기관지내 발생한 과오종치험 1례

김영호,김수성,김공수,Kim, Yeong-Ho,Kim, Su-Seong,Kim, Gong-Su 대한흉부심장혈관외과학회 1983 Journal of Chest Surgery (J Chest Surg) Vol.16 No.1

The origin of hamartoma from the Greek words for "error" and "tumor" is credited to Albrecht who in 1904 described a disorganized arrangement of tissues normally present in an organ and applied also to tumors found in many organs other than the lung. The hamartoma is the most common benign tumor of the lung and revealed accidentally as asymptomatic coin lesion on routine chest X-ray, but the incidence is very low and especially endobronchial origin extremely low. We have been successful surgical experienced one case of a 36-year-old female having endobronchial hamartoma, 4x2.Sx2 cm in size and located at right main bronchial lumen near the carina, which consists of a hard, nodular surfaced mass and adhered to the cartilaginous portion of the right upper lobe bronchus by dense fibrous band and migrate to trachea on expiration or coughing. This case was not suspected by chest X-ray or bronchogram and confirmed bronchoscopy with biopsy. Right pneumonectomy was inevitable because of bronchiectatic change of right bronchus due to tumor obstruction. She was discharged with relatively good general condition on 21 days postoperatively.

Watersheds 기반 계층적 이진화를 이용한 단백질 반점 분할 알고리즘

김영호,김정자,김대현,원용관,Kim Youngho,Kim JungJa,Kim Daehyun,Won Yonggwan 한국정보처리학회 2005 정보처리학회논문지B Vol.12 No.3

생물학자가 단백질을 검색하고 분석하기 위해서는 2차원 젤 전기영동(2DGE : Two Dimensional Gel Electrophoresis) 실험을 해야 한다. 실험 결과는 2차원 영상이 생성된다. 2차원 영상에서 단백질 반점의 패턴 분석을 위해 2차원 젤 영상에 펼쳐진 단백질 반점들을 영상처리를 통해 분할하고, 대조 그룹의 단백질 패턴과 비교분석을 통해 밝히고자하는 단백질 반점을 찾아내야 한다. 단백질 반점을 분할하는 알고리즘에 있어서 기존에는 가우시안 함수를 적용하였지만, 최근 들어 형태학 분리개념에 의한 Watersheds 영역기반 분할(Watersheds region-based segmentation) 알고리즘을 활용하고 있다. 그러나 Watersheds 영역기반 분할 알고리즘은 크기가 큰 영상에서 원하는 영역을 신속하게 분할한다는 장점이 있지만, 영상 화소의 그레이 값이 연속적인 경우 실제 반점의 개수 에 비해 과다분할(over-segmentation)되거나 과소분할(under-segmentation)의 문제점을 안고 있다. 이는 마커(marker) 포인트의 설정에 의해 어느 정도 해결할 수 있지만 병합(merge)과 분할(split) 과정을 반복해야 한다. 본 논문은 Watersheds 기반 계층적 이진화 기법을 적용하여 마커 드리븐 Watersheds 영상분할의 문제점을 해결하고자 한다. Biologist must have to do 2DGE biological experiment for Protein Search and Analysis. This experiment coming into being 2 dimensional image. 2DGE (2D Gel Electrophoresis : two dimensional gel electrophoresis) image is the most widely used method for isolating of the objective protein by comparative analysis of the protein spot pattern in the gel plane. The process of protein spot analysis, firstly segment protein spots that are spread in 2D gel plane by image processing and can find important protein spots through comparative analysis with protein pattern of contrast group. In the algorithm which detect protein spots, previous 2DGE image analysis is applies gaussian fitting, however recently Watersheds region based segmentation algorithm, which is based on morphological segmentation is applied. Watersheds has the benefit that segment rapidly needed field in big sized image, however has under-segmentation and over-segmentation of spot area when gray level is continuous. The drawback was somewhat solved by marker point institution, but needs the split and merge process. This paper introduces a novel marker search of protein spots by watersheds-based hierarchical threshold, which can resolve the problem of marker-driven watersheds.

팽이버섯 분열자의 생성원인 및 특성

김영호,공원식,김경수,유창현,김한경,성재모,류영진,김광호 ( Young Ho Kim,Won Sik Kong,Kyung Soo Kim,Chang Hyun You,Han Kyoung Kim,Jae Mo Sung,Young Jin Ryu,Kwang Ho Kim ) 한국균학회 1998 韓國菌學會誌 Vol.26 No.2

실크펩티드를 첨가한 빵이 Rat의 지질대사에 미치는 영향

김영호,조남지,Kim, Young-Ho,Cho, Nam-Ji 동아시아식생활학회 2007 동아시아식생활학회지 Vol.17 No.2

The aim of this study was to investigate the effect of bread supplemented with silkpeptide and cholesterol of on the lipid metabolism in rats. When a rats were fed bread supplemented with silkpeptide and cholesterol, their net weight tended to decrease compared with the control. Although the food intake was increased, this was not significant., but the feed efficiency ratio was substantially decreased. The total and LDL-cholesterols were decreased, but the DHL-cholesterol was increased. The HDL-cholesterol to total cholesterol ratio and level of triglyceride were substantially increased. The atherogenic index was decreased when rats are fed bread supplemented with silkpeptide and; thus, would show an improvement in the effect of high-cholesterol symptoms.

기술사법의 현황과 개선방안

김영호,Kim, Yeong-Ho 한국설비기술협회 1994 설비 : 공조ㆍ냉동ㆍ위생 Vol.11 No.10

고주파 반응성 스퍼터링에 의해 제작된 InN 박막의 특성

김영호,최영복,정성훈,홍필영,문동찬,김선태,Kim, Young-Ho,Choi, Young-Bok,Chung, Sung-Hoon,Hong, Pil-Young,Moon, Dong-Chan,Kim, Sun-Tae 한국전기전자재료학회 1998 전기전자재료학회논문지 Vol.11 No.7

Thin film deposition of InN, which is a less-studied III-nitride compound semiconductor because of the difficulty if crystal growth, was performed by rf reactive sputtering method using In target and $N_2$reactive gas. The structrual, electrical, and optical properties of the produced films were measured and disussed according to the sputtering parameters such as deposition pressure, rf power, and substrate temperature. From the result of deposition pressure, rf power, and substrate temperature, we could obtain optimal conditions of 5m Torr, 60W, $60^{\circ}C$ for preparing InN thin film with high crystallinity, low carrier concentration, and high Hall mobility. The carrier concentration, Hall mobility, and optical bandgap of the fabricated InN thin films at optimal condition were $6.242\times10^{18}cm^{-3}, 212.526cm^2/V\cdot$s, and 1.912eV, respectively.

최근의 CCITT 연구활동 분석

김영호,이윤철,Kim, Yeong-Ho,Lee, Yun-Cheol 한국전자통신연구원 1984 전자통신 Vol.6 No.3

최근의 CCITT 연구활동을 조사.분석하기 위하여 CCITT의 구성과 각 연구위원회 (Study Group;SG)의 7차회기 ('81~'84)동안의 연구 내용 및 SG VII (데이터통신망), SG VIII (텔리매틱 서어비스를 위한 첨말장치), SG XI (전화교환과 신호방식), SG XVIII (디지틀망)의 최종회합에서 작성된 근고초안을 검토.분석하여 기술하였다.

지역난방공급방식 공동주택의 유량조절장치 설치 시공 지침 해설

김영호,Kim, Yeong-Ho 한국설비기술협회 1994 설비 : 공조ㆍ냉동ㆍ위생 Vol.11 No.2

수용성카이토산에 의한 마우스태반을 통한 태아로의 방사성스트론튬 급성 전이 억제

김영호,범희승,김지열,Kim, Young-Ho,Bom, Hee-Seung,Kim, Ji-Yeul 대한방사선방어학회 1997 방사선방어학회지 Vol.22 No.4

카이토산은 천연무독성 착화제의 일종으로 유전적 독성이 거의 없으며, 방사성스트론튬의 마우스 체내 축적을 감소시킨다고 알려져 왔다. 본 연구에서는 임신 17일째 마우스에서 방사성스트론튬 오염전 후에 수용성카이토산을 공급함으로써 오염 후 태반을 통한 태아로의 방사성스트론튬 급성 전이를 얼마나 효과적으로 억제할 수 있는 가를 알아보고자 하였다. 수용성카이토산 분말을 50일간 일반식이와 혼합하여 10% (Group 1), 1%(Group 2)를 공급하고 임신 17일째에 방사성스트론튬을 오염시킨 군의 경우 일반식이를 공급한 대조군과 방사성스트론튬 오염 후 카이토산 10%, 1%분말을 공급한 군(Group 3, Group 4)에 비해 태반을 통한 태아로의 방사성스트론튬 전이를 효과적으로 억제함을 관찰하였다(p<0.01, 표 1).본 실험을 통해서 임신 17일째에 방사성스트론튬에 오염된 임신마우스의 경우 천연무독성 착화제인 카이토산을 장기간 전처치하였을 경우 태반을 통한 태아로의 방사성스트론튬 전이를 억제할 수 있음을 알 수 있었다. It has been reported that chitosan has little genetic toxicity as one of natural and nontoxic chelator and reduces the internal retention of radiostrontium in the mouse. This study is to examine that when water soluble chitosan is provided to the mouse on 17 days of pregnancy before and after radiostrontium contamination, how effectively it can inhibit an acute transfer of radiostrontium to fetus through placenta contaminated. Water soluble chitosan powder is mixed with general food for 60 days and 10%(Group 1) and 1%(Group 2) are provided respectively, and it is observed that the group with radiostrontium contamination on 17 days of pregnancy can inhibit more effectively the transfer of radiostrontium to fetus through placenta than control group with general food and the groups (Group 3, Group 4) with 10% and 1% of chitosan powder respectively after radiostrontium contamination (p<0.01, Table 1). It is found that when the pregnant mouse contaminated by radiostrontium on 17 days of pregnancy is prefed by chitosan, the transfer of radiostrontium to fetus through placenta can be inhibited.

천련자로부터 분리한 Limonoid 성분의 세포독성

김영호,황방연,김세은,김환묵,오구택,노재섭,이경순,이정준,Km, Young-Ho,Hwang, Bang-Yeon,Kim, Se-Eun,Kim, Hwan-Mook,Oh, Goo-Taeg,Ro, Jai-Seup,Lee, Kyong-Soon,Lee, Jung-Joon 대한약학회 1994 약학회지 Vol.38 No.1

The MeOH extract of the fruits of Melia toosendan was selected for futher study by its cytotoxicity and effect on the human breast cancer cell line, MCF-7. The active principle obtained by activity guided fractionation followed by purification gave rise to a needle crystal. The structure was deduced by employing NMR and was determined to be identical with 28-deacetyl sendanin by comparison with published data. This compound induced morphological change of MCF-7 to be rounded with tubule at concentrations between $50\;{\mu}g/ml$ and $0.025\;{\mu}g/ml$. This compound, however, showed strong cytotoxic effect on Hepalclc7 and HepG2, and their $GI_{50}$ on the hepatoma cell lines were $0.238\;{\mu}g/ml$ and $0.805\;{\mu}g/ml$, respectively. Its effect on lymphocyte of mouse was stronger than hepatoma cell lines, and their $ED_{50}$ of polyclonal antibody response was $0.011\;{\mu}g/ml$, and $ED_{50}$ of cell viability was $0.039\;{\mu}g/ml$.