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급성 세관 간질성 신염과 다형 흥반을 동반한 Mycoplasma 감염의 1 예
오종훈,김주호,양동호,홍세용,유병우,이영목,윤석구 대한내과학회 1995 대한내과학회지 Vol.49 No.5
The cause of interstitial nephritis has been recognized being vary heterogenous, including commonly used drug, contrast media and variable systemic infection. Mycoplasma pneumoniae, usually has been regarded as a respiratory pathogen, may cause infection that involves other organs. However renal involvement is very rare. We have experienced a man suffered from Mycoplasma pneumoniae infection associated with pleural effusion, tracheobronchitis, erythema multiforme, and acute tubulointerstitial nephritis. Mycoplasma antibody titers were 1/80 initially, and subsequent titers on four occasions were 1/ 1280, 1/5240, 1/80, 1/40 on hospital day 18, 23, 48 and 64. The renal biopsy which was taken on the 23th day revealed tubulointerstitial nephritis', the skin biosy was compatable with erythema multiforme. The renal function deterioration, measured by serial serum creatinine, has been prolonged more than 2months through our observation period, We report a case in which Mycoplasma pneumoniae infection was considered to be the cause of acute tubulointerstitial nephritis.