고콜레스테롤혈증 환자의 식이 섭취 양상

박혜순,신은수,김숙영 한국지질학회 1993 韓國脂質學會誌 Vol.3 No.2

Hypercholesterolemia is recognized as a major risk factor of atherosclerosis and coronary heart disease. Recently, as dietary pattern in Korea is changed to Westernized dietary pattern, so the concentration of serum cholesterol is being observed higher than the past. The purpose of this study is to investigate the difference of dietary pattern between hypercholesterolemia and control group in Korea. We gathered case group among persons who had been verified hypercholesterolemia and control group among persons who had taken medical examination in Asan Medical Center. The results are as follows; 1) The hypercholesterolemia group and control group consist of 78 and 140 cases, respectively. 2) The differences of smoking and alcohol histories between two groups were not significant. The number of cases of participating regular exercise in male hypercholesterolemia group is significantly less than the control group, but not in female case. 3) The body weight, relative body weight, and body mass index in male hypercholesterolemia group were significantly greater than those in control group, but not in female case. 4) The total cholesterol, LDL-C and TC/HDL-C in hypercholesterolemia group were significantly greater than control group. The difference of HDL-C between two groups was not significant. The triglyceride in male hypercholesterolemia group was significantly greater than control group, but not in female case. 5) The cholesterol intake in male and premenopausal female hypercholesterolemia group was greater than that in control group, but not in postmenopausal female case. The differences of intake in total energy, carbohydrate, fat, protein, fiber, animal fat, vegetable fat, animal protein and soy protein between two groups were not significant.

비만 환자에서 메실산시부트라민의 유효성 및 안전성 평가를 위한 염산시부트라민과의 이중맹검, 무작위배정, 다기관 공동, 비교 임상시험

박혜순,김경수,김범택,이관우,최웅환,안철우 대한비만학회 2008 The Korean journal of obesity Vol.17 No.2

연구 배경 : 비만치료제 중 시부트라민은 중추적으로 작용하여 신경 말단에서 주로 serotonin(5-HT)과 noradrenaline(NA)의 재흡수를 억제하며 SNRI (serotonergic and noradrenergic reuptake inhibitor)로 포만감을 항진시키고 식욕을 저하시킨다. 국내에 메실산시부트라민이 개발되어 12주 투약 후 효능과 안전성에 대해 기존의 염산시부트라민과 비교하고자 하였다. 방법 : 만 18세 이상 65세 이하의 성인 중 체질량지수가 30 kg/m2 이상 이거나 27~29.9 kg/m2이면서 고혈압, 당뇨병, 고지혈증 등의 위험인자를 가지고 있는 비만 환자를 대상으로 하였다. 총 275명의 피험자가 스크리닝에 참여하였고 부적합한 57명을 제외하고 218명(남 94명, 여 124명)이 무작위 배정되었다. 무작위 배정 후 시험군에는 메실산시부트라민 11.5 mg, 대조군에는 염산시부트라민 10 mg 투약하였고, 4주 후 투약 전 측정한 체중에 비하여 2 kg 이상 감소한 피험자는 같은 용량을 12주까지 투약하였으며, 2 kg 미만 감소한 피험자는 메실산시부트라민을 17.3 mg, 염산시부트라민을 15 mg으로 각각 증량하여 12주까지 투약하였다. 결과 : 일차 유효성 평가변수를 기존 체중에 비해 5%이상 감소한 피험자의 비율로 정하였을 때 ITT 분석시 시험군에서 55.8%, 대조군에서 53.5%으로 두 군간 유의한 차이는 없었다. 4, 8, 12 주에 측정한 체중 및 허리둘레 변화에서 두 군간 유의한 차이는 없었고, 12주 후에 측정한 체지방 및 혈중 지질치 변화도 두 군간 차이는 나타나지 않았다. 안전성 평가에서는 시험약과의 관련성을 배제할 수 없는 이상반응이 시험군 55건, 대조군 59건으로 유사하게 발현되었으며 이상반응으로 투약을 중단한 피험자는 시험군이 2명, 대조군 6명이었다. 결론 : 메실산시부트라민의12주 투약 후 효능과 안전성에 대해 염산시부트라민과 비교한 결과, 5% 이상 체중감소 환자의 비율이 시험군에서 55.8%, 대조군에서 53.5%으로 유의한 차이가 없었으며, 체중, 허리둘레 및 체지방 감소와 혈청 지질 변화에 두 군간 유의한 차이가 없었고 부작용 빈도도 유사하였다.

삶의 태도변화 : 소유론에서 존재론으로

박혜순 서강대학교 생명문화연구원 2013 생명연구 Vol.30 No.-

오늘날 우리는 존재론적 위기에 처해 생명이 좌초되는 현상을 자주 목격하게 된다. 사회적 경쟁구조가 충돌의 위험을 수반하고 있고, 그 과정에서 굶어죽는 사람도 발생하고 자살하는 사람도 늘어나고 있다. 이런 상황이 계속되게 할 수는 없으므로 변화가 필요하다. 철학이 그 기반을 마련해 주어야 하는데 변화의 시도는 인간의 실존양식에서 시작되어야 한다고 생각한다. 우들 대부분의 실존양식은 소유론적이다. 내가 보기에 소유론적 실존양식은 생명력 고갈과 관계되고 존재론적 실존양식은 생명력 고양과 관계된다. 더욱더 중요한 것은 우리의 실존양식이 미래세대의 존속문제와 긴밀한 관련을 맺고 있다는 사실이다. 이에 이 글에서는 인간이 존재론적 실존양식으로 전환해야 하는 이유를 노자와 「계사전」 그리고 『태일생수를 전거로 삼아 전개했다. 노자의 유무상생, 「계사전」의 음양의 법칙, 『태일생수』의 일결일영의 법칙은 우리가 존재법칙의 반쪽만 실현하고 있다는 사실을 알게 해준다. 소유론적 실존양식은 우리 스스로 관계적 맥락을 파괴하고 존재기반을 무너뜨리는 방식이다. 그것은 또 이 세계에서 ‘생성 변화의 물결’이 제대로 작동하지 못하게 함으로써 생명위기를 야기하는 주된 원인이다. 따라서 해법은 우리의 실존양식의 변화에서 찾아야 할 것이라고 생각한다. In today’s world, the phenomenon of stranded life caused from ontological crisis is frequently observed. Our social structure of competition brings about catastrophic results; such as increasing the number of people who die from hunger and by suicide. This situation cannot be tolerated. Change is needed. Philosophy should play a foundational role in initiating such a change. The attempt of change must begin from humans’ modes of existence. What is taken by majority of people today is possessive mode of existence, which is correlated to depletion of life. On the other hand, ontological mode of existence is correlated to vitality of life. What is important to point out in this context is that our mode of existence is interrelated to existential problem of future generation. This implies that future continuation is dependent on our modes of existence. In this article, I am going to argue that we should move on to ontological mode of existence from possessive mode of existence. This argument will be supported by the water’s mode of existence in three classical pieces of Lao-tzu, ‘the Commentary on the Apprehended Phrases’ and ‘The Great One Gave Birth to Water’. Lao-tzu’s ‘being and non-being beget each other’, The principles of Yin and Yang of ‘the Commentary on the Appended Phrases’ and “‘the principles of filling and clearance’ of ‘The Great One Gave Birth to Water’” provoke us to realise that we are pursuing only half of the modes of existence. Possessive mode of existence is a trivial manner that ruins our relational context and existential foundations on our own. It is also the main cause of life crisis as it would not allow ‘wave of change generation’ to operate properly.

생태적 감응력을 위한 공부론 - 치양지

박혜순 한국양명학회 2005 陽明學 Vol.0 No.14

초음파로 진단된 지방간의 임상적 고찰

박혜순,김영식 대한가정의학회 1990 Korean Journal of Family Medicine Vol.11 No.9

비만 환자에서 행동,식사,운동 교육을 통한 체중 조절

박혜순,정영순,신은수,김명화,김철준 대한가정의학회 1993 Korean Journal of Family Medicine Vol.14 No.4

고중성지방혈증 환자에서의 식이요법에 대한 효과

박혜순,신은수,김재중 한국지질학회 1995 韓國脂質學會誌 Vol.5 No.1

Hypertriglyceridemia increase in Korea recent years. Although diet therapy is the standard initial treatment for hypertriglyceridemia, the effect of diet therapy have not been investigated. This study was designed to evaluate the effect of diet therapy for hypemiglyceridemia. Forty outpatients with hypertriglyceridemia were educated for individualized diet therapy to decrease semen hypertriglyceridemia level. After three and six months, we assessed the changes of plasma lipids, apolipoproteins, and body weight. After 3 months of the diet therapy, there were significant reductions in triglyceride and VLDL-C(-15.7% in male, -39.4% in female). After 6 months of the diet therapy, there were significant reductions in triglyceride and VLDL-C(-30.4% in male, -32.5% in female). Diet therapy in hypemiglyceridemic patients is effective for reductions of triglyceride and VLDL-C.

일부 도시지역 여대생들의 신체상과 섭식 장애 및 영양 섭취 양상

박혜순,이현옥,승정자 대한지역사회영양학회 1997 대한지역사회영양학회지 Vol.2 No.4

Concern about body weight among young females is too much, so distorted body image and restrained eating are serious problems among Korean young females. A society preoccupied with thinness give a psychological burden to women, this burden may have adverse effects on health physically and psychologically. We tried this study to investigate body image, eating problems, and dietary intakes among female college students in urban areas of Korea. We satisfactorily surveyed using their body weight, desired weight dieting, binge eating, and night eating by self-questionnaires with 500 female college students. We evaluated their dietary intakes by semi-quantitative food frequency questionnaires to assess their usual intakes. After removing incomplete data, we analyzed 469 data by SAS 6.10. The 469 women aged 21.1 years. Their mean height, weight, and BMI were 161.4cm, 52.5kg, and 20.2kg/$m^2$ respectively. Though the frequency of obesity was only 2.6$\%$, the frequency of dissatisfaction with their body weight was 84.7$\%$. Female college students desired their hight, weight, and BMI to be 165.8cm, 48.2kg, and 17.5kg/$m^2$, respectively. The frequency of binge eating and night eating were 20.7$\%$and 6.8$\%$. The odds ratios for binge eating and night eating were 10.9(95$\%$ CI : 2.6-15.1) and 6.0(95% CI : 1.8-14.8) in the group satisfied with their body weight compared with the dissatisfied group. The odds ratios for binge eating and night eating were 2.6(95% CI : 1.6-4.4) and 2.4(95% CI : 1.1-5.4) in the dieting group compared with the non-dieting group. The mean caloric intake was 1, 840kacl and percent intakes of carbohydrate, protein, and fat wee 57.2$\%$, 16.3$\%$, and 24.0$\%$, respectively. The dieting group showed deficient intakes of protein and calcium significantly compared with the non-dieting group showed deficient intakes of protein and calcium significantly compared with the non-dieting group. Almost all women college students in urban area had dissatisfaction with their body shape, and desired severe undrerweight. The frequency of binge eating and night eating increased according to dissatisfaction with body weight, diet, and distortion of body image. Dieting has adverse effect on the intakes of essential nutrients. Educations is needed to correct distorted body image, and bad eating habits in young females, and marked preoccupation with thinness among women should then be reduced. (Korean J Community Nutrition2(4) : 505-514, 1997)

한국인 고콜레스테롤혈증 환자에서의 식이요법의 효과

박혜순,신은수,김재중,이종구 대한순환기학회 1994 Korean Circulation Journal Vol.24 No.6

전통주머니에 대한 고찰

박혜순,이상은 한복문화학회 2009 한복문화학회 학술대회 Vol.2009 No.4