하악골 절제술후 재이식된 돌결자가골 재이식 : 치험 3례

김 식,김수관,김운규,김수민,류종희,이준길,조경안,김수흥,정태영,여환호 대한악안면성형재건외과학회 2001 Maxillofacial Plastic Reconstructive Surgery Vol.23 No.2

We described three cases of immediate reimplantation of a frozen-thawed autogenous mandible composed of a mixture of iliac bone, marrow, and particulate hydroxyapatite in tumors of the mandible. Acceptable outcomes were obtained in three patients who underwent immediate autogenous mandibular graft reconstruction. The conditions leading to successful outcome of the procedure are also discussed. Reimplantation of frozen autogenous lesioned mandible was performed in three patients with mandibular tumors. Two reimplanted grafts survived without complications following surgery. One case had postoperative infection that resolved with appropriate antibiotic treatment. There were no recurrences of the primary lesions. Satisfactory facial contour after surgery was achieved. These results are most promising, and we believe that, with further refinement, this technique will offer a new and acceptable modality for facial reconstruction in patients with cancer.

전치부 반대교합아동의 발음장애에 관한 음향적 연구

박정삼,손동수,이상훈,김진태,한세현,장기택,김종철 大韓小兒齒科學會 1996 大韓小兒齒科學會誌 Vol.23 No.2

It has widely known for speech problem in patients with malocclusion,but there have been insufficient studies on degrees of serverity.Patients with openbite and CIⅢ malocclusion usually have speech problem.It has widly known that fricative /s/ is pronunciated most abnomally in CIⅢ malocclusion than any other consonant.Therefore 20 childen with anterior crossbite selected for control group.7 sounds such as /사(sa),서(sδ),소(so),수(su),스(sω),시(si),세(se)/ were recorded,and the formants and formants ratio were measured by using Sensimetric Speech Station,which is speech analyzing program in IBM pc. The results were as follows: 1.In anterior crossbite group,F1 of all 7 sounds were significantly higher than normal anterior relationship group(P<0.05). 2.There were no significant difference in F2 between two groups except/소(so),수(su)/(P>0.05). 3.In anterior crossbite group,F2/F1 ratio of all 7 sounds were significantly smaller than normal anterior relationship group(P<0.05). 4.There were no significant difference in accordance with tongue position(P>0.05).

동적 트래픽 부하를 갖는 분산 네트워크 시스템의 최적 재구성에 관한 연구

김명희,주수종,김현주 圓光大學校 1996 論文集 Vol.31 No.2

네트워크 기술의 발달과 시스템의 가격 하락으로 최근에는 단일 메인프레임의 사용보다는 네트워크 시스템의 사용에 더 많은 관심을 갖게 되었다. 분산 네트워크 시스템의 성능은 네트워크의 상호연결 형태와 시스템들간에 부여되는 트래픽(부하) 형태에 크게 의존한다. 따라서 시스템 성능(평균 패킷 전달 시간)을 개선시키기 위해 재구성 알고리즘을 사용하여, 현 동적 트래픽 형태에 가장 적합한 네트워크 구조를 갖는 분산 네트워크 시스템으로 최적 재구성하고자 한다. 시스템의 최적 구성 상태를 찾는 과정은 이산 최적화 예측 문제(Discrete Optimization with Estimation(DOE) problem)이다. 이분제를 해결하기 위해서 전형적인 알고리즘의 하나인 Simulated Annealing(SA) 알고리즘보다는 더 효과적인 Stochastic Ruler(SR)알고리즘을 제시한다. 끝으로 Stochastic 환경에서 분산 네트워크 시스템의 한 예를 통해 최소의 평균 패킷 전달 시간을 갖는 최적 구성 상태를 추적하는 과정을 보이고, 제의한 재구성 알고리즘이 부정확한 추정값을 얻을 한계 조건을 밝힌다. As the number of network technology increases and systems become cheaper, many researchers are more interested in networks rather than mainframes. The performance of such a network depends on how to interconnect and how to give traffic patterns. Hence, we are to reconfigure a network using reconfiguration algorithm to improve the network performance (mean packet delay) by dynamically altering their structure to better fit the current dynamic traffic. To find the optimal configuration of a network is a difficult discrete optimization with estimation(DOE) problem. We make use of more efficient a reconfiguration algorithm (the Stochastic Ruler Algorithm) than a simulated annealing, one of the traditional approaches. As a result, we show the procedures for tracing the optimal configuration with minimum mean packet delay of the network considered in the stochastic environment, and get a condition of when the estimate gets so bad that the reconfiguration algorithm no longer functions well.

국내에서 분리된 Vancomycin 내성 장구균에 대한 분자역학적 연구

김수정,이남용,배직현,이경원,이위교,김의종,최명식,백경란,김성민,송재훈 대한감염학회 1998 감염 Vol.30 No.1

목 적 : 장구균은 병원 감염의 원인균으로서 최근 그 빈도와 중요성이 증가하고 있다. 특히 vancomycin에 내성을 보이는 장구균(VRE)은 효과적인 치료약제가 드물고, 그 내성 유전자가 vancomycin에 감수성을 보이는 다른 장구균이나 그람양성 구균에 전달될 수 있어 임상적인 중요도가 더욱 크다. 본 연구에서는 국내 5개 병원에서 분리된 VRE 균주의 표현형과 유전형을 결정하고, 분자역학적 방법을 이용하여 유전적 연관성 여부를 밝히고자 하였다. 방 법 : 각 병원에서 수집된 균주는 환자의 임상 검체에서 또는 VRE 집락화에 대한 선별검사에서 분리된 균주였다. 이들을 대상으로 vancomycin과 teicoplanin의 MIC를 측정하여 표현형을 결정하였으며, PCR로 vancomycin 내성 유전자를 증폭하여 유전형을 결정하였다. 또한 이들중 vanA와 vanB 유전자를 갖는 균주들을 대상으로 플라스미드 분석과 PFGE를 시행하였다. 결 과 : VRE로 최종 동정된 균주들은 42균주(E. faecium 21주, E. faecalis 6주, E. avium 2주, E. casseliflavus 13주)였으며, 항균제 감수성 양상으로 결정한 표현형은 VanA, VanB, VanC형이 각각 14주(33%), 7주(17%), 21주(50%)였다. PCR로 결정한 유전형은 vanA 12주(E. faecium), vanC 16주 였으며, 이중 VanA의 표현형을 보인 E. faecium 2주가 VanB의 유전형으로 판명된 것을 제외하면 표현형과 유전형은 모두 일치하였다. 플라스미드 분석과 PFGE 결과, 병원내 동일 균주의 전파 가능성이 5개 병원중 3병원에서 증명되었다. 결 론 : 국내 병원에서도 vancomycin 내성 유전자를 갖는 VRE가 다수 분리되고 있음을 확인할 수 있었으며, 연구 결과 일부 병원에서 내성균주의 병원내 전파 가능성을 시사하였다. 아직까지 국내에서 VRE로 인한 감여보고는 적지만 곧 임상적으로 문제가 될 것으로 판단되며, 따러서 내성균의 발생이나 확산을 억제하기 위한 노력과 감시가 필요할 것으로 생각된다. Background : Enterococci have emerged in recent years as a frequent cause of life-threatening nosocomial infections. The emergence of vancomycin-resistant enterococci(VRE) presents as an increasingly important problem particularly in the treatment and the potential dissemination of vancomycin-resistance. The purpose of this study is to determine the phenotypes and genotypes of VRE isolated from five hospitals and to study the genetic relatedness among them. Methods : Antimicrobial susceptibility patterns and amplification of vancomycin resistance genes were used for phenotyping and genotyping of 42 VRE isolates respectively. For 21 isolates with vanA or vanB gene, plasmid profiles and pulsed field gel electrophoresis(PFGE) patterns were analyzed for molecular epidemiologic study. Results : Out of 42 isolates, 21 were identified as E. faecium, 6 as E. faecalis, 2 as E. avium, and 13 as E. casseliflavus. Phenotyping showed 14 isolates as VanA(33%), 7 as VanB(17%) and 21 as VanC(50%). Genotyping resulted in 12 isolates as VanV(5 of E. faecalis and 7 of e. faecium) and 9 as VanB(all E. faecium). Genotyping results were concordant with phenotyping results except for the two E. faecium isolates of VanA which had VanB genotype. Intrahospital spread of the same strains was proven in three hospitals by plasmid profiles and PFGE analysis. Conclusion : The study demonstrated a considerable number of VRE isolates in Korea and intrahospital spread proven by molecular epidemiologic methods. Although VRE infection has been considered very are in Korea, practical guidelines including restriction of vancomycin usage and surveillance, are warranted to prevent infection and dissemination of VRE.

건강인의 비인강에서 황색포도구균의 분리와 Methicillin 내성 Staphylococcus Aureus의 항균제 감수성

김신무,정수진,정재옥,신용섭 원광보건전문대 1995 원광보건전문대학논문집 Vol.18 No.-

腎細胞癌에서 Flow Cytometry에 依한 核 DNA(Deoxyribonucleic Acid)量 測定

金瑩洙,薛鍾求 충남대학교 의과대학 지역사회의학연구소 1992 충남의대잡지 Vol.19 No.2

From cytometry was used to analyze deparaffinized primary renal cell carcinoma specimens in 27 cases of 54 renal cell carcinoma patients to evaluate deoxribonucleic acid ploidy as a predictor of disease progression and survival in the Department of Urology, Chungnam University Hospital, from January 1985 to September 1992. DNA ploidy was analyzed according to cell type, cellular differentiation, clinical stage, tumor size. The results were as followings: 1. Renal cell carcinoma was most frequent in 6th decade, and male to female ratio was 1.5:1. 2. Cell type of renal cell carcinoma were clear type(44.5%), granular cell type(33.3%), mixed cell type(11.1%) and sarcomatoid(11.1%). 3. In 27 renal cell carcinoma analyzed by flow cytometry, 16 tumors were diploid stem line and 11 tumors were aneuploid stem line. 4. In DNA ploidy according to cell type, cellular differentiation, tumor stage and tumor size, aneuploid rates were 41.7% in clear cell type, 22.2% in granular cell type, 66.7% in mixed and sarcomatoid type respectively, and 31.2% in low stage tumor and 54.5% in high stage tumor, and 31.2% in high differentiated group and 54.5% in low differentiated group, and 20.0% in smaller than 5cm, 41.7% in 5-10cm and 50.0% in larger than 10cm in diameter(p>0.05). 5. In mortality according to cell type, cellular differentiation, tumor stage and DNA ploidy, 6 patients were died within 5 years in clear cell type(12 cases), 4 patients were died within 2 years in granular cell type(9 cases) and 2 patients were died within 1 year in sarcomatoid type(3 cases), and 6 patients were died within 5 years in highly differentied group(16 cases) and 6 patients were died within 2 years in low differentiated group(11 cases), and 5 patients were died within 5 years in low stage(16 cases) and 7 patients were died within 2 years in high stage(11 cases), and 6 patients were died within 5 years in diploid group(16 cases) and 6 patients were died within 2 years in aneuploid group(11 cases)(p>0.05).

良好한 照明이 우리 生活에 미치는 影響

金正洙,李鍾夏,徐相壽 忠州大學校 1968 한국교통대학교 논문집 Vol.2 No.-

In this paper ; I examined the condition for proper illumination with the study of its influence on our daily life and our health, and of the ideal illumination of our houses, buildings and facfories, on the standpoint of human engineering and I made an attempt to study on these problems through the examination in the influence of proper illumination on our sight, with one thousand children of the fourth, the fifth, and the sixth grade of the primary school in the city of Chungju as an object of the study.

각종 분유내의 불소 농도와 영아 불소 섭취에 관한 연구

김정욱,손동수,김종철 大韓小兒齒科學會 1995 大韓小兒齒科學會誌 Vol.22 No.1

Since the effect of fluoride on the dental caries was known, the fluoride supplement has been recommended when the natural fluoride is unavailable or below the optimal range. On the other hand, it is well known that the overdose of fluoride results in acute and chronic toxicity, expecially dental fluorosts. So, to estimate the fluoride intake of the infant and the need of fluoride supplementation, the author measured the fluoride concentration of some bottled waters, human milk, cow'a milk, and baby formula diluted with distilled deionized water and 0.8 ppm fluoride water, by means of the modified HMDS diffusion method and the fluoride ion specific electrode. The obtained results were as follow : 1. The fluoride concentration of the soy-based infant formula was 0.25±0.10 ppm, and that of milkbased infant formula was 0.05±0.02 ppm. The difference in the fluoride concentration between the soy-based and the milk-based infant formula was statistically significant(p<0.01). 2. In the case that the infant is fed with the human milk and /or cow's milk exclusively, appropriate fluoride supplementation is needed regardless of the fluoride concentration of the municipal water. 3. The fluoride intake seems to be optimal when the infant is fed with some soy-based infant formula even though the municipal water is not fluoridated. In that case fluoride supplementation is unnecessary. But fluoride supplement is needed when the infant is fed with milk-based baby formula in the nonfluoridated area. 4. The fluoride intake of the infant is beyond the optimal range when the infant is fed with baby formula diluted with the fluoridated municipal water.

자기구성 퍼지 제어기법에 의한 수직다관절(AMI)로봇의 위치 및 속도 제어

김종수,배길호,한성현 경남대학교 공업기술연구소 2000 硏究論文集 Vol.18 No.-

본 연구에서는 산업용 로봇 시스템의 정밀도 및 견실성을 향상시키기 위하여 자기구성 퍼지제어 알고리즘을 개발하여 디지털 신호 처리기에 기초한 관절제어기를 설계하고 이의 실시간 제어실현에 대한 연구가 수행되었다. 제안된 자기구성 퍼지 제어기는 적절한 제어입력을 출력하면서 환경을 관측하고 이 제어입력으로 인한 결과를 이용하여 다음에 나올 결과를 향상시킨다. 그러므로 자기구성 퍼지 제어기를 이용하면 환경에 대한 최소의 정보만을 가지고도 견실 제어기를 설계할 수 있다. 본 논문에서는 조정인자와 규칙을 동시에 수정하여 제어규칙이 점근적으로 수렴하면서 수렴속도를 향상시킬 수 있는 자기구성 퍼지 제어기를 제안하였다. 제안된 자기구성 퍼지 제어기는 위에서 언급한 바와 같이 퍼지 제어기의 단점을 보완하는 측면이 있기 때문에 성능향상을 기대할 수 있다. 따라서, 본 논문에서는 퍼지추론기능과 퍼지규칙 조정능력을 갖는 퍼지 알고리즘을 개발하고 외부환경의 변화 즉, 제어대상인 플랜트의 파라미터변화 및 부하의 변동에 대해서도 능동적이고 우수한 제어성능이 유지될 수 있는 고정도 산업용 로봇 제어기 설계기법을 제안하고, 수직다관절(AM1)로봇에 대한 시뮬레이션 및 실험을 통해 그 성능을 검증하였다. In this paper, it is presented a new technique to the design and real-time implementation of fuzzy control system based-on digital signal processors in order to improve the precision and robustness for system of industrial robot. Fuzzy control has emerged as one of the most active and fruitful areas for research in the applications of fuzzy set theory, especially in the real of industrial processes. In this thesis, a self-organizing fuzzy controller for the industrial robot manipulator with a actuator located at the base is studied. A fuzzy logic composed of linguistic conditional statements is employed by defining the relations of input-output variable of the controller, In the synthesis of a FLC, one of the most difficult problems is the determination of linguistic control rules from the human operators. To overcome this difficult, SOFC is proposed for a hierarchical control structure consisting of basic level and high level that modify control rules.

성장기 아동에서의 기능성 전치부 개교의 치료증례

김종철,장기택,손동수,김주훈 大韓小兒齒科學會 1996 大韓小兒齒科學會誌 Vol.23 No.3

Anterior openbite is defined as the lack of contacts between the functional occluding teeth on vertical line at centric occlusion and classified into functional and skeletal anterior openbite based on its causes and characteristics. Anterior openbite causes masticatory, speech, and esthetic problems in the growing children and difficulties in diagnosis, treatment, and the prediction of its prognosis. We are reporting on the treatment of anterior openbite in the growing children and the results follow as : 1. In the growing children with anterior openbite, the overbite could be increased by the treatment according to its causes and characteristics. 2. The prognosis is not determined by the presence or severity of oral habit but the skeletal tendency of the patient.