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홍혜경 한국교육학회 2001 敎育學硏究 Vol.39 No.2
본 연구는 유아의 기하학적 공간관계에 대한 구체적 표상능력과 영상적 표상 능력에 있어 표상매체, 연령, 성별에 따른 발달적 특징을 밝히고자 하였다. 기하학적 공간관계에 관한 표상에 대하여 유아들은 사진이나 입체 그림의 제시를 구체물로 표상하는 경우가 구체물 제시를 사진이나 입체그림으로 표상하는 경우보다 더 어려워 하였으며, 표상매체가 사진인 경우 입체그림보다 표상이 쉬운 것으로 나타났다. 또한 유아의 기하학적 공간에 대한 이해의 표상은 연령에 따라서 의미있는 차이를 보인 반면 성별에 있어서는 의미 있는 차이를 보이지 않았다. 한편, 제시관점에 따른 유아의 표상능력은 정면 관점, 평면 관점, 측면 관점의 순으로 나타났으며, 연령에 따라서도 차이를 보였다. 본 연구는 유아교육 현장에서 유아의 표상능력을 지원하기 위하여 다양한 구성놀이에 그림이나 사진 등의 영상적 표현을 구체물로 표상하는 교육활동의 적극적 활용의 필요성을 시사하고 있다.
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유아 수학교육과정에 관한 비교적 고찰 : 한국, 미국, 구소련을 중심으로
홍혜경 한국유아교육학회 1994 유아교육연구 Vol.14 No.1
The purpose of this study was to compare the mathematics curriculum of the first grade and kindergarten of the United States, the Soviet Union and Korea. Because the educational goals and systems of the three countries are different, the comparison of the mathematics curriculum focused only on the contents and scope. The National math curriculum of Korea and the Soviet Union and the High School math curricula and Harper & Row math curricula of the United States were analyzed. The findings from content analysis indicated that the math curriculum of the United States and the Soviet Union had better continuity and sequence from the kindergarten to the first grade in terms of content and scope than that of Korea. The math. curriculum of the United States covered broader content areas, such as estimation, computer and statistics than those of the two other countries. The math curriculum of the Soviet Union dealt with number, measurement, and spatial relation in more depth and by a more systematic approach than those of the two other countries. The math curriculum of Korea had discontinuity in content and scope from kindergarten to the first grade but covered more content areas, such as seriation and number sense.
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양극성 장애 환자에서 월경 주기에 따른 증상과 Lithium농도의 변화
홍혜경,정희연,권영준,김현 大韓神經精神醫學會 2004 신경정신의학 Vol.43 No.4
Objectives : It was reported that symptoms change according to menstrual cycles, aggravation of symptoms 3to 7 days before menstruation in bipolar disorder for example. Therefore, this study was to investigate the correlation among the change ofsymptoms, serum lithium level, estradiol and progesterone levels. Methods : For women with bipolar disorder, we divided by menstrual cycle into three groups ; middle foUicular phase, middle luteal phase and late luteal phase. We estimated semm lithiumlevel, estradiol and progesterone of each phase, and assessed the change of symptoms using Hamilton Rating Scale for Depression and Manic-State Rating Scale. Consequently they were divi-ded into symptom changed group and not changed group. Results : Serum lithium levels of patients with bipolar disorder were significantly decreased in middle luteal phase compared with in middle follicular phase, and it was sustained in low level to late follicular phase. Although there were no statistically Signi-ficant differences, there was more decreased semm lithium level in symptom changed group than in symptom unchanged group. Serum lithium levels were not statistically correlated with both estradiol and progesterone levels. When symptom changed group was compared with symptom not changed group, there was a significant correlation between changes of symptom and estradiol level. Conclusion : The possible mechanism of the change of symptoms according to menstrual cycle in bipolar disorder may be in estrogen level and due to the effect of serum lithium level change according to menstrual cycle. The investigation of this mech-anism will contribute to the treatment and the prevention of recurrence symptons in bipolar disorder.
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정상 및 종양성 결장상피세포의 인체 융모막성 고나도트로핀 생성에 관한 면역세포화학적 연구
홍혜경,염범우,이대일 고려대학교 의과대학 1988 고려대 의대 잡지 Vol.25 No.1
Human beta chorionic gonadotropin (β-HCG), which is an essential hormone for the continuance of pregnancy, is one of tumor marker of greatest use, nowaday. Beside its nearly exclusive production by trophoblastic epithelium of the placenta under normal circumstances, the hormone also may be secreted into the blood by trophoblastic tumor as well as germ cell tumors of the testes and ovaries. Other tumors have been reported to be associated with elevated β-human chorionic gonadotropin (β-HCG) levels, but the serum concentration rarely exceeds 10ng/mL. However, immunoenzyme histochemical staining can detect presence of β-HCG in the non-trophoblastic tumor at cellular level. The author selected fromalin fixed and paraffin embedded tissue sections of normal, benign and malignant lesions of the colon and examined β-HCG in these specimens to understand pattern of distribution of this hormone in each group. The results are as followings; 1. There was no β-HCG containing cells in normal colonic mucosae, non-neoplastic epithelial polyps and adenomas of colon. 2. Thirteen cases (48.1%) of 27 colonic adenomocarcinomas showed sporadic β-HCG positive tumor cells along the lining cells of the tumor glands. 3. β-HCG positive cells were found in 60% of well differentiated, 50% of moderately differentiated, none of poorly differentiated carcinoma and 40% of mucous carcinomas. 4. Distribution of β-HCG were intracytoplasmic and granular in moderate degree and the degree of reactions were especially intense at the site of deep intramuscular invasion of the colon. 5. Among 12 cases of metastatic lesions, β-HCG reactive cells were found in 7(58.3%) cases. Above results suggest that distribution of β-HCG positive cells in colon is restricted only to carcinoma cells in sporadic, granular and intracytoplasmic pattern in almost an half of cases. And positivity of β-HCG in colon cancer seems to have no relationship in both degree of differentiation or invasiveness of the tumor cell.
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홍혜경 한국영유아보육학회 1998 한국영유아보육학 Vol.0 No.16
본 연구는 유아와 어머니 및 교사의 이야기책 읽기 형태를 유형화하고, 그 유형별 특성을 분석하며, 책의 친숙 정도에 따른 유형별 차이를 비교하고자하였다. 이야기책 읽기 유형화를 위해 실시한 군집분석 결과는 다음과 같다. 첫째, 유아-어머니의 이야기책 읽기 유형은「설명-반응형」과「이해-확장형」으로 분류되었고, 유아-교사의 이야기책 읽기 유형은「설명-반응형」,「이해-확장형」,「참여-유도형」으로 분류되었다. 둘째, 책의 친숙 정도에 따라서는 어머니가 이야기 책 읽기 유형에 차이를 보인 반면 교사는 이야기책 읽기 유형별 분포에서 차이를 보였다.
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