영월지역 생태·문화관광 활성화 방안에 관한 연구

정병웅,전영철 도립 강원전문대학 1999 道立 江原專門大學 論文集 Vol.2 No.-

The tourism development in Yongwol area has put its emphasis on the economic efficiency up to current dates, which, however, has not reimburses the consequential profit to the local citizens. Furthermore, the natural environment, cultural preservation and awareness in that region which the tourism development, gives rise to have, in a greats extent, been overlooked, whereas, rather negative aspects such as nature destruction, environmental pollution, local indigenous, etc, only emerged as the consequential results, which induced the expansion of regional egotism for tourism development. As we see in many instances, both, in and out of the country, thin type of development typically reflects on ignorance of the regional characteristics of autonomies by the central government and conglomerates.

신경인성 방광 1례에 대한 임상고찰

김만호,이지영,이정원,조충식,김철중 대전대학교 한방병원 2002 惠和醫學 Vol.11 No.1

From January 10th 2002 to February 17th 2002, the clinical study was carried out I case of patient in trouble with voiding difficulty such as urinary incontinence, enuresis and urinary frequency after the L₄-L_(5) HN P operation, who had been hospitalised in the Dept. of Internal Medicin e, Cheon-An Oriental Medical Hospital, Daejeon University. The results were as following 1. For this case, we could get the better result using Bo-Joong-lk-Gi-Tang(補中益氣湯) in the treating period. 2. We could get the effective result that the case of voiding difficulty after HNP operation and cerebral infarction by conservative therapy of oriental medicine such as acupuncture, moxibustion and herb medicine.

아동의 하악골에 발생한 복합 치아종의 외과적 처치에 관한 증례보고

이긍호,최영철,정우성 大韓小兒齒科學會 1999 大韓小兒齒科學會誌 Vol.26 No.3

악골에서 비교적 흔한 빈도로 발생하는 치아종은 치배조직의 과성장으로 인하여 발생한다.세계보건기구에서는 치아종을 복잡 치아종과 복합 치아종으로 구분하고 있다.치아종은 악골내 모든 부위에서 발생할 수 있지만 치아와 유사한 복합 치아종은 비교적 상악 전치부에 호발하고,불규칙한 형태를 나타내는 복잡 치아종은 하악 구치부에 호발한다.치아종의 원인은 정확히 알려져 있지 않으며 치배에 대한 구소적인 외상이나 감염이 주된 요인으로 추측되고 있고,최근에는 유전적인 원인에 대해서도 연구되고 있으나 아직 확실히 입증되지는 않고 있다.일반적인 증상이 없기 때문에 일상적인 방사선 검사에서 주로 발견되고 영구치의 맹출지연이나 유치의 만기잔존 등이 증상이 있을 수 있다.치아종은 구강내의 어떤 부위에서도 발생이 가능하고 드물기는 하지만 상악동,하악의 하연,하악지 및 하악과두 하방에서 발견되기도 하며,이공 부위에서 발생되는 경우도 있다. 치아종은 발육중인 치열과 악궁에 미치는 영향을 최소화하기 위하여 발견되는 즉시 낭포 및 주위 연조직을 함께 외과적으로 제거하는 것이 바람직하다.환자의 연령과 치과치료에 대한 협조도,영구치열의 발육상태,치아종의 악골내 위치 및 동시적인 치과치료가 요구되는 가를 고려하여 외래 진료실에서 하는 경우도 있고 전신마취를 통하여 하는 경우도 있다. 본 증례는 치아종의 악골내 위치가 깊지 않고 치과치료에 대한 협조도가 양호하다고 판단되는 환아에서는 외래 진료실에서 국소마취하에 수술하여 치료하였고,연령이 어리고 치아종이 악골내 위치가 깊어 장시간의 시술 시간이 요구되고 동시에 보존적인 치과치료가 필요한 환아에서는 전신마취하에 치료한 것을 보고한 것이다.두 증례에서 수술 4개월 후 외과적 결손 부위에 골이 형성되었고,매복된 영구치의 맹출이 정상적으로 이루어진 것으로 나타났다. The Odontogenic is relatively a common benign odontogenic tumor and caused by overgrowth of odontogenic tissues.The recent classification by World Health Organization divides odontoma into 2 groups such as compound odontoma and complex odontoma.Compound odontoma comprises dental tissues,resembling the morphology of a tooth and has predilection for the anterior maxilla.In contrast,complex odontoma has unorganized mass,not resembling the normal tooth and has predilection for the posterior mandible.The etiology of odontoma is unknown and almost asymptomatic.So,it usually is found in routine radiographic examination,and most common presenting symptom is impacted or unerupted permanent teeth and ratained primary teeth.It can occurs almost anywhere in jaws. It is desirable that odontoma should be removed by surgical enucleation including follicle and surrounding soft tissues.Considering the age and behavioral cooperation of patient,the develoment of parmanent dentition,the location of odontoma in jaw,the need for the concomitant operative dentistry,operation is performed in outpatient department with/without sedation or under general anesthesia with endotracheal intubation. In this case report,2 patients with compound odontoma were treated by surgical enucleation including follicle and surrounding soft tissues.One patient,about 5years old,was treated under general anesthesia and concomitant operative density was performed.The other patient,about 11years old,was treated under local anesthesia in outpatient department.In 2 cases,after 4 months,surgical defects were filled with new bone and normalization of eruption path of impacted permanent teeth was observed.

정신분열병 환자들의 自己灣入에 관한 예비 연구

박성봉,김영미,전성일,이기철,김영훈,정영조,이영렬,이정호,최영민 大韓神經精神醫學會 1997 신경정신의학 Vol.36 No.6

목 적 : 정 신분열병 환자의 자기만입 정도에 영향을 미치는 인구학적 변인들 및 질병연관 변인들을 규명해 보고자 하였다. 또한. 환자들의 자기만입과 병식 사이의 연관성. 자기만입과 자존심 사이의 연관성을 알아보고자 하였다. 방 법 : 정신과 의사가 병록지와 면담을 통하여 대상 정신분열병 환자들의 인구학적 변인들 및 질병연관 변인들에 관한 자료를 얻고 환자들의 병식 정도를 평가한 후, 환자들로 하여금 자기보고형의 자기만입 척도와 자존심 척도를 시행하게 하였다. 총 111명의 환자가 연구대상으로 선택되었다. 결과: . 1) 여자가 남자보다 유의하게 높은 자기만입 척도 점수를 나타내었다 2) 질병연관 변인들 중 하위집단 사이에 자기만입 척도 점수의 유의한 차이를 보이는 변은 없었다. 3) 자기만입 척도 점수와 병식 점수 사이에 유의한 상관관계가 없었다. 4) 자기만입 척도 점수와 자존심 척도 점수 사이에 유의한 역상관 관계를 보였다. 결 론 : 본 예비 연구의 결과로 보아 정신분열 병 환자의 병식이 부족한 상태에서도 자기만입이 진행될 수 있으며. 자기만입이 심할수록 환자의 자존심이 저하되는 것으로 생각된다. 또한 여자 환자들이 남자 환자들보다 자기만입에 더 취약한 것으로 생각된다. 따라서 정신분열 병 환자의 이해와 치료를 위하여 자기만입에 관한 지속적인 연구가 필요할 것으로 생각된다. objective : This study was conducted to identify demographic variables and illness related variables which may affect the severity of self-engulfment in the patients with schizophrenia. We also studied the relationship between self-engulfment and insight, and the relationship between self-engulfment and self-esteem. Methods : Data on demographic variables and illness related variables for the subjects were gathered from hospital records and clinical interviews by the psychiatrists. Degree of insight for the subjects was assessed through clinical interviews by the psychiatrists. Degree of self-engulfment and self-esteem for the subjects was assessed from the self-engulfment scale and the self-esteem scale respectively. A total of 111 patients with schizophrenia were selected for statistical analysis. Results 1) The females exhibited significantly higher scores than the males on the self-engulfment scale. 2) There was no illness related variable, which exhibited a significant difference among subgroups on the self-engulfment scale. 3) There was no significant correlation between the self-engulfment scores and the insight 4) There was a significantly inverse correlation between the self-engulfment scores and the self-esteem scores. Conclusion : The results of this preliminary study suggest that self-engulfment may develop despite lack of insight and that there was inverse relationship between self-engulfment and self-esteem in the patients with schizophrenia. It also suggests that females are more subject to self-engulfment than males. So, authors suggest that it is valuable to do further studies of self-engulfment in the patients with schizophrenia.

Report of tree Burspahelenchus (Nematoda: Parasitaphelenchidae) species distributed in Korea

Hyerim Han,Bo-Young Han,Yeong-Jin Chung,Sang-Chul Shin 한국응용곤충학회 2008 한국응용곤충학회 학술대회논문집 Vol.2008 No.10

Pine wood nematode(PWN), Bursaphelenchus xylophilus, is a causal organism to induce pine wilt disease in many varieties of pine trees. PWN is mainly distributed in the East Asia including Japan, China, and Korea, but it was originally imported from the North America of the West. Over 70 species of Bursaphelenchus have been reported, but they are morphologically similar to each other. In Korea, only two species of Bursaphelenchus xylophilus, B. mucronatus (both Asian type and European type) have been reported however, a recent survey showed the distribution of extra species of Bursaphelenchus in dead trees. Three isolates, BSPD-1, BSPD-2, and BSPL-1, were identified as Bursaphelenchus thilandae, B. hylobianum, and B. doui, respectively, which was determined by both morphological and molecular biological characteristics. Both BSPD-1 and BSPD-2 were originally collected from Pinus densiflora in Namyangju and BSPL-1 came from Liriodendron tulipifera in Wanju. The morphology of each species were compared from the original descriptions focusing on male spicule and female tail and reproductive organ. A molecular diagnosis method, ITS-RFLP was applied to confirm morphological identification. Genomic DNA was extracted from a single individual nematode and ITS DNA was amplified by PCR. Amplified ITS was digested by 5 different restriction enzymes (Rsa I, Hae III, Msp I, Hinf I, and Alu I) and provided a discriminatory profile for different species of Bursaphelenchus. The three species, B. thilandae, B. hylobianum, and B. doui, are all unrecorded species in Korea.

Genotoxicity Study of Polysaccharide Fraction from Astragalus membranaceus's Aerial Parts

Yeong-Chul Park,Min Hee Kim,Jung Woo Kim,Jong-Bong Kim,Jae Geun Lee,Chang Yeon Yu,Seung-Hyun Kim,Ill Min Chung,Jae Kwang Kim,Ri Na Choi,Jung Dae Lim 한국독성학회 2014 Toxicological Research Vol.30 No.2

Radix Astragali, the root of Astragalus (A.) membranaceus, has been applied in a variety of diseases for a long time in Asian countries such as Korea and China. In addition, the aerial parts such as leaves and stems of A. membranaceus have received a great deal of attention. Recently, the polysaccharide fraction showing a potent immunomoduating activity was isolated from the aerial parts of A. membranaceus. Thus, the aerial parts of A. membranaceus would be worthy enough for a food material and a dietary supplement. However, they should be safe even though valuable. In our previous study, it was estimated that NOAEL for female rats are 5000 mg/kg/day of the crude polysaccharide fraction from A. membranaceusaboveground parts. As a series of safety evaluation, genotoxicity test for the crude polysaccharide fraction was carried out in this study. In conclusion, the three genotoxicity assays provided strong overall support that the crude polysaccharide fraction lacks mutagenic and/or clastogenic potential under the GLP-based test conditions. This indicates the aerial parts of A. membranaceus would be safe enough for a food material and a dietary supplement.

Higher infiltration by Th17 cells compared with regulatory T cells is associated with severe acute T-cell-mediated graft rejection

Chung, Byung-Ha,Oh, Hye-Jwa,Piao, Shang Guo,Sun, In-O,Kang, Seok-Hui,Choi, Sun-Ryoung,Park, Hoon-Suk,Choi, Bum-Soon,Choi, Yeong-Jin,Park, Cheol-Whee,Kim, Yong-Soo,Cho, Mi-La,Yang, Chul-Woo Korean Society for Biochemistry and Molecular Bion 2011 Experimental and molecular medicine Vol.43 No.11

The aim of this study was to evaluate whether the Th17 and Treg cell infiltration into allograft tissue is associated with the severity of allograft dysfunction and tissue injury in acute T cell-mediated rejection (ATCMR). Seventy-one allograft tissues with biopsy-proven ATCMR were included. The biopsy specimens were immunostained for FOXP3 and IL-17. The allograft function was assessed at biopsy by measuring serum creatinine (Scr) concentration, and by applying the modified diet in renal disease (MDRD) formula, which provides the estimated glomerular filtration rate (eGFR). The severity of allograft tissue injury was assessed by calculating tissue injury scores using the Banff classification. The average numbers of infiltrating Treg and Th17 cells were $11.6{\pm}12.2cells/mm^2$ and $5.6{\pm}8.0cells/mm^2$, respectively. The average Treg/Th17 ratio was $5.6{\pm}8.2$. The Treg/Th17 ratio was significantly associated with allograft function (Scr and MDRD eGFR) and with the severity of interstitial injury and tubular injury ($P$ < 0.05, all parameters). In separate analyses of the number of infiltrating Treg and Th17 cells, Th17 cell infiltration was significantly associated with allograft function and the severity of tissue injury. By contrast, Treg cell infiltration was not significantly associated with allograft dysfunction or the severity of tissue injury. The results of this study show that higher infiltration of Th17 cell compared with Treg cell is significantly associated with the severity of allograft dysfunction and tissue injury.

S-23 PGA sheet application to prevent esophageal stricture after ESD for recurrent esophageal cancer

( Yeong Jin Kim ),( Jun Chul Park ),( Hyunsoo Chung ),( Sung Kwan Shin ),( Sang Kil Lee ),( Young Chan Lee ) 대한내과학회 2016 대한내과학회 추계학술대회 Vol.2016 No.1

A 73-year-old man was diagnosed with esophageal cancer (cT1N1M0, stage IIb). He received CCRT, included 4 cycles of monthly fluorouracil, cisplatin, and radiation (54 Gray). At 96 months after CCRT, he had multiple Lugol-unstained lesions 22-32 cm from the UI. The pathological results indicated well-differentiated squamous cell carcinoma at 22 cm and 25 cm from the UI, and squamous epithelial dysplasias at 25-32 cm from the UI. We performed ESD (22 - 32 cm from the UI, represented over 90% of the esophageal circumference), successful en-bloc resection was achieved without adverse events. On the day after ESD, a 100×50 mm PGA sheet was placed with hemoclips, followed by application of a fibrin glue. Follow-up endoscopy was performed 7 weeks after ESD, there was a focal stricture at 26 cm from the UI. The endoscope could not pass through the narrow lumen. We performed through-the-scope balloon dilatation. Thereafter, the endoscope could pass through the narrow lumen. The patient has not experienced any recurrent symptoms over 1 year, and the most recent endoscopy showed the absence of a stricture. Esophageal stenosis frequently occurs in patients with defects involving over three-fourths of the circumference of the esophagus after ESD. And, patients usually require multiple endoscopic sessions for the management of a stricture, especially when present in a long segment. Iizuka et al. reported that the use of PGA sheets is safe and effective for reducing the incidence of esophageal stricture development after ESD. Our patient had a long segment length and previous CCRT treatment history which resulted in severe fibrotic lesions associated with a high risk of esophageal stricture development and perforation after balloon dilatation. Although an esophageal stricture was noted 7 weeks after ESD, the focal stricture was only 1-2 cm in the lesion of 10 cm. Moreover, only 1 balloon dilatation procedure was sufficient for relieving dysphagia. In conclusion, the use of a PGA sheet appears to be a promising method for preventing long stricture development and reducing the number of endoscopic dilatations required, especially after ESD for recurrent esophageal cancer previously treated with CCRT.

Preliminary Surgical Result of Cervical Spine Reconstruction with a Dynamic Plate and Titanium Mesh Cage

Chung, Dae-Yeong,Cho, Dae-Chul,Lee, Sun-Ho,Sung, Joo-Kyung The Korean Neurosurgical Society 2007 Journal of Korean neurosurgical society Vol.41 No.2

Objective : The objective of this study was to validate the effects of a titanium mesh cage and dynamic plating in anterior cervical stabilization after corpectomy. Methods : A retrospective study was performed on 31 consecutive patients, who underwent anterior cervical reconstruction with a titanium mesh cage and dynamic plating, from March 2004 to February 2006. Twenty-four patients had 1-level and 7 had 2-level corpectomies. Ten patients underwent surgery with a cage of 10-mm diameter and 21 with 13-mm diameter. Neurological status and outcomes were assessed according to Odom's criteria. Sagittal angle, coronal angle, settling ratio, sagittal displacement, and cervical lordosis were used to evaluate the radiological outcomes. Results : In overall, 26 [83.9%] of 31 showed excellent or good outcomes. Thirteen percent [4 cases] of the patients developed surgical complications, such as hoarseness, transient dysphagia, or nerve root palsy. Seven [22.6%] patients had reconstruction failure:5 [20.8%] in the 1-level corpectomy group and 2 [28.5%] in the 2-level corpectomy group. Revisions were required in 2 patients with plate pullout due to significant instability. However, none of 5 patients who demonstrated cage displacement or screw pullout, underwent a revision. Radiographs revealed bony consolidation in 96.3% of the patients, including 6 patients with implantation failure during the follow-up period. Conclusion : Based on our preliminary results, the titanium mesh cage and dynamic plating was effective for cervical reconstruction after corpectomy. The anterior cervical reconstruction performed with dynamic plates is considered to reduce stress shielding and greater graft compression that is afforded by the unique plate design.

A Study on the Ventilation Method for a Factory with a Sealed Structure

Yeong-Sik Kim,Chung-Seob Yi,Dae-Chul Lee,Hyo-Min Jeong,Han-Shik Chung 한국동력기계공학회 2014 동력시스템공학회지 Vol.18 No.6