 영향요인임이 확인되었다. 따라서 간호대학생의 대학생활적응 향상을 위해 간호교육과정에 의사소통능력 및 진로정체감 증진을 위한 교과 또는 비교과프로그램을 개발하고, 적용하는 노력 및 그 효과를 검증하는 후속 연구가 더욱 활발하게 이루어져야 할 것이다. The aim of this study is to identify the influence of gender equality, vocational identity, and global interpersonal communication competence (GICC) on college life adjustment of nursing students. Data collection was conducted with 151 junior and senior nursing students using structured self-reported questionnaires during September to October, 2019. Data were analyzed using descriptive statistics, independent t-test, one-way ANOVA, Scheffé test, Pearson correlation coefficient, and stepwise multiple regression analysis using SPSS 25.0. College life adjustment level of the participants showed statistical differences according to religion, reasons for applying in nursing school. There was a positive correlation between vocational identity, GICC and college life adjustment. The significant predictors of college life adjustment were GICC and vocational identity. These variables explained 56.7% of the variance in college life adjustment. The findings show that development and application of educational programs or extracurricular programs to enhance communication skills and vocational identity are crucial for improving college life adjustment in nursing students. Moreover, it is needed to examine the effect of these program in further study.

의도를 나타내는 보조동사「~てやる」의 한·일대조연구

성지현 ( Sung Ji Hyun ) 한국일어일문학회 2018 日語日文學硏究 Vol.106 No.1

본 연구는 「~てやる」가 은혜, 불이익, 강한 의지라는 의지용법으로 쓰일 때, 각각에 대응하는 한국어 형식을 고찰한 것이다.종래의 연구에서는「~てやる」가 은혜 및 불이익의 용법에서는 「~てやる」가 「-어주다」에 대응하고, 강한 의지의 용법에서는 대응하지 않는다는 지적에 머물러 있었다. 본 연구에서는 은혜, 불이익, 강한 의지 각각이 실제로 어떠한 형식에 대응하는 지에 대하여, 「~てやる」가 회화문에서 쓰일 때와 내적발화 및 혼잣말로 쓰일 때를 구분하여 고찰한 결과 아래와 같은 내용이 밝혀졌다.은혜 용법에 대응하는 한국어는「-어주지」가 가장 많았으며, 「-어주지」및「-어줄테니」「-어줄게」「-어주마」가 은혜 용법의 절반 정도(46.3%)를 차지하고 있었다. 「-어주다」에 대응하지 않는 형식으로는「-겠-」이 가장 많이 나타나 있었다.불이익 용법에 대응하는 한국어는「-어주겠다」가 가장 많았으며, 「-어주지」「-어줄테니」「-어주마」등이 나타나 있었다. 그러나, 은혜의 용법에서 많은 비중을 차지했던 「-어줄게」는 나타나 있지 않았다. 이에 대해 「-ㄹ게」가 청자에게 이로운 사실을 약속하는 기능이 있기 때문임을 설명하였다. 「-어주다」에 대응하지 않는 형식으로는 「-ㄹ것이다」가 가장 많았다.강한 의지 용법에 대응하는 한국어는「-ㄹ거야」「-겠-」등이 나타나 있었다. 또한, 종래의 연구에서는 강한 의지용법의 경우 「~てやる」가 「-어주다」에 대응하지 않는다고 지적 되어왔으나, 독백이나 혼잣말에서 사용되는 「~てやる」중에서「-어주다」에 대응하는 예(「-어주지」「-어주겠다」)가 있음을 실제 용례를 통해 제시하였다. This study examines the Korean form corresponding to “te-yaru,” which appears in the sentences implying the speaker’s offering, warning, or strong intention. Previous researches have focused only on whether or not “te-yaru” corresponds to “eo-juda.” In this study, by analyzing extensive corpus from novels, essays, and dramas and by separating the usage in monologue from that in dialogue, we extend the previous researches and show the followings.First, we show that in the sentence implying the speaker’s offering “te-yaru” corresponds to “eo-juji,” “eo-julteni,” “eo-julge,” “eo-juma,” in half of the cases we analyzed. The sentences in which “te-yaru” corresponds to “eo-juji” appeared most frequently.Second, we show that in the sentence implying the speaker’s warning “te-yaru” is not translated to “eo-julge,” which appears frequently in the sentences implying the speaker’s offering. In such sentences, “eo-jugetta” and “eul-ge” are chosen for “te-yaru.”Last, previous studies have shown that “te-yaru” does not correspond to “eo-juda,” when it means strong will. However, we show that several counterexamples when “te-yaru” is used in monologues.

스텍앙상블과 인접 넷플로우를 활용한 침입 탐지 시스템

성지현(Ji-Hyun Sung),이권용(Kwon-Yong Lee),이상원(Sang-Won Lee),석민재(Min-Jae Seok),김세린(Se-Rin Kim),조학수(Harksu Cho) 한국정보보호학회 2023 정보보호학회논문지 Vol.33 No.6

意志表現に関する韓·日対照研究 ― 「つもりだ」を中心に ―

成知炫 ( Sung¸ Ji-hyun ) 한국일어교육학회 2021 일본어교육연구 Vol.- No.56

本稿では、第三者の意志が捉えられるという「つもりだ」の特徴に着目し、「つもりだ」文を人称別に分けて、三人称者の意志が現れている文を一人称者の意志の文や二人称者の意志の文と比較し、その文法的特徴を考察した。また、「つもりだ」の韓国語の対応形式の1つである「작정이다」を同じ方法で考察し、両形式の類似点と相違点として次のことを明らかにした。 まず、「つもりだ」と「작정이다」ともに、三人称者の意志の文と一人称者の意志の文が多く、二人称者の意志の文がそれより少ないことを類似点として指摘した。また、この結果から両形式が第三者の意志を捉える重要な形式であることを主張した。また、「つもりだ」と「작정이다」ともに二人称者の意志の文で皮肉や避難の意味が表れることを指摘した。 次に、「つもりだ」と「작정이다」の両形式ともに否定形が使われることを類似点として指摘し、相違点についても明らかにした。すなわち、「つもりだ」の場合、否定表現の66例のうち、「つもりはない」のように「意志の存在を否定する」後方否定(57例、86.4%)が「しないつもりだ」のように否定的な意志を表す前方否定(9例、13.6%)より非常に多い。一方、「작정이다」は、否定表現の28例のうち「작정이 없다」のような後方否定は4例(14.3%)しかなく、「-지 않을 작정이다」のような前方否定(24例、85.7%)のほうが多いことを明らかにした。 This paper focuses on the feature that “tsumorida” is a form that can express the will of a third person. “Tsumorida” is divided into a first person sentence, a second person sentence, and a third person sentence, and these characteristics are considered. In addition, this paper examines “jakjungida”, which is one of the Korean corresponding formats of “tsumorida”, and clarifies the following similarities and differences between the two formats. First, We pointed out that both “tsumorida” and “jakjungida” have many sentences of the will of the 3rd person subject and the will of the 1st person subject, and fewer sentences of the will of the 2nd person subject. Also, this reveals that both forms are not just forms that can express the will of a third person, but are important forms that express the will of a third party. We also pointed out that both “tsumorida” and “jakjungida” show the meaning of irony and criticism in the sentences of the will of the 2nd person subject. In addition, the fact that both “tsumorida” and “jakjungida” have negative forms was pointed out as similarities, and the following facts were revealed as differences. Specifically, “tsumorida” has many backward negations that deny the existence of the will, such as “tsumoriwa-nai” and “jakjungida” has many forward negations, such as “hajianul-jakjungida”.

DWT기반의 Human Visual System을 이용한 ROI 워터마킹 기법

성지현(Ji-Hyun Sung),홍충선(Choong-Seon Hong),이대영(Dae-Young Lee),황재호(Jae-Ho Hwang) 한국통신학회 2002 한국통신학회 학술대회논문집 Vol.2002 No.11