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장성원,조윤구,김주원,길제령,김미영,이영 대한영상의학회 2018 대한영상의학회지 Vol.79 No.5
Purpose: To evaluate the effect of portal hypertension on the tumor recurrence in patients with hepatocellular carcinoma (HCC) and without hepatic decompression following radiofrequency ablation (RFA). Materials and Methods: Treatment-naïve HCC patients within the Milan criteria and with Child-Pugh class A were included in this study, who had performed RFA in our hospital between January 2010 and March 2017. Univariate and multivariate analyses using the Cox proportional hazard model were performed to find the predictors of local or distant tumor recurrence. Results: Overall, 178 patients were included in this study. Median follow-up period was 40.2 months. The difference in the local tumor progression rates depending on the absence or presence of portal hypertension was not statistically significant (p = 0.195). The 1-, 3-, and 5-year distant intrahepatic tumor spread rates were 6.6%, 29.5%, and 537% in patients without portal hypertension, and 23.4%, 51.9%, and 63.6% in patients with portal hypertension, respectively. The difference was statistically significant (p = 0.011). Univariate and multivariate analysis showed that portal hypertension was an independent predictor for distant intrahepatic tumor spread (p = 0.008). Conclusion: For HCC patients with Child-Pugh class A, portal hypertension adversely affected distant intrahepatic tumor progression.
기술 융합형 웹툰 이용자의 이용의도에 영향을 미치는 요인들에 대한 연구
장성원,성동규 한국콘텐츠학회 2020 한국콘텐츠학회논문지 Vol.20 No.2
This research was trying to examine through the technology acceptance model that is expanded in order to make an inquiry the factors having an effect on the acceptance intention of the technology fusion type webtoon user. The survey was carried out for the research for 114 questionnaire respondents where there is the technology fusion type webtoon utilization experience. After and hierarchical regression analysis was performed and the relationship was analyze between the factor. The total 13 hypotheses and one research problems were set and the study with was proceeded. Next, it is same if the results of study is summarized. Firstly, the interactivity and immersion, that is the subordinate factor of the Siljaegam, affected the static influence to the perceived usability. Secondly, with having the static influence an effect on the technology fusion type webtoon use intention the perceived usability was confirmed. Thirdly, the effeciency, Tendency of Conciseness, and consistency were the technology fusion type GUI standard extracted with the Ttamsaekjeok the result subfactor that it analize factor. Finally, with giving the meaningful influence to the perceived easiness the visual unrefined copper steam, that is the subordinate factor of the Siljaegam, was confirmed. 본 연구는 기술 융합형 웹툰 이용자의 수용의도에 영향을 미치는 요인들을 알아보기 위해 확장된 기술수용모델을 통해 살펴보고자 하였다. 연구를 위해 기술 융합형 웹툰 이용 경험이 있는 설문 응답자 114명을 대상으로 설문조사를 실시하였다. 이후, 위계적 회귀분석을 실시하여 변인 간 관계를 분석하였다. 총 13개의 가설, 1개의 연구문제를 설정하여 연구를 진행하였다. 연구 결과를 요약하면 다음과 같다. 첫째, 실재감의 하위 요인인 상호작용성, 몰입은 인지된 유용성에 정적인 영향을 미쳤다. 둘째, 인지된 유용성은 기술 융합형 웹툰 이용의도에 정적 영향을 미치는 것으로 확인되었다. 셋째, 기술 융합형 GUI 척도를 탐색적 요인분석한 결과 하위요인으로 효율성, 간결성, 일관성이 추출되었다. 마지막으로 실재감의 하위 요인인 시각적 생동김은 인지된 용이성에 유의미한 영향을 주는 것으로 확인되었다. 이 같은 연구 결과는 기존의 멀티미디어 기술적 요소만을 검증하는 연구가 아닌, 인간의 감정이나 심리적 요인을 통해 기술 융합형 웹툰의 이용의도에 영향을 미치는 변수를 파악하였다는 점에서 학술적 의의를 찾을 수 있다.
장성원,승기배,박훈준,박찬석,김동빈,김승훈,김범준,정해억,백상홍,최규보 대한심장학회 2008 Korean Circulation Journal Vol.38 No.1
Background and Objectives: The presence of elevated troponin after percutaneous coronary intervention (PCI) is considered to reflect irreversible myocardial injury. However, its prognostic value remains unclear. The purpose of this study was to investigate the incidence, risk factors, and clinical outcomes of troponin I (TnI) elevation after the implantation of drug-eluting stent (DES). Subjects and Methods: We performed a retrospective analysis of 335 patients who had undergone PCI with DES. Patients who had acute coronary syndrome with elevated TnI levels before PCI were excluded. TnI levels were measured 6 and 24 hours after PCI. Results: Baseline clinical characteristics were similar in the elevated TnI and normal TnI groups. Elevated postprocedural TnI (>1.5 ng/mL) occurred in 52 patients (15.5%). Univariate analysis revealed that the clinically significant variables were multi-vessel disease (p<0.001), multiple stent implantation (p=0.003), total stent length (p=0.001), side-branch occlusion (p<0.001), and bifurcation lesion (p=0.003). Multivariate analysis indicated that the independent predictors of elevated TnI after DES implantation were multi-vessel disease (p=0.019), side-branch occlusion (p=0.001), and bifurcation (p=0.011). There were no significant differences in major adverse cardiovascular events between the elevated TnI and normal TnI groups (p=0.461). Conclusion: Multi-vessel disease, side-branch occlusion, and bifurcation were independent predictors of elevated TnI following DES implantation. The elevation of TnI after successful PCI with DES was not associated with worse 400-day clinical outcomes. (Korean Circ J 2008;38:12-16)