소아 만성 신부전 환자에서 발생한 위혈관 이형성증의 Hemoclipping에 의한 지혈 치료 1례

이윤진,김영미,김수영,박재홍,Lee, Yun-Jin,Kim, Young-Mi,Kim, Su-Young,Park, Jae-Hong 대한소아소화기영양학회 2003 Pediatric gastroenterology, hepatology & nutrition Vol.6 No.2

Angiodysplasia is the most common vascular abnormality of the gastrointestinal tract and probably the most frequent cause of recurrent lower intestinal bleeding in otherwise healthy elderly patients. Also, it is an important cause of hemorrhage in chronic renal failure observed in up to 19~32% of patients. Bleeding due to gastric angiodysplasia is treated by various endoscopic approaches, including argon and Nd : YAG laser photocoagulation, monopolar or bipolar electrocoagulation, heater probe, injection sclerotherapy, band ligation or hemoclipping. A 15-year-old boy, who had undergone hemodialysis for chronic renal failure for about 10 years, was admitted due to melena and progressive anemia. A gastroduodenoscopy revealed a cherry red and fern-like lesion with oozing on the posterior wall at junction of gastric body and fundus. Endoscopic hemoclipping therapy was performed. However, melena recurred four days later. Argon plasma coagulation and hemoclipping therapy were performed again. Since then, no recurrence of bleeding has been observed.

Glutary 7-Aminodeacetoxycephalosporanis Acid Acylase 생산균의 분리 및 동정

이윤진,임재윤,Lee, Yun-Jin,Lim, Jai-Yun 한국미생물학회 1994 미생물학회지 Vol.32 No.3

Glutaryl 7-aminodeacetoxycephalosporanic acid(GL-7-ADCA)로부터 7-aminodeacetoxycephalosporanic acid(7-ADCA)를 생성하는 GL-7-ADCA acylase생산균을 자연계에서 폭넓게 검색하여 한균주를 선정하고 분리균의 형태 및 생리적 성질들을 조사하여 Alcaligenes sp.로 동정하였다. 분리균의 효소생산을 위한 배양조건을 검토한 결과 탄소원으로는 glucose, 질소원으로는 yeast extract, monosodium L-glutamate가 우수하였다. 효소의 작용최적 pH는 8.0이며, pH7.0~pH11.0 번위에서 비교적 안정하였다. 5l jar fermentor에서 배양경과를 조사한 결과 효소이 활성은 $37^{\circ}C$, 교반속도 300rpm, 통기량 1vvm 조건에서 20시간~30시간 배양시 가장 높았다. Microorganism producing glutaryl 7-aminodeacetoxycephalosporanic acid (GL-7-ADCA) acylase was screened from soil. The microorganism was identified as Alcaligenes sp. J-421 by its morphology and biochemical properties. Cultural conditions of Alcaligenes sp. J-421 were investigated for the production of GL-7-ADCA acylase. Optimum medium composition was 1% glucose, 1% beef extract, 0.5% yeast extract, 0.2% monosodium L-glutamate, 0.1% glutaric acid, 0.2% NaCl, 0.5% $K_2$ $HPO_4$, and 0.05% $CuSO _4{\cdot}5H_2O$. Optimum cultivation conditions for the production of the enzyme in 5 l jar fermentor were $37^{\circ}C$, tip speed 300 rpm, aeration 1 vvm. Optimum reaction pH of the enzyme was 8.0 and the enzyme was stable at pH7.0-11.0.

일제 식민지 시기 서구 유아교육학 수용 주체와 성격 -아동심리학을 중심으로-

이윤진 ( Yun Jin Lee ) 한국교육사학회 2007 한국교육사학 Vol.29 No.2

이 글은 서구 유아교육학의 여러 영역 중에서 당시 실제 가르치고 배웠던 아동심리학을 중심으로 이 학문의 도입 시기·주체·목적·성격에 대해 분석한 논문이다. 아동심리학은 1918년 이후 기독교계 인사였던 홍병선에 의해 소개되기 시작했고 이후에도 기독교 인사들에 의해 전파되었다. 아동심리학이 적극 활용되었던 공간도 교회주일학교, 보육학교, 유치원 등 기독교계 학교나 관련된 장소였다. 기독교에서 아동심리학을 적극적으로 도입한 이유는 아동의 특성을 잘 파악해서 이에 맞는 종교교육을 실시, 신실한 신자를 양성하기 위해서였다. 또한, 아동심리학은 아동에게 최대한 자유를 허용하는 방임주의 교육을 주장했으며, 문자교육가 아닌 유희(놀이)에 교육적 가치를 부여하는 등 진보적인 학문이었다. 한편, 우리에게는 다소 생소하지만 공산주의 계열의 유아교육학이 존재했었는데, 이 계열의 유아 교육학은 유아에게 단순히 뛰어노는 ``유희``가 아니라 유희가 접목된 ``노동``을 가르쳐야 한다고 주장했다. 그러나 공산주의 계열의 유아교육학은 우리사회의 지배통치이념과 맞지 않아 학문유통과정에서 배제되었다. 오늘날 우리 유아교육학의 주류는 일제 식민지 시기 기독교계에서 적극적으로 수용한 유아교육학이며, 이 학문의 아동관이나 교육방법 면에서는 전통 사회와는 질적으로 다른 ``진보적인`` 학문이었지만, 한편으로는 자본주의 체제 이념에 궁극적으로 부합되는 ``보수적인`` 성격을 동시에 지녔다고 볼 수 있다. This paper deals with the early childhood education taken in Colonial Korea, especially focusing on the establishment of child psychology as field of study. Child psychology was mainly taken and developed by the Christians. The Christians actively applied child psychology in their educational activities such as Sunday School, kindergarten, kindergarten teacher training schools, etc. for successful religious education of children. Child psychology consisted of progressive educational theories which called for maximum freedom of children and placed high values on children`s play. Compared to the characteristic of the communist education for children the foci of the education in the Christian sector were different, especially in the way they deal with play. The communist conception of play was connected with work, not simply playing. Work was the core in communist education. This difference not only affected the particular characteristics of early childhood education that developed during the colonial period but also the ethos of early childhood education after independence. Since the majority of those who had early childhood education during the colonization were Christians, the child psychology which developed after the liberation could easily reject the communist conceptions which were incompatible with the ideology of the South Korean government, i.e., capitalism. Early childhood education during the colonial period, by differentiating with communist conceptions, eventually contributed to developing a theory of early childhood education more susceptible to capitalism.

택사탕의 항산화와 혈중지질에 대한 효과

이윤진 ( Yun-jin Lee ),이은별 ( Eun-byeol Lee ),김현지 ( Hyeon-ji Kim ),양두화 ( Doo-hwa Yang ),김영준 ( Young-jun Kim ),안희덕 ( Hee-duk An ) 한방재활의학과학회 2021 한방재활의학과학회지 Vol.31 No.2

Objectives We evaluated the improving effects of Taeksa-tang (TST) using 3T3-L1 cells and C57BL/6 mice were fed on a high-fat diet. Methods The anti-radical activities of TST were studied using 2,2-diphenyl-1-picrylhydrazyl and 2,2'-azino-bis (3-ethylbenzothiazoline-6-sulphonic acid). The content of total polyphenol was measured using Folin-Ciocalteu reagent, whereas aluminum chloride colorimetric method was used for the content of total flavonoid. Moreover, the factors related to lipid profile and the protein expressions such as β-oxidation and anti-oxidant enzyme were analyzed using serum and western blotting of 3T3-L1 cells. Additionally, we examined lipolysis through glycerol appearance in mouse adipose tissue. Results TST treatment showed strong free radical scavenging activities with half maximal inhibitory concentration and the presence of a amount of total polyphenol and total flavonoid. TST treatment significantly increased factors related to β-oxidation such as carnitine palmitoyl transferase-1 and uncoupling protein 2 via the phosphorlyation of liver kinase B1 (LKB1) and AMP-activated protein kinase (AMPK). Moreover, the protein expressions of anti-oxidant enzyme and lipolysis were significantly elevated by TST administration. In addition, TST supplementation lowered serum ma-londialdehyde, triglyceride, and total cholesterol levels compared with the control group. Taken together, these data suggest that TST treatment regulated lipid parameters via the increase of β-oxidation by LKB1-AMPK signaling pathway. Conclusions TST may have a potential remedy in the prevention and treatment of obesity. Therefore, this study may provide the scientific basis for TST use. (J Korean Med Rehabil 2021;31(2):1-14)

UV-Vis spectrophotometry법을 이용한 다양한 유지류로부터 헴프씨드 오일의 진위 판별법

이윤진(Yun-Jin Lee),강덕경(Deok-Gyeong Kang),김영민(Young-Min Kim),손호용(Ho-Yong Sohn) 한국생명과학회 2022 생명과학회지 Vol.32 No.5

대마씨의 외종피를 탈각하여 Tetrahydrocanabinol이 제거된 헴프씨드는 건강식품으로 각광받고 있으며, 헴프씨드 오일은 α-linolenic acid 및 γ-linolenic acid 등의 다가 불포화 지방산 및 지용성 비타민 등이 풍부하여, 인지 기능 및 운동기능 개선, 콜레스테롤 감소, 혈관 염증 완화, 혈전 생성 억제, 신경세포 손상 방지 등의 효능이 알려지면서 수요가 급증하고 있다. 현재 헴프씨드 오일은 여타의 식물성 유지(콩기름, 옥수수유, 올리브유, 카놀라유, 아미씨유)보다 45~140배 이상 고가로 판매되고 있다. 본 연구에서는 FTIR, FTIR-Raman, ATR-FTIR-MIR spectroscopy와 같은 고가의 장비와 전문인력에 의한 분석 없이도 헴프씨드 오일의 진위여부를 판별할 수 있는 간편한 UV-Vis spectrophotometry법을 개발하고자 하였으며, 다양한 오일의 245, 305, 및 415 nm 흡광도를 측정하고, 245/415 nm 및 305/415 nm에서의 흡광도의 비를 계산하여 12.9 및 9.6이 나타나는 경우 헴프씨드 오일임을 확인하였다. 콩기름, 옥수수유, 카놀라유 및 아미씨유의 경우에는 각각 35.4~61.8 및 29.7~50.8을 나타내어 헴프씨드 오일과 쉽게 구분 가능하였다. 상기의 방법은 헴프씨드 오일에 여타의 식물성 유지류를 혼합하는 경우에도 혼합 여부 판별에 이용 가능하였다. Hempseed, a dehulled Cannabis fructus, has high nutraceutical potential. It has plenty of essential amino acids, vitamins, and essential polyunsaturated fatty acids, including α- and γ-linolenic acid. Increased exercise capacity, cognitive function, and ameliorative effects against hypercholesterolemia, neuro-inflammation, thrombus formation, and learning and memory impairment were reported in hempseed oil-administered models. Therefore, the market prices of hempseed oil are 45~140-fold higher than the other plant-derived oils, such as soy, corn, olive, canola, or linseed oil. In this study, instead of FTIR (Fourier Transform Infrared Spectroscopy) or FTIR-Raman spectroscopy, a simple UV-Vis spectrophotometry method was developed to authenticate the hempseed oil. Measurements of absorbance at 245, 305, and 415 nm of oils and calculations of 245/415 and 315/415 nm provided that the ratios of 245/415 and 315/415 nm of authentic hempseed oils were 12.9 and 9.6, respectively. The 245/415 and 315/415 nm of soy oil, corn oil, canola oil, and linseed oil were 35.4~61.8 and 29.7~50.8, respectively. This simple UV-Vis spectrophotometry method could also be applied to differentiate hempseed oil from blended oil products in markets.

골다공증을 동반한 하지부골절 수술 후 보행불리 환자 재활에 단순추나요법을 적용한 치험 1례

이윤진(Yun-Jin Lee),박나리(Na-Ri Park),양두화(Doo-Hwa Yang),안희덕(Hee-Duk Ahn) 척추신경추나의학회 2019 척추신경추나의학회지 Vol.14 No.2

Objectives : The purpose of this study was to show the effectiveness of Chuna Manual Therapy applied to a osteoporosis patient with gait disturbance due to lower limb fracture surgery. Method : We focused on Chuna therapy accompanied with acupuncture, herbal medicine, moxibustion, cupping treatment and rehabilitation exercise. This case was assessed using the Visual Analogue Scale (VAS), Pain Free Walking Distance (PFWD), Berg Balance Scale (BBS), and Modified Barthel Index (MBI). Result : This patient showed improvement on the VAS from 6 to 3, PFWD from 0 m to 2000 m using a walker and 50 m by selfwalking, BBS from 2 to 28, and MBI from 56 to 89. Moreover the walking state improved from gait disturbance to self-walking. Conclusion : This study suggests that Chuna therapy could be used to improve gait disturbance in patients with osteoporosis and lower limb fracture surgery.

우리나라 뷰티산업의 문제점과 발전방안

이윤진 ( Yun Jin Lee ),김기영 ( Ki Young Kim ) 한국미용학회 2010 한국미용학회지 Vol.16 No.3

The purpose of this study is to analyze the development ways of beauty industry (hair, nail, skin care, make-up) in korea. To achieve this purpose, this study analyzed the conceptual theory of beauty industry, and positively analyzes the issues of beauty industry. Domestic consumer market with beauty industry was 28,900 billion in 2007, ranked 11th in the world. But there are quite a few problems with beauty industry : smallness of scale, the concentration of a particular industry phenomenon of human resources, the disparity in beauty industry, operating the irrational law and system, insufficient qualification to process the global level, beauty products for the deepening dependence on imports, low awareness, lack of information sharing with related organizations beauty industry, the inadequacy of the various tones of brand operations. Therefore, beauty industry is to solve some of the problems to expand market and to achieve value-added ingredients: the development of raw materials, publicity for the strengthening of the domestic brand awareness, a variety of beauty product design, the join of large company for active expansion of beauty field, meet the global standards system improvement, expansion of overseas markets, the introduction of quality certification system of beauty services industry. So we can improve the international competitiveness of the domestic beauty industry in the global market.

외국인 유학생 대상의 윤리적 글쓰기 지침서 개발 방안

이윤진 ( Lee Yun-jin ) 한국작문학회 2011 작문연구 Vol.0 No.12

이 글은 외국인 유학생을 위한 윤리적 글쓰기 지침서 개발 방안을 모색하는 데에 그 목적이 있다. 최근 국내 대학의 외국인 유학생의 급증으로 학문 목적 한국어 교육 연구가 폭넓게 이루어지고 있으며 그 가운데 학문 목적의 글쓰기 관련 논의가 눈에 띄게 많았다. 그런데 우리는 외국인 유학생이 글쓰기 과정에서 느끼는 여러 가지 애로점이나 다양한 상황들이, 종종 바람직하지 않은 방법으로 결과물을 만들어내는 원인이 되고 있음을 간과해 왔다. 외국인 유학생의 ‘학문 목적의 글쓰기 능력 신장’은 ‘윤리적 글쓰기’를 전제로 하지 않는다면 그 ‘진정성’은 결코 보장될 수 없다. 이에 외국인 유학생의 불충분한 한국어 능력뿐만 아니라 외국인 유학생의 상황이 고려된 윤리적 글쓰기 지침서의 개발이 시급하다. 이 논의에서는 외국인 유학생 대상의 윤리적 글쓰기 지침서의 ‘개발 목표’, ‘개발 원리’, ‘구성 내용’ 등을 중심으로 살펴보았다. 이 글의 결과는 향후 윤리적 글쓰기 지침서 개발하는 데에 기초 자료로 활용 가치가 높을 것으로 기대한다. 아울러 학문 목적의 한국어 교육에서 ‘성실하고 정직한 글쓰기’에 대한 가치를 부각시키고 ‘윤리적 글쓰기’ 실천을 위해 유용하게 쓰일 것이다. 지침서에 포함될 내용 및 실질적인 사례 등은 지속적으로 수집되고 보완되어야 할 것이며, 더욱 심도 있는 논의는 향후 과제로 남기기로 한다. The objective of this study was to inquire into the development of ethical writing guidebook for foreign international students. Lately, in universities within our nation are experiencing a broad scope of study on the education of KAP(Korean for academic purposes) due to the exponential growth in the inflow of foreign students from around the globe. Among everything, the number of articles on writing of KAP(Korean for academic purposes) has increased a manifold. However, we have overlooked the fact that many of the situational differences and difficulties international students come to confront at times are habitually dealt with in an unorthodox way. If the growth of an international student’s writing abilities is not based on a solid premise of ethical writing, its morality cannot be guaranteed. The establishment of a guidebook considering not only an international student’s insufficient Korean skills but also their particular environment is imperative. This article closely examined the ‘the objective’, ‘the prerequisites', ‘structural content’ and other elements behind the development of ethical writing guidebook targeted for foreign international students. The acquired results of this study will serve as the cornerstone to the development of ethical writing guidebook in the future. Thus, it will be useful in emphasizing the importance of 'honest and sincere writing' and practicing ‘ethical writing’ in the writing education of KAP. The contents and examples to be included in the guidebook should be continuously collected and supplemented and deeper discussion into this study will be left for the future.

高麗時代 瓷器盞托 硏究

이윤진(Lee Yun-jin) 한국미술사학회 2012 美術史學硏究 Vol.273 No.273

한방복합치료로 호전된 요추추간판 탈출증 3례

이윤진 ( Lee Yun Jin ),박나리 ( Park Na Ri ),안희덕 ( Ahn Hee Duk ),양두화 ( Yang Doo Hwa ) 대구한의대학교 제한동의학술원 2019 東西醫學 Vol.44 No.2

The purpose of this study was to prove the effectiveness of Korean medical combined treatment for lumbar herniated intervertebral disc(L-HIVD) patients who were admitted to Korean medical hospital. We used acupuncture, herbal medicine, moxa, cupping and chuna treatment. These patients evaluated with visual analog scale(VAS), european quality of life 5 dimension(EQ5D), oswestry disability index(ODI) and pain free walking distance(PFWD). All of these 3 cases of patients showed the improvement of VAS, EQ5D, ODI, PFDW. The results of this study suggest the effectiveness of Korean medical combined treatment for the patients with L-spine disc herniation.