건강한 성인 남성에서 측정 자세가 폐 기능 검사 결과에 미치는 영향

신정우,김성태,이준희 대한심장호흡물리치료학회 2024 대한심장호흡물리치료학회지 Vol.12 No.1

Purpose: This study aimed to determine whether forced vital capacity, forced expiratory volume in 1 s, forced expiratory volume in 1 s/forced vital capacity, maximum expiratory flow rate, and maximum inspiratory/expiratory pressure vary according to the test posture. Methods: For this purpose, 30 healthy university students in their 20s were assessed in the supine position, 45° sitting position, and 90° sitting position for forced vital capacity, forced expiratory volume in 1 s, forced expiratory volume in 1 s/forced lung capacity, peak expiratory flow, maximum inspiratory/expiratory pressure, and the results were statistically analyzed using one-way analysis of variance and Bonferroni post-hoc test. Results: A significant difference was found between the supine position, forced lung capacity, and forced expiratory volume in 1 s in 90° sitting position (p<.05); however, no significant difference was found between forced expiratory volume/forced vital capacity, peak expiratory flow, and maximal inspiratory/expiratory pressure in 1 s (p>.05). Conclusion: The results showed that assessment in the supine or 45° sitting position rather than in the 90° sitting position affects breathing but not respiratory muscle strength.

Utility of a forced expiratory flow of 25 to 75 percentas a predictor in children with asthma

강정완,김경원,김은수,박준영,손명현,김규언 대한소아청소년과학회 2008 Clinical and Experimental Pediatrics (CEP) Vol.51 No.3

Purpose:Asthma is defined as chronic inflammation of the lower small airways, and bronchial hyperreactivity (BHR) is a pathophysiologic feature of asthma. It has been proposed that although there is no direct variable capable of assessing the small airways, a forced expiratory flow of between 25 and 75 percent (FEF25-75) might be considered a more sensitive early marker of small airway obstruction than the forced expiratory volume in 1 second (FEV1). Thus, we proposed that the presence and degree of positive responses to bronchial methacholine testing were related to the difference (DFF) and ratio (RFF) between FEV1 and FEF25-75 in asthmatic children. Methods:The subjects were 583 symptomatic children, including 324 children with BHR and 259 controls. Pulmonary function tests, methacholine challenge tests, and skin prick tests were performed, and the total eosinophil count, total serum IgE, and serum eosinophil cationic protein level were measured in all subjects. From a concentration-response curve, the methacholine concentration required to produce a decrease of 20% from post-saline FEV1 was calculated (PC20). Results:The median DFF and RFF values decreased in controls compared to subjects with bronchial hyperresponsiveness, and this trend was found in groups ranked by its severity. PC20 had a negative correlation with DFF and RFF. Cutoff values of 0.5 for DFF and 1.042 for RFF were identified, and sensitivity and specificity were calculated. Conclusion:This study revealed that DFF and RFF might be predictive of bronchial hyperresponsiveness in the context of normal FEV1 in children. (Korean J Pediatr 2008;51:323-328) Purpose:Asthma is defined as chronic inflammation of the lower small airways, and bronchial hyperreactivity (BHR) is a pathophysiologic feature of asthma. It has been proposed that although there is no direct variable capable of assessing the small airways, a forced expiratory flow of between 25 and 75 percent (FEF25-75) might be considered a more sensitive early marker of small airway obstruction than the forced expiratory volume in 1 second (FEV1). Thus, we proposed that the presence and degree of positive responses to bronchial methacholine testing were related to the difference (DFF) and ratio (RFF) between FEV1 and FEF25-75 in asthmatic children. Methods:The subjects were 583 symptomatic children, including 324 children with BHR and 259 controls. Pulmonary function tests, methacholine challenge tests, and skin prick tests were performed, and the total eosinophil count, total serum IgE, and serum eosinophil cationic protein level were measured in all subjects. From a concentration-response curve, the methacholine concentration required to produce a decrease of 20% from post-saline FEV1 was calculated (PC20). Results:The median DFF and RFF values decreased in controls compared to subjects with bronchial hyperresponsiveness, and this trend was found in groups ranked by its severity. PC20 had a negative correlation with DFF and RFF. Cutoff values of 0.5 for DFF and 1.042 for RFF were identified, and sensitivity and specificity were calculated. Conclusion:This study revealed that DFF and RFF might be predictive of bronchial hyperresponsiveness in the context of normal FEV1 in children. (Korean J Pediatr 2008;51:323-328)

Lung Function of Grain Millers Exposed to Grain Dust and Diesel Exhaust in Two Food Markets in Ibadan Metropolis, Nigeria

Kemi Iyogun,Suraju A. Lateef,Godson R.E.E. Ana 한국산업안전보건공단 산업안전보건연구원 2019 Safety and health at work Vol.10 No.1

Background: Despite growing concern over occupational exposure to particulate matter (PM) such as grain dust and diesel exhaust, information about the exposure level and health implications among workers in small-scale milling enterprises in developing countries like Nigeria has not been adequately documented. The purpose of this study was to assess the level of exposure to grain dust and diesel exhaust and effect on lung function among grain millers in food markets in Ibadan metropolis, Nigeria. Methods: The study adopted descriptive cross-sectional design with a comparative approach. Sixteen grain milling shops each were randomly selected from two major food markets in Ibadan metropolis for indoor PM10 and PM2.5 monitoring. Seventy-two respondents each were proportionately selected from grain millers and shop owners for forced expiratory volume in one second and peak expiratory flow rate tests. Results: The PM2.5 concentrations for both market locations ranged between 1,269.3 and 651.7 mg/m3, while PM10 concentrations were between 1,048.2 and 818.1 mg/m3. The recorded concentrations exceeded the World Health Organization guideline limit of 50 mg/m3 and 25 mg/m3 for PM2.5 and PM10, respectively. As compared with control group (2.1 L), significantly lower forced expiratory volume in one second value (1.61 L) was observed among the exposed group (p < 0.05). Likewise, significantly lower peak expiratory flow rate value (186.7 L/min) was recorded among the exposed group than the control group (269.51 L/min) (p < 0.05). Conclusion: Exposure to grain dust and diesel exhaust accentuated respiratory disorders with declines in lung functions amongst grain millers. Improved milling practices and engaging cleaner milling facilities should be adopted to minimize exposure and related hazards.

Lung Function of Grain Millers Exposed to Grain Dust and Diesel Exhaust in Two Food Markets in Ibadan Metropolis, Nigeria

Iyogun, Kemi,Lateef, Suraju A.,Ana, Godson R.E.E. Occupational Safety and Health Research Institute 2019 Safety and health at work Vol.10 No.1

Background: Despite growing concern over occupational exposure to particulate matter (PM) such as grain dust and diesel exhaust, information about the exposure level and health implications among workers in small-scale milling enterprises in developing countries like Nigeria has not been adequately documented. The purpose of this study was to assess the level of exposure to grain dust and diesel exhaust and effect on lung function among grain millers in food markets in Ibadan metropolis, Nigeria. Methods: The study adopted descriptive cross-sectional design with a comparative approach. Sixteen grain milling shops each were randomly selected from two major food markets in Ibadan metropolis for indoor $PM_{10}$ and $PM_{2.5}$ monitoring. Seventy-two respondents each were proportionately selected from grain millers and shop owners for forced expiratory volume in one second and peak expiratory flow rate tests. Results: The $PM_{2.5}$ concentrations for both market locations ranged between 1,269.3 and $651.7{\mu}g/m^3$, while $PM_{10}$ concentrations were between 1,048.2 and $818.1{\mu}g/m^3$. The recorded concentrations exceeded the World Health Organization guideline limit of $50{\mu}g/m^3$ and $25{\mu}g/m^3$ for $PM_{2.5}$ and $PM_{10}$, respectively. As compared with control group (2.1 L), significantly lower forced expiratory volume in one second value (1.61 L) was observed among the exposed group (p < 0.05). Likewise, significantly lower peak expiratory flow rate value (186.7 L/min) was recorded among the exposed group than the control group (269.51 L/min) (p < 0.05). Conclusion: Exposure to grain dust and diesel exhaust accentuated respiratory disorders with declines in lung functions amongst grain millers. Improved milling practices and engaging cleaner milling facilities should be adopted to minimize exposure and related hazards.

흉곽저항운동이 만성폐쇄성폐질환 환자의 1초간 노력성 호기량과 피로도에 미치는 영향

강정일,정대근,박승규,이준희,Kang, Jeong-Il,Jeong, Dae-Keun,Park, Seung-Kyu,Lee, Jun-Hee 대한물리치료학회 2011 대한물리치료학회지 Vol.23 No.2

Purpose: The purpose of this study was to determine the effects of chest resistance exercise on Forced Expiratory Volume per second and on fatigue in patients with chronic obstructive pulmonary disease (COPD). Methods: In all, 62 male patients with COPD were included in this study. The experimental group included 32 patients who were treated with chest resistance exercise using the PNF technique with medication. The control group included 30 patients who were treated only with medication. Subjects were stratified into the 2 groups by randomized clinical sampling. Before the start of the experiment, forced expiratory volume at the first second (FEV1) and lactic acid were tested in both experimental and control groups. The experimental group did chest resistance exercise for 6 weeks, 4 times per week, 30 min per day, and the effects of this exercise in patients with COPD was determined by comparing the results of FEV1 and lactic acid tests before and after the experiment between and within the experimental and control groups. Results: There was a statistically significant within group difference for FEV1 MEAS and FEV1 %PRED. There was statistically significant control group of FEV1 MEAS and FEV1 %PRED There was a statistically significant difference in the experimental group for fatigue, comparing scores before and after the test. There was a statistically significant control group of fatigue, in comparison of between the groups of FEV1 MEAS, FEV1 %PRED, fatigue(p<0.01)(p<0.05). Conclusion: More research on COPD will be necessary for improving pulmonary function and reducing fatigue. Further studies on COPD will be required for improving pulmonary function and reducing of fatigue.

근로자건강진단 폐활량검사에서 새로운 신뢰성기준 적용 결과

원용림,LEE Hwa-Yeon,LEE Jihye 대한임상검사과학회 2023 대한임상검사과학회지(KJCLS) Vol.55 No.4

The Occupational Safety and Health Research Institute is currently evaluating spirometry tests used for worker health examinations by applying the 2005 American Thoracic Society (ATS) and European Respiratory Society (ERS) spirometric test standardization guide and reviewing the application of the 2019 ATS/ERS guide. To compare results obtained using the new evaluation criteria with previous results and determine whether it is appropriate to apply them to Korean workers’ health examinations, we reviewed spirometry results from 325 special health examination institutions. Although evaluation criteria such as extrapolation volume, correction error, and forced inspiratory vital capacity were applied more strictly, institutions had higher reliability scores. Primarily because the acceptability and repeatability of forced expiratory volume in 1 second and forced vital capacity were judged separately, and thus, deduction width was reduced. The study shows that adopting the new evaluation criteria would reduce the possible use of inappropriate data, increase tester and doctor understanding of result selection and interpretation, increase result reliability, and reduce the testing burden.

Rapid FEV 1 /FVC Decline Is Related With Incidence of Obstructive Lung Disease and Mortality in General Population

Choi Kwang Yong,Lee Hyo Jin,Lee Jung-Kyu,Park Tae Yun,Heo Eun Young,김덕겸,이현우 대한의학회 2023 Journal of Korean medical science Vol.38 No.1

Background: Forced expiratory volume in 1 second (FEV1)/forced vital capacity (FVC) naturally decreases with age; however, an excessive decline may be related with increased morbidity and mortality. This study aimed to evaluate the FEV1/FVC decline rate in the Korean general population and to identify whether rapid FEV1/FVC decline is a risk factor for obstructive lung disease (OLD) and all-cause and respiratory mortality. Methods: We evaluated individuals aged 40−69 years who underwent baseline and biannual follow-up spirometric assessments for up to 18 years, excluding those with airflow limitations at baseline. Based on the quartiles of the annual FEV1/FVC decline rate, the most negative FEV1/FVC change (1st quartile of annual FEV1/FVC decline rate) was classified as rapid FEV1/ FVC decline. We investigated the risk of progression to OLD and all-cause and respiratory mortality in individuals with rapid FEV1/FVC decline. Results: The annual FEV1/FVC decline rate in the eligible 7,768 patients was 0.32 percentage point/year. The incidence rate of OLD was significantly higher in patients with rapid FEV1/ FVC decline than in those with non-rapid FEV1/FVC decline (adjusted incidence rate, 2.119; 95% confidence interval [CI], 1.932–2.324). Rapid FEV1/FVC decline was an independent risk factor for all-cause mortality (adjusted hazard [HR], 1.374; 95% CI, 1.105–1.709) and respiratory mortality (adjusted HR, 1.353; 95% CI, 1.089–1.680). Conclusion: The annual FEV1/FVC decline rate was 0.32%p in the general population in Korea. The incidence rate of OLD and the hazards of all-cause and respiratory mortality were increased in rapid FEV1/FVC decliners.

폐기능과 요산 수치와의 관련성

김기태,설재웅 대한임상건강증진학회 2019 Korean Journal of Health Promotion Vol.19 No.4

Background: Forced vital capacity (FVC), forced expiratory volume in the first second (FEV1), and the ratio of FEV1 to FVC (FEV1/FVC) are considered as the major spirometry parameters. Serum uric acid is associated with increased risk of gout and cardiovascular disease. We analyzed the relationship between pulmonary function and serum uric acid level in the Korean men and women. Methods: This study was based on the data collected during the 2016 Korea National Health and Nutrition Examination Survey (KNHANES VII-1). A total of 3,411 adults were retrieved from KNHANES VII-1. Among 3,411 adults, 1,500 were men and 1,911 were women. Results: In this study, a significant negative correlation was observed between serum uric acid level and pulmonary function values only in females. Also, in the male non-smoker group, pulmonary function values were negatively associated with serum uric acid level (FVC %predicted, β=-0.014; FEV1 %predicted, β=-0.015). Conclusions: In this study, hyperuricemia was associated with the low lung function in males and females. In order to obtain an accurate assessment of the association between hyperuricemia and pulmonary function values, further prospective cohort study in the future is necessary. 연구배경: 강제폐활량과 1초간 강제호기량 등은 폐기능의지표로 측정된다. 또한 요산 수치는 통풍과 심혈관 질환의위험요인이다. 본 연구에서는 한국인 남성과 여성에서 폐기능과 요산 수치와의 관련성을 분석하였다. 방법: 연구 대상자는 2016년 국민건강영양조사에 참여한3,411명의 성인이다. 남성 1,500명, 여성 1,911명이 분석에포함되었다. 결과: 여성에서 폐기능과 요산 수치와의 음의 상관성을 보였다. 남성의 경우에는 비흡연자에서 폐기능과 요산과의 통계학적으로 유의한 음의 상관성이 있었다. 남성에서의 1초간 강제호기량이 낮은 사람은 1초간 강제호기량이 높은 사람들에 비해서 고요산혈증과 유의한 관련성이 있었다. 여성에서도 강제폐활량이 낮은 사람은 강제폐활량이 높은 사람들에 비하여 고요산혈증과 유의한 관련성이 있었다. 결론: 본 연구에서 고요산혈증은 남성과 여성 모두에서낮은 폐기능과 관련이 있었다. 인과관계를 더 정확히 알기위해서는 추후 전향적인 코호트 연구가 필요하겠다.

미용코르셋이 여대생 폐활량에 미치는 영향

김기송(Ki-Song Kim) 대한심장호흡물리치료학회 2016 대한심장호흡물리치료학회지 Vol.4 No.1

Purpose : This study aimed to investigate the influence of lung function according to a variety of corset pressures. Method : Total 15 healthy women (21.3±0.7 years, 56.1±5.5 weight) were recruited in this study. All participants wore a corset with pressures (0 mmHg, 10 mmHg, or 30 mmHg) in a sitting position, and then measured forced vital capacity (FVC), forced expiratory volume in 1 sec (FEV 1 ), and maximum inspiratory pressure (MIP) using a spirometer. Results : The FVC and MIP values showed significantly decreases according to the pressure increases. Also, FEV 1 significantly reduced in wearing a corset with 10mmHg compared to 0mmHg. Conclusion : These findings indicate that wearing a corset with greater pressure (30mmHg) might influence on lung capacity. It can be explained that wearing a corset might limit abdominal mobility, which increases intra-abdominal pressure. Therefore, these findings suggest wearing a corset with greater pressure should be considered for further lung capacity.

The Relationship between Metabolic Syndrome and Pulmonary Function

배명숙,한지혜,김정환,김영주,이경진,권길영 대한가정의학회 2012 Korean Journal of Family Medicine Vol.33 No.2

Background: Impaired lung function is associated with mortality rate from cardiovascular and all other death causes. There were previous studies on the relationship between lung function impairment and metabolic syndrome, but they are insuffi cient. This study was conducted on Koreans to analyze each component of metabolic syndrome as well as its variability between sexes. Methods: 1,370 subjects underwent a health examination at the Eulji General Hospital Health Center. We examined the association between lung function measurement (forced expiratory volume for 1 second [FEV1], forced vital capacity [FVC], FEV1/FVC) and metabolic syndrome using Student t-test, Pearson partial correlation coeffi cient, and analysis of covariance for statistical analysis, and we adopted metabolic syndrome defi ned by American Heart Association/National Heart, Lung, and Blood Institute in Asia. Results: Men with metabolic syndrome tended to experience lung function impairment. In terms of association to each metabolic syndrome component, metabolic syndrome components in men were associated with pulmonary function impairment and the more metabolic syndrome diagnostic criteria factors the patients had, the more severe their pulmonary function tended to decline. In women, waist circumference, triglyceride and high-density lipoprotein cholesterol were associated with pulmonary function change. Conclusion: In men, all metabolic syndrome components were associated with pulmonary function impairment, and the more metabolic syndrome components men had, the more severe their pulmonary functions decline. In women,components of metabolic syndrome were not associated with pulmonary function impairment.