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송은석,이해혁,김태희,김정식,남계현,이권해,고은석 순천향의학연구소 2004 Journal of Soonchunhyang Medical Science Vol.10 No.2
Prolapse of the fallopian tube into the vaginal vault after hysterectomy is a rare complication. Since most of cases may resolve before detection or remain undiagnosed, the exact incidence is still unknown. Though most common sign of tubal prolapse is tender friable tissue in vaginal cuff, with the simptoms of lower abdominal pain, dysparenunia, vaginal discharge, or postcoital spotting. The definitive diagnosis should be confirmed histologically Recently, we experienced a case of fallopian tube prolapse after abdominal hysterectomy in a 41-year-old woman and report with a brief review of the literature.
조혈모세포이식 환자에서 침습성 진균 감염에 대한 Micafungin의 예방 효과 및 안전성
김시현,이동건,최수미,권재철,박선희,최정현,유진홍,이성은,조병식,김유진,이석,김희제,민창기,조석구,김동욱,이종욱,민우성,박종원 대한감염학회 2010 감염과 화학요법 Vol.42 No.3
Background: Micafungin, a potent inhibitor of 1,3-β-D-glucan synthase, is a novel antifungal agent of the echinocandin class. In vitro study showed that micafungin was effective against Aspergillus species as well as Candida species, but clinical data on the prophylactic efficacy against invasive fungal infections (IFIs) other than candidiasis are still lacking. Materials and Methods: We identified 60 consecutive adult hematopoietic stem cell transplantation (HSCT) recipients who received at least 3 doses of micafungin during neutropenic period. Micafungin was started as an alternative in patients who were intolerant or had adverse events (AEs) to primary prophylactic antifungal agents. We retrospectively reviewed the medical records and analyzed the efficacy and safety of micafungin for prophylaxis against IFIs. Results: The patients either had autologous (n=9) or allogeneic (n=51: 1 syngeneic, 24 sibling, 26 unrelated donor) HSCT. Itraconazole oral solution (n=58) was the most frequently used first line antifungal agent for prophylaxis and was administered for median 11 days. The most frequent cause of switch to micafungin was vomiting (n=42). The duration of neutropenia and micafungin administration was median 13 and 12 days, respectively. A successful outcome was achieved in 45 (75%) patients. Empirical antifungal therapy was initiated in 13 (22%) patients. There were 2 cases (3.3%) of breakthrough fungal infections which comprised a probable invasive pulmonary aspergillosis and a possible invasive fungal sinusitis. There was no case of invasive candidiasis. A total of 53 (88%) patients experienced at least one AE regardless of causality during micafungin administration. The most frequent AEs were hypokalemia, vomiting, diarrhea, and elevated serum aspartate aminotransferase or alanine aminotransferase. Among the aforementioned AEs, only 1 case of diarrhea could be classified as a probable relation with micafungin when causality was assessed. There was no AEs that caused discontinuation of micafungin. Conclusions: Micafungin seems to be a safe and effective agent for prophylaxis of IFIs including aspergillosis as well as candidiasis in HSCT recipients. However, further large, prospective, and randomized comparative studies are warranted for aspergillosis.
김희연,홍진환,박혜경,한상배,박종석,이은주,이정성,송경희,최은희,최영준,소경아,성영제,이주엽 식품의약품안전청 2000 식품의약품안전청 연보 Vol.4 No.-
본 연구는 분말상 원료(전분, 대두분)의 저장유통시 품질변화를 건전성과 안전성 측면에서 검토하여 식품의 기준 ·규격 설정f.」 합지적으로 반영하고자 하였다. 전분과 패두분의 이물을 검사하고, 2종 대두분(중국산, 미국산)을 ?0일간 IS'c와 30t에 저장하면서 성상, 수분, 산가, 과산화물가, 지방산 조성,아플라톡신 BB의 생성여부를 분석하였다. 중국산 대두분 30'』 저장군에서 50일 이후 곰팡이가 발생한 것 이외에 모든 시료에서 양호한 성상을 나타내었고, 전분과 대두닥 모든 시료에서 이물은 검출되지 않았다. 산가는 중국산과 미국산 시료간에 편차를 보여 증국산 30"C, 50일 저장시료에서 약 10배끙도 증가하였고, 과산화물가는 저장 90일후 15'E 저장군은 약 2.3배, 30'c 저장군은 3배정도 증가하였다. 대두분의 주요 지방산은 linoleic acidf18. 2), oleic acid(18 : 1), palmitic acid(16 : 0)이었으며, 3개월 저장에 따른 지방산 함량의 변화는 미미하였다. 아플라톡신 B₁은 모든 시료에서 검출되지 않았다. The objective of this study was to investigate auality changes of type raw materials(starch, soy flour) during various storage conditions. Starchflour(source of China, U.S.A) were slfred under two temperature(15'C, 30'c) forSensory evaluation, (o.reign material test, moisture content, acid value, peroxide ualue,composition, aflatorin Bi were analyzed. China soy flour(stor·ed 30'f) was contaminated by fungj on 50 days. Except for soy flour contardnated by fungi, sensory characteristics were not changed and foreign mater;als were notdetected. Acid value of China soy flour(stored at 30'C, 90 days) was about 10 times higherlevel before storage and acid value was more influenced by source(China, USA). Peroxide valuewas in proportion with the storage period slightly. The major fatty acid of soy flour waslinoleic acid(18 . 2), an(3 the change of fatty acid composition was not observed. Aflatoxlrl Blwas not detected.
횡문근융해증과 경한 신손상을 동반한 급성 A형 간염 1예
조규민,김창욱,성현진,허준,전부석,이종환,심은희,이석종,이창돈 영남대학교 의과대학 2012 Yeungnam University Journal of Medicine Vol.29 No.1
A 48-year-old male visited the emergency room of the authors’ hospital due to nausea, vomiting, and myalgia for four days. Acute hepatitis A was identified from the serologic marker of the hepatitis A virus. Mild elevation of the serum creatinine and creatinine phosphokinase(CPK) suggested rhabomyolysis, which was confirmed with the serum aldolase, myoglobin, and urine myoglobin. With supportive care, both the liver and renal func- tions were recovered gradually and fully. This case shows that rhabdomyolysis can be one of the mechanisms of renal complication in cases of acute symptomatic hepatitis A.
이윤희,안준모,김태성,박은희,정집광,이석민,이해혁 순천향의학연구소 2002 Journal of Soonchunhyang Medical Science Vol.8 No.1
Object: To compare pregnancy outcome between term pregnancy and postterm pregnancy. Method: A clinical observation has been made on 60 cases of postterm pregnancies out of 64 cases delivered at the Dept. of Obstetrics & Gynecology, Soonchunhyang University from January 1, 1997 to May 31, 2002. 100 cases of full term deliveries of 37 to 42 gestational weeks conducted in same period were used as the control group for this study. We analyzed their cesarean section rate, fetal weight, placental weight, meconium stain, perinatal morbidity. The statistical significance was defined as P<0.05. Result: The following results were obtained 1. The incidence of postterm pregnancy was 1.34%. 2. The cesarean delivery rate in postterm group(51.7%) was significantly higher than control group(26%). 3. The incidence of large fetus (weight over 4,000gm) in the postterm group(21.7%) was higher than control group(2%). 4. The weight of placenta was 757g and 706g in the postterm group and control group respectively. 5. 1, 5 minute Apgar score lower in the postterm group than control group. Conclusion : To decrease perinatal morbidity and cesarean rate at 42 or more weeks gestation, appropriate labor induction and twice weekly biophysical profile and USF(AI, Doppler) may be indicated.
이특구,권순정,오은진,김상길,김석준,김노석 한국의료복지시설학회 2006 의료·복지 건축 Vol.12 No.2
The purpose of this Guideline is to provide basic standardization basis for planning and designing of the dwellings so that elderly may live, either with their family or independently, an independently comfortable life style. Dwelling facility is defined as a physical area where important activities of daily life are conducted by a person/people and is also the focal place of a family. Therefore, the Guideline classifies the areas where daily activities are conducted by type of such activities and provides standards to countermeasure for natural physical disabilities of the elders.
"가변적 Complex Space" 개념을 활용한 도시형 교회건축 : 도시화 사회에 개방되는 복합 교회공간의 가변성 획들을 위한 제언
이은석,조용일 경희대학교 디자인연구원 2005 예술· 디자인학연구 Vol.8 No.1
The church is providing the spaces, which are shared with citizens because of the mission of coming true the vision, which changes the world through engaging in Christian mission works and religious services. However, the space is very small and irrational to use so there are lots of restriction to be acted as various cultural demands. Therefore, this study suggests "Flexible Complex Space", which is re-arranged based on time and usage. Through the spaces are connected flexibly each other, the church is able to take various cultural demands of citizens' and traditional functions of church at the same time. As a result, we can expect that the church is able to acquire rich spaces, which have adaptability and take various functions.
이은석,嘉納成男 대한건축학회 2003 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.23 No.1
The purpose of this study is to analyze the actual conditions of the labour management is steel construction in Japan. The study has been performed by job site research and site observation. On this paper I studied the present situation in the job site and to propose man-hour conditions in steel construction. The result of this study are as follows: 1. About 20% of the whole-time working is consists of over-time working. 2. The working time of Erection & Fit-up bolting worker is changes by number of member rather than steel weight. 3. The working time of Final tightening worker is strongly relate with the number of final tightening bolts. This is the result of the stable working-posture and the standard procedure. 4. From 164 to 214 sets of final tightening bolts can be tighten by 8-hour working/day.
이은섭,서성석 釜山 大學校 經營 經濟 硏究所 1999 經營 經濟 硏究 Vol.18 No.1
1978년 함부르크규칙의 제정을 전후하여 함부르크규칙이 이중보험에 미치는 영향과 관련한 논의가 심각하게 이루어진 이래 지난 20여년간의 논의를 요약해 보면 다음과 같다. 즉 동규칙의 지지자들에 따르면 함부르크규칙의 운송인에 대한 추정과일책임주의 적용이 해운기업의 효율적인 위험관리의 실행 및 운송물건에 대한 주의정도를 높임으로써 사고의 발생을 감소시켜 이중보험 및 전체적인 보험비용을 감소시킬 것이라 한다. 이에 대한 반대론자 등에 따르면 함부르크규칙의 규정은 헤이그나 헤이그-비스비규칙의 그것보다 애매하기 때문에 해석을 둘러싼 소송비용을 증가시키고, 운송인에 의한 책임보험에로의 위험의 전가는 이중보험문제를 더욱 악화시켜 전체적인 보험비용을 증가시킬 것이라 한다. 이중보험과 관련한 함부르크규칙의 평가는 객관적으로 신뢰할만한 실증분석을 통하여 최종적으로 이루어질 수 있겠으나 현재의 상황으로는 이 분석을 위한 자료의 확보가 불가능하다. 이러한 한계점을 염두에 두고 본 논문에서는 동 규칙의 해석을 통하여 결론을 내리고 있다. 함부르크규칙의 해석론적 평가를 한 결과, 단기적으로는 동규칙이 이중보험문제에 대하여 특이할만한 영향을 미칠 것으로 보이지 않으며 결국 함부르크규칙이 지향하는 이중보험문제와 관련한 이상과 현실 사이에는 상당한 괴리가 있음을 발견하였다.