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Sang Won Min,Seog Ju Kim,Don Hur 대한전기학회 2013 Journal of Electrical Engineering & Technology Vol.8 No.2
In this paper, a novel approach for optimized installation and operations of battery energy storage system (BESS) and electric double layer capacitor (EDLC) modules for the renewable energy based intermittent generation is presented for them to be connected with an electric power grid. In order to make use of not merely the high energy density of battery but also the high power density of EDLC modules, it is very useful to devise the hybrid system which combines BESS and EDLC modules. The proposed method adopts the linear programming to calculate the optimized capacity as well as the quadratic programming to transmit the optimal operational signals to BESS and EDLC modules. The efficiency of this methodology will be demonstrated in the experimental study with the real data of wind speed in Texas.
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Molecular Function of the Gene Encoding RING-H2 Finger Protein and Its Interacting Partners
Sung Don Lim,Ju Kyong Lee,Cheol Seong Jang 한국작물학회 2010 한국작물학회 학술발표대회 논문집 Vol.2010 No.04
All aspects of plant life are controlled by the regulated synthesis of new proteins and the precise degradation of preexisting proteins, predicting up to 50% of total plants protein is replaced every week. The ubiquitin/26S proteosome pathway is known to be one of mechanisms to regulate signal pathways, developmental process and abiotic/biotic stress responses via protein degradations. In the previous study, we have identified a large number of the RING ubiquitin ligase proteins whose functions have been clarified in the protein degradation pathway. Curiously, one RING-H2 finger protein gene evidenced striking differences in expression patterns in response to salt and dehydration stress between leaf and culm-node tissues. Characterization of the gene evidenced its function as E3 ubiquitin ligase activity by using an in vitro ubiquitination assay. We have constructed a library with rice culm-node tissues under salt stress for Yeast two hybrid assay and performed primary yeast two-hybrid screening with the gene as a bait. A total of 13 candidate genes were isolated as positive interacting partners. Gene ontology of most candidate genes appears to be related with various abiotic stresses. Therefore, the RING-H2 finger protein genes might function to regulate plant abiotic stress responses via protein degradation pathways.
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( Sang Gyune Kim ),( Jeong-ju Yoo ),( Young Seok Kim ),( Bora Lee ),( Soung Won Jeong ),( Jae Young Jang ),( Sae Hwan Lee ),( Hong Soo Kim ),( Young Don Kim ),( Gab Jin Cheon ),( Boo Sung Kim ) 대한간학회 2016 춘·추계 학술대회 (KASL) Vol.2016 No.1
Aims: Non-selective beta-blocker (NSBB) use has been established in the primary and secondary prevention of esophageal variceal hemorrhage. However, the use of beta-blockers in cirrhotic patients with ascites is still under debate. In this study, we compared overall survival (OS) in cirrhotic patients with ascites (≥grade 2) and esophageal varices according to their treatment strategies between endoscopic band ligation (EBL) and NSBB. Methods: This retrospective study included consecutive 269 patients who were diagnosed as liver cirrhosis complicated with esophageal varices and ascites (≥grade 2) in a tertiary single center in Korea. Patients were divided into 3 groups which were EBL only, NSBB, non-treatment group. A Cox-proportional hazard analysis was performed to compare overall survival between the groups. Results: The mean age was 53.8±10.9 years, and median follow-up duration was 37.7 months (IQR, 12.4-65.2). Overall survival was significantly shorter in the NSBB group followed by non-treatment group and EBL only group (median, 47.5 vs. 61.1 vs. 77.0 months; P=0.003). A multivariate analysis showed that the use of NSBB were an independent poor prognostic factor for shorter overall survival (adjusted hazard ratio, 1.98; 95% confidence interval, 1.31-2.98; P<0.001) after adjusted by Child-Pugh class. Conclusions: The use of NSBB worsens the prognosis of cirrhotic patients patients with significant ascites. These results suggest that EBL is a more appropriate treatment option of esophageal varices when complicated with ascites (≥grade 2).
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The production of LiCoO2 cathode thick films for an all-solid-state microbattery
Sung-Man Lee,Seung-Tae Lee,Hyeon-Ju Kim,Seung-Don Choi 한양대학교 세라믹연구소 2007 Journal of Ceramic Processing Research Vol.8 No.2
Crack-free LiCoO2 films with a thickness more than 10 μm have been prepared by a sol-gel derived screen-printing process, using two different-sized LiCoO2 powders (mean particle sizes: 6 μm and 0.8 μm). The slurry as a coating medium consists of LiCoO2 powders and a LiCoO2 sol-gel precursor solution, which gives a well-dispersed slurry with high powder content. The slurry is screen-printed onto a Pt-coated alumina and annealed at relatively low temperatures as in a conventional solgel process. The feasibility of applying the fabricated films as cathodes for lithium rechargeable batteries is demonstrated. No obvious cracking after cycling was observed. Excellent cyclability was obtained. The films prepared using fine grain powders are less porous than those made from large grain powders, which lead to a better Coulombic efficiency for electrodes using the former. It is suggested that the novel process is promising for fabricating LiCoO2 thick films for potential applications in all-solid-state rechargeable lithium batteries. Crack-free LiCoO2 films with a thickness more than 10 μm have been prepared by a sol-gel derived screen-printing process, using two different-sized LiCoO2 powders (mean particle sizes: 6 μm and 0.8 μm). The slurry as a coating medium consists of LiCoO2 powders and a LiCoO2 sol-gel precursor solution, which gives a well-dispersed slurry with high powder content. The slurry is screen-printed onto a Pt-coated alumina and annealed at relatively low temperatures as in a conventional solgel process. The feasibility of applying the fabricated films as cathodes for lithium rechargeable batteries is demonstrated. No obvious cracking after cycling was observed. Excellent cyclability was obtained. The films prepared using fine grain powders are less porous than those made from large grain powders, which lead to a better Coulombic efficiency for electrodes using the former. It is suggested that the novel process is promising for fabricating LiCoO2 thick films for potential applications in all-solid-state rechargeable lithium batteries.
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Ju, Kyung Don,Shin, Eun Kyoung,Cho, Eun Jin,Yoon, Hyun Bae,Kim, Hyo Sang,Kim, Hwajung,Yang, Jaeseok,Hwang, Young-Hwan,Ahn, Curie,Oh, Kook-Hwan American Physiological Society 2012 American journal of physiology. Renal physiology Vol.302 No.5
<P>Pyruvate is an endogenous antioxidant and anti-inflammatory substance. The present study was implemented to investigate the protective effect of ethyl pyruvate (EP) against the development and progression of diabetic nephropathy in an in vivo and in vitro model. Diabetic rats were prepared by injecting streptozotocin (65 mg/kg). Those that developed diabetes after 72 h were treated with EP (40 mg/kg) intraperitoneally. Diabetic rats without pyruvate treatment and nondiabetic rats were used for control. As an in vitro experiment, rat mesangial cells cultured primarily from Sprague-Dawley rats were treated in high-glucose (HG; 50 mM) or normal-glucose (NG; 5 mM) conditions and with or without pyruvate. Pyruvate-treated diabetic rats exhibited decreased albuminuria and attenuated NADPH-dependent reactive oxygen species generation. Immunohistochemistry showed reduced laminin, type IV collagen, and fibronectin deposition in the glomeruli compared with nontreated diabetic rats. Parallel changes were shown in tissue mRNA and protein expression levels of monocyte chemoattractant protein-1, transforming growth factor-β1, laminin, fibronectin, and type IV collagen in the kidney. Concordantly, protective effects were also exhibited in the mesangial cell culture system. These findings suggest that pyruvate protects against kidney injury via NADPH oxidase inhibition. The present study established that activation of NADPH oxidase plays a crucial role in diabetes-induced oxidative stress, glomerular hypertrophy, and ECM molecule expression. Pyruvate exhibited a renoprotective effect in the progression of experimental diabetic nephropathy. Future research is warranted to investigate the protective mechanism of pyruvate more specifically in relation to NADPH oxidase in diabetic nephropathy.</P>
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