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Protective Effects of N-acetylcystenine and Selenium against Doxorubicin Toxicity in Rats
Yeo-sung Yoon,Sun-don Kim,Min-hye Lee,Heung-shik S.Lee,In-se Lee,Je-kyung Sung,Eun-sung Park 대한수의학회 2003 Journal of Veterinary Science Vol.4 No.2
Effects of N-acetylcysteine and Selenium against Doxorubicin Toxicity in RatsEun-sung Park, Sun-don Kim1, Min-hye Lee, Heung-shik S. Lee, In-se Lee, Je-kyung Sung and Yeo-sung Yoon*
"덕은 가르쳐질 수 있는가?"라는 물음의 도덕교육적 함의
김상돈 ( Sang Don Kim ) 한국윤리교육학회 2009 윤리교육연구 Vol.0 No.20
소크라테스는 『프로타고라스』와 『메논』에서 "덕은 가르쳐질 수 있는가?"라는 물음을 제시한다. 프로타고라스와 메논은 미묘한 차이가 있기는 하지만 모두 덕은 가르쳐질 수 있다고 주장한다. 하지만 소크라테스는 덕의 교육가능성과 덕의 지식가능성을 논리적으로 연결시키면서 만약 프로타고라스와 메논이 덕의 지식가능성을 입증하지 못한다면 그들은 부당 전제의 오류를 범하게 되는 것임을 주장한다. 왜냐하면 덕의 교육가능성은 덕의 지식가능성에 의존하기 때문이다. 덕의 지식가능성에 대한 논의는 "덕이란 무엇인가?"라는 물음에 관한 논쟁으로 이어진다. 그러나 두 대화편 모두에서 덕의 본질에 대한 최종적인 결론은 발견되지 않는다. 따라서 덕의 교육가능성 역시 미해결의 과제로 남게 된다. 소피스트의 상대주의적 관점을 비판하고 이성에 근거한 객관적인 지식을 추구한 것으로 알려진 소크라테스가 덕의 지식가능성과 교육가능성에 대해 확신하지 않았다는 점은 다소 의아한 것이다. 그렇다면 프로타고라스, 메논과의 논쟁에서 보여준 소크라테스의 의구심은 어떤 의미로 해석될 수 있는가? 본 논문은 덕의 교육가능성에 대한 물음과 논쟁을 분석하여 그것에 담긴 도덕교육적 함의를 탐색한다. This study is focused on Socratic question, "Can be virtue teachable", in Protagoras and Meno. In Protagoras, Protagoras insists that he can teach virtue, in particular, civic virtue, and he know what it is. But Socrates presents some questions to him. According to Socrates, we cannot have a conviction about the possibility, if we don`t have the knowledge about what virtue is. Similarly in Meno, Meno also ask a question to Socrates. The teachability of virtue and the possibility as knowledge of virtue are correlated. Socrates examines two theses. But the conclusion is disappointed. Socrates still open the question those two possibilities. This means that he, too, has not a cogent argument on what virtue is. Socrates`s hesitation shows a lot of implications about moral education. Can we teach morals? What is the moral that we intend to teach. Is it the same as Socratic virtue? Or, Is it different with ancient Greek virtue. Greek, arete, can it be interpreted as virtue, modern language? We can find the answer about these questions, by distinguishing and moral. Virtue can be totally reduced into moral. It has some different logical structure. Here, we can find the true meaning of virtue ethics. In moral education, moral virtue and moral principle or moral rule have competed each other. Nevertheless, without principle, virtue cannot be justified as contents of moral education, because teaching is possible by principle. Moral principle, moral rule, and moral knowledge cannot be separated in concept. Contrarily, moral knowledge with virtue is ineffective in moral education.
장이간 이뇨제 남용중인 특발성 또는 자가획득 부종간의 병태생리의 차이
민경환(Kyung Hwan Min),김호중(Ho Jung Kim),유준호(Jun Ho Ryu),한상웅(Sang Woong Han),강석우(Seok Woo Kang),문중돈(Jung Don Mun) 대한신장학회 2000 Kidney Research and Clinical Practice Vol.19 No.1
N/A Patients suffering from idiopathic or self-induced edema are uniformly characterized by chronic use of furosemide, which leads to vicious cycle of edema. Among chronic furosemide users who don't have any other specific edema forming diseases, 9 patients from the outpatient clinic(OC) and 6 patients examined at the emergency room(ER) used it mainly for weight reduction and for cyclical edema, respectively. All of the ER group patients were presented with severe hypokalemia(2.04±0.2mEq/L; range 1.3 to 2.7 mEq/L) and alkalosis(748±0.01; range 7.44 to 7.51) but none from the OC group showed such results. Other baseline parameters including Plasma renin activity(PRA) and aldosterone level on recumbency, and FEn₂were similar in both groups. In contrast, daily working hours(6.1±0.5 vs 10±0.6hr, p<0.01), average body weight gain between AM and PM(0.4±0.1 vs 0.9±0.lkg, p<0.01), peak weight gain interval(9±0.8 vs 5±0.1day, p<0.05), PRA(7.6±1.5 vs 23.5±7.2ng/ml/h, p<0.05) and aldosterone level(22.1±4.2 vs 64.8±10.4 ng/dl, p<0.01) on ambulation, and FEk. on normokalemia(ll±2A vs 36±7.7%, p<0.01) were statistically different between the two groups. In comparison to the OC group, both the amout of urine(617±39 vs 358±26ml, p<0.01) and the percent change of PRA(-14±4 vs -3±2%, p<0.05) and al-dosterone level(-17±5 vs -4±3%, p<0.05) after saline loading(lL over 1hr, IV) following ambulation were smaller in the Elt group. Moat of the ER group patients(5/6) required aldosterone antagonist (spironolactone) added to K(+) supplement, but all of the OC group patients were managed to maintain an edema-free status with conservative treatment. In conclusion, patients with idiopathic edema seem to have more fluid transudation out of intravascular space during orthostasis with a prominent degree of deranged renin-aldosterone axis and K(+) metabolism than those with self-induced edema.
Morphological Development of Embryo, Larvae and Juvenile in Yellowtail Kingfish, Seriola lalandi
Sang Geun Yang,Sang Woo Hur,Seung Cheol Ji,Sang Gu Lim,Bong Seok Kim,Minhwan Jeong,Chi Hoon Lee,Young-Don Lee 한국발생생물학회 2016 발생과 생식 Vol.20 No.2
This study monitored the morphological development of embryo, larvae and juvenile yellowtail kingfish, Seriola lalandi, for their aquaculture. The fertilized eggs obtained by natural spawning were spherical shape and buoyant. Fertilized eggs were transparent and had one oil globule in the yolk, with an egg diameter of 1.35 ± 0.04 mm and an oil globule diameter of 0.32 ± 0.02 mm. The fertilized eggs hatched 67–75 h after fertilization in water at 20 ± 0.5°C. The total length (TL) of the hatched larvae was 3.62 ± 0.16 mm. During hatching, the larvae, with their mouth and anus not yet opened. The yolk was completely absorbed 3 days after hatching (DAH), while the TL of post-larvae was 4.72 ± 0.07 mm. At 40 DAH, the juveniles had grown to 30.44 ± 4.07 mm in TL, body depth increased, the body color changed to a black, yellow, and light gray-blue color, and 3–4 vertical stripes appeared. At 45 DAH, the juveniles were 38.67 ± 5.65 mm in TL and 10.10 ± 0.94 mm in body depth. The fish were green with a light orange color, with 7 faint green-brown stripes on the sides of their body. At 87 DAH, the juveniles had grown to 236.11 mm in TL, 217.68 mm in fork length, and 136.5 g in weight. The fish resembled their adult form, with a light yellow-green body color, loss of the pattern on the sides of their body, and a yellow coloration at the tip of the caudal fin.
Prototype Development for the GMT FSM Secondary - Off-axis Aspheric Mirror Fabrication -
Kim, Young-Soo,Kim, Jihun,Song, Je Heon,Cho, Myung,Yang, Ho-Soon,Lee, Joohyung,Kim, Ho-Sang,Lee, Kyoung-Don,Ahn, Hyo-Sung,Park, Won Hyun The Korean Space Science Society 2014 Journal of Astronomy and Space Sciences Vol.31 No.4
A prototype of the GMT FSM has been developed to acquire and to enhance the key technology - mirror fabrication and tip-tilt actuation. The ellipsoidal off-axis mirror has been designed, analyzed, and fabricated from light-weighting to grinding, polishing, and figuring of the mirror surface. The mirror was tested by using an interferometer together with CGHs, which revealed the surface error of 13.7 nm rms in the diameter of 1030 mm. The SCOTS test was employed to independently validate the test results. It measured the surface error to be 17.4 nm rms in the diameter of 1010 mm. Both tests show the optical surface of the FSMP mirror within the required value of 20 nm rms surface error.
Kim Eun-Young,Bu Sang Don 한국물리학회 2020 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.77 No.12
In this study, Bi4-xNdxTi3O12 (BNdT), in which neodymium is substituted into Bi4Ti3O12 (BiT) with a bismuth layer-structured ferroelectrics (BLSFs) structure, was deposited on a Pt/Ti/SiO2/Si substrate by using pulsed laser deposition (PLD). The BNdT film is known to exhibit structural and electrical anisotropy with the reported maximum spontaneous polarization (Ps) along the a axis (~55 μC/cm2) and the c axis (~5 μC/cm2). The ability of BNdT to control the structural change with growth orientation is key to its enhanced properties. In a PLD system, a few important factors, such as deposition temperature, oxygen pressure, and energy fluence, are responsible for the structural variation. We aimed to enhance the structural properties of polycrystalline BNdT film, so we investigated the change in the orientation of BNdT film according to PLD deposition conditions. To identify the mechanism of structural change according to deposition conditions, we used X-ray diffraction to analyze the film's orientation and to calculate the lattice constants and the crystallite size. We also used field emission scanning electron microscopy (FE-SEM) to assess the surface morphology and the grain shape of the BNdT films.