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      • 전립선암 환자의 복부압박에 따른 표적 움직임 분석

        오정훈,정건,정원석,조준영,김기철,최태규,Oh, Jeong Hun,Jung, Geon A,Jung, Won Seok,Jo, Jun Young,Kim, Gi Chul,Choi, Tae Kyu 대한방사선치료학회 2014 대한방사선치료학회지 Vol.26 No.1

        목 적 : 외부 압박을 통해 전립선암 환자의 복강 내 압력을 안정화시켜 움직임을 감소하여 치료 간(interfraction)과 치료 중(intrafraction)에 변화를 측정하여 평가하고자 시행하였다. 대상 및 방법 : 10명의 전립선환자들은 전체 치료과정동안 MVCT 스캔을 통해 치료 전과 후에 걸쳐 환자 당 60개의 영상을 획득하였고 획득한 좌우방향(X), 상하방향(Y), 전후방향(Z), 회전방향(Roll)에 대한 Shift 값들을 이용하여 복부 압박 시 치료 간 치료준비 변화와 치료 중 표적 움직임의 상호 연관성을 분석하였다. 결 과 : 치료 간의 움직임 변화는 평균 좌우방향(X)에서 $0.65{\pm}2.32mm$, 상하방향(Y)에서 $1.41{\pm}4.83mm$, 전후방향(Z)에서 $0.73{\pm}0.52mm$, 회전방향(Roll)에서 $0.96{\pm}0.21^{\circ}$로 나타났다. 치료 중 움직임 변화는 평균 좌우방향(X)에서 $0.15{\pm}0.44mm$, 상하방향(Y)에서 $0.13{\pm}0.44mm$, 전후방향(Z)에서 $0.24{\pm}0.64mm$, 회전방향(Roll)에서 $0.1{\pm}0.9^{\circ}$로 나타났다. 결 론 : 전처치과정과 외부에서 복부압박을 통한 전복부의 움직임을 제한한다면 치료동안에 내부 장기와 환자의 움직임을 감소시켜 보다 적은 여유(margin)로 계획용 표적체적(PTV)을 생성할 수 있어서 정상조직의 부작용 증가 없이 더욱 이상적인 선량 체적을 얻을 수 있을 것으로 사료된다. Purpose : To evaluate the changes of the motion of abdominal cavity between interfraction and intrafraction by using abdominal compression for reducing abdominal motion. Materials and Methods : 60 MVCT images were obtained before and after tomotherapy from 10 prostate cancer patients over the whole radiotherapy period. Shift values ( X -lateral Y -longitudinal Z -vertical and Roll ) were measured and from it, the correlation of between interfraction set up change and intrafraction target motion was analyzed when applying abdominal compression. Results : The motion changes of interfraction were X-average $0.65{\pm}2.32mm$, Y-average $1.41{\pm}4.83mm$, Z-average $0.73{\pm}0.52mm$ and Roll-average $0.96{\pm}0.21mm$. The motion changes of intrafraction were X-average $0.15{\pm}0.44mm$, Y-average $0.13{\pm}0.44mm$, Z-average $0.24{\pm}0.64mm$ and Roll-average $0.1{\pm}0.9mm$. The average PTV maximum dose difference was minimum for 10% phase and maximum for 70% phase. The average Spain cord maximum dose difference was minimum for 0% phase and maximum for 50% phase. The average difference of $V_{20}$, $V_{10}$, $V_5$ of Lung show bo certain trend. Conclusion : Abdominal compression can minimize the motion of internal organs and patients. So it is considered to be able to get more ideal dose volume without damage of normal structures from generating margin in small in producing PTV.

      • MVCT를 이용한 치료 간(Interfraction) 그리고 치료 중(Intrafraction) 내부 장기 변화 분석

        정원석,김주호,김영재,신령미,오정훈,정건,조준영,김기철,최태규,Jung, Won Seok,Kim, Ju Ho,Kim, Young Jae,Shin, Ryung Mi,Oh, Jeong Hun,Jeong, Geon A,Jo, Jun Young,Kim, Gi Chul,Choi, Tae Kyu 대한방사선치료학회 2014 대한방사선치료학회지 Vol.26 No.1

        목 적 : 다양한 치료 부위에 따라 MVCT(Megavoltage computed tomography)를 이용하여 치료 중(Intrafraction), 치료 간(Interfraction)의 장기 위치 변화를 측정하여 평가하고자 한다. 대상 및 방법 : 본 연구에서 두 경부(Head & neck), 흉부(Thorax), 간(Liver), 전립선(Prostate) 종양을 가진 48명 환자들은 전체 치료 과정동안 다양한 MVCT scan을 시행하였다. 평균 환자 당 60개의 MVCT 영상을 획득하여 분석하였다. 결 과 : 치료 간(Interfraction)오차는 흉부와 복부 그리고 골반이 종 방향(Longitudinal, Y)에서 3 mm 이상의 차이를 보였다. 치료 중(Intrafraction) 변화를 알아보기 위해 치료가 끝난 후에 MVCT를 찍어 확인한 후 치료 중(Intrafraction) 움직임 차이는 종 방향에서 2 mm 내외로 나타났다. 또한 치료 전과 후의 움직임의 변화로 인해 치료 간 그리고 치료 중의 차이를 확인하였다. 결 론 : 본 연구에서도 두 경부(Head & neck), 흉부(Thorax), 간(Liver), 전립선암(Prostate cancer) 환자들의 치료 간(Interfraction) 변화와 치료 중(Intrafraction)변화를 통해 적절한 고정 기구와 표적 여백의 윤곽을 완성하는데 도움이 될 거라 사료된다. Purpose : Depending on a variety of therapeutic areas using MVCT(Megavoltage computed tomography) intra-and interfraction is to evaluate changes in patient position. Materials and Methods : In this study, head and neck, thorax, liver, and prostate tumor patients, 48 people with a full course of treatment for patients with various MVCT scan was performed. Average 60 per patient MVCT images were acquired and analyzed. Results : Interfraction error thorax and abdomen, and pelvis in the longitudinal difference was more than 3 mm. Intrafraction to see a change after the end of treatment MVCT taken, and the results confirmed Intrafraction 2 mm in motion around the longitudinal difference. In addition, due to changes in the movement before and after treatment, Inter-and Intrafraction difference was found. Conclusion : In the present study, the Head and Neck, Thorax, liver, prostate cancer in patients with inter-and intrafraction changes and target the appropriate fixtures to complete the outline of the margin would be helpful is considered.

      • 환자 자세가 간의 방사선 치료 시 선량에 미치는 영향

        정원석,김주호,김영재,신령미,오정훈,정건,조준영,김기철,최태규,Jung, Won Seok,Kim, Ju Ho,Kim, Young Jae,Shin, Ryung Mi,Oh, Jeong Hun,Jeong, Geon A,Jo, Jun Young,Kim, Gi Chul,Choi, Tae Kyu 대한방사선치료학회 2014 대한방사선치료학회지 Vol.26 No.1

        목 적 : 간암 치료 시 호흡으로 인한 움직임을 최소화하기 위해 환자 체위 변화에서 종양의 움직임과 용적 변화를 분석하고자 하였다. 대상 및 방법 : 간 세포암종(Hepatocellular Carcinoma) 환자 14명의 환자를 대상으로 시행하였다. 바로 누운 자세(Supine position)와 엎드린 자세(Prone position)에서 2가지 방법으로 환자 고정기구를 제작하고 영상을 획득하여 간 종양의 움직임과 용적 그리고 선량을 분석하였다. 결 과 : 바로 누운 자세(Supine position)와 엎드린 자세(Prone position) 에서 표적의 왼쪽-오른쪽(LR, Left-right) 움직임은 평균 $2.76{\pm}1.25mm$, $2.21{\pm}0.93mm$이고, 앞-뒤(AP, Anterior-posterior)와 상하(SI. Superior-inferior) 방향의 움직임은 각각 $4.02{\pm}1.63mm$, $11.56{\pm}3.08mm$, $3.36{\pm}1.17mm$, $7.45{\pm}1.96mm$이었다. 이를 이용한 엎드린 자세(Prone position)에서 치료 용적(Treatment volume)은 감소하였고, 이에 따라 정상간 용적은 증가 하였다. 결 론 : 호흡에 의한 간의 움직임을 최소화함으로써 치료 용적(Treatment volume)의 경계여유를 감소시킬 수 있었다. 즉 환자 자세 변화 특히 엎드린(Prone) 자세는 간의 움직임을 감소 시켜주고 정상 간의 용적을 증가 시킬 수 있을 것으로 사료된다. Purpose : To analyze tumor's movement and volume change from changing position in order to minimize movement caused by breathing. Materials and Methods : We conducted survey of 14 patients with HCC(Hepatocellular carcinoma). Patient immobilization device was made in two ways(Supine position, prone position) and from image acquisition, tumor's movement, volume and dose are analyzed. Results : The mean movement of target(LR, Left-right) in supine position and prone position was $2.76{\pm}1.25mm$, $2.21{\pm}0.93mm$. AP(Anterior-posterior) and SI(Superior-inferior) was $4.02{\pm}1.63mm$, $11.56{\pm}3.08mm$, $3.36{\pm}1.17mm$, $7.45{\pm}1.96mm$. Treatment volume was decreased and normal liver volume was increased in prone position. Conclusion : We could reduce the margin of the treatment volume by minimizing the movement of liver caused by breathing. Especially in prone position, it is considered to be able to decrease the movement of the liver and increase normal liver volume.

      • KCI등재후보

        삼위일체 하나님의 은혜의 경륜 안에서 신실한 성경읽기

        정건(Jung, Gun) 개혁신학회 2009 개혁논총 Vol.12 No.-

        Christian teaching about the reading the Bible is no mere formal principle of knowledge but rather a piece of practical, spiritual counsel. The way of reading the Bible is closely related to the way of understanding what the nature of the Bible is. Rightly grasping the nature of the Bible involves both rational assent and a pious disposition of mind, will and affection. Such attitudes are to characterise the faithful reader of the Bible, and their absence denotes a degenerate understanding of what is involved in reading it. To set the issue of reading the Bible, this essay first draws a contrast between a representative modern account of what might be termed the 'anthropology of reading' – that of A. Schopenhauer – and that of a reformer J. Calvin. For Schopenhauer, 'reading' totally depends on a way of someone's 'thinking'. So 'thinking' is always prior to 'reading'. However, for Calvin, reading, especially reading the Bible, is not simply human's spontaneous act, but human's response to what she is hearing from what s/he is reading. On the basis of this contrast, we move on to a dogmatic sketch of what it means to read the Bible in the economy of the grace of the triune God. And we reflect critically on the self-centred reading ofthe Bible which has been emerged and appeared among Korean Christians and theological seminaries.

      • KCI등재후보

        갑바도기아 교부들의 삼위일체적 하나님 언어 이해

        정건(Jung, Gun) 개혁신학회 2010 개혁논총 Vol.15 No.-

        In recent times the doctrine of the Trinity has provoked a flood of literature from contemporary theologians. Waves of information concerning relationality, community and identity have washed up on the shores of Christian bookshops. The deluge has had a great deal of success in bringing the doctrine to a high tide of interest and relevance within the daily flow of Christian life. In fact, the Trinity can be said to soak the academic mindset of systematic theologians and to water the congregations they serve. The today's world, however, seeks out the voices of the hitherto unnoticed and suppressed. One of the voices is the feminist challenge. Some feminist theologians have decided that the problems handed down from the beginning of the Christian tradition produced in the patriarchal culture are insoluble. Their premise is that the traditional explication of the Trinity and the Trinitarian God-language has promoted a biased and false linguistic perception of a masculine and, by implication, male Divinity. So, they have concluded that, without change, Christianity is no more compatible with the religious needs and aspirations of women. This strategy is based on the claim that Godlanguages in Scripture are metaphorical. Therefore, for those for whom it is an unhelpful way of describing God, feminists insist that other more helpful metaphors for today should be used in worship and liturgy. There is another way of understanding the language used for God in Scripture. Rather than seeing God-language as a tool which we choose to make sense of God, we understand it as God's gift to us through which God reveals who he is. This means that God-language, particularly theological metaphor in this discussion, is related to God's use of the language in the Word of God through the power of Holy Spirit rather than to our own use of the language in human experience. Language is limited to what is revealed by the particular object to which it refers. This approach to God-language, taken by the Cappadocian Fathers, can be called a 'theological realist' way. If theology matters, Christian worship, liturgy and life also matter. Theology must contribute to make Christian practice a 'theologically-based' action and confession. This aspect is important for the practical theology. In order to be Christian worship, liturgy and life, it must refer to God as Father, Son, and Holy Spirit in our prayers, praises, and baptism as it is written in Scripture. Moreover, it should be argued for the faith and life of the church in this thesis that God is neither male nor female and, simultaneously, that God-language is not gender-originated or gender-specific language. Instead, God is the personal and relational being who is made known to us as the Father, the Son and the Holy Spirit in a way which is beyond gender. This relational God is not only for us but also with us, so that only by participation in His life are we able to share his glorious life without discrimination between male and female and to love one another as He is in himself.

      • KCI등재후보

        에베하르트 융엘(Eberhard Jüngel)의 신학에 있어서 하나님의 계시와 성경의 중심성

        정건(Jung, Gun) 개혁신학회 2009 개혁논총 Vol.11 No.-

        In this article, I'd like to articulate Jüngel's theological method, if we can call it his method, noticing how Jüngel conceives theology and also the practice of theology. In order to clarify Jüngel's view of theological method, I will analyse his distinctive approach, and do so in three parts. In the first part, I will describe Jüngel's three basic hermeneutical decisions, in which the centrality of God's revelation and the Bible to Christian theology is distinctive. In the second part, I will explore Jüngel's theological method in depth. In order to do this, it will be helpful to understand Jüngel's theology, when his three basic hermeneutical decisions are considered in comparison with the views of some contemporary American theologians, David Tracy and Gordon Kaufman, because they have developed their own critical methodologies, which are opposed to Jüngel's theological position on God's revelation and the doctrine of the Bible. In the last part, I will look at his understanding and meaning of 'the authentic evangelical theology'. Through combining an understanding of God's revelation and the Bible in his theological thinking, Jüngel arrives at his distinctive position on the issue of theological method, and his position will give a fruitful foundation for contemporary issues on the reformed theology and studies in the general academic fields.

      • KCI등재

        산-염기 표면처리된 MWNTs의 첨가가 탄소섬유 강화 복합재료의 기계적 계면특성에 미치는 영향

        정건(Gun Jung),나창운(Chang Woon Nah),서민강(Min Kang Seo),변준형(Joon Hyung Byun),이규환(Kyu Hwan Lee),박수진(Soo Jin Park) 한국고분자학회 2012 폴리머 Vol.36 No.5

        본 연구는 표면처리에 따른 탄소나노튜브의 표면특성변화가 탄소섬유 강화 복합재료의 기계적 물성에 미치는 영향에 대하여 살펴보았다. 표면처리된 탄소나노튜브의 표면특성은 산-염기도 측정, FTIR, 그리고 XPS를 통하여 알아보았다. 복합재료의 기계적 계면특성은 층간전단강도(interlaminar shear strength; ILSS)와 임계응력세기인자(critical stress intensity factor; KIC)를 통하여 고찰하였다. 실험결과 산-염기 상호반응에 의한 각각의 표면처리된 탄소나노튜브의 표면특성의 변화를 가져오며, 산처리한 MWNTs/탄소섬유/에폭시 복합재료의 경우 미처리 MWNTs, 염기 처리 MWNTs와 비교하여 우수한 기계적 물성을 보였다. 이는 산성을 가지는 MWNTs와 염기성의 에폭시 수지가 산-염기 및 수소결합에 의한 계면 결합력의 향상 때문이라 판단된다. In this work, the effect of chemical treatments of multi-walled carbon nanotubes (MWNTs) on the mechanical interfacial properties of carbon fiber fabric-reinforced composites was investigated. The surface properties of the MWNTs were determined by acid and base values, Fourier transform infrared spectroscopy (FTIR), and X-ray photoelectron spectroscopy (XPS) analyses. The mechanical interfacial properties of the composites were assessed by interlaminar shear stress (ILSS) and critical stress intensity factor (KIC). The chemical treatments based on acid and base reactions led to a significant change of surface characteristics of the MWNTs, especially A-MWNTs/carbon fibers/epoxy composites had higher mechanical properties than those of B-MWNTs and non-treated MWNTs/carbon fibers/epoxy composites. These results were probably due to the improvement of interfacial bonding strength, resulting from the acid-base interaction and hydrogen bonding between the epoxy resins and the MWNT fillers.

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