기계학습을 활용한 지하 공동구 내부 환경 예측

김다인,이인복,정우석,이병진 한국건축친환경설비학회 2023 한국건축친환경설비학회 논문집 Vol.17 No.4

Underground utility tunnel is located underground, which makes the ventilation system operation and internal environment monitoring important. By designing a machine learning regression model for predicting the internal environment, the effects of the input variables were verified. Temperature, relative humidity and fan operation hour data was collected hourly by sensors installed near the exhaust fan. The external weather data was obtained from the nearest meteorological station in the same experimental period. The results of machine learning regression analysis model showed accuracy of random forest (R2 : 0.891), support vector regression (0.800), k-nearest neighbor (0.774), and multi linear regression (0.744). In order to design the accurate model, the n estimator was set to 157, in which the accuracy of temperature prediction was 0.837 by R2 , and the accuracy of humidity prediction was 0.950. Using the RF model, the correlating factors correlating were verified and the internal environment of underground utility pipe according to fan operation time was verified.

Human exposure analysis study according to Phthalate regulation

김다인,박승영,용도경,김종수,오금순,신영민 환경독성보건학회 2023 한국독성학회 심포지움 및 학술발표회 Vol.2023 No.11

Target-Responsive Template Structure Switching-Mediated Exponential Rolling Circle Amplification for the Direct and Sensitive Detection of MicroRNA

김다인,이지영,박상우,박주현,서명지,이원종,김은정 한국바이오칩학회 2022 BioChip Journal Vol.16 No.4

This study reports a fast and straightforward detection of cancer-specific microRNA (miRNA) via isothermal toehold-mediated rolling circle amplification (TRCA) with a dumbbell (DB) template and DNA-tethered gold nanoparticles (GNP-DNA). A preassembled DB template with a specific structure switching to target miRNA and fine-tuning of the surface coverage of GNP-DNA allows the development of a universal and direct miRNA detection platform without the need for washing, labeling, or isolation. This study demonstrates the successful development of the TRCA and visualization method of amplified products with the naked eye that can precisely and rapidly detect the presence of miRNA-21 with a detection limit of 0.87 nM within 1 h using a standard laboratory plate reader. This approach is further extended to initiate subsequent rounds of exponential amplification with the addition of primers (termed hyperbranched TRCA or HTRCA), providing a 1.6-fold improvement in assay sensitivity with a detection limit of 0.55 nM. Fluorescent detection signals are also used to quantify the amplified products, providing a detection limit of 33 pM (for TRCA) and 31 pM (for HTRCA). Thus, this colorimetric and fluorescent assay can be used as an effective molecular diagnostic tool for target biomolecules with a combination of additional signal amplification strategies.

국내·외 수소충전소 및 배관망 핵심 부품 기술 동향에 관한 연구

김다인,김소현,이효렬 한국에너지학회 2022 한국에너지공학회 학술발표회 Vol.2022 No.4

Generation and characterization of monoclonal antibodies to the Ogawa lipopolysaccharide of Vibrio cholerae O1 from phage-displayed human synthetic Fab library

김다인,홍지수,최윤주,한재민,김상규,조경희,윤준열,채희수,윤혜선,이찬규,홍효정 한국미생물·생명공학회 2020 Journal of microbiology and biotechnology Vol.30 No.11

Vibrio cholerae, cause of the life-threatening diarrheal disease cholera, can be divided into different serogroups based on the structure of its lipopolysaccharide (LPS), which consists of lipid-A, corepolysaccharide and O-antigen polysaccharide (O-PS). The O1 serogroup, the predominant cause of cholera, includes two major serotypes, Inaba and Ogawa. These serotypes are differentiated by the presence of a single 2-O-methyl group in the upstream terminal perosamine of the Ogawa O-PS, which is absent in the Inaba O-PS. To ensure the consistent quality and efficacy of the current cholera vaccines, accurate measurement and characterization of each of these two serotypes is highly important. In this study, we efficiently screened a phage-displayed human synthetic Fab library by bio-panning against Ogawa LPS and finally selected three unique mAbs (D9, E11, and F7) that specifically react with Ogawa LPS. The mAbs bound to Vibrio cholerae vaccine in a dose-dependent fashion. Sequence and structure analyses of antibody paratopes suggest that IgG D9 might have the same fine specificity as that of the murine mAbs, which were shown to bind to the upstream terminal perosamine of Ogawa O-PS, whereas IgGs F7 and E11 showed some different characteristics in the paratopes. To our knowledge, this study is the first to demonstrate the generation of Ogawa-specific mAbs using phage display technology. The mAbs will be useful for identification and quantification of Ogawa LPS in multivalent V. cholerae vaccines.

부모의 합리적 설명 양육행동 수준에 따른 자녀의 성장신념과 학업 스트레스의 변화추이 및 종단적 관계

김다인,안도희 인하대학교 교육연구소 2019 교육문화연구 Vol.25 No.2

This study examined the trends of students’ growth mindset and academic stress by the level of their parents’ rational parenting behavior(RPB) and the longitudinal relations of RPB, students’ growth mindset, and academic stress using 2158 students’ data from the 1st to 6th year of the Gyeonggi Education Panel Study. As a result of K-means cluster analysis using the data from the 1st to 6th year, subjects were classified into 2 clusters(i.e., high-level and low-level RPB groups). In the case of growth mindset, high-level RPB group was significantly higher than low-level RPB group. In the case of academic stress, low-level RPB group was significantly higher than high-level RPB group. As the grade increased, growth mindset tended to significantly decrease, and academic stress tended to significantly increase. Especially, academic stress increased rapidly during the transition period. As a result of examining the longitudinal relations between RPB, students’ growth mindset, and academic stress, RPB positively affected on growth mindset and decreased students’ academic stress. The results of this study are expected to help the development of child-rearing programs and can be used as basic data for parent counseling at school. 본 연구에서는 경기교육종단연구 1~6차 년도 2158명의 데이터를 사용하여 부모의 합리적 설명 양육행동 수준에따른 자녀의 성장신념과 학업 스트레스 변화추이를 살펴보고 부모의 합리적 설명 양육행동, 자녀의 성장신념과 학업스트레스 간의 종단적 관계를 살펴보았다. 먼저 1-6차 년도 데이터를 사용하여 k-평균 군집분석을 수행한 결과, 합리적설명 상 집단과 합리적 설명 하 집단으로 나타났다. 성장신념의 경우, 합리적 설명 상 집단이 합리적 설명 하 집단에비해 높은 수준을 보였으며, 학업 스트레스의 경우에는 합리적 설명 하 집단이 합리적 설명 상 집단에 비해 유의하게높은 것으로 나타났다. 학년이 높아질수록 성장신념은 유의하게 감소하는 경향을 보였으며, 학업 스트레스는 유의하게증가하는 경향을 보였다. 특히 학업 스트레스는 전환기 시기(초6-중1)에 급격하게 증가하였다. 부모의 합리적 설명양육행동, 성장신념과 학업 스트레스 간의 종단적 관계를 살펴본 결과, 부모의 합리적 설명 양육행동이 성장신념에긍정적인 영향을 미치며, 학업 스트레스를 감소시키는 것으로 나타났다. 본 연구결과는 자녀 양육을 위한 프로그램개발에 도움을 줄 수 있으며, 학교현장에서 학부모 상담의 기초자료로 사용될 수 있을 것으로 기대된다.

세계인이 입는 한복

김다인 샘터사 1996 월간 샘터 Vol.27 No.2

직업계 고등학교 학생들의 진로장벽 인식 수준에 따른 진로탄력성과 진로준비행동 차이

김다인,안도희 인하대학교 교육연구소 2019 교육문화연구 Vol.25 No.4

This study explored the cluster types that exist within the sub-factors of career barrier levels as perceived by vocational high school students. Specifically, the study sought to determine if differences exist in career resilience and career preparation behavior based on the career barriers clustering groups. The subjects of this study were 694 students in specialized high schools and meister high schools. Hierarchical cluster analysis showed that students were classified into four groups(“career reality awareness group”, “high career barriers group”, “vulnerable internal career factor group”, “low career barriers group”) based on the scores of sub-factors of perceived career barrier levels. Among students in specialized high school, the highest percentage was the “high career barriers group”. In the case of meister high school students, however, the cluster with the lowest percentage was the “high career barriers group”. Differences existed based on the career barriers clustering groups. In the case of career resilience, the “low career barriers group” demonstrated a higher degree of self-reliance, achieving aspirations, career independence, and active coping than “career reality awareness group”, “vulnerable internal career factor group”, and “high career barriers group”. In the case of career preparation behavior, “career reality awareness group” demonstrated higher all sub-factors of career preparation behavior than “vulnerable internal career factor group”, and “high career barriers group”. These results are expected to assist further exploration on how to improve career resilience and career preparation behavior on the part of vocational high school students for their successful employment and ability to achieve career goals. 본 연구에서는 특성화 고등학교와 마이스터 고등학교에 재학 중인 694명의 학생들을 대상으로 진로장벽의 하위요인인식 수준에 따른 군집유형을 탐색하고 진로장벽 군집유형에 따라 진로탄력성과 진로준비행동에 차이를 보이는지확인하였다. 진로장벽의 하위요인 인식 수준에 따른 군집유형을 탐색한 결과, ‘진로 현실여건 인식집단’, ‘진로장벽고집단’, ‘진로 내적요인 취약집단’, ‘진로장벽 저집단’으로 총 4개의 군집으로 구분되었다. 특성화 고등학교 학생들의경우, ‘진로장벽 고집단’에 속한 비중이 가장 컸던 반면, 마이스터 고등학교 학생들의 경우, ‘진로장벽 저집단’에속한 비중이 가장 큰 것으로 나타났다. 다음으로 진로장벽 군집유형에 따른 진로탄력성의 하위요인 별 차이를 살펴본결과, ‘진로장벽 저집단’, ‘진로 현실여건 인식집단’, ‘진로 내적요인 취약집단’, ‘진로장벽 고집단’ 순으로 ‘자기신뢰’, ‘성취열망’, ‘진로자립’ 및 ‘변화대처’ 요인의 수준이 높은 것으로 나타났다. 진로준비행동의 경우, ‘진로 현실여건인식집단’이 ‘진로 내적요인 취약집단’과 ‘진로장벽 고집단’에 비해 모든 요인의 수준이 높은 것으로 나타났다. 본연구는 직업계 고등학교 학생들의 성공적인 취업과 진로목표 달성을 위한 진로탄력성과 진로준비행동 증진 방안을탐색하는데 도움을 줄 수 있을 것으로 기대된다.

대학생의 감사, 낙관성, 우울 및 행복감의 구조적 관계: 성별 차이를 중심으로

김다인,안도희 한국교육학회 2019 敎育學硏究 Vol.57 No.1

This study aimed to examine the relationship between gratitude, optimism, depression and happiness of university students along with gender. The participants were 581 university students in Seoul, Korea. Female students’ level of depression was significantly higher than male students’ level of depression. As a result of examining the structural relationships between gratitude, optimism, depression and happiness through structural equation modelling(SEM), gratitude and optimism negatively influenced on depression, whereas gratitude directly positively influenced on happiness. Depression decreased happiness and mediated the relation of optimism and happiness. Male students were stronger than female students in the influence of optimism on happiness. This study is meaningful in that it has identified the structural relations between gratitude, optimism, depression, and happiness of university students. Futhermore, this study will be used as preliminary data to develop program for enhancing university students’ happiness. 본 연구에서는 대학생의 감사, 낙관성, 우울 및 행복감 간의 구조적 관계를 살펴보고 성별에 따른 차이를 확인하고자 하였다. 서울 소재 4년제 A대학교 581명을 대상으로 분석한 결과, 여학생이 남학 생에 비해 우울 수준이 유의하게 높은 것으로 나타났다. 구조방정식을 통해 감사, 낙관성, 우울 및 행 복감의 구조적 관계를 살펴본 결과, 감사와 낙관성은 우울을 감소시켰으며, 감사는 행복감에 직접적으 로 긍정적인 영향을 주었다. 우울은 행복감을 감소시키며, 낙관성과 행복감 간의 관계를 매개하는 것 으로 나타났다. 또한 낙관성이 행복감에 미치는 영향은 여학생에 비해 남학생이 유의하게 강한 것으 로 나타났다. 본 연구는 대학생의 감사, 낙관성, 우울 및 행복감 간의 구조적 관계를 파악했다는데 의 미가 있으며, 대학생의 행복감 증진을 위한 프로그램 개발의 기초자료로 활용될 수 있을 것으로 기대 된다.

Effects of various types of bridge exercise on pain, back pain disability index and abdominal muscle thickness in patients with chronic low back pain

김다인,정지운,김대훈,허진강 대한치료과학회 2017 대한치료과학회지 Vol.9 No.2

Objective: The purpose of this study was to investigate the effects of stabilization training on bridge exercise type on pain, back pain disability index and abdominal muscle thickness in patients with chronic low back pain Method: 20 patients with chronic low back pain were divided into three groups: a bridging exercise of resistance with upper limb movement, a bridging exercise on unstable surface, and a bridging exercise of general. The exercises were conducted for 30 minutes, 3 times a week (total; 24 times for 8 weeks). Pain, back pain disability index, thickness of abdominal muscles (transvers abdominis, external oblique, internal oblique) were measured before the training and at 4 weeks and 8 weeks after the intervention. Comparison of the time dependent variable for each group was calculated by Repeated measures ANOVA. Comparison among the three groups was calculated by an One-way ANOVA. Results: All three groups had significant differences in pain, back pain disability index, and abdominal muscle thickness (p<.05). There was no significant difference between the three groups in the inter-group analysis. Conclusion: The results of this study showed that bridging exercise of resistance with upper limb movement, bridging exercise on unstable surface, and a bridging exercise of general are an effective therapy for pain, back pain disability index, thickness of abdominal muscles in patients with chronic low back pain. These results suggest that a bridging exercise of general can be effective for patients with low back pain without resistance or external factors which may be difficult to perform.