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권도익 ( Do Ik Kwon ),정순문 ( Sun Mun Jeong ),정장환 ( Jang Hwan Jung ),성설화 ( Seol Hwa Seong ),김준희 ( Joon Hee Kim ),박종빈 ( Jong Bin Park ),전영승 ( Young Seung Jeon ),서기석 ( Kee Suck Suh ),장민수 ( Min Soo Jang ) 대한피부과학회 2022 대한피부과학회지 Vol.60 No.5
Background: Lichenoid drug eruption (LDE) is a relatively rare form of cutaneous drug eruption and that resembles lichen planus on a clinical and histological basis. Although there are some studies on histopathological findings of LDE, studies on clinical findings of LDE are limited. Objective: To investigate the clinical and histopathologic findings and prognosis of LDE. Methods: We retrospectively investigated the clinicopathologic findings of LDE patients who visited Kosin University Gospel Hospital between 1990 and 2020. Results: This study included 44 LDE patients (male:female=1.4:1). The most common causative drug was anti-tuberculous drugs (52.3%), followed by 5-fluorouracil (11.4%), and captopril (9.1%). There were pruritic erythematous scaly or lichenoid patches and plaques in all cases. The most frequently involved sites were trunk and extremities. Notably, 15 cases (34.1%) involving the scalp and 3 cases (6.8%) involving the oral mucosa. Treatment modalities included oral, topical corticosteroid, and oral antihistamines. Among 44 cases, 28 patients discontinued the causative agent, and 16 patients continued to use it after diagnosis of LDE. The mean duration of treatment for patients who discontinued or did not discontinue the causative drugs was 4, 10 weeks, respectively. The most commonly observed histopathologic findings were superficial and deep perivascular infiltration of inflammatory cells (100.0%) and eosinophil infiltration (93.2%). Conclusion: LDE can be differentiated from idiopathic lichen planus by clinicopathologic findings. LDE appears to be a mild form of drug eruption in which symptoms can be controlled with conservative treatment, even without the cessation of causative drugs for the treatment of the underlying disease. (Korean J Dermatol 2022;60(5):275∼283)
Dermoscopic features of an unusual case of targetoid hemosiderotic nevus
정순문,정장환,권도익,성설화,장지윤,박종빈,장민수 고신대학교(의대) 고신대학교 의과대학 학술지 2023 고신대학교 의과대학 학술지 Vol.38 No.3
Targetoid hemosiderotic nevus (THN) is a rare variant of melanocytic nevus, characterized by a sudden development of a targetoid ecchymotic halo around a pre-existing nevus. THN clinically raises concern for malignant transformation due to its abrupt change in color and size. THN should be distinguished from other diseases showing a peripheral halo, including targetoid hemosiderotic hemangioma, halo nevus, and Meyerson nevus. Dermoscopy can help clinicians to differentiate THN from these diseases. The typical dermoscopic features of THN are known to be divided into two distinctive areas: the central melanocytic area and the peripheral ecchymotic area. In our case, dermoscopy revealed a novel bull’s eye pattern composed of a central area with characteristic features of benign melanocytic nevus, an intermediated white circular ring, and a peripheral milky red area. When a sudden change occurs in a pre-existing nodule showing targetoid features, dermoscopy should be considered before conducting a biopsy or surgical intervention.
정호준,장영철,권도익,안종필,Jung, Ho-Joon,Chang, Young-Chul,Kwon, Do-Ick,Ahn, Jong-Pil 대한한방내과학회 2000 大韓韓方內科學會誌 Vol.21 No.5
A clinical study was carried out 1 case of ischemic cerebrovascular accident which occurred at puerperium in a 27 year-old woman followed by vaginal delivery The results were as follows: 1. In the clinical view, it was thought that the cause of this case is intracranial venous thrombus, because the symptom-headache, foaming at the mouse, acromyotonia, hemiparesis- occurred in the postpartum and functional outcome is good. 2. In this case, the patient's functional system of spleen-stomach is usually weak, and due to delivery the functional system of spleen-stomach is more insufficient. so it can not control damp-phlegm(濕痰). In addition, vital energy of liver stagnate.
김경석,이상룡,김재훈,권도익,Kim, Kyung-sok,Lee, Sang-yong,Kim, Jae-hoon,Kwon, Do-ick 사상체질의학회 2001 사상체질의학회지 Vol.13 No.3
The irritable bowel syndrome(IBS) is the most common gastrointestinal disorder in clinical practice and is characterized by abdominal pain associated with a chronic disturbance of defecation. It is important to discriminate IBS from organic bowel disease. Based on clinical and epidemiologic studies, specific symptom criteria for IBS have been developed. The subject is a 29 year old man who has abdominal pain, chronic diarrhea, general weakness, dizziness, insomnia and has been diagnosed as irritable bowel syndrome. We classified this as Shaoyangin Mangyin(少陽人 亡陰證) and prescribed Hyeongbangjiwhangtang(荊防地黃湯) in accordance with the principle of pyoeumganggi(表陰降氣). In the result, we had the improvement of his symptoms.
폐렴 양방 치료 종료 후 지속되는 가래 및 연하장애를 주소로 하는 노인 환자의 시박탕(柴朴湯) 치험례
임보라,박영화,조준호,권도익,Lim, Bo-ra,Park, Young-hwa,Cho, Jun-ho,Kwon, Do-ick 대한한방내과학회 2017 大韓韓方內科學會誌 Vol.38 No.5
Objectives: We conducted this study to report the clinical effects of Sibak-tang (Saiboku-to) in an elderly patient suffering from sputum and dysphagia after conventional treatment for pneumonia. Methods: The Sibak-tang was administered to the patient to treat sputum and dysphagia. The results were assessed by measuring the frequency of the sputum and conducting a videofluoroscopic swallowing study. Results: After about three weeks of herbal medicine treatments, the patient's symptoms of respiratory problems improved. The results of the videofluoroscopic swallowing study were also improved. Conclusion: Sibak-tang could be an effective treatment for elderly patients suffering from sputum and dysphagia after conventional treatment for pneumonia.
스트레스에의한 여성 울증(鬱證) 환자의 가미소요산(加味逍遙散) 치험 3례
강병철,성경화,송일헌,김의철,권도익,박경훈,정성민,박준하,고은상,Kang, Byung-Chul,Sung, Kyoung-Hwa,Song, Il-Hun,Kim, Ui-Chul,Kwon, Do-Ik,Park, Kyung-Hoon,Jung, Sung-Min,Park, Jun-Ha,Ko, Eun-Sang 대한한방내과학회 2004 大韓韓方內科學會誌 Vol.25 No.3
UL-syndrome(鬱證) is a syndrome of emotional depression and various physical symptoms generally due to chronic psychological stress, without constitutional abnormality. These are cases of female patients suffering from headache, chest discomfort, heart burning, insomnia, dyspepsia, anorexia, fatigue and some other minor symptoms due to chronic stress. We diagnosed these cases as UL-syndrome and treated them with oriental medicine, specifically Gamisoyosan(加味逍遙散). This paper describes the symptoms that the patients suffered, the treatment used, and identifies stages in the development of UL-syndrome, and suggests a stage in which Gamisoyosan is efficacious.
박영화,임보라,전경륭,권도익,Park, Young-Hwa,Lim, Bo-Ra,Jeon, Gyeong-Ryung,Kwon, Do-Ick 대한중풍순환신경학회 2017 대한중풍.순환신경학회지 Vol.18 No.1
■ Objectives Atrial fibrillation is the most common cause of cardioembolic stroke. Of the 44 ischemic stroke patients with atrial fibrillation who were hospitalized in hospital of Korean Medicine from July 1, 2014 to June 30, 2017, we selected 39 patients who have had Magnetic Resonance Angiography. We divided them into Atrial Fibrillation group with no stenosis or less than 50% stenosis in the ipsilateral artery of the lesion and Artery to Artery Embolism group with more than 50% stenosis or occlusion in the ipsilateral artery of the lesion. ■ Methods Clinical characteristics, examination and evaluation tools were collected from the patient's electronic medical records. CHADS2, Initial National Institutes of Health Stroke Scale, 8-item Stroke Scale and Improved 8-item Stroke Scale Number were checked. ■ Results & Atrial Fibrillation group showed differences in age, brain lesion location, vascular lesion, Conclusion initial National Institutes of Health Stroke Scale, initial 8-item Stroke Scale and progress compared to Artery to Artery Embolism group.