산소/철분의 함량변화가 티타늄의 기계적 성질에 미치는 영향

심건주,이강인,장대규,서창열 대한금속재료학회(대한금속학회) 1995 대한금속·재료학회지 Vol.33 No.1

Using a vacuum consumable arc melting furnace, the methods of adding oxygen and iron to pure titanium and the effects of these additives on the mechanical properties of titanium were studied. The chemical composition and mechanical properties of ASTM grads 1, 3 and 4 were used as targets in the experiments. Addition of oxygen in the form of Ti-10wt% O master alloy gave more consistent results than in the form of TiO₂. Iron was added in the form of powder. Under the pressure employed in the main experiment about 20% and 50% of oxygen and iron were found to be a loss in the process of melting, respectively. As a result oxygen and iron contents of the grades 3 and 4 turned out to be a little higher than expected, giving rise to the much higher ultimate tensile strength and yield strength but slightly higher reduction in area than the lower ASTM limits. The grade 1 to which nothing was added was satisfactory both in the chemical composition and mechanical properties.

Ga_xIn_1-xSb_yAs_1-y의 전자적 구조: UTB 방법에 의한 밴드정렬상태

심규리,Shim, Kyu-Rhee 한국진공학회 2011 Applied Science and Convergence Technology Vol.20 No.6

사원화합물 반도체 $Ga_xIn_{1-x}Sb_yAs_{1-y}$을 구성하는 네 가지 이원화합물 반도체 GaAs, GaSb, InAs, InSb의 최고 가전자띠 준위와 최저 전도띠 준위를 밀접결합방법에 근거한 해석적 근사법으로 계산하였다. 이들을 이종 접합시켰을 때 경계면에서의 밴드정렬상태를 구한 결과, GaAs/InAs와 GaAs/InSb, GaSb/InSb는 제 I형, GaAs/GaSb는 제 II형, GaSb/InAs, InSb/InAs는 제III형의 밴드 정렬 형태를 갖는다는 것을 알 수 있었다. 또한 범용적 밀접결합을 이용하여 사원화합물 반도체 $Ga_xIn_{1-x}Sb_yAs_{1-y}$의 성분비 x와 y에 따른 최고 가전자 띠와 최저 전도 띠 준위변화를 구하였다. $Ga_xIn_{1-x}Sb_yAs_{1-y}$을 GaSb와 InAs 격자 정합시켜 경계면에서의 밴드정렬상태를 구해 본 결과 성분비에 따라 제 II형과 제 III형 사이의 밴드정렬형태의 전이가 일어남을 알 수 있었다. $Ga_xIn_{1-x}Sb_yAs_{1-y}$를 GaSb에 격자 정합 시켰을 때 $x{\geq}0.15$에서 제 III형 밴드정렬이었던 것이 $x{\geq}0.81$에서는 제 II형의 밴드정렬 상태로 전이되며, 이와 반대로 $Ga_xIn_{1-x}Sb_yAs_{1-y}$를 InAs에 격자정합 시켰을 때 $x{\geq}0.15$에서 제 II형 밴드 정렬이 $x{\geq}0.81$에서 제 III형 밴드정렬로 전이됨을 알 수 있었다. The valence band maximum and the conduction band miminum of GaAs, GaSb, InAs, and InSb (constituent binaries of the quaternaty alloy $Ga_xIn_{1-x}Sb_yAs_{1-y}$) are calculated by using TB analytical approach method. The band alignment types of their heterojunctions are determined directly from their relative position of band edges (VBM and CBM). For example, the GaAs/InAs, GaAs/InSb, and GaSb/InSb are in a type-I, the GaAs/GaSb in a type-II, and the GaSb/InAs and InSb/InAs in a type-III, respectively. The composition dependent VBM and CBM for the $Ga_xIn_{1-x}Sb_yAs_{1-y}$ alloy are obtained by using the univeral tight binding method. For the alloyed heterojunctions, the band alignments can be controlled by changing the composition which induce a band type transition. For the alloy $Ga_xIn_{1-x}Sb_yAs_{1-y}$ lattice mathced to GaSb, the type-II band alignment in the region of $x{\leq}0.15$ is changed to the type-III in the region of $x{\geq}0.81$. On the other hand, the alloy $Ga_xIn_{1-x}Sb_yAs_{1-y}$ lattice mathced to InAs has the type-II band alignment in the region of $x{\leq}0.15$ and the type-III band alignment in the region of $x{\geq}0.81$, respectively.

Impact of Hospital Volume of Percutaneous Coronary Intervention (PCI) on In-Hospital Outcomes in Patients with Acute Myocardial Infarction: Based on the 2014 Cohort of the Korean Percutaneous Coronary Intervention (K-PCI) Registry

Byong-Kyu Kim,Deuk-Young Nah,Kang Un Choi,Jun-Ho Bae,Moo-Yong Rhee,Jae-Sik Jang,Keon-Woong Moon,Jun-Hee Lee,Hee-Yeol Kim,Seung-Ho Kang,Woo hyuk Song,Seung-Uk Lee,Byung-Ju Shim,Hangjae Chung,Min Su Hyo 대한심장학회 2020 Korean Circulation Journal Vol.50 No.11

Background and Objectives: The relationship between the hospital percutaneous coronary intervention (PCI) volumes and the in-hospital clinical outcomes of patients with acute myocardial infarction (AMI) remains the subject of debate. This study aimed to determine whether the in-hospital clinical outcomes of patients with AMI in Korea are significantly associated with hospital PCI volumes. Methods: We selected and analyzed 17,121 cases of AMI, that is, 8,839 cases of non-ST-segment elevation myocardial infarction and 8,282 cases of ST-segment elevation myocardial infarction, enrolled in the 2014 Korean percutaneous coronary intervention (K-PCI) registry. Patients were divided into 2 groups according to hospital annual PCI volume, that is, to a high-volume group (≥400/year) or a low-volume group (<400/year). Major adverse cardiovascular and cerebrovascular events (MACCEs) were defined as composites of death, cardiac death, non-fatal myocardial infarction (MI), stent thrombosis, stroke, and need for urgent PCI during index admission after PCI. Results: Rates of MACCE and non-fatal MI were higher in the low-volume group than in the high-volume group (MACCE: 10.9% vs. 8.6%, p=0.001; non-fatal MI: 4.8% vs. 2.6%, p=0.001, respectively). Multivariate regression analysis showed PCI volume did not independently predict MACCE. Conclusions: Hospital PCI volume was not found to be an independent predictor of in-hospital clinical outcomes in patients with AMI included in the 2014 K-PCI registry.

커넥티드 콘포넌트 라베링을 적용한 얼굴 영역 추출 임베디드 시스템

심명환 ( Shim Myoung-haan ),한태규 ( Tae-kyu Han ),김영섭 ( Young-seop Kim ),이상범 ( Sang-burm Rhee ) 한국정보처리학회 2005 한국정보처리학회 학술대회논문집 Vol.12 No.2

본 연구에서는 모바일 단말기를 활용할 수 있는 얼굴 영역을 추출 하는 시스템을 구현을 제안한다. 임베디드 프로세서에 커넥티드 콤포넌트 라베링을 이용하여 PDA와 핸드폰, 스마트폰에서 얼굴 영역추출이 가능한 시스템을 설계 하였다. 얼굴 영역을 추출한 결과 빠른 처리 속도와 높은 추출율을 보였다.

내시경적 역행성 담췌관조영술 시 예방적 항생제 투여의 유용성

이규택,김재준,최규완,백승운,이종균,고광철,이풍렬,이종철,성인경,심상군,김창섭,최문석,이준혁,류광현 대한소화기내시경학회 1999 Clinical Endoscopy Vol.19 No.6

Background/Aims: Prophylactic antibiotics are used in an attempt to avoid the septic complications of endoscopic retrograde cholangiopancreatography (ERCP). But, there is individual tendency to choose prophylactic antibiotics due to a lack of definite guidelines for prophylactic antibiotics. Therefore, the effectiveness of ciprofloxacin to prevent post ERCP infectious complications was evaluated. Methods: One hundred patients underwent 75 diagnostic ERCPs and 25, therapeutic ERCPs. They were classified randomly into a group of 51 prophylaxis (ciprofloxacin 200 mg i.v. 30 min before the procedure) and 49 controls. Pre- and post-ERCP blood cultures were prospectively performed and surveyed for infectious complications. Results: Sepsis was detected in 4 patients in each group (p>0.05). Two cases were related to diagnostic ERCP and the remaining six cases, therapeutic ERCP (p<0.01). Bacteremia was found in 6 cases, but only two cases (Escherichia coli, Citrobacter freundii) were clinically significant. Conclusis: The frequency of sepsis following ERCP was not significantly reduced by antibiotic prophylaxis (7.8% vs. 8.2%).

관상동맥질환 환자에서 관상동맥 중재시술 후 재협착율 및 재협착 예측인자

오석규,김남호,유남진,윤경호,안선호,박병현,이명수,심혁,이상재,김재권,이동수,배은철,박양규,정진원 圓光大學校 醫科學硏究所 2002 圓光醫科學 Vol.17 No.1

배경 : 관상동맥 중재시술 후 재협착의 발생은 아직도 해결하지 못한 중요한 문제점으로 남아있다. 이에 저자들은 경피적 관상동맥 중재시술을 받았던 환자들 중 추적관상동맥 조영술을 실시한 환자를 대상으로 재협착의 발생 빈도 및 재협착에 관여하는 인자에 대해 알아보고자 하였다. 방법 : 2000년 10월부터 2001년 12월까지 원광대학교병원에 관상동맥 질환으로 내원하여 경피적 관상동맥 중재시술을 실시했던 환자 중 추적 관상동맥 조영술을 실시했던 84명의 환자(남자 62명, 평균연령 59±10세), 110병변을 대상으로 하였다. 추적관상동맥 조영술은 평균 8.7개월(2∼22개월)에 실시하였으며, 재협착은 추적관상동맥 조영술상 50% 이상의 내경협착이 있는 경우로 정의하였다. 스텐트 삽입군과 PTCA군간의 임상적 특성, 위험인자, 관상동맥 조영술상 특성 및 재협착율을 비교하였고, 스텐트 삽입군에서 재협착과 관련된 임상적 특성과 관상동맥 조영술상 특성을 비교 분석하였다. 결과 : 대상환자의 임상적 진단은 심근경색증이 51명(61%), 불안정 협심증 28명(33%), 안정형 협심증 5명(6%) 이었으머, 병변의 위치는 좌전하행지 46병변(42%), 우관상동맥 37병변(34%), 좌회선지 27병변(24%)이었다. 추적관상동맥 조영술상전체 재협착율은 23.6%(26/110병변)였으며, 스텐트 삽입군과 PTCA군의 재협착율은 각각 23.0%(20/87병변)와 25.0%(6/23병변)로 두 군간의 의미있는 차이는 없었다(P=0.756). 스텐트 삽입후 재협착과 관련된 인자로는 당뇨병(P=0.033), 병변의 유형(P=0.021), 수정한 병변의 유형(P=0.004) 및 완전폐쇄 병변(P=0.017)이 관계하였으며, 그 외의 다른 인자들은 관계하지 않았다. 결론 : 관상동맥 질환의 치료에 있어 스텐트 삽입술은 PTCA 단독 치료보다 재협착율 감소에 유용한 치료방법임을 알 수 있었다. 스텐트 삽입술후 재협착 발생과 관련된 인자로는 당뇨병, 병변의 유형, 수정한 병변의 유형 및 완전폐쇄 병변등이 관여하였으며 향후 더 많은 환자를 대상으로 한 연구가 필요할 것으로 사료된다. Background : Restenosis remains one of major clinical problems in percutaneous coronary intervention(PCI). The objective of this study was to identify the restenosis rate after PCI and to identify clinical and angiographic factors that can predict restenosis after coronary stent placement. Methods : One hundred and ten treated lesions of 84 patients(59±10 year-old, 62 male), who underwent PCI and follow-up angiography in the Wonkang University Hospital from October 2000 to December 2001, was included. Follow-up angiography was performed at average 8.7 months(2∼22 months) after PCI. Angiographic restenosis was defined as a stenosis of over 50% diameter at follow-up coronary angiography. Clinical variables, risk factors, angiographic characteristics, and restenosis rate of the stenting group(87 lesions) were compared with that of the PTCA group(23 lesions). In the stenting group, the clinical and angiographic factors associated with restenosis after PCI was analyzed. Results : The clinical diagnosis of the subjects were myocardial infarction in 51 patients, unstable angina in 28, and stable angina in 5. The overall restenosis rate was 23.6%(26/110 lesions). The restenosis rate was 23.0%(20/87 lesions) after stent placement and 26.0%(6/23 lesions) after PTCA(p=0.756). In the stenting group, diabetes(p=0.033), lesion type(p=0.021), modified lesion type(0.004), and total occlusion(0.017) were associated with restenosis after stent placement, but other factors were not associated. Conclusion : Coronary stent placement results in a lower rate of restenosis in the treatment of the patient with coronary artery disease. Diabetes, lesion type, modified lesion type and total occlusion are significant predictors of restenosis after coronary stent placement.

Apoptotic effect of DMNQ S64 via ROS activation and NFkB inhibition in A549, human non small lung cancer cells

Yun-Hee Rhee,Min-Kyu Park,Hyo-Jung Lee,Eun-Ok Lee,Keun-Sung Lee,Bumsang Shim,Kyoo-Seok Ahn,Sung-Hoon Kim 한의병리학회 2006 대한동의병리학회 학술대회논문집 Vol.2006 No.9

건강검진 수진자에서의 담낭용종의 유병률 및 위험인자 분석

심상군(Sang Goon Shim),이규택(Kyu Taek Lee),이종균(Jong Kyun Lee),박정호(Jung Ho Park),류광현(Kwang Hyun Ryu),이풍렬(Poong Lyul Rhee),김재준(Jae Jun Kim),고광철(Kwang Cheol Koh),백승운(Seung Woon Paik),이종철(Jong Chul Rhee),최규완(K 대한내과학회 1999 대한내과학회지 Vol.57 No.6

N/A Background : Gallbladder (GB) polyps are now increasingly detected by ultrasonography. We investigated the prevalence and risk factors of GB polyps in health screening population. Methods : An ultrasonographic study of GB polyps were conducted in 35,012 subjects who received a paid health screening examination at Samsung Medical Center. Controls, twice the subjects with GB polyp, were randomly selected from the cases with normal GB. The demographic characteristics and biochemical parameters were recorded. Results : The overall prevalence of GB polyps was 2.94% (1,330/15,573). Among them, 3.63% were men, 2.09% were women. In both males and females, the prevalence was highest in their 40s. The diameter of GB polyps ranged from 2 mm to 20 mm (mean 4.5 mm). Most polyps (98.3%) were less than 10 mm in diameter. Of 1,030 subjects, 64% had a single polyp and 36% had multiple polyps. Multiple logistic regression, with reference group of body mass index (BMI, <22.5 kg/m2), showed odds ratio of 1.074 and 1.864 for BMI groups of 22.5-24.9 and 25 or more respectively. In contrast, other demographic characteristics and biochemical parameters, such as age, smoking, alcohol use, glucose, liver function tests, lipid profiles and HBsAg carriage were lack of any relation to GB polyps. Conclusions : GB polyps are not likely to be rare in Korean adults despite their low prevalence compared to other reports. The body mass index may be a risk factor for GB polyps. (Korean J Med 57:1014-1020, 1999)

다발성 관절염 실험동물 모델에서 저출력 GaAsAl 레이저 자극에 의한 소염효과

장문경,심규리,최영덕,Chang, Moon-Kyoung,Shim, Kyu-Rhee,Choi, Young-Deog 대한물리치료과학회 2002 대한물리치료과학회지 Vol.9 No.2

We designed the experiments to elucidate the anti-inflammatory effect of low power laser stimulation on acupoint or non-acupoint using arthrogenic solution induced poly arthritis animal model. In order to achieve the experimental purpose, change in body weight paw edema, pathological changes in inflammed pint and the serum interlukin-6 level were measured after arthritis induction in acupoint later stimulated group, non acupoint laser stimulated group and non treated control animal. The results were summerized as follows: 1. The consistent increase in body weight was observed in the normal animal during whole experimental period, while the induction of arthritis significantly suppressed increase in body weight from the 15 day after arthritis induction. Especially, non treated animal group showed more suppressive effect on increase in body weight as compared to that of low power laser stimulated groups (P<0.05). 2. Low power laser stimulation on acupoint (Zusanli) significantly inhibited edema in the left side paw from the 12th day after arthritis induction as compared to that of non treated animals. This suppressive effect on paw edema was maintained until the end of experiment. 3. Laser treatment on acupoint dramatically suppressed the radiological change (i.e. new bone proliferation and soft tissue swelling) caused by arthritis as compared to that of non treated group animals. 4. Low power laser treatment reduced the increase in serum interlukin-6 caused by arthritis induction to levels observed in the normal animals. In conclusion, the results of the present study demonstrated that low power laser stimulation on acupoint has potent anti-inflammatory effect on arthritis. Thus it is recommended that low power laser be used for long term treatment of arthritis induced inflammation. However, further study is necessary to clarify the possible side effect of laser treatment depending upon intensity and duration of stimulation.

한국산(韓國産) 식용(食用) 해조류(海藻類)의 성분(成分)에 관(關)한 연구(硏究) -I. 수종(數種) 식용(食用) 갈조류(褐藻類)의 구성(構成) 성분(成分)에 대(對)하여-

이인규,심상칠,조한옥,이종욱,Lee, In-Kyu,Shim, Sang-Chil,Cho, Han-Ok,Rhee, Chong-Ouk 한국응용생명화학회 1971 Applied Biological Chemistry (Appl Biol Chem) Vol.14 No.3

한국산(韓國産) 식용해조류(食用海藻類)의 구성성분(構成成分)을 조사(調査)하기 위하여 10종(種)의 식용(食用) 갈조류와 2종(種)의 비식용(非食用) 갈조류를 재료로 하여 일반화학성분(一般化學成分)과 각종 무기염류를 분석 검토하였다. 시료(試料)는 1970년(年) 10월(月) $28{\sim}30$일(日) 제주도에서 채집(採集)하였다. 1) 일반성분(一般成分) 중(中) 수분(水分)은 건물량(乾物量)의 $14{\sim}16%$를 함유하고, 조단백질은 대부분(大部分)이 16% 정도여서 육상야생 식용식물의 경우와 비슷하였다. 조지방(粗脂肪)은 $0.7{\sim}2.0%$ 정도이고, 조섬유(粗纖維)는 $3{\sim}8%$였으나 조회분(粗灰分)은 $9.17{\sim}16.89%$로 매우 높은 함량을 나타내고 있다. 환원당으로 정량한 유리 단당류는 $0.27{\sim}2.49%$를 포함하고 있다. 2) 무기염류 중에서는 Ca이 가장 많아서 $1.73{\sim}2.51%$였고, S이 그 다음으로 $1.0{\sim}1.8%$, Na 과 K이 약 1% 정도였다. Mg과 옥소(沃素)는 약 $0.1{\sim}1%$였고 미량원소에 속하는 Fe과 Zn은 약 $0.01{\sim}0.03%$, Cu와 Mn은 $0.001{\sim}0.005%$ 정도였다. 3) 식용성(食用性) 갈조류와 비식용성(非食用性)인 것 사이에 그 구성성분상(構成成分上) 특기할 차이는 없었고 더욱이 본 실험 결과만으로는 이들의 분류(分類) 내지(乃至) 계통학적(系統學的) 유연관계를 설명해 줄 수 있는 성분상의 차이는 찾아 볼 수 없었다. 4) 해조류가 식품(食品)으로서 지니는 가치는 지방 단백질 및 탄수화물의 함량보다 각종(各種) 무기염류가 다량(多量)으로 또한 다양(多樣)하게 들어 있는 점(點)에 있다고 할 것이다. In order to investigate chemical components of edible marine algae in Korea, the present work is carried out with ten edible and two non-edible species of brown algae, collected from Cheju-island during October, 28-30 in 1970. Among the general components, water content is about 14-16% to dry weight and the crude protein about 16%, which are almost similar in content compared with several non-cultivate edible land plants. The content of crude fat is about 0.7-2.0%, and that of crude fiber about 3-8%, while the content of crude ash is 9.17-16.89%. The last one is more than two times in content compared with the land plants. The reducing sugar is about 0.27-2.49% in general. On the other hand, among the minerals Ca content is the most abundant, 1.73-2.51%, and the next is S, 1.0-1.8%. Mg and I are around 0.1-1%, while K and Na are about 1% in content. Among the micro-elements, Fe and Zn are about 0.01-0.03%, and Cu and Mn 0.001-0.005% in content. There is no special significant difference in chemical components between the edible and non-edible species of brown algae. Moreover, so far as the present investigation is concerned, there can be found no significant inter-species relationship on the taxonomical or phylogenetical points of view, considering their components.