Therapeutic Effect of Autologous Activated Platelet-rich Plasma Therapy on Mid-dermal to Full-thickness Burns: A Case Series

Karina Karina,Krista Ekaputri,Johannes Albert Biben,Pritha Hadi,Hubert Andrew,Patricia Marcellina Sadikin 대한성형외과학회 2022 Archives of Plastic Surgery Vol.49 No.3

Although modern medicine hasmade great strides in the management of burn injuries, associated complications such as pain, infection, dyspigmentation, and scarring have yet to be fully dealt with. Although skin grafting and meshing are routinely performed on burn patients, this method poses a risk for adverse effects. Activated autologous platelet-rich plasma (aaPRP), which is increasingly used in the field of plastic surgery, contains growth factors beneficial for wound regeneration. Seven cases of burns with varying severity and conditions that were treated with intralesional subcutaneous injection and intravenous aaPRP are presented and discussed herein. This case series indicates that subcutaneous and intravenous aaPRP is a safe procedure with the potential to be an alternative when skin grafting cannot be done or as an adjunct treatment to skin grafting.

The Goldilocks technique: An alternative method to construct a breast mound after prosthetic breast reconstruction failure

Karina Jaikel Zavala,Jin Geun Kwon,한현호,Eun Key Kim,Jin Sup Eom 대한성형외과학회 2019 Archives of Plastic Surgery Vol.46 No.5

The Goldilocks technique for breast reconstruction utilizes redundant mastectomy flap tissue to construct a breast mound. This technique is suitable for women who decline, or are poor candidates for, traditional postmastectomy reconstruction. Moreover, this technique can be applied in secondary operations after the failure of initial reconstruction efforts. A 74-yearold patient underwent the Goldilocks procedure after reconstruction failure with an implant and acellular dermal matrix. At her 6-month follow-up, the cosmetic outcome of the procedure was satisfactory, and no complications were noted. Therefore, the Goldilocks procedure is a safe alternative to reconstruct breast mounds following reconstruction failure, especially in obese patients.

Poster Session : PS 0074 ; Cardiology : The Angiogenesis in Patients with Chronic Heart Failure and Angiographically Signifi cant Coronary Artery Diseases: Circulating Endothelial Progenitor Cells, Growth Factors and Cytokines

( Karina Khmelnitskaya ),( Eugenii Shlyakhto ) 대한내과학회 2014 대한내과학회 추계학술발표논문집 Vol.2014 No.1

Background: Endothelial Progenitor Cells (EPCs) were fi rst described in 1997 and have since been the subject of numerous investigative studies exploring the potential of these cells in the process of cardiovascular damage and repair. Circulating EPCs are capable of differentiating into mature endothelial cells to assist in angiogenesis and vasculogenesis. Previous studies have suggested an inverse relationship between levels of circulating EPCs and the presence of coronary artery disease (CAD) or cardiovascular risk factors, whereas other studies have observed increased numbers of EPCs in the setting of acute ischemia. We investigated whether the number of EPCs in patients with chronic heart failure (CHF) was associated with severity CAD in patients undergoing coronary angiography, their correlations with the severity of stenosis, cytokines activation, growth factors, other clinic indicators. Methods: Peripheral blood EPCs assessed both as CD133+ cells and CD133+ cells coexpressing CD34 and vascular endothelial growth factor (VEGF) receptor-2 cells were studied in 82 men with ischemic heart disease and CHF I-IV class (NYHA), undergoing coronary angiography. Patients with acute coronary syndroms were excluded. Results: There was an decrease CD133+, CD34+/CD133+/VEGFR2+ cells in men with CHF and 3-vessel CAD, 4-vessel CAD compared 1-vessel CAD (P<0.05). Men with occlusion of coronary artery had lower CD133+, CD34+/CD133+/VEGFR2 cells (P<0.05). CD34+/CD133+/VEGFR2+ cells negative correlated to age, smoking, New York Heart Association class, left ventricular ejection fraction, number of myocardial infarctions, NT-proBNP, and positive - to VEGF, CD34+, CD133+ cells. Conclusions: In patients with CHF there were lower number of EPCs were associated with the presence of signifi cant angiographically CAD and number of vessels CAD, and EPC number correlated with maximum angiographic stenosis severity.

The Role of Garlic in Metabolic Diseases: A Review

Karina G. Perez-Rubio,Miriam Mendez-del Villar,Marisol Cortez-Navarrete 한국식품영양과학회 2022 Journal of medicinal food Vol.25 No.7

Garlic (Allium sativum L.) is a popular spice that has been widely used for thousands of years in traditional medicine. Several organosulfur compounds in garlic have been linked to its beneficial effects on health. Evidence from preclinical studies and clinical trials supports garlic's antihypertensive, antidiabetic, antiobesity, and hypolipidemic effects. This study aims to summarize clinical trial evidence regarding the effects of garlic on metabolic diseases and its mechanisms of action.

Japanese Perspective on Korean Reunification : An Analysis of Interrelations between Social Identity and Power

Karina Korostelina,Yuji Uesugi 이화여자대학교 국제통상협력연구소 2020 Asian International Studies Review Vol.21 No.1

The paper explores how experts in Japan assess and understand the process and consequences of the unification of the Republic of Korea (South Korea) and the Democratic People’s Republic of Korea (North Korea). Based on the theoretical framework of interrelations between social identity and power, this paper asks how Japanese experts frame the process of Korean unification and evaluate its impact on Japan. The data was collected in Tokyo, Japan, through 37 semi-structured and focus group interviews, then examining these interviews using phenomenological and critical discourse analysis. Analysis of data reveals the existence of four competing narratives rooted in the complex relations between meaning of identity, concepts of power, and Japanese policies toward the unification process. The paper expands the description of two narratives currently present in the existing literature, (1) threat and (2) peace, and introduces two new narratives, (3) democratic processes and (4) restorative justice. The final discussion explores how three groups of factors, (1) regional dynamics, (2) domestic policy, and (3) possible models of unification, influence the prevalence of a particular narrative as well as resulting policies of Japan toward Korean unification.

Livelihoods for women in Mindanao : A post-conflict reconstruction approach

Karina R. SANTILLAN 이화여자대학교 아시아여성학센터 2015 Asian Journal of Women's Studies(AJWS) Vol.21 No.1

Mahigit dalawang milyong tao ang nawalan ng tahanan at lumikas dahil sa kaguluhan sa Mindanao noong 2000 hanggang 2009. Sa panandaliang paghupa ng kaguluhan, sila ay bumalik sa kanilang komunidad upang simulan ang proseso ng muling pagtatag ng kanilang buhay. Ihinahayag ng artikulong ito kung ano ang naiambag ng mga babae sa proseso ng pagtatag matapos ang kaguluhan. Ito ay isang pag-aaral kung paano nakatulong ang mga babae sa pamamagitan ng paglahok sa mga gawaing pangkabuhayan. Tinitignan nito ang kinahinatnan ng limang proyektong pangkabuhayan na naisakatuparan sa indanao sa mga taong 2000 hanggang 2010. Sinukat ang saklaw ng ambag ng mga kababaihan sa proseso ng pagtatag sa pamamagitan ng pagtukoy ng mga benepisyong naibigay nila sa kanilang pamilya at komunidad, na siyang naging bunga ng kanilang paglahok sa mga gawaing pangkabuhayan. Pinatotohanan ng artikulong ito na ang paglahok ng mga babae sa iba’t ibang gawaing pangkabuhayan ay nakatulong sa proseso ng pagtatag sa aspetong ekonomiko, sosyal at politikal ng mga komunidad na apektado ng kaguluhan. Ikinikumpara din ng artikulong ito ang paglahok ng mga babae sa mga gawaing pangkabuhayan sa ibang mga paraan ng pagtatag na naisakatuparan ng mga gobiyerno at mga ahensya. Isinusulong nito ang paglaan ng mga gawaing pangkabuhayan na hinihimok ang paglahok ng mga babae bilang isang mahusay ng paraan para maisakatuparan ang proseso ng pagtatag matapos ang kaguluhan. The conflict inMindanao has displaced over two million people in the period 2000 to 2009. As it subsides, the displaced return to their communities and begin the process of reconstruction. This paper studies how women contributed to the post-conflict reconstruction of Mindanao by engaging in livelihood activities. It explores five different livelihood intervention projects implemented in Mindanao between 2000 and 2010. The extent of women’s contribution to post-conflict reconstruction is measured by identifying the benefits gained at household and community levels, generated by women’s livelihood work. I argue that women’s participation in such activities have led to economic, social and political reconstruction of the communities affected by in Mindanao. This paper also compares the women’s livelihoods approach with other reconstruction strategies. It also illustrates that interventions for reconstruction therefore must include livelihood programs that encourage women’s participation, as exemplified by the experience of Mindanao.

Biochemical profile in an infant with neonatal hemochromatosis shows evidence of impairment of mitochondrial long-chain fatty acid oxidation

Karina Lucio de Medeiros Bastos,Caio Robledo Quaio,Fabiana Roberto Lima,Iana Manuelle Araújo,Candice Alves Tavares Araújo,Flávia Balbo Piazzon,Ismael Dale Cotrim Guerreiro da Silva,Gabriel Nuncio Bene 대한간학회 2019 Clinical and Molecular Hepatology(대한간학회지) Vol.25 No.1

Improving the Viability of Freeze-dried Probiotics Using a Lysine-based Rehydration Mixture

( Karina Arellano ),( Haryung Park ),( Bobae Kim ),( Subin Yeo ),( Hyunjoo Jo ),( Jin-hak Kim ),( Yosep Ji ),( Wilhelm H. Holzapfel ) 한국미생물생명공학회(구 한국산업미생물학회) 2021 한국미생물·생명공학회지 Vol.49 No.2

The probiotic market is constantly continuing to grow, concomitantly with a widening in the range and diversity of probiotic products. Probiotics are defined as live microorganisms that provide a benefit to the host when consumed at a proper dose; the viability of a probiotic is therefore of crucial importance for its efficacy. Many products undergo lyophilization for maintaining their shelf-life. Unfortunately, this procedure may damage the integrity of the cells due to stress conditions during both the freezing and (vacuum-) drying process, thereby impacting their functionality. We propose a lysine-based mixture for rehydration of freeze-dried probiotics for improving their viability during in vitro simulated gastric and duodenum stress conditions. Measurement of the zeta potential served as an indicator of cell integrity and efficacy of this mixture, while functionality was estimated by adhesion to a human enterocyte-like Caco-2 cell-line. The freeze-dried bacteria exhibited a significantly different zeta potential compared to fresh cultures; however, this condition could be restored by rehydration with the lysine mixture. Recovery of the surface charge was found to influence adhesion ability to the Caco-2 cell-line. The optimum lysine concentration of the formulation, designated “Zeta-bio”, was found to be 0.03 M for improving the viability of Lactiplantibacillus plantarum Lp-115 by up to 13.86% and a 7-strain mixture (400B) to 41.99% compared to the control rehydrated with distilled water. In addition, the lysine Zeta-bio formulation notably increased the adherence ability of lyophilized Lp-115 to the Caco-2 cell-line after subjected to the in vitro stress conditions of the simulated gastrointestinal tract passage.

Identity and power in Ukraine

Karina V.Korostelina 한양대학교 아태지역연구센터 2013 Journal of Eurasian Studies Vol.4 No.1

This paper analyzes the coercive and legitimate forms of power in Ukraine. It describes the crisis of legitimacy in Ukraine as a contradiction between a blatantly cruel system of capitalism dominated by a few oligarchs, and the lingering remnants of a Soviet mentality. Two strategies are used by the Government to stoke the crisis. First, increased identification with ethnic or regional groups are instrumentally used by the Government to take attention from economic and class issues. Second, the incorporation of a Soviet meaning of power into the new national identity and presentation of it as core norms, believes, and values of the people of Ukraine competes with alternative Ukrainian identity concepts. The paper analyzes five main features of the Soviet meanings of power – political, social, and economic paternalism, perception of power as source of profit and violence, and the dual reality of power with the gap between official narratives of power and a real life. The process of incorporation of the Soviet concept of power into national identity is facilitated by the process of national identity formation that helped to preserve the Soviet perception of power, because of the absence of a new ideology, a lack of critical assessment of the Soviet past, an absence of the vision of outcome, an embryonic culture of democracy, and contributions of all the presidents to the preservation of the Soviet meaning of power. People justify the system as legitimate and fair for many reasons: out of historic habit and deemed moral obligations, self-interests and/or a fear of sanctions, identification with the ruler, zones of indifference, an absence of will and self-confidence, desire to support a strong leader based on ambiguity intolerance, hierarchy – enhancing ideologies, and a general tolerance of injustice. The obedience of subjects is connected with the strength of will of the subjects and the social structures of the society. In Ukraine, the society is not united, not organized, has no identity of “us”, no civic accountability, nor even any real interest in such matters. Civil society levels are very low, as reflected by limited opportunities for civic responsibility and participation and few demands from the society.

Plants cultivated in Choco, Colombia, as source of repellents against Tribolium castaneum (Herbst)

Karina Caballero-Gallardo,Nayive Pino-Benitez,Nerlis Pajaro-Castro,Elena Stashenko,Jesus Olivero-Verbel 한국응용곤충학회 2014 Journal of Asia-Pacific Entomology Vol.17 No.4

Essential oils (EOs) of eight plants collected in Choco, Colombia, including Piper divaricatum, P. pseudolanceifolium,P. confertinodum, P. diazanum, Ocimum campechianum, Siparuna conica, Mikania micrantha and Hedychiumcoronarium, were analyzed by gas chromatography–mass spectrometry and tested as repellents against Triboliumcastaneum, using the area preference method, after 2 and 4 h exposure. The main components found in EOswere methyl eugenol, trans-β-cariophyllene, methyl eugenol, α-pinene, δ-cadinene, γ-elemene, α-pinene and1,8-cineol, for O. campechianum, P. pseudolanceifolium, P. divaricatum, P. confertinodum, P. diazanum, S. conica,M. micrantha, and H. coronarium, respectively. Best repellent activities were observed for oils fromO. campechianum and P. pseudolanceifolium with mean repellent concentration (RC50) values of 0.00006 and0.0001 μL/cm2 after 2 h, and 0.00003 and 0.0001 μL/cm2 after 4 h, respectively; whereas the least potent wasthat from M. micrantha, with RC50 values of 0.074 and 0.040 μL/cm2 at 2 and 4 h exposure times, respectively. Based on average percentage repellence, oils from P. pseudolanceifolium and O. campechianum were classifiedas Class IV repellents and were better than the commercial repellent IR3535, classified as Class II. These data evidencethe Choco region as an important source of natural repellents with promising commercial opportunities.