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Indomethacin으로 유발된 생쥐의 위점막 손상에 대한 소체환(消滯丸)의 효과
송창훈,백태현,Song, Chang-Hoon,Baek, Tae-Hyeun 대한한방내과학회 2010 大韓韓方內科學會誌 Vol.31 No.3
Objectives : This study was carried out to investigate the effects of Soche-hwan extract on indomethacin-induced gastric mucosal lesions of mice. Methods : Experimental mice were divided randomly into four groups. The normal group, the gastropathy group of gastro-inflammation elicited mice, the misoprostol group of mice administered misoprostol after gastro-inflammation elicitation and the Soche-hwan group of mice administered Soche-hwan after gastro-inflammation elicitation. Results : The hemorrhagic erosion of gastric mucosa, the damage of arrangement of mucous secreted cells and HSP70 increased in the gastro-inflammation elicited group, but decreased significantly in the misoprostol and Soche-hwan extract administered groups. Cell proliferation of gastric mucosa decreased in the gastro-inflammation elicited group, but increased significantly in the misoprostol and Soche-hwan extract administered groups. The distribution of mucosal neck cells and mucosal surface cells and PNA positive reactions of surface mucus cells decreased in the gastro-inflammation elicited group, but increased significantly in the misoprostol and Soche-hwan extract administered groups. COX-1 positive cells decreased in the gastro-inflammation elicited group, but increased significantly in the misoprostol and Soche-hwan extract administered groups. iNOS mRNA and COX-2 mRNA increased in the gastro-inflammation elicited group, but decreased significantly in the Soche-hwan extract administered group. NF-kB p65, iNOS and COX-2 increased in the gastro-inflammation elicited group, but decreased significantly in the misoprostol and Soche-hwan extract administered groups. Conclusion : Soche-hwan extract had excellent effects on indomethacin-induced gastric mucosal lesions in mice.
미만성 축삭 손상으로 유발된 속발성 치매 환자 1례에 대한 증례 보고
송창훈,정종진,오성원,김수연,이상민,정명숙,백태현,이슬희,Song, Chang-Hoon,Jeong, Jong-Jin,Oh, Sung-Won,Kim, Soo-Yeon,Lee, Sang-Min,Jung, Myong-Suk,Baek, Tae-Hyun,Lee, Seul-Hee 대한한방내과학회 2007 大韓韓方內科學會誌 Vol.28 No.3
The purpose of this study is to present a case of secondary dementia caused by diffuse axonal injury. We diagnosed this patient with diffuse axonal injury by using brain computerized tomography(CT) and magnetic resonance imaging(MRI), and also diagnosed secondary dementia based on DSM-IV. To evaluate prognosis of the patient, we used K-DRS(Korean-Dementia Rating Scale) and gave him a written test. As a result of treating this patient with oriental medicine, the K-DRS score increased and the overall clinical symptoms improved. In oriental medicine, case studies of diffuse axonal injury are yet insufficient, hence more clinical studies and researches will be needed.
송창훈,이슬희,오성원,정종진,김수연,이상민,조성언,선승호,황진우,백태현,Song, Chang-Hoon,Lee, Seul-Hee,Oh, Sung-Won,Jeong, Jong-Jin,Kim, Soo-Yeon,Lee, Sang-Min,Cho, Sung-Eun,Sun, Seung-Ho,Hwang, Jin-Woo,Baek, Tae-Hyun 대한한방내과학회 2007 大韓韓方內科學會誌 Vol.28 No.2
Objectives and Methods : Chronic pancreatitis is an inflammative disease characterized by both persistent and irreversible progression of pancreatic lesions that accompanies complications and pain which hinders everyday life activities. As the alcohol consuming population increases, chronic pancreatitis is increasing consequently. We retrospectively analyzed the medical record of a chronic pancreatitis patient who had been treated with oriental herbal medicine, acupuncture and moxibustion for 40 days. He complained of anorexia, fatigue, indigestion, weight loss, constipation, abdominal discomfort and pain. We prescribed him Daekumeumja, Bojungikgi-tang and other oriental herbal medicines in order to cure these symptoms. Results and Conclusion : For 40 days he was treated with oriental medicine and the symptoms mostly disappeared. When it comes to the therapeutic effects, it could be suggested that oriental medicine has significant effects on improving symptoms and qualities of lives.
송창훈,이슬희,김정철,오성원,정종진,황진우,백태현,Song, Chang-Hoon,Lee, Seul-Hee,Kim, Jung-Chul,Oh, Sung-Won,Jeong, Jong-Jin,Hwang, Jin-Woo,Baek, Tae-Hyun 대한한방내과학회 2006 大韓韓方內科學會誌 Vol.27 No.3
Objectives : This study was designed to evaluate the effects of oriental treatment on cancer patients. Methods : We retrospectively analyzed the medical record of a distal cholangiocarcinoma patient who had been treated with oriental medicine for 150 days. He complained of anorexia, dyspepsia, fatigue, weight loss, constipation, abdominal discomfort and pain. etc. We prescribed him Samchulkunbi-tang and other oriental medicines, in order to treat symptoms and improve long term survival. Results and Conclusion : For 150 days, he was treated with oriental medicine and the symptoms mostly disappeared. We had a worthwhile improvement of long term survival. When it comes to therapeutic effects, it could be suggested that oriental medicine has significant effects on improving symptoms, survival and quality of lifes.
[연료 및 윤활유부문] 4사이클 엔진 배기시스템의 소음저감 성능에 관한 실험적 연구
송창훈(Chang-hoon Song),이해철(Hae-Chul Lee),윤준규(Jun-Kyu Yoon),차경옥(Kyung-Ok Cha) 한국자동차공학회 2000 한국자동차공학회 춘 추계 학술대회 논문집 Vol.- No.-
In vehicle exhaust systems the sound attenuation and the reduction of flow losses are often two competing demands. The present study considers a fully vehicle exhaust system and investigates experimentally both the sound attenuation and the flow performance of production configurations including the catalyst, the resonator, and the muffler. Dynamometer experiments have been conducted with 1500cc engine with speeds ranging from 1000 to 5000 rpm, Measurements include the flow rates, the temperatures and the absolute dynamic pressures of the hot exhaust gases at point locations. The present study describes the experimental aspects of an ongoing effort to validate and use the nonlinear fluid dynamic models in the time-domain for the prediction of the acoustic and power performance of firing internal combustion engines with full production exhaust systems
기관지천식에 있어서 흡입성 Fenoterol 과 Ipratropium Bromide 의 기도확장효과 비교
송창훈(Chang Hoon Song),양재범(Jae Beom Yang),김영철(Young Chul Kim),김정일(Jung Il Kim),오춘수(Choon Soo Oh),이춘기(Chon Kee Lee),최인선(In Seon Choi),박경옥(Kyung Ok Park) 대한내과학회 1989 대한내과학회지 Vol.37 No.5
N/A We assessed the bronchodilator effects of inhaled fenoterol and ipratropium and compared them according to the localization of airway obstruction in 37 patients with bronchial asthma. Although FVC and FEV1 increased remarkably at 10 minutes and one hour after each inhalation of fenoterol or ipratropium, there were no significant differences in effects between the two drugs except that there was a more distinguishable response in FEF25~75% at 10 minutes after fenoterol inhalation. In the response group in which Δvma×50 was more than 20%, fenorerol showed more significant increases in FEV, and FEF25~75% than in the nonresponse group, and showed a more marked response of FEF25~75% than that of the ipratropium group at 10 minutes after inhalation, However, at one hour after inhalation, their bronchodilator efficacy was similar without any statistical differences. The above results suggested that the bronchodilator effect of fenoterol occurred more rapidly than that of ipratropium and that both drugs are able to act on the central large airways as weI1 as the peripheral small airways.