흡입마취시 Neostigmine 과 Pyridostigmine 이 심혈관 반응에 미치는 영향

강효석,이춘희,이귀용 대한마취과학회 1990 Korean Journal of Anesthesiology Vol.23 No.6

At the end of the operation, residual neuromusular blookade may be antagonized by anticholines-terase (edrophonium, neostigmine and pyridostigmine). Neostigmine is probably commonly used antagonist of nondepolarizing neuromuscular blocking agents. But, because of an apparent longer duration of action and lesser muscarinic effects, pyridos- tigmine has been suggested as possibly superior to neostigmine as an antagonist of nondepolarizing neuromuscular blockade. Accordingly, present study observed the heart rate, systolic and diastolic blood pressure changes following equipotent doses of pyridostigmine and neostigmine given with glycopyrrolate in inhalation anesthesia (halothane and enflurane). Eighty patients were randomly divided in four groups as follows: Group I: halothane, glycopyrrolate + neostigmine Group II: halothane, glycopyrrolate + pyridostigmine Group IIl: enflurane, glycopyrrolate + neostigmine Group IV: enflurane, glycopyrrolate +pyridostigmine The results were as follows: 1) In halothane and enflurane anesthesia, the changes in heart rate were significant in each group after 4 minutes and especially, the group I, III showed more decrease than the group II, IV. 2) Tachycardia were observd until 6 minutes after administration of anticholinesterase in each group. Bradycardia were appeared at 6 minutes in the group I, IIl and at 14 minutes in the group II, IV and, each group showed bradycardia which continued over 20 mintes. 3) Even though the decrease of systolic and diastolic blood pressure showed transiently with time, there were no significant difference in the changes in ach group. 4) When the same anticholinesterase was administered, the cardiovascular responses were no significant difference between the halothane and enfurane anesthesia. In conclusion, pyridostigmine with glycopyrrolate seems to produce minimal changes in the cadiovascular responses in halothane and enflurane anesthesia.

IPO기업의 장기성과에 관한 연구 - 소유구조와의 관련성을 중심으로 -

강효석,박남희 한국재무학회 2007 한국재무학회 학술대회 Vol.2007 No.05

투자성과지표로서 EVA의 유용성에 관한 실증연구

강효석,남명수,Kang, Hyo-Seok,Nam, Myeong-Su 한국재무관리학회 1997 財務管理硏究 Vol.14 No.3

본 연구는 가치창조 경영의 중심지표인 EVA가 우리나라에서도 올바른 주주가치 평가지표로서 활용될 수 있을지를 살펴보고 있다. 실증분석 결과를 보면 연구기간(1986년${\sim}$1995년)중 대부분의 기업은 주당 EVA가 음(陰)이였고, 주당 EVA는 주당영업 이익, 주당순이익, 자기자본이익률등 기존 성과 척도들에 비해 주가와 상관관계가 가장 높았다. 연도별 EVA를 기준으로 매년 포트폴리오를 재구성하는 방법으로 10년간의 초과 수익률을 계산한 결과 EVA가 양(陽)인 포트폴리오는 음(陰)경우보다 초과수익률이 거의 140%정도 높았다. 또한 당해연도 뿐 아니라 전년도 주당 EVA가 주가변동의 주요결정 요인인것도 발견되었다. 이러한 연구결과는 EVA의 극대화가 주가의 극대화 곧 기업가치 및 주주가치 극대화를 의미하므로 성과지표로서 EVA를 성과측정 및 보상등 기업의 모든 의사결정에 활용할 수 있다는 것을 시사해 준다. 또한 EVA를 포트폴리오 관리를 위한 새로운 투자지표로 활용한다면 증권시장에서 수익률을 재고할 수 있다는 것을 입증해줌으로써 증권시장의 활성화에 크게 기여할 수 있을 것이다.

제왕절개술을 위한 부위마취

강효석 대한마취통증의학회 2008 Anesthesia and pain medicine Vol.3 No.1

During the last 2 decades, there has been an increasing impetus to avoid general anesthesia in women undergoing cesarean delivery because of the increased of failed endotracheal intubation in pregnant women compared with nongravid patients. The past decade has seen major changes in the practice of obstetric anesthesiology, as evidenced by an improved understanding by anesthesiologists of many disease entities seen in obstetric patients, as well as by the enhancements of new techniques and drugs. Recent advances in the practice of this specialty include the refinement of the combined spinal-epidural technique for both labor analgesia and cesarean delivery, the use of continuous infusions of dilute solution of local anesthetics combined with opioids, the development of multiorifice epidural catheters, the dramatic increase in the use of subarachnoid anesthesia for elective cesarean delivery, and the introduction of new amide local anesthetics. Because of the tremendous increase in the application of neuraxial techniques, the administration of general anesthesia for cesarean delivery has dramatically decreased. Also the number of deaths associated with regional anesthesia declined markedly with the withdrawal of 0.75% bupivacaine and probably due to increasing awareness of local anesthetic toxicity and increased use of test dosing. The discussion includes new methods and drugs associated with regional anesthesia for cesarean delivery and highlight their benefits and risks.

자궁경 자궁내막절제술 후 발생한 뇌교외수초용해증의 완전 회복

강효석,오인영,김영주,조춘규,이수경,양신영,권용임,최환영,양윤석 대한마취통증의학회 2006 Korean Journal of Anesthesiology Vol.50 No.1

Transcervical resection of endometrium is under-utilized in the treatment of dysfunctional uterine bleeding, uterine myoma and menorrhagia. The procedure is similar to transurethral resection of prostate in men with a possibility of substantial absorption of irrigation fluid. Absorption of a large volume of fluid can cause excessive intravascular volume, hyponatremia, cerebral edema and death. Severe hyponatremia leading to extrapontine myelinolysis is an extremely rare complication of this procedure. So, We report a case of developed extrapontine myelinolysis after hysteroscopic myomectomy which, however, showed complete recovery. (Korean J Anesthesiol 2006; 50: 94~8)

기업분할 정보가 주주의 부에 미치는 영향

강효석,서재웅 한국외국어대학교 지식출판콘텐츠원 글로벌경영연구소 2011 글로벌경영연구 = Journal of global business research Vol.23 No.3

This paper investigates the effects of divestitures announcements on shareholder wealth. Analyzing a sample of 208 divestitures during 1999~2008, we find that ordinary divestitures earn significant positive CARs than divestitures subsequent to backdoor listings. Divestitures to become holding companies have significantly higher CARs than divestitures with different purposes. It is also evidenced the abnormal announcement returns of focusing-divestitures higher than those of non-focusing divestitures. However, we could not support the hypothesis that the announcement effects of spin-offs are different from those of non spin-offs.

Optimal dose of remifentanil for the prevention of hemodynamic responses during induction of anesthesia with desflurane

강효석,박혜진,백승민,김선오 대한마취통증의학회 2015 Anesthesia and pain medicine Vol.10 No.2

Background: This study was designed to determine the optimal dose of remifentanil single bolus for the prevention of cardiovascular disturbance due to both a rapid increase in desflurane concentration and stimulation by intubation. Methods: One hundred three adult patients were enrolled in this prospective, double-blind, randomized study. Before anesthesia induction, all patients received normal saline (control) or one of the following 3 doses of remifentanil: 1.0 μg/kg of remifentanil (remifentanil 1.0), 1.5 μg/kg of remifentanil (remifentanil 1.5), and 2.0 μg/kg of remifentanil (remifentanil 2.0). After induction with propofol and rocuronium, 1.3 minimal alveolar concentration of desflurane with oxygen was administered via a face mask. Heart rate (HR) and mean blood pressure (MBP) were recorded before remifentanil administration, and 1, 2, and 3 min after inhalation of desflurane, as well as 0, 1, 2, and 3 min after intubation. The proportions of patients with hemodynamics that maintained within ± 25% of preinduction values (MBP and HR proportion) were calculated. Results: MBP and HR were lower in the 3 remifentanil groups than in the control group throughout the study period. The MBP proportion was higher in remifentanil 1.0 group than in control group. The HR proportion was higher in the 3 remifentanil groups than in control group. Conclusions: A single bolus injection of remifentanil (1.0–2.0 μg/kg) may be effective in alleviating adverse hemodynamic changes induced by both desflurane inhalation and tracheal intubation. Especially, administration of remifentanil 1.0 μg/kg maintained more stable blood pressure compared to the control group throughout the study period.

위험가중 자본규제의 도입이 은행주가에 미친 영향

姜孝錫 韓國外國語大學校 經濟經營硏究所 1995 經濟經營硏究 Vol.14 No.1

기업합병·매수의 동기에 관한 연구

姜孝錫 한국외국어대학교 1994 한국외국어대학교 논문집 Vol.27 No.2

R. Brealey and S. Myers, Principles of corporate finance

姜孝錫 韓國外國語大學校 經濟經營硏究所 1986 經濟經營硏究 Vol.5 No.1