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- 저자 : S.K. Kulkarni (검색결과 30 건)
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Patil, S.S.,Patil, D.R.,Apte, S.K.,Kulkarni, M.V.,Ambekar, J.D.,Park, C.J.,Gosavi, S.W.,Kolekar, S.S.,Kale, B.B. Elsevier 2016 Applied Catalysis B Vol.190 No.-
<P>Ag3PO4 is a good photocatalyst but ubiquitously known for its photocorrosion problem during photocatalytic reaction. Therefore, stabilization of Ag3PO4 with retaining its fundamental properties has immense importance. With this motivation, we designed Ag3PO4 glass nanocomposite to resolve the problem of photocorrosion. Moreover, the effect of size quantization on photocatalytic activity has also been demonstrated by growing the cubic Ag3PO4 nanoparticles with size in the range of 3-9 nm in glass matrix via melt and quenching method. The band gap of Ag3PO4 has been tuned (2.56-2.25 eV) in glass matrix with respect to size. Considering the size tunable band gap of Ag3PO4 glass nanocomposite within visible region, it is demonstrated as a photocatalyst for hydrogen (H-2) production from copious hazardous waste H2S. The utmost H-2 production i.e. 3920.4 mu mol h(-1) g(-1) is obtained using 1 gm of Ag3PO4 glass nanocomposite powder. The apparent quantum yield for H-2 production is calculated to be 5.51% for Ag3PO4 glass nanocomposite. Interestingly, presence of plasmonic Ag was also observed in Ag3PO4 glass nanocomposite which contributes for H-2 production through enhanced light absorption, efficient charge separation and improved stability. Recycling study of sample reveals stable H-2 production efficiency and good stability of the photocatalyst. Surprisingly, catalyst can be reused many times and recovery of catalyst is possible just rinsing with distilled water. All these results demonstrate directly the feasibility of designing a new generation photocatalysts. (C) 2016 Published by Elsevier B.V.</P>
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Protective Effect of Quercetin on Alcohol Abstinence-Induced Anxiety and Convulsions
S.K. Kulkarni,D. Joshi,P.S. Naidu,A. Singh 한국식품영양과학회 2005 Journal of medicinal food Vol.8 No.3
Chronic administration of ethanol (2 g/kg, p.o.) on days 16 and its withdrawal produced an anxiogenic reac-tion in mice as assessed in the mirrored-chamber test. Daily administration of quercetin (25 or 50 mg/kg, p.o.) prior to ethanolfor 6 days prevented withdrawal-induced anxiety in mice. However, acute administration of a single dose of quercetin (50mg/kg) to animals withdrawn from ethanol, i.e., on day 7, did not prevent withdrawal-induced anxiety. Ethanol withdrawalalso induced a significant increase in the locomotor activity of mice indicating an anxiogenic response. Daily administrationof quercetin (25 or 50 mg/kg, p.o.) prior to ethanol for 6 days prevented withdrawal-induced increased locomotor activity.Ethanol withdrawal also sensitized the convulsogenic reaction to pentylenetetrazole (PTZ). A non-convulsive dose (4060mg/kg) of PTZ produced full-blown convulsions and increased mortality in ethanol-withdrawn mice. Both acute and chronicadministration of quercetin (25 or 50 mg/kg, p.o.) produced a significant protection against ethanol withdrawal-induced re-duction in PTZ threshold in mice. The result suggests the protective effect of this safe drug, quercetin, in the management ofethanol withdrawal reactions.
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EXPERIMENTAL CHARACTERISATION OF VLSI INTERCONNECTS USED IN HIGH-SPEED MULTICHIP MODULES
Kulkarni,S. Y.,Murthy,K. V. V. 대한전자공학회 1995 ICVC : International Conference on VLSI and CAD Vol.4 No.1
The cross-talk voltage generated by on-chip and off chip circuitry is one of the major considerations in IC design and package for high-speed systems. These crosstalk effects increase as a result of shorter rise times, larger chip currents, greater die dimensions and smaller spacing between the circuit components on the chips and boards. As a consequence of this the system-performance is mainly governed by the performance of interconnection system-performance. Considerable amount of work has been done theoretically to characterize such interconnection performance. However, the experimental characterisation aspects of such high-speed interconnects has received very less attention. In this paper, an effort has been made to characterise such interconnects experimentally. The results obtained from such characterisation are used to validate the theoretical results.
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Pushover analysis - result borders due to hinge formation orders
Kulkarni, Supriya R.,Narayan, K.S. Babu Techno-Press 2018 Structural monitoring and maintenance Vol.5 No.2
Performance evaluation of RC frame building by nonlinear static pushover analysis that accounts for elastic and post elastic behavior is becoming very popular as a valid decision making tool in seismic hazard resistant designs. Available literature suggests great amount of interest has shown by researchers in suggesting refinements to geometric and material modelling to bridge the gap between analytical predictions and observed performances. Notwithstanding the attempts gaps still exists. Sequence of plastic hinge formation which has great influence on pushover analysis results is an area less investigated. This paper attempts to highlight the importance of hinge sequence considerations to make analysis results more meaningful. Variation in analysis results due to different hinge sequences have been quantified, compared and bounds on analysis results have been presented.
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THERMAL AND STRUCTURAL ANALYSIS OF CALANDRIA VESSEL OF A PHWR DURING A SEVERE ACCIDENT
Kulkarni, P.P.,Prasad, S.V.,Nayak, A.K.,Vijayan, P.K. Korean Nuclear Society 2013 Nuclear Engineering and Technology Vol.45 No.4
In a postulated severe core damage accident in a PHWR, multiple failures of core cooling systems may lead to the collapse of pressure tubes and calandria tubes, which may ultimately relocate inside the calandria vessel forming a terminal debris bed. The debris bed, which may reach high temperatures due to the decay heat, is cooled by the moderator in the calandria. With time, the moderator is evaporated and after some time, a hot dry debris bed is formed. The debris bed transfers heat to the calandria vault water which acts as the ultimate heat sink. However, the questions remain: how long would the vault water be an ultimate heat sink, and what would be the failure mode of the calandria vessel if the heat sink capability of the reactor vault water is lost? In the present study, a numerical analysis is performed to evaluate the thermal loads and the stresses in the calandria vessel following the above accident scenario. The heat transfer from the molten corium pool to the surrounding is assumed to be by a combination of radiation, conduction, and convection from the calandria vessel wall to the vault water. From the temperature distribution in the vessel wall, the transient thermal loads have been evaluated. The strain rate and the vessel failure have been evaluated for the above scenario.
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Kulkarni, Sachnin A.,Sawadh, P.S.,Palei, Prakash K. Korean Chemical Society 2014 대한화학회지 Vol.58 No.1
Magnetite nanoparticles were prepared by co-precipitation method and then silica was coated onto the surface of $Fe_3O_4$ by hydrolysis of TEOS. The silica coated magnetite nanoparticles were characterized for its structural, microstructural, optical, vibrational and magnetic properties by X-ray diffraction analysis, Scanning electron microscopy, UV-visible spectroscopy, Infrared spectroscopy and Vibration sample magnetometer, respectively. XRD study confirmed the presence of $SiO_2$ on the surface of magnetite nanoparticles. SEM study indicated that with increase in TEOS content the particles become bigger and mono-disperse. It was also found that the silica coating prevents magnetic particles from aggregation and imparts excellent stability.
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Mutation analysis and characterisation of F9 gene in haemophilia- B population of India
Sujayendra Kulkarni,Rajat Hegde,Smita Hegde,Suyamindra S. Kulkarni,Suresh Hanagvadi,Kusal K. Das,Sanjeev Kolagi,Pramod B. Gai,Rudragouda Bulagouda 대한혈액학회 2021 Blood Research Vol.56 No.4
Background Hemophilia B (HB) is an X-linked bleeding disorder resulting from coagulation factor IX defects. Over 3,000 pathogenic, HB-associated mutations in the F9 gene have been identified. We aimed to investigate the role of F9 variants in 150 HB patients using sequencing technology. Methods F9 gene sequences were amplified from peripheral blood-derived DNA and sequenced on an Applied Biosystems (ABI) 3500 Sanger sequencing platform. Functional and structural predictions of mutant FIX were analyzed. Results Among 150 HB patients, 102 (68%), 30 (20%), and 18 (12%) suffered from severe, moderate, and mild HB, respectively. Genetic analysis identified 16 mutations, including 3 novel mutations. Nine mutations (7 missense and 2 stop-gain) were found to be pathogenic. Only 3 mutations (c.127C>T, c.470G>A, and c.1070G>A) were associated with different severities. While 2 mutations were associated with mild HB cases (c.304C>T and c.580A>G), 2 (c.195G>A and c.1385A>G) and 3 mutations (c.223C>T, c.1187G>A, and c.1232G>A) resulted in moderate and severe disease, respectively. Additionally, 1 mutation each was associated with mild-moderate (c.*1110A>G) and mild-severe HB disease (c.197A>T), 4 mutations were associated with moderate-severe HB cases (c.314A>G, c.198A>T, c.676C>T, and c.1094C>A). FIX concentrations were lower in the mutated group (5.5±2.5% vs. 8.0±2.5%). Novel p.E66D and p.S365 mutations were predicted to be pathogenic based on changes in FIX structure and function. Conclusion Novel single nucleotide polymorphisms (SNPs) largely contributed to the pathogenesis of HB. Our study strongly suggests that population-based genetic screening will be particularly helpful to identify risk prediction and carrier detection tools for Indian HB patients.
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Shrinivas K. Kulkarni,Pattipati S. Naidu,Amanpreet Singh 한국식품영양과학회 2003 Journal of medicinal food Vol.6 No.2
We investigated the role of oxidative stress in the pathophysiology of haloperidol (HP)-in-duced orofacial dyskinesia and evaluated the beneficial effect of Withania somnifera (Ws)root extract in the amelioration of HP-induced vacuous chewing movements (VCMs) andtongue protrusions in the rat model for TD. Rats were treated for 21 days with intraperitonealHP (1 mg/kg); on day 22, VCMs and tongue protrusions were counted during a 5-minute ob-servation period. HP-treated rats significantly developed these extrapyramidal symptoms, butcoadministration of Ws root extract (10 300 mg/kg) dose-dependent ly reduced them. Bio-chemical analysis revealed that chronic HP treatment significantly increased lipid peroxida-tion and decreased forebrain levels of glutathione and the antioxidant defense enzymes, su-peroxide dismutase (SOD) and catalase. Coadministration of Ws extract significantly reducedthe lipid peroxidation and significantly reversed the decrease in forebrain SOD and catalaselevels but had no significant effect on the HP-induced decrease in forebrain glutathione lev-els. These findings strongly suggest that oxidative stress plays a significant role in HP-in-duced orofacial dyskinesia and that Ws could be effective in preventing neuroleptic-induce dextrapyramidal side effects.107
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