국내 아메리칸 핏불테리어에서 발생한 열사병 증례 보고

이승희,정지열,정재훈,이현경,박중원,이경기,김종완,소병재,윤순식,Lee, Seunghee,Jung, Ji-Youl,Jeong, Jae-Hoon,Lee, Hyunkyoung,Park, Jung-Won,Lee, Kyoung-Ki,Kim, Jong-Hwan,So, ByungJae,Yoon, Soon-Seek 한국동물위생학회 2018 韓國家畜衛生學會誌 Vol.41 No.3

Heat stroke in a dog is a life-threatening syndrome characterized by a high body temperature over $41^{\circ}C$, by the central nervous system dysfunction, and by multiple organ dysfunction. A 11-month-old male American Pit Bull Terrier was presented to clarify the cause of death to diagnostic laboratory. This dog showed clinical signs such as high body temperature ($42^{\circ}C$), severe tachypnea, hematochezia, epistaxis and hemoptysis after transportation at hot summer time. At necropsy, there were hemorrhages in skin, serosa of stomach and small intestine, and also dark red fluid in lumen of intestine. Histopathologic examination revealed extensive hemorrhages in stomach, muscle, skin, and tongue. In microbiology, pathologic bacteria such as Pasteurella, Boedetella, Salmonella, Clostridium, and circulating virus in Korea such as CDV, CIV, CAV, CHV, CCV, CPIV were negative except CPV. There were many gross and microscopic lesions suggesting hest stroke while pathologic agents and related lesions were not detected. Therefore we diagnosed this case as heatstroke.

급성 미로염으로 진단받은 환자의 한방 치험 1례

이승희,강주영,이수경,이창원,Lee, Seung-Hee,Kang, Ju-Young,Lee, Su-Kyung,Lee, Chang-Won 대한한방안이비인후피부과학회 2016 한방안이비인후피부과학회지 Vol.29 No.3

Objectives : The purpose of this study is to report the efficacy of using oriental medical treatment with acute labyrinthitis diagnosed patient.Methods : We experienced one case of acute labyrinthitis diagnosed patient treated with oriental medical treatment. To evaluate the results of this treatment, we measured the hearing recovery, decrease of tinnitus and vertigo. Decrease of tinnitus and vertigo was assessed by THI and Visual Analogue Scale(VAS).Results : VAS of tinnitus decreased from 1.5 to 0.2, and vertigo decreased from 2 to 0. THI decreased from 41 to 25.Conclusions : This study suggests that using oriental medical treatment is effective on Acute labyrinthitis.

알코올로 인한 Wernicke disease의 치험 1례

이승희,라수연,김민석,정희,이유경,이태훈,김경훈,김성균,Lee, Seung-Hee,Ra, Su-Yeon,Kim, Min-Seok,Jung, Hee,Lee, Yu-Gyung,Lee, Tae-Hoon,Kim, Kyeong-Hun,Kim, Sung-Gyun 대한한방내과학회 2001 大韓韓方內科學會誌 Vol.22 No.4

Wernicke Disease is well known of nutriotional disorders Wernicke Disease is charaterized by ataxia, confusion and oculomotor disturbance. We diagnosis one patient, who has ataxia, confusion and oculomotor disturbance as Jusang(酒傷), and gave saenggangunbi-tang, bojungchiseub-tang and samchulgunbi-tang. We observed that clinical symptom and Liver function were improved by these herbal medicine Therefore We consider Wernicke Disease as Jusang(酒傷) and further reports with many case, however, will be needed.

의학교육에서의 가르치는 것과 배우는 것의 의미

이승희,Lee, Seung Hee 연세대학교 의과대학 2009 의학교육논단 Vol.11 No.2

Teaching and learning were carried out long before the word "education" was coined. As teaching and learning became more universal, the word "education" was construed as a social promise, and there was a general consensus as to what it denoted. Many university professors will most likely have great confidence and expertise with respect to "teaching" in their area of specialization, and they believe that they are fulfilling a social promise. However, how much expertise do they have in actually making students "learn"? How concerned are professors about enabling students to utilize their potential and talents to cultivate their learning abilities and to adjust to the different demands of various fields? The same issue arises in medical education. To what extent can professors' teaching heighten students' sense of purpose and motivation to learn? With regard to increasing learners' initiatives, the learning model of constructivism presupposes that learners are active and creative, have their own personalities, and possess unlimited learning potential. The PBL being carried out in medical schools today is a form of study that can take advantage of these aspects of learners. They can maximally widen the range of students' development through many intellectual activities and solve difficult problems by either sharing or critiquing the thoughts and ideas of others. The acts of teaching and learning that have been carried out for thousands of years remain difficult to this day and must be ceaselessly deliberated and researched by experts in the field of education. Just as good teachers are required to produce good learners, we must give ourselves room to rethink the basis of education in order to maximize effective and efficient learning.

IPS(In-Plane Switching) / FFS(Fringe-Field Switching) 기술 진화 소개 및 최근 개발 현황

이승희,Lee, Seung-Hui 한국정보디스플레이학회 2013 인포메이션 디스플레이 Vol.14 No.1

지난 20년 동안 TFT-LCD의 화질은 급격하게 발전해 왔다. 특히 IPS와 VA의 기술경쟁을 통해 서로의 단점을 극복하려는 많은 연구가 수행돼왔다. 하지만 이제는 발광디스플레이의 출현으로 이제는 액정기술 간의 경쟁은 의미 없고 TFT-LCD의 화질/기능/비용면에서 발광디스플레이보다 우수해야 하는 당면 과제를 안고 있다. 현재 IPS기술은 FFS기술을 통해 한층 더 발전하였고 이제는 고화질 제품엔 FFS 채용이 기본화되고 있다. FFS 기술개발에 초기부터 참여하고 지금까지 FFS기술을 연구하고 있는 필자의 관점에서 보면 FFS는 1998년 발표이후 매 6년 마다 중대한 변화가 있었고 그 예가 2004년 히타치사 TV패널에 FFS기술 적용, 2010년 애플사 아이패드에 FFS 기술 채용이다. 현재 기술 흐름으로 볼 때 2016년 정도엔 FFS기술 + 산화물 반도체 + 광배향 기술을 적용한 FFS TV가 시장의 한 축이 되길 필자는 기대해본다. 마지막으로 필자의 경험을 바탕으로 평가한 각 기술들에 대해 다른 전문가들과 이견이 있을 수 있음을 인정하니 많은 양해 부탁드립니다.

양안에 발생한 급성 황반 신경망막병증 1예

이승희,배진성,김윤영,Seung Hee Lee,MD,Jin Sung Bae,MD,Yoon Young Kim,MD,PhD 대한안과학회 2013 대한안과학회지 Vol.54 No.10

Purpose: To report a case of bilateral acute macular neuroretinopathy (AMN) following flu-like illness. Case summary: A 42-year-old woman complained of paracentral scotoma in both eyes 2 weeks after an episode of flu. Fundus examination showed several dark, brown-reddish, wedge- shaped lesions in both maculae, and red-free fundus photography confirmed the lesions. Fluorescein and indocyanine green angiography was normal. Amsler grid test demonstrated paracentral scotoma. The multifocal electroretinogram (ERG) response was subnormal, and ocular coherence tomography (OCT) confirmed an impaired photoreceptor layer in both eyes. Under the diagnosis of AMN, the patient was followed- up without treatment. No subjective changes were observed during follow-up, although the damage to the photoreceptor was partially recovered based on spectral-domain OCT (SD-OCT). Conclusions: Multifocal ERG and SD-OCT may be helpful to diagnose AMN. Despite partial recovery of clinical signs on SD-OCT, paracentral scotoma could be sustained for a long period of time.

환자안전 교육과정 개발 사례 연구

이승희,신좌섭,허남희,윤현배,Lee, Seung-Hee,Shin, Jwa-Seop,Huh, Nam-Hee,Yoon, Hyun Bae 연세대학교 의과대학 2013 의학교육논단 Vol.15 No.3

Patient safety is achieved through systematic improvement based on the knowledge and willingness of medical professionals. A systematic longitudinal curriculum for patient safety is essential to prepare medical students and professionals. The purpose of this article is to introduce our experience with a 'workshop for developing a patient safety curriculum' and to compare the results with previous studies. The workshop comprising 15 medical professors and patient safety experts met for 2 days. The Consensus Workshop method was applied, collecting opinions from all of the members and reaching consensus through the following stages: context, brainstorm, cluster, name, and resolve. The patient safety curriculum was developed by this method, covering patient safety topics and issues, and teaching and assessment methods. A total of 7 topics were extracted, 'activities for patient safety, concepts of patient safety, leadership and teamwork, error disclosure, self-management, patient education, policies.' Issues, teaching methods, and assessment methods were developed for each topic. The patient safety curriculum developed from the workshop was similar to previous curricula developed by other institutions and medical schools. The Consensus Workshop method proved to be an effective approach to developing a patient safety curriculum.

폐밀봉선원 처분시스템 예비 폐쇄후 안전성평가

이승희,김주열,Lee, Seunghee,Kim, Juyoul 한국지하수토양환경학회 2017 지하수토양환경 Vol.22 No.4

An optimum disposal plan of disused sealed radioactive sources (DSRSs) should be established to ensure long-term disposal safety at the low- and intermediate-level radioactive waste (LILW) disposal facility in Gyeongju. In this study, an optimum disposal system was suggested and preliminary post-closure safety assessment was performed. The DSRSs disposal system was composed of a rock cavern and near surface disposal facilities at the Gyeongju LILW disposal facility. The assessment was conducted using GoldSim program, and probabilistic assessment and sensitivity analysis were implemented to evaluate the uncertainties in the input parameters of natural barriers. Deterministic and probabilistic calculations indicated that the maximum dose was below the regulatory limits ($0.1mSvyr^{-1}$ for the normal scenario, $1mSvyr^{-1}$ for the well scenario). It was concluded that the DSRSs disposal system would maintain environmental safety over a long-time. Moreover, the partition coefficient of Np in host rock, Darcy velocity in host rock, and density of the host rock were the most sensitive parameters in predicting exposure dose in the safety assessment.

보폐정천탕(補肺定喘湯)을 이용한 아토피 피부염 치료(治療)에 관한 임상연구

이승희,김장현,Lee Seoung-Hee,Kim Jang-Hyun 대한한방소아과학회 2000 대한한방소아과학회지 Vol.14 No.1

The purpose of this study was on effect of Bopejungcheuntang(BPJC) for atopic dermatitis. During 5 months between January and May 2000, BPJC water extract administered to patient suffering from atopic dermatitis, in Dep. of Pediatrics, Dongguk university Pundang Oriental Hospital and this study was conducted for 27 patient (male 17, female 10) The result were as follows 1. The distribution of remedial values were improvement (51.9%), unresponsiveness(37.0%), depravation(11.1%). 2. After dispensing BPJC, ordinal sites of atopic dermatitis were inner space of elbow and knee joint, face and neck, back and abdomen, wrist and ankle. Befor and after dispensing BPJC this ordinal sites were similar but after dispensing BPJC, the other sites except head is improved. Order of symptomatic improvement is itching, licheniasis, erythema, exudate. Both itching and exudate is significantly improved. 3. According to way of water extract, symptomatic improvement is most excellent with general water extract & distiled water, the second is general water extract, the third is distiled water. 4. BPJC effect on atopic dermatitis is not significantly affected by sex, day of falling ill, medical treatment, resident environment, feeding, character and duration of medical treatment.

스트렙토조토신으로 유도된 신경세포사멸에서 비타민 C의 보호 기전 연구

이승희,한경훈,김현준,박광성,한성희,김정희,허재혁,Lee, Seung-Hee,Han, Kyung-Hoon,Kim, Hyun-Jun,Park, Kwang-Sung,Han, Sung-Hee,Kim, Jung-Hee,Heo, Jae-Hyeok 한국식품영양학회 2018 韓國食品營養學會誌 Vol.31 No.4

In this study, we analyzed the protective effects of the vitamin C in the streptozotocin (STZ)-induced apoptosis using the SH-SY5Y, a neuroblastoma cell line. The cells were pretreated with the vitamin C ($100{\mu}g$) for 30 min, followed by the 24-hr treatment with the 2.5-mM STZ. The cell-viability assay using the Cell Counting Kit (CCK)-8 revealed the cell-survival rate increased by 15% following the vitamin-C pretreatment compared to the STZ-only treatment. Moreover, we conducted the western-blot analysis to determine the protective effect of the vitamin C regarding the apoptosis. Compared to those in the STZ-only-treatment group, the p-ERK and Bcl-2 expressions increased in the vitamin-C-pretreatment group, whereas the p-JNK and Bax expressions decreased. The vitamin-C pretreatment increased the expression of the SOD-1, an antioxidant enzyme, by more than 30%, indicating its protective role in the STZ-induced oxidative stress. Also, we found both the intrinsic- and extrinsic-pathway mechanisms of the STZ-induced apoptosis. The results of this study $s{\mu}ggest$ vitamin C may help prevent the neurodegenerative diseases.