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이은실,이영주,김지현,전순실,Lee, Eun-Sil,Lee, Young-Ju,Kim, Ji-Hyun,Chun, Soon-Sil 한국식품영양학회 2020 韓國食品營養學會誌 Vol.33 No.2
This purpose of this study was to investigate the quality characteristics of jellies added with lemon myrtle extract. Lemon myrtle leaves were extracted for 0, 3, 5, 7, 9 minutes, respectively, in 90℃ water and used for jelly preparation. The moisture content of control showed the lowest value and the content increased significantly as the extraction time of lemon myrtle increased. The pH of L0 was significantly high and increased significantly with the increase of extraction duration time. The lightness value was the lowest in the L3. The redness showed the lowest value in the L9. The yellowness showed the lowest value in the L0. In texture properties the hardness of L9 showed the highest value and the lemon myrtle extraction duration increased significantly. The cohesiveness was highest in the L0 and lowest in the L5. Gumminess and chewiness increased significantly with increasing extraction duration. Total polyphenol content was the highest in the L5 and the jellies with lemon myrtle extracts were significantly higher than the L0. DPPH radical scavenging activities increased significantly with increasing extraction duration. The ABTS radical scavenging activity of the L0 was the lowest. In the sensory evaluation overall preference, color, sweetness, texture, and lemon myrtle flavor did not show any significant differences among the samples.
이은실,최광해,Lee, Eun Sil,Choi, Kwang Hae 대한소아감염학회 1997 Pediatric Infection and Vaccine Vol.4 No.2
Purpose: To prevent residual physical disability and chronic infection, prompt diagnosis and adequate treatment are important in the skeletal infections in children. Although radioisotope scanning is knwon as the method of choice for early diagnosis of bone infection, we conducted a study on twenty nine children who had skeletal infections to reevaluate the most appropriate way in diagnosis and management. Methods: A retrospective study was conducted on twenty nine children, who were admitted to the departments of Pediatrics and Orthopedic Surgery and who had acute osteomyelitis or septic arthritis, through review of medical records, radiologic & radioisotope study results. Their diagnoses were confirmed by bacteriologic cultures on the aspirated specimens from suspected bony lesions. Results: 1) Among twenty nine patients, there were 6 infants including 5 newborn infants, and 23 children were aged between 1 and 15 years. Male to female ratio was 1.4 to 1. 2) Point tenderness was noted in all cases, and the common physical signs were swelling, limitation of motion, fever and local heat in the order of frequency. 3) Fifty two percents of the patients were diagnosed within a week after onset of symptoms and all cases were within 15 days. 4) Leukocytosis was noted in only 58.6% of cases but erythrocyte sedimentation rate was increased in all cases except only one case. Staphylococcus aureus was revealed as the most common etiologic agent. 5) Radioisotope scans showed hot uptake in five of six cases(83.3%) who had no abnormal finding on plain skeletal radiolograms. Conclusions: Although radioisotope scan and MRI are helpful in early diagnosis before radiologic finding was detected on plain X-ray film, the antimicrobial therapy can be started after bacteriologic study of the aspirated specimens from the suspected skeletal lesions if skeletal infection is highly suspected clinically.
젖소 유방염으로부터 분리한 그람음성균의 분포 및 항생제 감수성
이은실,강현미,정충일,문진산,Lee, Eun-Sil,Kang, Hyun-Mi,Chung, Chung-il,Moon, Jin-San 대한수의학회 2007 대한수의학회지 Vol.47 No.1
Environmental mastitis has increased particularly in well-managed or low somatic cell countherds that have successfully controled contagious pathogens. Major pathogens of environmental mastitisare Escherichia coli (E. coli) and Streptococcus uberis. The present study was conducted to investigate1,865 quaters of 241 Korean dairy farms from 2001 to 2004. Prevalence of major gram-negative bacteriaisolated from mastitis milk were E. coli (22.7%) and Enterobacter spp. (16.3%) in coliforms and Pseudomoassp. (10.3%) and Serratia spp. (7.9%) in non-coliforms. The results on antibiotic susceptibility by agardifusion test against these pathogens were 86.7% in piperaciliin, 94.6% in cefepime, 85.5% in amikacin,87.7% in gentamicin and so on. In contrast, the susceptibility against ampicillin (41.9%), cephalothin (9.9%),streptomycin (39.9%) and tetracycline (46.7%) appeared to be below 50%. Gram-negative bacteria showed(96.8%). Acording to year, distribution of high $256{\sim}64{\mu}g/ml$ on cephalothin get increased, but the othersare diferent. These findings demonstrate that major gram-negative bacteria were E. coli and Enterobacterspp. isolates, and often encountered the diverse antibiotic resistant patterns.
체외수정시술 환자의 과배란유도시 저용량 아스피린 투여의 효용성에 관한 연구
이은실,이상훈,Lee, Eun-Sil,Lee, Sang-Hoon 대한생식의학회 2001 Clinical and Experimental Reproductive Medicine Vol.28 No.3
Objective : To evaluate the efficacy of low-dose aspirin on IVF outcome and endometrium in patients undergoing IVF-ET. Materials and Methods : From February, 2001 to Jun, 2001, 60 infertile patients were randomly divided into study group (28 cycles) and control group (32 cycles). The study group received a daily oral dose of 25 mg of aspirin for at least 2 weeks from first visiting day. Controlled ovarian hyperstimulation was initiated in all patients with the GnRH agonist starting in the midluteal phase of the previous cycle. Results: There were no significant differences in age of the patients, basal serum E2, LH, FSH level and endometrial thickness among two groups. There were no statistically significant differences between the study group and the control group respectively in dosage ($26.5{\pm}4.8$ vs $26.2{\pm}5.3$ amples) and duration ($10.4{\pm}4.2$ vs $9.8{\pm}5.3$ days) of gonadotropin administration, serum E2 level on the hCG administration day ($1823{\pm}342$ vs $1854{\pm}543$), LH ($14.5{\pm}2.7$ vs $14.8{\pm}3.1$), FSH ($16.7{\pm}3.4$ vs $18.3{\pm}4.7$), the number of follicles > 15 mm ($13.2{\pm}6.3$ vs $12.8{\pm}5.9$), the number of oocytes retrieved ($9.2{\pm}2.4$ vs $8.4{\pm}1.7$), the number of embryos transferred ($4.7{\pm}2.0$ vs $4.7{\pm}2.0$), fertilization rate (68.4% vs 64.5%), implantation rate (21.3% vs 17.6%), and clinical pregnancy rate (28.4% vs 26.2%). The endometrial thickness and the percentage of endometrial trilaminar pattern on hCG day were significantly higher in study group than control group ($12.9{\pm}3.7mm$ vs $10.4{\pm}2.8mm$, 78.3% vs 64.5%). Conclusion: Many reports suggest that low-dose aspirin improve ovarian response, implantation rate, fertilization rate, implantation rate, and pregnancy rate by increasing the blood flow, but we couldn't prove the significant effect of low-dose aspirin on the IVF outcome except on endometrium. This may be affected by dose of aspirin, duration, and number of patients studied. This trial is small, so our results highlight the need for a large randomized controlled trial to identify the effect of low-dose as pirin on IVF-ET outcome.
30대 국내여성의 손톱 사이즈 측정을 통한 네일 팁 사이즈 제안
이은실(Eun-Sil Lee), 김은실(Eun-Sil Kim) 한국인체미용예술학회 2020 한국인체미용예술학회지 Vol.21 No.3
In recent years, the global economy has been shifting from manufacturing to service, and especially in the beauty industry, interest is increasing in the nail industry as well as in the theoretical field. With the introduction of nail art in Korea, it entered the mid-2000s, and even the self-nail group appeared. In addition, as the demand for online shopping malls and offline shopping malls surges, more and more consumers enjoy self-nailing. In addition, as it was revitalized around women in their 20s and 30s, looking at the tendency of domestic women in their 30s, the highest proportion of consumers who thought they were the consumer was the highest. In the meantime, the previous study suggests measurements of fingernail size and tip size, but the results of the previous study have only performed direct measurement. Therefore, in this study, direct measurement and 3D scanner measurement were measured for women in their 30s among domestic women. The purpose of this study is to compare and analyze the nail size of 30 nails, and then to suggest the size of the nail tip. In addition, it is of great significance that the measurement was attempted using a 3D scanner measurement method.
이반드로네이트 주사제의 6개월 및 12개월 지속성 -예비 연구부분-
이은실 ( Eun Sil Lee ),서석교 ( Seok Kyo Seo ),이병석 ( Byung Seok Lee ),박형무 ( Hyoung Moo Park ) 대한폐경학회 2009 대한폐경학회지 Vol.15 No.2
Objectives: This study was to evaluate persistence of quarterly intravenous injection of ibandronate and factors relative to persistence. Methods: In this retrospective study, 136 postmenopausal women with osteopenia or osteoporosis who received injections of ibandronate between August 2007 and October 2008 were evaluated for persistence to intravenous ibandronate, reasons for their choice of ibandronate, reasons for stopping medication, acute inflammatory reaction, and other medications after stopping ibandronate by chart review, questionnaire, and telephone interview. Results: Persistence at 6 months and 12 months was 88.1% and 82.8%, respectively. Patients chose ibandronate for reasons of convenience of a quarterly injection, GI trouble, and the inconvenience of oral bisphosphonates, and other medications. Reasons for stopping ibandronate included adverse effects, inconvenience of a direct visit to the hospital at quarterly intervals, cost, and so on. Acute inflammatory reactions were more noticeable in the non-persistent group than in the persistent group, and a previous history of oral bisphosphonate did not affect occurrence of acute inflammatory reactions. Conclusion: Intravenous ibandronate is a good alternative to oral osteoporosis medications due to the convenience for quarterly injection and no GI trouble, and may increase persistence of osteoporosis medication.
Gail Model을 이용한 한국여성의 유방암 위험도 측정
이은실 ( Eun Sil Lee ),박형무 ( Hyoung Moo Park ),홍연표 ( Yeon Pyo Hong ),서재승 ( Jae Seung Seo ) 대한폐경학회 2012 대한폐경학회지 Vol.18 No.3
Objectives: The aim of this study is to estimate the relative risk for breast cancer using the Gail model and to observe the relationship between mammographic density and the 5-year risk of breast cancer. Methods: A total of 600 women who visited the Department of Obstetrics and Gynecology in Chung-Ang University Yongsan Hospital were screened using the Gail model to estimate their relative risk for breast cancer. The correlation between the 5-year risk of breast cancer and the mammographic density of 462 women who had performed mammography within 1 year of the study was analyzed. Results: The mean age of the study subjects was 56.7 ± 8.2 years. The estimated mean values for the 5-year risk and lifetime risk for breast cancer were 1.23 ± 0.46% and 7.90 ± 2.76% respectively in all study subjects. The estimated mean value of the 5-year risk for breast cancer increased with age. Otherwise, the estimated lifetime risk for breast cancer decreased with age. Ninety-two women (15.3%) were classified as high-risk because their estimated 5-year risk was over 1.67% or their lifetime risk was over 20%. High risk percentages according to age were 10.5% in the thirties, 0.84% in the forties, 7.2% in the fifties, 32.7% in the sixties, and 35.7% in the seventies. Among the high risk postmenopausal women, 52.2% were taking hormone therapy. Mammographic density was not significantly correlated with the estimated 5-year risk for breast cancer. Conclusion: About fifteen percent of study subjects were at high risk for breast cancer according to the estimated 5-year risk or lifetime risk for breast cancer using Gail model. Mammographic density was not correlated with the 5-year risk for breast cancer. (J Korean Soc Menopause 2012;18:180-186)