http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
김성근,박조현,김경미,Jaegue Kim,김형호,박원상,Jongjae Park,이문수,정현철,Hunyong Jung,한상욱,형우진,류성엽,김욱,Junghwan Yook,Heicheul Jeung,정인호,Dojoong Park,오상훈,Keunwon Ryu,진형민 대한위암학회 2010 Journal of gastric cancer Vol.10 No.3
We have always attempted to create a standard treatment protocol for patients with gastric cancer. However, many debates still exist regarding gastric cancer treatment. For the past 2 years, at the Annual Congress of the Korean Gastric Cancer Association, we have presented a grand symposium on the “Debates on the strategy for treating gastric cancer”. In 2008, four major topics were discussed and voted on after discussion. The four major topics were proximal location treatment for early gastric cancer, management choices for pyloric obstruction with advanced gastric cancer, management of liver metastasis, and reconstruction methods after a distal gastrectomy. The opinions of the audience for six minor topics were expressed by an electronic voting system. In 2009, the four main topics were treatment for submucosal tumor sized around 2 cm, laparoscopic gastrectomy in T2N1 gastric cancer, choices for managing gastric lymphoma,and application of a pylorus preserving procedure for early gastric cancer at the antrum. The opinions of the audience for these six minor topics were expressed by an electronic voting system, as was conducted in 2008. It was good opportunity to identify a point of contact about the debates on managing gastric cancer. The results of these debates and studies will identify the best methods to treat patients with gastric cancer.
김성근 한국지방계약학회 2012 지방계약연구 Vol.3 No.1
지방계약법이 제정, 시행되면서 지방계약분쟁조정제도 역시 지방계약법과 관련하여 발생한 분쟁을 해결하는데 상당한 기여를 하고 있다고 보이나, 소위 대체적 분쟁해결수단으로서 기능을 충분히 발휘하고 있다고 보기 어렵다. 따라서 지방계약분쟁조정제도가 그 본래적 기능을 발휘하기 위해서는 현재 분쟁조정제도의 현황과 문제점을 파악한 후, 분쟁조정제도를 활성활 수 있는 제도적·절차적 장치를 마련하고, 분쟁조정제도의 내용을 심도있게 분석하여 향후 분쟁조정에 활용하도록 그 대안을 검토하여 제시하고자 한다.
김성근,김영미,염정은,진송효,채규태,이성범 대한약리학회 2009 The Korean Journal of Physiology & Pharmacology Vol.13 No.6
Rifampicin is a macrocyclic antibiotic which is used extensively for treatment against Mycobacterium tuberculosis and other mycobacterial infections. Recently, a number of studies have focused on the immune-regulatory effects of rifampicin. Therefore, we hypothesized that rifampicin may influence the TLR2 expression in LPS-activated RAW 264.7 cells. In this study, we determined that rifampicin suppresses LPS-induced TLR2 mRNA expression. The down-regulation of TLR2 expression coincided with decreased production of TNF-α. Since NF-κB is a major transcription factor that regulates genes for TLR2 and TNF-α, we examined the effect of rifampicin on the LPS-induced NF-κB activation. Rifampicin inhibited NF-κB DNA-binding activity in LPS-activated RAW 264.7 cells, while it did not affect IKKα/β activity. However, rifampicin slightly inhibited the nuclear translocation of NF-κB p65. In addition, rifampicin increased physical interaction between pregnane X receptor, a receptor for rifampicin, and NF-κB p65, suggesting pregnane X receptor interferes with NF-κB binding to DNA. Taken together, our results demonstrate that rifampicin inhibits LPS-induced TLR2 expression, at least in part, via the suppression of NF-κB DNA-binding activity in RAW 264.7 cells. Thus, the present results suggest that the rifampicin-mediated inhibition of TLR2 via the suppression of NF-κB DNA- binding activity may be a novel mechanism of the immune-suppressive effects of rifampicin.