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열린타원구멍을 통한 기이색전증이 발병 원인으로 추정되는 뇌경색 환자의 동서 협진 치험 1례
김민성,옥효준,양지연,정택수,선종주,유소정,Kim, Min-sung,Ok, Hyo-joon,Yang, Jee-yun,Jeong, Taek-su,Sun, Jong-joo,You, So-jung 대한한방내과학회 2016 大韓韓方內科學會誌 Vol.37 No.5
Objective: To evaluate the effects of integrative treatment with conventional and Korean medicine on cerebral infarction due to presumed paradoxical embolism through a patent foramen ovale. Methods: We applied acupuncture, herbal medication, western medication, and physical therapy routinely every day and applied fluid therapy provided as needed. The NIHSS, K-MBI, MRS, MMT, and MMSE-K score were determined to assess any improvement in symptoms. Results: Scores appeared to be improved for the NIHSS (9 to 5), K-MBI (94 to 100), MRS (2 to 1), MMT (2+, 4 to 4, 4), MMSE-K (24 to 26). No side effects were observed during the treatment. Conclusions: This study demonstrates that integrative treatment with conventional and Korean medicine may be an effective option for treating cerebral infarction due to a presumed paradoxical embolism through a patent foramen ovale.
김민성,정연태 한국전기전자재료학회 2009 Transactions on Electrical and Electronic Material Vol.10 No.3
This report demonstrates the immobilization of uniformly sized gold nanoparticles (AuNPs) on UV cross-linked poly(4-vinylpyridine) (P4VP) polymer thin films and the preparation of micropatterned structures of AuNPs on these films. The polymer thin films were prepared by a spin-coating of P4VP onto a cleaned silicon wafer surface. Upon UV irradiation, these films were then photo cross-linked. Gold nanoparticles were immobilized by immersing the polymer surface in a colloidal solution of gold nanoparticles stabilized by citric acid. The morphology of the films and the immobilization of AuNPs were studied by atomic force microscopy (AFM) and UV-visible spectroscopic techniques. The micropatterned gold structures that were produced on the polymer surface are delineated by combining with the photolithographic method. While untreated and simply spin coated films were physisorbed and unstable that could be easily removed by rinsing with a solvent, the cross-linked and AuNPs immobilized P4VP films were found to be highly stable even after repeated solvent extractions.
김민성,이동현,이태경 한국고분자학회 2015 Macromolecular Research Vol.23 No.8
Herein, we present a method to generate site-selective assembly of suspended silver nanowires (Ag NWs) in large area by using hydrophobic patterned surfaces of n-paraffin. A thin layer of n-paraffin (eicosane, C20H42) was prepared on the desired substrates. Then, the microcontact printing technique utilizing prism-type patterns of poly(dimethyl siloxane) (PDMS) was applied on the eicosane layer to generate hydrophobic patterns on the substrates. Ag NWs were synthesized through a polyol process with poly(vinyl pyrrolidone) (PVP) and dispersed in methanol. After Ag NWs suspension was introduced on the patterns of n-paraffin, we found that complete evaporation of the suspension solvent resulted in the selective assembly of Ag NWs in troughs of the patterns due to the synergetic effect of both surface energy difference and height contrast. Consequentially, the large-area assembly of Ag NWs was achieved on the substrates by thermally removing the eicosane patterns. Moreover, the optical and electrical properties of the Ag NWs assembly were characterized for applications as transparent electrical conductors.
半支蓮의 Bcl-2 발현감소를 통한 자궁근종세포 성장억제에 미치는 효과
김민성,한지영,김동일,이태균 대한한방부인과학회 2004 大韓韓方婦人科學會誌 Vol.17 No.4
자궁근종은 자궁근육층에 가장 흔하게 발생하는 평활근 세포의 양성 종양이다. Bcl-2 단백질은 apoptosis(細胞死)를 저해하는 유전자 산물로 다양한 세포들의 細胞死를 예방하는 것으로 알려져 있으며 사람의 평활근종 세포에서도 Bcl-2 단백질이 생성된다. 이 논문에서는 자궁근종에 대한 半支蓮의 효능을 연구하기 위하여 半支蓮이 자궁근종 세포의 Bcl-2 발현에 미치는 영향을 검정하였다. 즉 Bcl-2 유전자 형질발현을 상향 조절하는 것으로 알려진 progesterone(황체호르몬)의 무혈청배지로 배양된 평활근종세포에서 半支蓮가 Bcl-2 단백질 발현에 미치는 영향을 검토하였다. 평활근종과 자궁근육층 조직 추출물의 Western blot 결과, 평활근종 세포에는 26 kDa의 Bcl-2 단백질이 과량 발현되었으나, 자궁근육층 세포에는 발현되지 않았다. 평활근종 세포에서 Bcl-2 단백질 발현은 progesterone (100 ng/mL) 농도에 의존하였다. 그러나 첨가하는 半支蓮(20 ug/ml)의 농도증가에 따라 Bcl-2 단백질발현은 명확하게 감소하는 경향을 나타내었다. 이러한 결과들을 통해 자궁 평활근종 세포에서 progesterone은 Bcl-2 단백질을 발현을 증강시키며, 半支蓮은 자궁 평활근종 세포의 Bcl-2단백질발현을 감소시키는 활성을 나타냄을 알 수 있었다.
유한요소해석을 이용한 AA1100의 변형 불균일성에 미치는 다축 단조 유형의 영향 연구
김민성,김정균,유태현,조유연,이성,정효태,최시훈 대한금속·재료학회 2021 대한금속·재료학회지 Vol.59 No.9
The effect of 3 forging routes (Route A - 1~12 passes by plane forging (PF) and reverse-plane forging (R-PF), Route B – 1~6 passes by PF and R-PF, 7~12 passes by diagonal forging (DF) and reversediagonal forging (R-DF), Route C – 1~12 passes by DF and R-DF) on maximum load to produce the workpiece, deformation heterogeneity and hydrostatic pressure distribution in AA1100 was theoretically investigated using finite element analysis (FEA). The maximum load per pass required to complete 1 cycle of the SPD process was different depending on the forging routes. Route A was relatively higher than Route B and C. From the results of effective strain, the deformation heterogeneity was predicted at the center, edge, and corner regions of the AA1100 workpiece produced by Route A and B. However, the distribution of effective strain in Route C was relatively more homogeneous than Route A and B. The average hydrostatic pressure, which is closely related to the suppression of crack formation in the workpiece under multi-axial forging, was predicted to be relatively bigger in Route C than Route A and B.
김민성,국태용,김효신,이진수 제어·로봇·시스템학회 2017 International Journal of Control, Automation, and Vol.15 No.1
In this paper, an adaptive iterative learning controller (AILC) with input learning technique is presentedfor uncertain multi-input multi-output (MIMO) nonlinear systems in the normal form. The proposed AILC learnsthe internal parameter of the state equation as well as the input gain parameter, and also estimates the desired inputusing an input learning rule to track the whole history of command trajectory. The features of the proposed controlscheme can be briefly summarized as follows: 1) To the best of authors’ knowledge, the AILC with input learningis first developed for uncertain MIMO nonlinear systems in the normal form; 2) The convergence of learninginput error is ensured; 3) The input learning rule is simple; therefore, it can be easily implemented in industrialapplications. With the proposed AILC scheme, the tracking error and desired input error converge to zero as therepetition of the learning operation increases. Single-link and two-link manipulators are presented as simulationexamples to confirm the feasibility and performance of the proposed AILC.