심근 허혈-재관류 백서 모델에서 mitogen-activated protein kinase 활성화에 대한 α-lipoic acid의 효과

김연경,박은미,최준호,윤경호,유남진,이은미,김남호,정진원,김민선,박병림,오석규 圓光大學校 醫科學硏究所 2006 圓光醫科學 Vol.21 No.1

자료포락분석(DEA)를 이용한 보건의료의 효율성 측정

김남송,박홍섭,김은진,김설화,김정숙,김현아,김경숙,신지혜,최은정,양은진,유선미,유수진 圓光大學校 醫科學硏究所 2007 圓光醫科學 Vol.22 No.1

관절염을 가진 대상자의 가족지지, 자가 간호 및 삶의 질과의 관계

선은경,박소연,박일지,서가은,손용숙,손인옥,용진선 가톨릭대학교 간호대학 호스피스 교육연구소 2006 호스피스논집 Vol.10 No.-

Purpose : The purpose of this study was to investigate relationships among family support, self-care, and quality of life of patients with arthritis through a survey. That will be basic data to plan nursing intervention for promoting quality of life for patients with arthritis. Method : The convenient sample of this study consisted of 120 patients with arthritis and data were collected using questionnaires during August 2006 from two OPDs of rheumatoid centers in C University hospitals. The study instruments were used to measure Self Care (So, 1992), Family Support (Kang, 1984), and Quality of Life (Ro, 1988). The data were analyzed using ANOVA, Duncan test, and Pearson correlation. Result : The mean scores were 3.56 for family support, 4.16 for self-care, and 3.19 for quality of life. The level of self-care was significantly higher in those men, having an occupation, higher income, and living with family members. The level of family support was significantly higher in those men, having an occupation, living with family members, and having a helper. The level of quality of life was significantly higher for those men, having a higher income, and shorter length of illness. Three relationships were found to be positively correlated: 1) between the levels of family support and self-care (r=.53), 2) between the levels of self-care and quality of life (r=.55), and 3) between the levels of family support and quality of life (r=.54). Conclusion: Therefore, a nursing intervention program needs to be developed to promote family support, and self-care for quality of life for patients with arthritis.

한국판 사건충격척도 수정판의 신뢰도 및 타당도 연구

은헌정,권태완,이선미,김태형,최말례,조수진 大韓神經精神醫學會 2005 신경정신의학 Vol.44 No.3

Objectives : The present study was conducted to explore the reliability and validity of the "Impact of Event Scale-RevisedKorean version" (IES-R-K). Methods : The subjects were college students who visited a college counseling center and patients who were admitted to a general hospital and two orthopedic local clinics.Those subjects who experienced catastrophic traumatic events were tested for CAPS, BDI, STAI-I, II, and MMPI-PTSD scale. Results : The range of correlations between item-total were .45 -.89. The coefficients of internal consistency were .69 -.83, of them were the Split-half reliability was .71 and the test-retest reliability was .89, all within expected ranges. Inter-corre-lations of IES-R-K, CAPS, BDI, STAI-I, II, and MMPI-PTSD scale were high. CAPS showed the highest correlation Coef-ficient. Factor analysis indicated 4 factors in IES-R ; avoidance, hyperarousal, intrusion, and sleep problem & numbness. IES-R-K can be a useful self-rating diagnostic instrument for PTSD symptoms to be a clinical concern by using 24/25 cutoff in total score. The partial PTSD cutoff score is 17/18. Conclusion : The IES-R-K was confirmed in it's reliability and validity. IES-R-K could be applied for screening of PTSD.

Inoue Balloon을 이용한 PMV의 장·단기 결과 분석

진은선,이연아,전숙,김현숙,정승묵,박상선,최락경,임달수,홍석근,황흥곤 대한순환기학회 2003 Korean Circulation Journal Vol.33 No.11

노인수발보장제도 도입에 따른 노인주간보호시설의 수요증가와 시설변화에 관한 연구

오은진,박혜선 한국의료복지시설학회 2006 의료·복지 건축 Vol.12 No.2

Introduction of new longterm care policy for elderly in Korea would change many aspects of elderly care service facilities. Especially elderly home care services like adult daycare centers will expand drastically after beginning of longterm care insurance. The purpose of this study is to estimate demand of adult daycare centers by comparing with the U.S and Japanese cases. Korean government is expecting that adult daycare centers will expand ten times within 4 years. This estimate is exceeding the facility demand estimate of the U.S. and Japan. The results of population study and expecting growth rate of adult daycare centers in Seoul indicate that more than 300 centers, 4 times of the number of existing centers, are in need based on Seoul elderly population in 2004. To supply these numbers of facilities in short period, more in depth study should be followed. Existing adult daycare facilities’ in Seoul were analyzed by their building and management types. Interior spaces of adult daycare centers in Korea are similar to the U.S. and Japan in space arrangements but much smaller in size. In depth study of space programming as well as overall demand survey of adult daycare centers is urgently in need for more realistic expansion of adult daycare centers.

Alendronate가 흰쥐 뼈끝 연골판 성장에 미치는 영향

김현진,이은주,이계혁,김민석,김선헌 전남대학교 치의학연구소 2003 구강과학 Vol.15 No.2

Bisphosphonates inhibit bone resorption by affecting osteoclastic function and formation of osteoclasts from their precursor cells. Chondroclasts have the same origin and differentiation as osteoclasts. Thus, it is hypothesized that bisphosphonate can affect on cartilage metabolism. This study was aimed to elucidate effects of alendronate, a nitrogen containing bisphosphonate, on cartilage development in the tibial proximal and femoral distal epiphyseal plates in rats. Alendronate (1 mg/kg) was subcutaneously administered in growing rat pups for 10 days. Several parameters such as the number and size of chondroclasts, involved in cartilage resorption, size of secondary ossification center and thickness of cartilage cell layers were measured and analysed by histomorphometry. The size of the secondary ossification centers in the tibial proximal and femoral distal epiphysis was smaller in the alendronate treated group (p<0.01). The number of osteoclasts in the both the ossification centers and chondroclasts beneath the epiphyseal plates was significantly decreased byalendronate treatment (p<0.01). The size of chondroclasts was not significantly changed (p>0.05). The thickness of proliferating cartilage layer was not changed, but by contrast, hypertrophied cartilage layer was increased in thickness by alendronate treatment. These findings suggest that bisphosphonates can affect cartilage cell metabolism in a chondroprotective way.

담즙정체성 간염의 임상적 양상

최선택,은종렬,임상우,김봉준,이헌주,구미진,최준혁 영남대학교 기초/임상의학연구소 2001 Yeungnam University Journal of Medicine Vol.18 No.1

Background: Cholestatic hepatitis is failure of bile to reach the duodenum with hepatocellular damage and no demonstrable obstruction of the major bile ducts. The prognosis is usually good with recovery in less than 4 weeks after withdrawal of the offending drug. However, a prolonged course lasting over 3 months is possible and, in rare cases, progression to ductopenia with development of a vanishing bile duct syndrome occurs. A differential diagnosis with other causes of Chronic liver disease is needed. Materials and Methods: From January 1991 through Jaunary 2000, 14 patients diagnosed as cholestatic hepatitis by liver biopsy were inclouded. The possible causative drug, clinical features, laboatory findings, and progression of cholestatic hepatitis were evaluated. The semiquantitative study of liver lesions was performed by two independent observers. Results: Causes of cholestatic hepatitis are 5 cases of oriental medicine, 3 cases of anti-tuberculosis medication, 1 case of ticlopidine and antibiotics and 4 cases of unknown causes. The clinical features of cholestatic hepatitis were jaundice, itching, urine color change, and general weakness. During 6 to 30 months, LFT of 5 patients showed prolonged elevation. Elevated total cholesterol ≥250 mg/dL in 6 patients, pheripheral blood eosinophilia in 5 patients, auto-antibody positive in 6 patients were observed respectively. The biopsies showed intralobular bilirubinostasis with a mixed portal inflammatory infiltration. Conclusion: In cholestatic hepatitis. durations of abnormal LFT are variable regardless of causative drugs. If cholestatic hepatitis progresses toward chronic course, viral hepatitis, primary biliary cirrhosis, and autoimmune hepatitis should be differentially diagnosed and sequential liver biopsies are needed.

흉곽 내시경을 사용한 척추 기형 수술시 학습 곡선

김학선,최윤락,이환모,문성환,김경희,박진오,하중원,신동은 대한척추외과학회 2003 대한척추외과학회지 Vol.10 No.3

김천대학생들의 구취인지 실태에 관한 조사연구

이은숙 ; 김혜진 ; 김희천 ; 최옥선 김천대학교 2003 김천대학교 논문집 Vol.24 No.-

To help the guidance of treatment method, prevention of halitosis, and oral hygiene management for halitosis patient or non-halitosis group for investigating the status in accordance with awareness of halitosis to improve the oral health for college students, the survey including ques- tionnaire was performed for 331 persons of students who is studying in the Gimcheon college located in the northern province of Kyeongsang-Do. As a conclusion, the following data are obtained. 1. For the question of "I am acknowledging the halitosis", the replying person were 123 persons (37.2%), including men-69 persons(20.8%), women-54 persons(16.3%), So, in case of the ratio of acknowledging the halitosis, men was higher than women. On the contrary, for the question of "I do not acknowledging the halitosis", men-68 persons (20.5%), women-140 persons(42.3%), So, in case of the ratio of non-ackowledging the halitosis, men was much higher than women. 2. For the question of "When did you acknowledge the halitosis at most in the whole day?", total of 127 persons(38.4%) said "as soon as get up" out of the 183 persons (55%) who acknowledging the halitosis. The remaining replies were followed in the order of "before breakfast", "after breakfast", and "before sleeping". 3. In the status of oral hygiene, it showed that the persons who acknowledge the halitosis acts positively the frequency of toothbrushing (more than twice a day), method of toothbrushing, and brushing the tongue than the persons who do not acknowledge the halitosis. 4. In the status of smoking habits, there was no increment according to the duration of smoking, but in the status of amount of smoking, the persons who smokes less than half carton a day were 20 (6.0%), half through one carton a day were 31 (9.4%). So, it showed that the amount of smoking is affected to the cause of halitosis. 5. The ordinary prevention methods for oral hygiene according to the awareness of halitosis were investigated in the order of toothbrushing/brushing the tongue (37.3%), chewing the gum (33%), and using the rinsing liquids (12.4%).