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Combinatory RNA-Sequencing Analyses Reveal a Dual Mode of Gene Regulation by ADAR1 in Gastric Cancer
Cho, Charles J.,Jung, Jaeeun,Jiang, Lushang,Lee, Eun Ji,Kim, Dae-Soo,Kim, Byung Sik,Kim, Hee Sung,Jung, Hwoon-Yong,Song, Ho-June,Hwang, Sung Wook,Park, Yangsoon,Jung, Min Kyo,Pack, Chan Gi,Myung, Seun Springer-Verlag 2018 Digestive diseases and sciences Vol.63 No.7
Soft toric lens rotation measurement using Slit-lamp method and built-in camera of smart phone
Sung Woo Choi,Min Gi Lee,Chan Wok Lee,Sang Min Choi,Mi Ae Park,Jung Gun Lee,Sun Mi Park,Hyung Min Park,Byoung Sun Chu 대한시과학회 2015 대한시과학회지 학술대회 Vol.2015 No.10
Purpose: Aims of this study were to investigate the agreement and test-retest repeatability of two methods for measuring magnitude of soft toric lens rotation. The two methods assessed were a newly developed mobile application for iPhone which uses the built-in camera function and the slit lamp biomicroscope. Methods: Agreement of ToriExpertä against known reference source was tested under experimental situation. For clinical measurement, thirty three participants (66 eyes) wore toric lens (prism ballast design) both eyes. Two investigators measured toric lens rotation using the two methods which are slit-lamp measurement(HS-700) and mobile application. First investigator used the same method twice for assessment of test-retest repeatability of each method. Inter- and intra-investigator agreement and repeatability were assessed using Bland-Altman analysis. Results: Against the known reference sources, mean variance was 0.52±0.75 degree and limits of agreement was ±1.47 degree (95% of Cls). The limits of agreement between the silt-lamp biomicroscope and mobile application methods was ±9.1 degree (95% CIs). Measurements using the two different methods showed no statistically significant mean difference (paired t-test, p=0.32). Inter-investigator agreement of lens rotation was ±7.9 degree (95% CIs) using the slit-lamp microscope and ±7.8 degree using mobile application. Intra-investigator repeatability was ±6.6 degree using the slit lamp microscope and ±6.8 using mobile application. Conclusions: The results should be considered in view of the fact that soft toric lenses are not static but move with the blink thus the location of the reference point is unlikely to be at exactly the same location at the different measurement times. Despite this source of variability in the results, the newly developed mobile application provides clinically comparable performance to slit lamp biomicroscope measurement which does not appear to be investigator dependent. This mobile application may provide sufficient precision to those optometric practices have limited access to slit-lamp biomicroscope for measuring soft toric lens rotation.
Cho, Min Soo,Kim, Sung Hoon,Park, Seung Woo,Lim, Jin Hong,Choi, Gi Hong,Park, Joon Seong,Chung, Jae Bock,Kim, Kyung Sik Quality Medical Pub 2012 Journal of gastrointestinal surgery Vol.16 No.9
<P>The surgical resection of hilar cholangiocarcinoma is extremely challenging because the tumor is closely related with the complicated hilar structures. We investigated to identify the outcomes for patients who underwent surgical resection and to identify the parameters that influenced radical resection.</P>