濟州道 갈옷의 衛生的 特性에 關한 硏究

南潤子,洪明和 慶熙大學校 1986 論文集 Vol.15 No.-

(1) In the experiment of tensile strength(unit ㎏) between raw cotton arid Gal-ott, since raw cotton was 16.7, Gal-ott 20.7, the warp was higher by 24%. In the weft, raw cotton was 30.2 Gal-ott 42.1, thus Gal-ott was much stronger by 39.4% than raw cotton. (2) In the comparison of elongation between raw cotton and Gal-ott, raw cotton was 10.5% in the warp, Gal-ott was 18.4%, thus Gal-ott was stronger by 70% Raw cotton was 15.8% in the weft while Gal-ott was 19.7%, thus Gal-ott was higher by 24%. (3) In the thermal transmittance between raw cotton and Gal-ott, raw cotton was 24.65%, but Gal-ott 23.27, thus Gal-ott was lower. (4) The colorfastness to rubbing of Gal-ott became higher after the third washing. (5) The colorfastness to light of Gal-ott became distinctively low in proportion to the hour it was exposed to light. (6) In the colorfastness to perspiration, it was high in the acid perspiration solution, but low in the alkali perspiration solution. (7) In the colorfastness to washing, staining was high, but it was low in change in color.

전통 누비에 관한 연구

홍명화(Myung Wha Hong),남윤자(Yoon Ja Nam) 한국복식학회 2000 服飾 Vol.50 No.1

The results of this study were as follows: The quilt has been used for warmth, supporting materials, protection, religious uses, decoration and giving stability of shapes. Quilt is developed from monk`s robe of lags, and the word `nubi` is originated from `nabeui` in both Korea and Japan. Korean quilt was used mainly for warmth: Japanese one was used for warmth and supporting materials. The techniques used for traditional Korean quilt were parallel vertical hand stitches. On the other hand, Japanese traditional quilt uses various motifs of sashiko which is similar to embroidery and named by region. Korean quilt can be divided into three types by the stitch intervals: Fine quilt(Jan nubi), Medium quilt(Jung nubi) and Wide quilt(Demun nubi). Japanese quilt has been developed in east-north region, and can be grouped into sashiko, kogin and hishizashi by motifs of quilt. Korean quilt costumes are stuffed with cotton between the outer fabrics and linings, and stitched vertically on the fabrics. Main fabrics used were silk and cotton. Japanese quilt costume uses cotton yarns for stitching on flax or cotton fabrics, and main uses of the quilt costumes were working clothes of working classes. Both Korean and Japanese quilt costumes contain of family`s health, happiness and longevity. In summary, Korean quilts use two layers of fabrics and stuff them with cotton, and stitch parallel vertical lines to provide warmth. Japanese quilt are sashiko which is stitches of strand in various shapes using cotton yarns, differ by region, and are made for warmth and supporting materials.

전통 안경집의 구성적 특성

홍명화(Hong Myung-Wha) 한복문화학회 2013 韓服文化 Vol.16 No.3

This study is concerned in the constructional features of Korean traditional spectacle cases. It aims to understand the constructional properties of this everyday-use object, and thus to provide basic data for their designs necessary to create high added value. Research method is an analysis of the relics on display at museums and investigation of relevant literature, from Joseon Dynasty up to modern times. Objects of this study are limited to the cases with portable strings. This study has found that the constructional features of traditional spectacle cases differ by the opening and closing method, bridge type, materiel and manufacturing techniques. Materials used include wood, fabric, lacquer, paper, leather, fishskin, hawksbill, cows horns, metal, knit fabric, and others. Manufacturing techniques include sculpture, dyeing, embroidery, quilting, inlay, paper-weaving and knitting. They include traditional craft techniques. It was found that traditional craftsmanship of Korea has been widely employed, which resulted in appearance of a variety of applied expressive methods. Traditional spectacle cases are composed of a body, a string and an ornament. By way of inheriting and developing the unique traditional culture of Korea, we could more than anything else turn out cultural products representative of our distinctive identity in a globalized modern society, thereby contributing to create higher added values. It is only hoped that designs wherein tradition and modernity are in perfect harmony will follow, making best use of the structural features, that is, the open or close type, and the varying expressive and manufacturing techniques according to materials of traditional spectacle cases.

암환자에서 TPN투여의 적정성 평가

홍수연,민명숙,이영미,손기호,최경업,김화정,신완균,서옥경 한국병원약사회 2003 병원약사회지 Vol.20 No.4

TPN(total parenteral nutrition) not only supplies nutrition but also works as a therapeutic drug since improving patient's nutritional status causes remedy of disease. The objective of this study was to evaluate use of TPN for appropriateness in cancer patients. A retrospective study was conducted to evaluate the appropriateness of TPN in 111 hospitalized cancer patients in Samsung Medical Center from July 1, 2000 to December 31, 2001. The standard criteria published by ASHP(American Society of Health-System Pharmacists) and ASPEN(American Society of Parenteral and Enteral Nutrition) were modified and applied. The indications were appropriate in 82.9% of 111 cancer patients and in 13 patients(11.7%) TPN lasted for ≤5 days. All the laboratory monitoring before starting TPN was done appropriately in over 90% of patients except for Ca^(2+), PO₄^(3-), Mg^(2+), glucose tolerance, lipid tolerance, hemorrhagic incidence, total protein and prealbumin. The monitoring during TPN administration was done approrpiately in over 90% of patients except for electrolyte balance, renal function, glucose tolerance, lipid tolerance, hemorrhagic incidence and prealbumin. For the assessment of TPN formula, non-protein calorie was appropriate in 83.8%, protein in 98.2%, and lipid in 78.4% of the patients. For administration method, glucose tapering was done appropriately only in 28.8%. For the nutritional prognosis assessment, increase in BUN was statistically significant. Patients with elevated liver enzymes over 2 times the upper limit of normal values were less than 18%. Hyperglycemia occurred in 15%. The abnormalities in K^(+) and Mg^(2+) were not found, but Na^(+) and PO₄^(3-) imbalances were found in less than 6%. In conclusion, the indicators for TPN use in cancer patients were measured appropriately in majority of monitoring indicators. This probably was due to an active role of clinical pharmacists in assessing and monitoring TPN therapy.

Changes in Sexual Organs during Pollination in Chrysanthemum

Myung Syun Shim,Myung Wha Hong,Jin Hee Lim,Seong Youl Choi,Hak Ki Shin,Ki Sun Kim 한국원예학회 2006 Horticulture, Environment, and Biotechnology Vol.47 No.6

The present research was undertaken to observe the changes in sexual organs during pollination in chrysanthemum. Stamens began to grow in the narrow disc florets first and thereafter pistils grew and pushed the pollen grains from the base so that the pollen adhered to the stigma. If the pistils were not pollinated with the pollen of other cultivars, no seeds could be produced. Therefore, such development was beneficial to explain the self-incompatibility characteristics of chrysanthemum. When the chrysanthemum flowers of several cultivars were self-pollinated and investigated one day later, there were no shriveled pistils and no seed production in the flowers in the end. In 'Lineker Salmon' and 'Lineker White', many pistils of the cross-pollinated flowers were shriveled into the disc florets and produced some seeds. Consequently, the non-shriveling pistil in the self-pollinated flowers can be used as an early evidence for the incompatibility of chrysanthemum. Chrysanthemums are already known to show sporophytic self-incompatibility, and it was confirmed by the observations of stigmas with no adhered pollen grains or inhibited pollen tubes with no penetration in this experiment. It was possible to use the pollens after long storage period over 2 months at low temperatures like -75 and -20℃. The self-incompatibility characteristics in chrysanthemums can be explained by the several changes of sexual organs.

백서패혈증 모델에서 Melatonin 항산화 효과에 관한 연구

홍성화,이상목,조용호,고영관,이석환,고석환,김윤화,윤충,김명천,백형환,변영훈 대한외상학회 1999 大韓外傷學會誌 Vol.12 No.1

Despite the major advances in the management of critically ill patients, septic shock and ensuing MODS continue to be the most common causes of death in the surgical intensive care unit. Endotoxin in sepsis stimulates macrophages and immune cells, and these stimulated cells secrete multiple cytokines such as TNF-α, IL-1β, and INFγ and these in turn stimulate polymorphonuclear leukocytes(PMNs). The stimulated PMNs easily adhere to the vascular endothelial wall and secrete free oxygen radicals, which destroy cell function by cellular membrane lipid peroxidation. The consecutive reactions are responsible for the pathophysiologic consequences of septic shock. Melatonin, the major endocrine product of the pineal gland, was found to be an effective free radical scavenger and antioxidant and may stimulate some important antioxidant enzymes, i.e. superoxide dismutase, glutathione peroxidase and glutathione reductase. This study focused on the effect of melatonin in rat sepsis model by using the Chaudry method, cecal ligation and puncture(CLP) that the cecum was ligated with 3-0 silk and punctured with 21-gauge needle twice. Rats were divided into 3 groups: the control group(Sham operation group), the ethanol-administered group, and the melatonin-administered group. There were eight rats in each group. Melatonin 10mg/kg was administered subcutaneously every one hour. Parameters to be checked were tumor necrosis factor(TNF-α) and IL-1β in rat serum and malondialdehyde(MDA), xanthine oxidase, and histopathologic findings in the lung and the liver. Each parameter was obtained 2, 4, 6 and 10 hours after operation by sacrificing the rats at that time. The concentration of TNF-α increased persistently in sepsis induced groups and was significantly lower (p$lt;0.05) 2 hours after operation in the melatonin-administered group (39.5 ±12.1pg/ml) than in the ethanol-administered group (82.0 ±9.1pg/ml) and was lower 4, 6, and 10 hours after operation in the melatonin-administered group, but this last data was not statistically significant. The concentration of IL-1β in the melatonin-administered group was lower than that of the ethanol- administered group, but this was not statistically significant. The concentration of MDA in the lung in the ethanol-administered and the melatonin-adminis- tered group at 10 hours after operation was 199.3 ±51.1 and 56.5 ±23.3 pmol/mg protein, respectively, which indicates a statisticaUy significant difference(ANOVA test, p$lt;0.001). The concentration of MDA in the liver 6 and 10 hours after operation in the ethanol-administered and melatonin-administemd groups was 260.6 ±38.5, 291.2 ±65.1 and 172.6 ±25.3, 148 ±9.1 pmoVmg protein, respectively, showing a statistically significant difference. There was more of an elevation in the concentration of xanthine oxidase in the lung and the liver of the ethanol- administered group, but it was statistically insignificant. Histopathologic findings of the lung in the melatonin-administered group 6 hours after operation showed intact alveoli and minimal infiltration of polymorphonuclear leukocytes in alveoli and interstitial thickening with many PMNs infiltrations and those of the liver in the melatonin-administered group showed less infiltration of PMNs in the portal space. In conclusion, melatonin was considered to have an antioxidant activity, a scavenging effect on free oxygen radical, and an inhibitory activity for an infiltration to the lung and the liver, especially in the early septic period. Further studies on the effect of a late septic period and the therapeutic dose of melatonin are needed.

정상과 갑상선 종양조직에서 사람 IGF-I 유전자의 발현

홍성화,김진우,고석환,최영길,김영설,김광원,양인명,우정택,김성운,김덕윤,장현하,박상미 대한내분비학회 1993 Endocrinology and metabolism Vol.8 No.4

Many of the growth-promoting properties of growth hormone (GH) are mediated by insulin-like growth factor-I (KGF-I), a highly conserved circulation 70-amino ackd peptide. Recent studies have shown that multiple mechanisms influence IGF-I gene expression, including trascription from two pormoters, alternative RNA splicing and variable polyadenylation. In thyroid tissue, thyroid stimulating hormone (TSH) and TGF-I are the most possible candidates for follicular cell proliferation and hypertrophy. Actually IGF-I had autocrine and paracrine effect for tissue growing. We prepared thyroid tumor tissue mRNAs using single step method for detecting IGF-I levels according to different tissue, I, e, thyroid adenoma or papillary thyroid carcinoma. We used Northern blot analysis for IGF-I mRNA and Rnase protection assay (RPA) for IGF-I transcription start sites. For Northern blot, we used whole human IGF-I cDNA as a DNA probe and for RPA, we used IGF-I exon 1 containing noncoding promoter 1 as a riboprobe. We got good RNA bands from Northern blot analysis around 1 kb(IGF-I A) and 7.5 kb(IGF-I B) region. To clarify the amount of both IGF-IA and IB mRNAs, we measured autoradinographied signal of IGF-a mRNA's bands using densitometer. In IGF-IA signals, there's no change among liver and thyroid tissues, but in case of IGF-IB mRNA bands, thd signal was markedly increased in thyroid carcinoma tissues than that of normal thyroid tissue (85% vs 14%). In the study of RPA, aoo thyroid tissues used the same transcription start sites as those of liver's. We concluded that that this different regulation of IGF-I mRNA was originated from tissue specificity. That meant some tissue specific transcription factors were related to tissue IGF-I -Sung Woon Kim, et al. : Human IGF-I Gene Expression in Normal and Thyroid Tumor Tissues- expression (J Kor Soc Endocrinol 8: 414~421, 1993).

Melatonin 의 소장 허혈 - 재관류 후 발생하는 급성 폐손상에 대한 보호작용

홍성화,이성은,이상목,고영관,이기형,김명천,백형환 대한외상학회 2000 大韓外傷學會誌 Vol.13 No.2

Background: Melatonin, the major endocrine product of the pineal gland, was found to be an effective free-radical scavenger and antioxidant and may stimulate some important antioxidant enzymes such as superoxide dismutase, glutathione peroxidase, and glutathione reductase. Our study focused on the effect of melatonin on acute lung injury followed by intestinal ischemia-reperfusion. Methods: Intestinal ischemia-reperfusion injury was induced in rats by clamping the superior mesenteric artery for 30 minutes. Thereafter, the experimental group was administered melatonin (10 mg/kg) intraperitoneally, and the control group received saline and ethanol. At 20 minutes, 60 minutes, and 120 minutes, pulmonary histopathological features were assessed as follows: 1) The pulmonary histological assessment was based on interstitial PMNs and the lung (alveolar) injury score, and 2) the alveolar microvascular permeability assessment was based on the wet-weight to dry-weight ratio and the lipid peroxidation activity (malondialdehyde, MDA), 3) in addition, the serum cytokines TNF-αand IL-1 βwere determined. Results: The control group demonstrated severe pulmonary parenchymal damage, as opposed to slight damage in the experimental group. 1) The number of sequestered neutrophils were significantly higher in the control group at 120 minutes (123.33±26.25/10HPFs) than in the mela-tonin-treated group (48.40±4.50/10HPFs) (p$lt;0.01). The lung injury score was 2.00±0.50 in the melatonin group at 120 minutes and 3.50±0.50 in the saline group (p$lt;0.005). 2) In the melatonin group at 120 minutes, the wet-weight to dry-weight ratio was 4.27±0.15, and in the saline group, this ratio was 4.56±0.17 (p$lt;0.05). A slight difference was found between the ischemia-reperfusion control group and the experimental group at 120 minutes regarding the lipid peroxidation activity (malondialdehyde) (0.55±0.10pmol/mg and 0.39±0.39pmol/mg, p$lt;0.05). 3) The serosal levels of tumor necrosis factor-αand interleukin-1 βwere equally increased in the control group and in the melatonin group at 120 minutes (TNF: 41.16±9.61pg/ml and 20.94 ±5.48pg/ml (p$lt;0.01); IL-1 β: 491.51±151.91pg/ml and 41.16±9.61pg/ml (p$lt;0.05)). Conclusion: Melatonin attenuated acute lung injury followed by intesinal ischemia-reperfusion. This may be accomplished by inhibiting oxygen free radicals and priming PMN sequestration. Thus, melatonin can be used as a treatment modality for acute lung injury.

외상성 비장 손상 5 2예의 임상적 고찰

홍성화,이상목,고영관,오수명,장연수 대한외상학회 1999 大韓外傷學會誌 Vol.12 No.2

Backgrounds : A total splenectomy was considered as the standard method to management of splenic injury. However, recently, splenic preservation has been emphasized because of the spleen ’s important immunologic function, especially in the young. This study was conducted to evaluate the safety and the indications of non-operative management of traumatic splenic injury. Methods : The medical records of 52 patients who were managed for traumatic splenic injury between Jan. 1, 1990, and Jun. 30, 1999, were evaluated. The clinical manifestations, the mecha-nism of injury, the diagnostic method, the grade of injury, the initial management, the initial treatment mode, treatment course, and complications were investigated. Results : Thirty(30) patients were initially treated medically with transfusions and intensive monitoring. A delayed operation was required in 9 patients (30%) who suffered a severe splenic injury more than grade III. Twenty-one(21) of the 30 patients (70%) who suffered a splenic injury less than grade III were successfully managed non-operatively. Nineteen(19) of the 22 patients (86%) who required an initial operation suffered a severe splenic injury more than grade III. There were differences between the non-operative and the operative groups in transfusion amount (1.1 vs 6.5 pints) and in hospital stay (14.8 vs 30.9 days). Conclusions : Non-opeartive management of traumatic splenic injury will be successful in patients who are hemodynamically stable with adequate resuscitation and a small amount of transfusion and who have suffered injuries below grade III.

원저 : 복강경 담낭절제술이 이산화탄소 주입에 따른 활력 징후와 환기 변화 ( Original Article : Changes of Vital Signs and Ventllation after Carbon Dioxide Insufflation for Laparoscopic Cholecystectomy )

강화자(Wha Ja Kang),신옥영(Ok Young Shin),이상목(Sang Mok Lee),유재욱(Jae Wook Yoo),김건식(Kun Sik Kim),홍성화(Seong Wha Hong),최중명(Joong Myung Choi),최봉근(Bong Keun Choi),신광일(Kwang Ill Shin) 경희대학교 경희의료원 1998 慶熙醫學 Vol.14 No.1