화학적인 용액 코팅방법에 의한 박막형 고온초전도체에 사용되는 SUS310 금속모재의 평탄화 연구

이종범,이현준,김병주,권병국,김선진,이종수,이철영,문승현,이희균,홍계원,Lee, J.B.,Lee, H.J.,Kim, B.J.,Kwon, B.K.,Kim, S.J.,Lee, J.S.,Lee, C.Y.,Moon, S.H.,Lee, H.G.,Hong, G.W. 한국초전도학회 2011 Progress in superconductivity Vol.12 No.2

The properties of $2^{nd}$ generation high temperature superconducting wire, coated conductor strongly depend on the quality of superconducting oxide layer and property of metal substrate is one of the most important factors affecting the quality of coated conductor. Good mechanical and chemical stability at high temperature are required to maintain the initial integrity during the various process steps required to deposit several layers consisting coated conductor. And substrate need to be nonmagnetic to reduce magnetization loss for ac application. Hastelloy and stainless steel are the most suitable alloys for metal substrate. One of the obstacles in using stainless steel as substrate for coated conductor is its difficulties in making smooth surface inevitable for depositing good IBAD layer. Conventional method involves several steps such as electro polishing, deposition of $Al_2O_3$ and $Y_2O_3$ before IBAD process. Chemical solution deposition method can simplify those steps into one step process having uniformity in large area. In this research, we tried to improve the surface roughness of stainless steel(SUS310). The precursor coating solution was synthesized by using yttrium complex. The viscosity of coating solution and heat treatment condition were optimized for smooth surface. A smooth amorphous $Y_2O_3$ thin film suitable for IBAD process was coated on SUS310 tape. The surface roughness was improved from 40nm to 1.8 nm by 4 coatings. The IBAD-MgO layer deposited on prepared substrate showed good in plane alignment(${\Delta}{\phi}$) of $6.2^{\circ}$.

Mechanism of Inhibitory Effect of Imipramine on Isolated Rat Detrusor Muscle in Relation to Calcium Modulation

이종범,유계준,하정희,권오철,이광윤,김원준,Lee, Jong-Bum,Yoo, Kae-Joon,Ha, Jeoung-Hee,Kwon, Oh-Cheol,Lee, Kwang-Youn,Kim, Won-Joon The Korean Society of Pharmacology 1992 대한약리학잡지 Vol.28 No.1

항우울제에 속하는 imipramine은 유뇨증에 대한 치료제로서도 널리 사용되고 있다. Imipramine이 유뇨증 치료제로서의 명백한 치료효과를 보이기는 하나, 그 작용기전에 대해서는 아직 논란이 많다. 그 중 가장 유력한 설은 말초성 자율신경에 대한 작용으로서 무스카린성 길항작용과 교감신경말단에서의 catecholamine 재섭취 방해작용 및 직접적인 방광근 이완 작용 등이 제시되고 있다. 또 최근에는 방광 평활근에 대한 직접작용에 칼슘 이동 억압 작용이 중요한 역할을 한다고 주장되고 있다. 이에 본 실험에서는 흰쥐의 적출방광 배뇨근 절편을 사용하여 imipramine의 항유뇨작용과 calcium동원과의 관련성을 추구하여 다음과 같은 결과를 얻었다. 1. 배뇨근 절편은 전기장자극에 의해 주파수의존적으로 수축하였는데, 이 전기장자극 유발 수축반응은 imipramine에 의해 농도 의존적으로 억제되었고 고농도에서는 완전히 소실되었으나, atropine에 의해서는 고농도에서도 소실되지 않았다. 2. Imipramine은 자발수축 및 기본 장력에 대하여 이들을 농도 의존적인 양상으로 억제하였으며, 이 억제작용은 diltiazem에 의한 억제와 유사하였다. 그러나 atropine은 배뇨근절편의 기본장력이나 자발수축에 아무런 영향도 미치지 않았다. 3. $^*Imipramine$은 bethanechol 유발수축과 adenosine triphosphate (ATP) 유발수축을 농도의존적으로 억압하였다. 4. Imipramine은 칼슘배제용액에서 칼슘 첨가에의한 수축성의 회복을 억제하였는데, 이러한 작용은 diltiazem보다 그 효력이 낮았으나 그 작용양상은 유사하였다. 5. Imipramine에 의해 감소되었던 배뇨근절편의 기본장력은 calcium ionophore인 A23187에 의해 회복되었다. 칼슘배제 영양액에 장시간 노출됨으로써 기본장력은 소실되었으며, imipramine을 전처치한 경우는 A23187첨가에 의해 장력이 회복되지 않았으나, 세포내칼슘 유리억제제인 trimethoxybenzoic acid 8-(diethylamino)octyl ester [TMB-8]을 전처치한 경우 A23187은 배뇨근의 기본장력을 현저히 회복시켰다. 이상의 결과로 미루어 보아 imipramine의 배뇨근 수축 억제작용의 기전에는 무스카린성 및 퓨린성 수용체봉쇄작용도 관여하나, 주된 기전은 평활근세포에 직접 작용하여 세포외 칼슘의 유입을 억제하는 것으로 사료된다. Enuresis is a common voiding disorder among children. There are several therapeutic regimens for the disorder available today; behavioral therapies, psychotherapy, bladder training, sleep interruption, hypnosis and drug therapy. Recently, the efficacy of drug therapy has been acknowledged, particularly of antidepressants. Among the tricyclic antidepressants, imipramine is most frequently employed for the treatment of enuresis. Present study was undertaken to investigate the mechanism of imipramine on the contractility of urinary bladder in relation to the calcium modulation using isolated strips of rat detrusor urinae. 1. The electric fileld stimulation-induced contraction was abolished by imipramine, but partially inhibited by atropine. 2. Imipramine reduced the basal tone and diminished the phasic activity of detrusor muscle concentration-dependently, which was similar to that of diltiazem, a calcium channel blocker. 3. Imipramine suppressed the maximal responses and shifted the concentration-response curves of bethanechol and ATP to right. 4. Imipramine inhibited the calcium-induced recovery of tension in calcium-free physiologic salt solution (PSS) with a mode of action similar to that of diltizaem. 5. A23187, a calcium ionophore recovered the basal tone which had been reduced by imipramine in normal PSS. 6. In calcium-free PSS, A23187 could recover the abolished basal tone with the pretreatment of imipramine, but it exerted a partial recovery with the pretreatment of TMB-8, an inhibitor of intracellular calcium release. Based on these results, it is suggested that the inhibitory action of imipramine on the detrusor muscle exerted in part by blockade of the muscarinic and purinergic receptors, and interference with the influx of extracellular calcium, but not with the release of intracellular stored calcium, is involved in its mechanism of action.

신생대 3기 퇴적이암지역에서의 사면 밑 교량설계사례

이종범,김창현,김경태,한진희,이광희,Lee, Jong-Beom,Kim, Chang-Hyeon,Kim, Gyeong-Tae,Han, Jin-Hui,Lee, Gwang-Hui 한국지반공학회 2007 지반 : 한국지반공학회지 Vol.23 No.2

Safe와 Non-safe 전력 부하 라인 분석을 위한 TFP트리 기반의 점진적 출현패턴 마이닝

이종범,박명호,류근호,Lee, Jong-Bum,Piao, Ming Hao,Ryu, Keun-Ho 한국공간정보학회 2011 한국공간정보학회지 Vol.19 No.2

본 논문에서는 특정 지역의 전력 소비 데이터를 이용하여 safe와 non-safe 전력 부하 라인의 차이를 분석하여 정의하고, 출현패턴을 사용하여 잠재되어 있는 non-safe라인을 식별하기 위하여 제한된 메모리에서 효율적으로 패턴을 찾을 수 있는 TFP-tree 기반의 점진적 출현패턴 마이닝 알고리즘을 제안한다. 특히, 두 개의 다른 최소 지지도 값을 사용하여 전력 소비 데이터와 같은 대용량 데이터에서의 마이닝 문제를 해결한다. In this paper, for using emerging patterns to define and analyze the significant difference of safe and non-safe power load lines, and identify which line is potentially non-safe, we proposed an incremental TFP-tree algorithm for mining emerging patterns that can search efficiently within limitation of memory. Especially, the concept of pre-infrequent patterns pruning and use of two different minimum supports, made the algorithm possible to mine most emerging patterns and handle the problem of mining from incrementally increased, large size of data sets such as power consumption data.

자동차 전장부품의 초 가속 실뇌성 수명시험 방법에 관한 연구

이종범,조재립,Lee, Jong-Beom,Cho, Jai-Rip 한국품질경영학회 2000 품질경영학회지 Vol.28 No.4

Recently days, High Accelerated Life Test of electrical and electronic parts is increasing its importance. This study set the hypothesis to develop the method that was analysis and application of HALT for the automotive electrical and electronic parts, it used Arrhenius's Model and Eyring's Model, and ESS theory. Validity of application is proved by other test data. Especially, this study emphasis on utility of acceleration to temperature, humidity, voltage, mechanical stress and other stress. In this study set the pattem of practical application. Therefore, this study emphasis on the application of the HALT and the use of other parameter by acceleration reliability test data. The result of this study is as follows. 1) There is relationship between molar weight and material constant. 2) Characteristic of material is operating acceleration factor as well as parts failure factors. Of course, according to the characteristic of material, activation energy is often more important than molar weight. But it will be defined by more testing and improvements in practical application.

열병합발전시스템 운용의 국내외 현황과 전망 및 과제

이종범,Lee, Jong-Beom 한국전기산업진흥회 1993 電氣産業 Vol.4 No.2

전자빔 증발법에 의한 박막형 고온초전도체의 $CeO_2$ 버퍼층 증착 연구

이종범,박신근,김혜진,문승현,이희균,홍계원,Lee, J.B.,Park, S.K.,Kim, H.J.,Moon, S.H.,Lee, H.G.,Hong, G.W. 한국초전도학회 2010 Progress in superconductivity Vol.11 No.2

The properties of buffer layer for thermal and chemical stability in coated conductor is a very important issue. $CeO_2$ has desirable thermal and chemical stability as well as good lattice match. In this study, $CeO_2$ was deposited by electron beam deposition. The MgO(001) single crystal and LMO buffered IBAD substrate(LMO/IBAD-MgO/$Y_2O_3/Al_2O_3$/Hastelloy) were used as substrates, which have $\Delta\phi$ values of ${\sim}8.9^{\circ}$. The epitaxial $CeO_2$ films was deposited with high deposition rate of $12{\sim}16\;{\AA}/sec$. During deposition, the change of oxygen partial pressure(${\rho}O_2$) does not cause change in c-axis texture. In case of $CeO_2$ on MgO single crystal, the substrate temperature was optimized at $750^{\circ}C$ with superior $\Delta\phi$ and $\Delta\omega$ value. Otherwise, In case of LMO buffered IBAD substrate, It was optimized at $650^{\circ}C$ with increasing its deposition thickness of $CeO_2$, which was finally obtained with best $\Delta\phi$ value of $5.5^{\circ}$, $\Delta\omega$ value of $2^{\circ}$ and Ra value of 2.2 nm.

건강상담실

이종범,Lee Jong-Bum 한국건강관리협회 1990 건강소식 Vol.14 No.3

肛腸療法에 의한 辛蒲湯의 抗아나필락시 效果

이종범,문석재,문구,원진희,김태균,배남규,Lee, Jong-Beom,Mun, Seok-Jae,Mun, Gu,Won, Jin-Hui,Kim, Tae-Gyun,Bae, Nam-Gyu 대한한방안이비인후피부과학회 2001 한방안이비인후피부과학회지 Vol.14 No.1

Objective : Anal Therapy is another way of taking medicine and applies to each field of clinical treatment extensively. Sinpo-tang(SPT) has been used for the treatment of a allergic rhinitis. In this study, the auther investigated the anti anaphylactic action of Sinpo-tang by anal therapy was investigated on cutaneous allergic reaction models. Methods : Results : 1. Sinpo-tang (0,001-0.1 g/kg) dose-dependently inhibited the compound 48/80-induced ear swelling response in mice. Inhibitory effect of Sinpo-tang was significant (P < 0.05) at the doses of 0.01, 0.1 g/kg. 2. Sinpo-tang (0.001-0.1 g/kg) inhibited the cutaneous allergic reaction activated by anti-dinitrophenyl IgE in rats. Of special note, Sinpo-tang (0.1 g/kg) inhibited the cutaneous allergic reaction by $68\%$. 3. This inhibitory effect of Sinpo-tang was confirmed by observation of alcian blue/nuclear fast red stained-mast cells in the cutaneous tissue. 4. Sinpo-tang (0.01-1 g/L) dose-dependently inhibited the compound 48/80-induced histamine release from the peritoneal mast cells. Conclusions :These results indicate that anal therapy of Sinpo-tang may be beneficial in the treatment of mast cell-mediated anaphylaxis by inhibition of histamine release from mast cells in vivo and in vitro.

행정학과 교육프로그램 개발에 관한 연구

이종범,김준한,정용덕 ( Chong - Bum Lee,Joon - Han Kim,Yong - Duck Jung ) 한국행정학회 1990 韓國行政學報 Vol.24 No.1