http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
- 中文 을 입력하시려면 zhongwen을 입력하시고 space를누르시면됩니다.
- 北京 을 입력하시려면 beijing을 입력하시고 space를 누르시면 됩니다.
RISS 인기검색어
- 검색키워드
- 저자 : 김재군(Jae-Kun Kim) (검색결과 114 건)
- 무료
- 기관 내 무료
- 유료
-
급성 골수성 백혈병에서 고용량 Cytarabine 을 이용한 공고요법
김도하(Do Ha Kim),이규형(Kyoo Hyung Lee),조재근(Jae Kun Cho),김선희(Seon Hee Kim),이제환(Je Hwan Lee),김성배(Sung Bae Kim),김상위(Sang We Kim),서철원(Chul Won Suh),이정신(Jung Shin Lee),김우건(Woo Kun Kim),김상희(Sang Hee Kim) 대한내과학회 1996 대한내과학회지 Vol.51 No.4
Objectives: This study was designed to evaluate the therapeutic efficacy of postremission therapy utilizing high-dose cytarabine in patients with newly diagnosed acute myelogenous leukemia and to assess the toxicities of the therapy. Acute promyelocytic leukemia (FAB M3) is excluded because it has very unique clinicopathologic characteristics. Methods: Those patients who achieved complete remission had first consolidation therapy with conventional dose cytarabine and daunorubicin but second and third consolidation was done with high-dose cytarabine (cytarabine 1gm/㎡ i.v. over 1 hour every 12 hours daily for 5 days) and daunorubicin. Overall survival and disease free survival were compared with previous conventional dose cytarabine and daunorubicin postremission therapy. Results: 1) Complete remission occurred in 62% (28 of 45 patients) and control group 48% (14 of 29 patients) (p=0.15). 2) The median survival of all 45 patients was not different significantly compared with control group (10 months vs 7 months, p=0.08). 3) The median disease free survival of 21 complete responders receiving at least one course of consolidation was 10 months and there was no significant difference compared with control group 7 months (p=0.47). 4) The toxicity including treatment-related motility, neutropenia duration was similar in both groups. Conclusion: Although our high-dose cytarabine consolidation therapy regimen appeared to have acceptable toxicity, its results did not show the superiority to previous conventional dose cytarabine consolidation regimen.
-
-
토끼 태아에서 표피성장인자 투여가 코티졸 , 티록신 , 프로락틴의 생성에 미치는 영향
김수평(Soo Pyung Kim),신종철(Jong Chul Shin),이종건(Jong Kun Lee),김용욱(Yong Wook Kim),변태섭(Tae Sup Byun),신재인(Jae In Shin),이종승(Chong Seong Yi),나종구(Jong Gu Rha) 대한산부인과학회 1998 Obstetrics & Gynecology Science Vol.41 No.12
Respiratory distress syndrome (RDS) is a major cause of death in premature neonates, and it is caused by the failure of morphological and biochemical lung maturation (synthesis and secretion of lung surfactant). It is known that cortisol, thyroxine, prolactin, epidermal growth factor (EGF), and estrogen accelerate the lung maturation. Cortisol and thyroxine are currently used in the antenatal treatment for the prevention of RDS in premature neonates. In order to evaluate the effect of EGF on the levels of cortsol, thyroxine, and prolactin, this study was undertaken. Phosphate buffered saline (PBS) with and without EGF was directly injected into the 25 days gestational fetus in uterus. Blood was collected for the measurement of cortisol, thyroxine, and prolactin one day or two days after the injection. Body weights and lung weights were also measured. The results were as follows: 1. There was no significant difference in body weights and lung weights between PBS-treated group(control group) and EGF-treated poup(experimental group), 24 hours and 48 hours after the injection. 2. 24 hours after the injection, the levels of cortisol were significantly inaeased in the EGF-treated group compared with those in the PBS-treated group. However 48 hours after the injection, there was no significant difference in the levels of cortisol between the two groups. The levels of thyroxine and prolactin in the EGF-treated group did not significantly differ from those in the PBS-treated group 24 hours and 48 hours after the injection. In conclusion, in vivo, the synthesis of cortisol may be affected by EGF treatment, which suggests that the action of EGF for lung maturation may be partially mediated by the increased endogenous levels of cortisol.
-
-
급성 심근 경색 환자에서 좌심실 기능 , 좌심방 기능 및 폐정맥 혈류 양상의 변화
김복근(Bok Kun Kim),주승재(Seung Jae Joo),배영환(Young Hwan Bae),박선미(Sun Mi Park),최진(Jin Choi),최휘(Hwi Choi),윤병철(Byung Chul Yoon),오원섭(Won Sub Oh),구양훈(Yang Hwun Koo),홍성준(Sung Jun Hong),김진(Jin Kim),박능화(Neung Hwa 대한내과학회 1997 대한내과학회지 Vol.53 No.6
Objectives: Acute myocardial infarction decreases left ventricular systolic and diastolic function. Left ventricular diastolic function is usually assessed with the left ventricular filling patterns. Abnormal left ventricular tilling patterns after acute myocardial infarction can be classified as relaxation abnormality, pseudonormalization, and restriction, but sometimes the differentiation between pseudonormalization and the normal pattern is difficult. To assess left ventricular systolic and diastolic function, and left atrial function after acute myocardial infarction, M-mode, two-dimensional, pulsed Doppler, and automated border detection echocardiography were performed. To complement the information obtainable from the mitral flow patterns, pulmonary venous flow patterns were also analysed to assess the left ventricular filling patterns. Methods: Twenty six patients (mean age 60 ±10) underwent echocardiographic examination 7 to 14 days after acute myocardial infarction. Twenty healthy persons(mean age 57±12) were served as a control group. Various indexes were obtained with M-mode, two-dimensional, pulsed Doppler, and automated border detection echocardiography Results: 1) Mean age, sex ratio, heart rate, body mass index were not different between patient and control groups. There were five patients with hypertension in patient group. Left ventricular mass index of patient group was greater than that of control group (163±43g/㎡ vs. 109±22g/㎡, P<0.0D1). 2) Patients had decreased cardiac index(2.35±0.53L/min/㎡ vs. 3.02±0.70L/min/㎡, P<0.05) and left ventricular ejection fraction(55±12% vs. 62± 0.4%). There was a negative correlation between left ventricular regional wall motion score and ejection fraction(r=-0.71; P<0.001). 3) In patients, peak mitral flow velocity at atrial contraction(A) was higher(73±11cm/sec vs. 63±13 cm/sec; P<0.01), E/A ratio was lower(0.77±0.28 vs. 1.01±0.25; P<0.01), and left ventricular isovolumic relaxation time was longer(126±34msec vs. 97±21msec; P<0.005). 4) Patients had smaller systolic time-velocity integral(13.0±3.30cm vs. 14.8±2.83cm, P=0.056) and diastolic time--velocity integral(9.18±2.21cm vs. 11.2±2.77cm, P<0.01). 5) Relaxation abnormality of left ventricular filling patterns, which was classified by E/A ratio of less than 1, was more frequently founded in patients than in controls(45%). Four patients had E/A ratio of greater than 1; SV/DV ratio was greater than 1 in two and less than 1 in others. 6) End-diastolic area of left atrium(minimal area) was larger in patients(11±1.9㎠ vs. 9.6+1.4㎠, P<0.01). Therefore, patients showed decreased atrial emptying index and expansion index. Patients had a greater extent of left atrial area decrease resulting from atrial contraction. Conclusion: Patients with acute myocardial infarction showed a decreased left ventricular systolic function and a relaxation abnormality 7 to 14 days after attack, Minimal area of left atrium increased and left atrial function decreased.
-
-
-
-
-
동부류 근류균(根瘤菌)의 땅콩에 대한 근류형성(根瘤形成)과 질소고정(窒素固定)
김무기,박건호,소재돈,최대웅,Kim, Moo-Key,Park, Kun-Ho,So, Jae-Don,Choi, Dae-Ung 한국토양비료학회 1992 한국토양비료학회지 Vol.25 No.1
Glasshouse experiments were conducted to evaluate nodulation, and $N_2$ fixation of 73 strains of Bradyrhizobia isolated from nodules of groundnuts and/or cowpeas grown at various location in Korea and 31 strains of cowpea Bradyrhizobia obtained from overseas sources. Of the strains tested 51.9%, 26.4%, and 21.7% were rated fully effective, partially effective, and ineffective, respectively. Eight very effective strains were selected. Nodulation, shoot dry mass, whole plant dry mass, and plant total N content were significantly correlated with each other. The highly significant correlation of total N content and plant dry mass ($r=0.98^{**}$) indicates that plant dry mass can be used as a measure of strain effectiveness in preliminary test.
ScienceON연관 검색어 추천
이 검색어로 많이 본 자료
활용도 높은 자료
