규칙적인 수영운동과 taurine 섭취가 Seizure 유발 마우스의 해마에서 항산화 효소 및 caspase-3, 8 발현에 미치는 영향

채창훈(Chae Chang-Hun),노종철(Noh Jong-Cheol),이진경(Lee Jin-Kyung),강성환(Kang Sung-Hwan),박석(Park Sok),김현태(Kim Hyun-Tae),박종명(Park Jong-Myoung),안응남(An Eung-Nam),김지연(Kim Ji-Youn) 한국체육과학회 2010 한국체육과학회지 Vol.19 No.2

We investigated changes in the activity of inducing epileptic seizures with PTZ, changes in apoptosis-related factors and the antioxidant defense system in mice. The mice were divided into 4 groups (n=8 for each group) such as the control (PTZ) group, the carnosine-administered (Ca+PTZ) group, the exercise (Ex+PTZ) group and the mixed treatment (Ca+Ex+PTZ) group. The expression of caspase-3, 8 protein was a significant difference in the changes of protein expression between all groups. But the changes in the activity of antioxidant enzymes were significantly different only for SOD. Based on the results above, pretreatment of carnosine and exercise was found to have a positive effect on protection against oxidative damages and excitatory toxicity which is produced in large amounts in epileptic seizures. This study reported that especially the mixed treatment of regular aerobic exercises and carnosine administration reduced the level of seizure activities and mortality by reducing the protein level of caspase-3, 8 as well as increasing antioxidant enzyme activity.

배구선수들의 포지션별 전문체력 수준에 관한 연구

채창훈(Chae Chang-Hun),권순일(Keon Soon-Il),권태원(Kwon Tae-Won) 한국체육과학회 2002 한국체육과학회지 Vol.11 No.1

The purpose of this to induce to rear for the specific physical fitness which is needed to each volleyball plater according to the position and give a model abide by it For this, Attacker(36 people), Setter(14 people), Liebero(11 people) who are all of chief players of 7 Universities entered in 2001 S Fire Insurance Cup were Subjected. Measurement Item were fixed into 25 items with below conformities. - Professionalist's Subjective Judgement - Result of the Performing Game in Every Position - Application of Test which were Demonstrated with Existing Validity 1. Muscular Strength There were no Significant differencies within the Groups in the result of Grip Strength, Back Strength, Isokinetic(60 °/sec) test. 2. Muscular Strength Endurance There were no Significant differencies within the Groups in the result of Sit-ups, Burpee, 25 Shuttle Run, Isokinetic(180 °/sec) test. 3. Cardiorespiratory Endurance There were no Significant differencies within the Groups in the result of Max Vo2/㎏ test. 4. Power There were no Significant differencies within the Groups in the result of Standin Board Jump, 50m Sprinting Run, Hand ball Throw, Isokinetic(120 °/sec) test but in the Sargent Jump test the difference within the Groups were existed. 5. Agility There were no Significant differencies within the Groups in the result of 10m Shuttle Run, Side Step, Bumerang Run, Zag Zig Run test but in the Whole Body Reaction Movement Time test(Sound, Right), the difference within the Groups were existed. 6. Flexibility There were no Significant differencies within the Groups in the result of Trunk Extension, Bridge- Up, Shoulder-Wrist test but in the Trunk Flextion test, the difference within the Groups were existed. 7. Balance There were no Significant differencies within the Groups in the result of Foot Balancein Closed Eyes, Dynamic Balance(Left & Right, Front & Back) test. In the synthesis above results, the items in which the difference within the groups were not existed were needed with measurement items in the three groups, in the case of the groups within which the difference were existed, only the item is needed to rearing specific physical fitness in the subjected position. Therefore, Rearing specific physical fitness every player's position. Not for Volleyball player's but for other collective game and personal game, and the detailed physical fitness rearing, the appropriate position must be fixed after grasping physical distinction, and it is supposed that a training program to elevate physical fitness needed in the personal position will be provided, and it is thought that for an objective and scientific basic data, accurate measurement and valuation and appropriated conformity fixation about sports item should be achieved.

대규모 안전교육 가상훈련을 위한 통합제어 시스템 개발

채창훈(Chang-hun Chae),윤여훈(Yeo-hun Yoon) 대한전기학회 2024 대한전기학회 학술대회 논문집 Vol.2024 No.7

Preconditioning으로서의 운동이 탈진적 운동시 항산화 기능 및 운동수행능력에 미치는 효과

채창훈(Chae Chang-Hun),이상규(Lee Sang-Kyu),박석(Park Sok) 한국체육과학회 2010 한국체육과학회지 Vol.19 No.2

The effects of exercise as preconditioning on antioxidant function and exercise performance ability at during maximal exercise are pooly understood This study was investigated the exercise as preconditioning on antioxidant function and exercise performance ability. Mail sprague-Dawley rats(n=24) were randomly divided into the following 3 groups; (1) none preconditioning group(CON: n=8), (2) exercise as preconditioning for 10 minute (Pre 10min: n=8), (3) exercise as preconditioning for 20 minute (Pre 20min: n=8), Rats were subjected to swimming exercise for 5days a week for 4weeks before maximal exercise. At the end of exercise as preconditioning period, rats were performanced maximal exercise. We got the following result for antioxidant function and maximal exercise performance effect by exercise as preconditioning. In rats with skeletal muscle(gastrocnemius) induced SOD, CAT activity and reduced MDA concentration. In addition, exercise performance time were increased. These result suggest that exercise as preconditioning in the animal model, may be useful to improve antioxidant function and exercise performance ability.

Caspase-3 활성 억제를 위한 DL-α-lipoic acid 효과

채창훈(Chae Chang-Hun),김근영(Kim Kuen-Young) 한국체육과학회 2006 한국체육과학회지 Vol.15 No.1

We investigated the effect of short-term supplementation with α-lipoic acid on MDA and vitamin E concentration and caspase-3 activity in gastrocnemius, during exhaustive treadmill exercise. Forty male SD rats were randomized to α-lipoic acid supplementation group(n=:rn and control group(n=20). α-lipoic acid(100㎎/㎏; Sigma, St. Louis, MO, USA; vehicle=com oil) was administered orally every day for 5 days. Exercise consisted of a single treadmill bout(28-30m/min, grade 5%) condition. MDA concentration was significantly lower in the a -lipoic acid supplementation group compared to the control group in exercise 30min, post-exercise. vitamin E concentration was significantly increase in the lipoic acid supplementation group compared to the control group in exercise 30min, post-exercise and recovery 3hour. Caspase-3 activity was significantly lower in the α-lipoic acid administration group compared to the control group in post-exercise, recovery 3hour. The results suggest that exhaustive treadmill exercise are increase MDA concentration and redues vitamin E concentration and increase caspase-3 activity. But α-lipoic acid supplementatuon reduces the lipid peroxidation and increase the vitamin E concentration and inhibits the caspase-3 activity in gastrocnemius.

노화과정 백서의 심장에서 산화스트레스 및 caspase-3 활성도에 미치는 운동과 ALA 효과

채창훈(Chae Chang-Hun),김현태(Kim Hyun-Tae) 한국체육과학회 2007 한국체육과학회지 Vol.16 No.3

The purpose of this study was to investigate the effect of regular aerobic exercise and DL-α-lipoic acid(ALA) supplementation for 8 weeks on Hydrogen peroxide, MDA and Vitamin E concentrations and caspase-3 activity in induced aging rats heart by D-galactose ingestion(50mg/kg). The rats were randomly assigned to one of the following four groups(n=8 per group): 1) control group(CON) 2) aging control group(A-CON) 3) aging exercise group(A-EX) 4) ALA supplementation group(A-ALA) 5) exercise training with ALA supplementation group(A-EA). Ageing rats were induced by injecting D-galactose(50mg/kg dissolved in 0.1ml dilution water) every day for 8 weeks excluding control group. ALA(100mg/kg) was supplemented orally every day for 8 weeks. The exercise program regime consisted of running on a treadmill at an increasing pace. Hydrogen peroxide and MDA concentrations were significantly lower in the A-EX, A-ALA, A-EA groups compared with A-CON group. Vitamin E concentration was significantly lower in the A-EA groups compared with other groups, but not GSSG level. Caspase-3 activity was significantly decrease in the A-ALA, A-EA groups compared with other groups, and caspase-3 activity in A-ALA, A-EA groups was similar with CON group. These results suggest that regular exercise combined with ALA supplementation can offer beneficial effects of prevent lipid peroxidation and apoptosis in D-galactose induced aging rats heart.

다중 시스템에서 물리 시뮬레이션을 위한 AR 환경의 동기화

채창훈 ( Chang-hun Chae ),고광희 ( Kwang-hee Ko ) 한국정보처리학회 2009 한국정보처리학회 학술대회논문집 Vol.16 No.2

본 논문에서는 증강현실 환경에서 다중 시스템의 물리 시뮬레이션을 위한 동기화 방법을 제안한다. 증강현실 시스템의 몰입감 증대를 위하여 가상 객체에 물리 법칙에 기반을 둔 실질적인 움직임을 부여하는 방법을 논하고 이를 네트워크로 확장하기 위하여 물리 기반 증강현실 환경의 동기화 방법을 연구하였다. 이러한 연구를 통하여 증강현실 어플리케이션의 몰입감 증대와 네트워크 게임에서의 증강 현실 도입이라는 새로운 방향도 제시 할 수 있을 것이다.

효과적인 SCL 엔지니어링 툴 설계를 위한 관련 S/W 툴 분석

채창훈 ( Chang-hun Chae ),정남준 ( Nam-joon Jung ),최효열 ( Hyo-yul Choi ),안용호 ( Yong-ho An ) 한국정보처리학회 2012 한국정보처리학회 학술대회논문집 Vol.19 No.1

본 논문에서는 국내외 선진회사의 SCL 엔지니어링 툴에 관한 연구를 진행하였다. 최근 전력산업이 디지털화 되면서, 변전소자동화에 관련된 국제 표준인 IEC61850은 필수 요소로 자리 잡았다. 따라서 IEC61850 표준에서 사용하는 SCL파일들을 생성, 수정하고, 각종 서비스들을 규정하는 SCL 엔지니어링 작업은 필수적이다. 하지만, 현재 벤더중심, 해외위주의 엔지니어링 툴만이 대부분이기 때문에 국내 실정에 맞는 디지털변전소 엔지니어링 툴을 개발하는 것이 시급하다. 따라서 본 연구는 여러 가지 관점에서 선진 툴들을 분석하고, 분석내용을 토대로 SCL 엔지니어링 툴의 필수 기능들을 도출하고, 사용자 중심의 편의성 높은 엔지니어링 툴을 설계하는 것을 목표로 한다.

L-Carnosine과 규칙적인 운동의 항산화적 효과

채창훈 ( Chang Hun Chae ),안응남 ( Eung Nam An ) 한국운동영양학회 2005 Physical Activity and Nutrition (Phys Act Nutr) Vol.9 No.1

The purpose of this study was to investigate the effect of long-term L-Carnosine Intake and regular aerobic exercise on blood MDA concentration and SOD, GPx, CK, LDH activity, regarding oxidative stress during exercise test for 30min (running at 16-17min). The rats were assigned randomly to 4 groups (control, n = 7; camosine intake, n = 7; exercise, n = 7; exercise + camosine intake, n = 7). Each regimen was 8 weeks long. MDA concentrations in exercise + camosine intake group was significantly lower compared to control group. SOD activity in exercise + carnosine intake group was significantly higher compared to the groups. GPx activity in exercise + camosine intake group was significantly higher compared to control group. CK activity in exercise and camosine intake, exercise + carnosine intake groups was lower compared to control group. LDH activity in exercise + carnosine intake group was significantly lower compared to the groups. These results indicated that long-time regular aerobic exercise and camosine intake may inhibit lipid peroxidation to oxidative stress and increase activity of SOD and GPx, but not CK and LDH

운동형태에 따른 고도비만 여성의 신체구성 및 혈장 C-reactive protein의 변화

채창훈 ( Chang Hun Chae ),유병강 ( Byung Kang You ),김현태 ( Hyun Tae Kim ) 한국운동영양학회 2005 Physical Activity and Nutrition (Phys Act Nutr) Vol.9 No.2