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대학생의 자기개념 명확성과 스트레스 대처방식이 우울에 미치는 영향
탁은영,박주희 한국생애학회 2019 생애학회지 Vol.9 No.2
The present study examined the effects of self-concept clarity and stress coping styles on depression in undergraduate students, and whether stress coping styles moderated the relation between self-concept clarity and depression. The participants of this study were 355 students (145 males and 209 females) from 15 universities located in Seoul and Gyeonggi-do. To measure the level of depression, the Center for Epidemiological Studies-Depression(CES-D) Scale was used. The level of self-concept clarity was assessed by the Self-concept Clarity Scale. Also, stress coping styles were measured by Coping Styles Inventory. The data was analyzed by means of descriptive statistics and hierarchical regressions. The moderating effects of stress coping styles were investigated using the analysis procedures proposed by Baron and Kenny . The results indicated that the levels of self-concept clarity and problem-focused coping decreased the level of depression. Moreover, problem-focused coping, emotion-focused coping and aesthetic thinking moderated the effects of self-concept clarity on depression.
이상화,탁은영,조유정,Jiye Kim,이주영,이륜진,이관희,권민성,윤영인,이성규,남궁정만,김준기 한국바이오칩학회 2022 BioChip Journal Vol.16 No.1
During living donor liver transplantation, a number of blood vessels and bile ducts are anastomosed while the liver and gallbladder are resected in the donor and recipient. Early detection and treatment of complications after surgery by evaluating the function of blood vessels and the biliary tract is crucial. A biosensing chip that can monitor patient health status from the bile excreted during the recovery process has been developed using a surface-enhanced Raman sensing chip. Surface-enhanced Raman spectroscopy signals of bile obtained from normal bile duct ligation and gallbladder damage mouse models using a cautery device were identified and analyzed. The surface-enhanced Raman chip with a nanometer-level porous structure can selectively separate the nanometer biomarkers and measure the Raman signal. Through the detection of nanometer biomarkers in the bile and comparative analysis of histopathology, the Raman signal in the damaged gallbladder was compared with that caused by liver damage due to bile duct ligation, showing that it becomes a biosensing chip for monitoring recovery.
Lim So Yun,Yoon Young-In,Ji Yeun Kim,탁은영,권현욱,Sung Shin,Kim Young Hoon,Song Gi-Won,Kim Sung-Han,Lee Sung-Gyu 대한이식학회 2023 Korean Journal of Transplantation Vol.37 No.1
Background: Solid organ transplant recipients exhibit decreased antibody responses, mainly due to their weakened immune systems. However, data are limited on antibody responses after the primary series of coronavirus disease 2019 (COVID-19) vaccines among recipients of various solid organ transplant types. Thus, we compared the antibody responses after three COVID-19 vaccine doses between liver transplant (LT) and kidney transplant (KT) recipients. Methods: We prospectively enrolled solid organ transplant recipients who received three COVID-19 vaccine doses from June 2021 to February 2022 and measured S1-specific immunoglobulin G antibodies using an enzyme-linked immunosorbent assay. Results: Seventy-six LT and 17 KT recipients were included in the final analysis. KT recipients showed consistently lower antibody responses even after the third vaccine dose (86.2% vs. 52.9%, P=0.008) and lower antibody titers (median, 423.0 IU/mL [interquartile range, 99.6–2,057 IU/mL] vs. 19.7 IU/mL [interquartile range, 6.9–339.4 IU/mL]; P=0.006) than were observed in LT recipients. Mycophenolic acid was a significant risk factor for a seropositive antibody response after the third vaccine dose in the multivariable analysis (odds ratio, 0.06; 95% confidence interval, 0.00–0.39; P=0.02). Conclusions: We found a weaker antibody response despite the completion of the primary series of COVID-19 vaccines in KT recipients than in LT recipients. Mycophenolic acid use in KT recipients might be the main contributor to this observation.