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      • 培地 및 培養液의 濃度가 부추의 初期生育에 미치는 影響

        김창연 安東大學 1985 安東大學 論文集 Vol.7 No.1

        부추의 양액 재배시 필요한 기초적인 문제를 구명하기 위하여 배지의 종류(Vermiculite와 Zeolite)와 배양액의 농도(0.5mu와 0.25mu)에 따른 부추의 생체중, 초장 및 건물율을 조사한 결과는 다음과 같다. 1. 생체중은 배지의 종류에 따른 차이는 인정할 수 없었고 배양액의 농도가 높은 쪽이 증가하는 경향을 보였다. 2. 초장은 처리간에 큰 차이를 인정할 수 없었다. 3. 건물율은 Zeolite에서 보다 높게 나타났으며 또 배양액의 농도가 높은 쪽에서 높았다. For the purpose of defining the fundamental necessary problems concerning the growth of chinese leeks, the fresh weight, the length of leaf and the dry matter ratio are examined according to the kinds of media material (Vermiculite and Zeolite) and nutrient concentration (0.5mu and 0. 25mu). The results of the study are as follows; 1. The fresh weight did scarecely change with the different kinds of media material but it increased more with the higher nutrient concentration. 2. For the length of leaf, there were not found any important differences between each of the different treatments. 3. The dry matter ratio appeared higher with Zeolite and also higher with higher nutrient concentration.

      • Norinyle 服用이 體內代謝에 미치는 影響에 關한 硏究

        金昌淵,朱軫淳 고려대학교 의과대학 1980 고려대 의대 잡지 Vol.17 No.1

        In order to observe metabolic effects of an oral conceptive, Norinyle, on female guinea pig, the changes of ascorbic acid amount and alkaline phosphatase activity in the liver and serum were determined, and histochemical changes of the uterus were observed by a microscopic and electronmicroscopic methods by administration of Norinyle with or without ascorbic acid. The results obtained are summarized as follows: 1. The metabolic changes were clearly influenced by the administration of Norinyle alone, but the changes were diminished by administration of Norinyle with ascorbic acid. 2. The administration of Norinyle influenced to increases the requirement of ascorbic acid in the liver. 3. The uterus weight of the Norinyle administrated group was much increased, while the weight was less increased in the group of administrated Norinyle with ascorbic acid than the control. 4. The Norinyle administration was brought about an atrophy of endometrium of uterus especially, functional layer, that the formation of glands were inadequately and the formation of basal layer and stroma were diminished. 5. An acute infraction on the all layers of the uterus was developed at 9th and 25th days of Norinyle administration and 20th day of Norinyle with ascorbic acid administration. 6. A hypertrophy of stromal and endovasular cells were observed on the groups administered of Norinyse alone (Group Ⅱ) or Norinyle with ascorbic acid (Group Ⅳ). 7. It was observed that the amount of collagen fiber in the basal and muscular layeres of uterus were diminished under a microscopical observation by the special stained specimen on the Norinyle administered group, but the amount and distribution of reticulin fiber were not changed significantly. 8. The fine structure of outer functional layer of the uterus were significantly changed by the administration of Norinyle which were shown irregurarity of nuclear membrane, poor development and significant expansion of endoplasmic reticulum, decreases of the amount of ribosome due to slip off, increase of the number of dense bodies, obvious formation of vaccule, and decreases the amount of collagen in inner and outer layer of the stroma. 9. The amount of ascorbic acid in the serum did not much changed but the amount in the liver was much decreased by the administration of Norinyle. And the administration of Norinyle with ascorbic acid induced for a significant diminishing on the changes of uterus which might be able to developed by the administration of Norinyle alone.

      • KCI등재

        광학현미경과 투과전자현미경을 이용한 토끼와 닭 대퇴골의 미세구조 분석

        김창연,김은경,전태훈,남승원,김윤중,Kim, Chang-Yeon,Kim, Eun-Kyung,Jeon, Tae-Hoon,Nam, Seung-Won,Kim, Youn-Joong 한국현미경학회 2010 Applied microscopy Vol.40 No.3

        뼈는 단계별 (hierarchical) 구조를 가진 복합 재료이며 독특한 구조와 기계적 특성 때문에 재료공학 분야에서 많이 연구되어져 왔다. 뼈는 주로 hydroxyapatite, 콜라겐과 물로 구성된 층판형 유 무기 재료 복합체이다. 주요 무기물로써 hydroxyapatite로 잘 알려진 calcium phosphate를 통하여 뼈는 특유의 강도를 유지하게 된다. 본 실험에서는 광학 현미경(LM)과 투과전자현미경(TEM)을 이용하여 토끼와 닭 대퇴골의 구조를 연구하였다. 구성물질 분석은 대퇴골의 calcium, potassium, oxygen 분포 변화를 알아보는데 이용하였다. 실험은 두 구조 범위에 중점을 두었다: micro scale에서 치밀골의 배열을, nano scale에서 콜라겐 섬유와 apatite 결정을 관찰하였다. Micro scale에서 닭과 토끼 대퇴골 구조의 뚜렷한 차이점이 발견되었다. Nano scale에서는 apatite 결정의 모양과 크기 그리고 콜라겐의 배열을 비교 분석하였다. 그 결과 토끼와 닭은 종이 다름에도 불구하고 nano scale에서는 화학성분과 구조가 매우 유사한 것으로 나타났다. Bone is a hierarchically structured composite material which has been well studied by the materials engineering community because of its unique structure and mechanical properties. Bone is a laminated organic-inorganic composite composed of primarily hydroxyapatite, collagen and water. The main mineral that gives bone's hardness is calcium phosphate, which is also known as hydroxyapatite. Light microscopy (LM) and transmission electron microscopy (TEM) were used to study the structure of femurs from chicken and rabbit. The elemental analysis was used to search variation in the distribution of calcium, potassium and oxygen in the femur. Current investigation focused on two structural scales: micro scale (arrangement of compact bone) and nano scale (collagen fibril and apatite crystals). At micro scale, distinct difference was found in microstructures of chicken femur and rabbit femur. At nano scale, we analyzed the shape and size of apatite crystals and the arrangement of collagen fibril. Consequently, femurs of chicken and rabbit had very similar chemical property and structures at nano scale despite of their different species.

      • KCI등재

        405nm GaN-LED 고 휘도화에 의한 백색 발광 다이오드의 특성 향상

        김창연,김성진,김송강,유순재,최용석,한영현 한국물리학회 2005 새물리 Vol.50 No.3

        We demonstrate a light conversion white light-emitting diode (LED) for general illumination applications. The white LED was fabricated by combining a 405 nm LED with three phosphors,yellow-red, blue, and green. In order to achieve a high light-output power from the LED, we fabricated the 405 nm LED with a 1 1 mm2 device size. The light-output power of 405 nm LED was dramatically improved not only by introducing an indium tin oxide (ITO) transparent metal electrode (TME) but also by growing the LED with a lateral epitaxial structure on a patterned sapphire substrate (LEPS). The ITO TME and the LEPS will improved the light-extraction eciency due to the better optical transmittance the lateral current spreading due to the lower lateral resistance, and the internal quantum eciency (IQE) due to a better crystal quality. The light-output power of the 405 nm LED was as large as 112 mW at a 350 mA junction current. A maximum external quantum eciency (EQE) as large as 13.4 % was obtained under a 200 mA junction current. The white LED consisting of a 405 nm LED and three phosphors yellow-red, blue, and green proved to have be excellent device performance with CCT = 5,596 K, luminous ux = 15.6 lm (11.4 lm/W), color index CIE x = 0.3304 and y = 0.3254, and CRI = 84.4.

      • 다층 기판 위에 표면실장된 SRAM 모듈 설계 제작

        김창연,지용,Kim, Chang-Yeon,Jee, Yong 대한전자공학회 1995 전자공학회논문지-A Vol.32 No.3

        In this paper, we ecamined the effect that MCM-L technique influencess on the design and fabrication of multichip memory modules in increasing the packing desity of memory capacity and maximizing its electrical characteristics. For that purpose, we examined the effective methods of reducing the area of module layout and the wiring length with the variation of chip allocation and the number of wiring layers. We fabricated a 256K${\times}$8bit SRAM module with eight 32K${\times}$8bit SRAM chips. The routing experiment showed that we could optimize the area of module layout and wiring length by placing chips in a row, arranging module I/O pads parallel to chip I/O pads, and equalizing the number of terminal sides of module I/O's to that of chip I/O's. The routing was optimized when we used three wire layers in case of one sided chip mounting or five wire layers in case of double sided chip mounting. The fabricated modules showed 18.9 cm/cm$^{2}$ in wiring density, 65 % in substrate occupancy efficiency, and module substrate and functionally tested to find out the module working perfectly.

      • KCI등재

        필러에 대한 개략: 성분, 효과, 유동학적 특징을 중심으로

        김창연 대한미용성형외과학회 2011 Archives of Aesthetic Plastic Surgery Vol.17 No.1

        As increasing demands for facial soft tissue augmentation by injection and minimal invasive procedures, filler has become increasingly popular and a suitable method for patients’ demands. Over several decades, many filler products have been introduced. Successful clinical application of filler products requires a thorough understanding of their compositions, effects, and rheology. This study reviewed filler products according to the classification of effect duration: permanent, semipermanent, temporary.

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