비정상 자궁경부세포검사 대처 및 전암성 병변의 치료

민경진 대한산부인과학회 2023 연수강좌 Vol.68 No.0

물산업 해외시장 진출 활성화 방안 - Water Partnership 구축을 중심으로 -

민경진,김동환,조은채,Min, Gyeong-Jin,Kim, Dong-Hwan,Jo, Eun-Chae 한국수자원학회 2011 물과 미래(한국수자원학회지) Vol.44 No.8

Two cases of Chronic Intestinal Pseudo-obstruction treated by jejunostomy

민경진,이상훈 대한내과학회 2021 대한내과학회 추계학술대회 Vol.2021 No.1

Risk Ranger를 활용한 잠재적 위해식품과 미생물 조합에 대한 위해순위 결정

민경진,윤기선,황인균,이순호,조준일 한국식품위생안전성학회 2011 한국식품위생안전성학회지 Vol.26 No.2

Risk ranking must be determined for various hazards/food combinations to conduct microbial risk management effectively. Risk Ranger is a simple, easy-to-use calculation tool developed in Microsoft Excel and designed to rank the risk (low, medium, and high) for semi-quantitative microbial risk assessment. The user is required to answer 11 questions in Risk Ranger related to 1) severity of the hazard, 2) likelihood of a disease-causing dose of the hazard being present in the meal, and 3) the probability of exposure to the hazard in a defined time. This study determined the risk ranking for twenty three combinations of foodborne pathogens/potentially hazardous foods (PHFs) using a Risk Ranger. In this study, pathogenic E. coli in fresh cut produce salad was scored as 79, which was the highest rank among the 23 combinations of the foodborne pathogens and PHFs. On the other hand, zero risk was obtained with V. parahaemolyticus in sushi, Salmonella in meat products and E. coli O157:H7 in hamburger patties. Although Risk Ranger is very simple method to rate the risk of foodborne pathogens and PHFs combination, the accuracy of result was mainly affected by the availability and accuracy of data in the literature. According to the result of literature review, the data are needed for contamination rate of raw materials, consumption amount/frequency of PHFs, and the effect of processing on pathogen. Risk ranking must be continuously revalidated with new data.

Carbofuran과 Chiorothalonil의 공존이 Brachydanio rerio(zebrafish)를 이용한 단기간 생물농축계수의 측정에 미치는 영향

민경진,차춘근 한국환경보건학회 1997 한국환경보건학회지 Vol.23 No.2

This study was performed to investigate the effect of co-existence of carbofuran and chlorothalonil on the short-term bioconcentration factor in Brachydanio rerio(zebrafish). The fishes were exposed to the single and combined treatment of carbofuran and chlorothalonil for 1, 3 and 5 days. Experimental concentrations of carbofuran were 0.05 and 0.10 ppm under the single treatment. And those of chlorothalonil were 0.005 and 0.010 ppm. Experimental concentrations of the combined treatment of carbofuran and chlorothalonil were 0.05 ppm+0.005 ppm, 0.05 ppm+0.010 ppm, 0.10 ppm+0.005 ppm for 1, 3 and 5 days, respectively. Carbofuran and chlorothalonil in fish and in test water were extracted with n-hexane and acetonitrile. GC-ECD was used to detect and quantitate carbofuran and chlorothalonil. 1-day, 3-day and 5-day bioconcentration factors(BCF$_1$, BCF$_3$ and BCF$_5$) of each pesticide were obtained from the quantitation results. The depuration rate of each pesticide was determined over the 24-h period after combined treatment. The results were as follows: Carbofuran did not bioaccumulate in zebrafish under the single and combined treatment for testing periods. BCF$_1$ values of chlorothalonil in concentration of 0.005 and 0.010 ppm under the single treatment were 0.508, 0.621, BCF$_3$ were 1.327, 1.511 and BCF$_5$ were 1.331, 1.597, respectively. BCF$_1$ values of chlorothalonil were 0.512, 0.520 and 0.619, respectively, when the concentration of carbofuran and chlorothalonil in combined treatment were 0.05+0.005, 0.05+0.010 and 0.10+0.005 ppm. BCF$_3$ values of chlorothalonil 1.341, 1.338 and 1.513, respectively, and BCF$_5$ values of chlorothalonil were 1.332, 1.327 and 1.521, respectively, under the above combined treatment. Depuration rate constants of chlorothalonil in concentration of 0.005 and 0.010 ppm under the single treatment were 0.011 and 0.012. Depuration rate constants of chlorothalonil were 0.011, 0.010 and 0.011, when the concentration of carbofuran and chlorothalonil in combined treatment were 0.05+0.005, 0.05+0.010 and 0.10+0.005 ppm. It was observed that no significant difference of carbofuran and chlorothalonil concentration in fish extracts, test water, BCFs and depuration rate constants of carbofuran and chlorothalonil between combined treatment and single treatment. It was considered that no appreciable interaction at experimental concentrations due to lower concentrations than LC$_{50}$. It is suggested that the difference of BCFs between carbofuran and chlorothalonil due to those of fat composition of fish and solubility of carbofuran and chlorothaionil.

휴 윌리암슨의 에스라-느헤미야 편집가설 재고

민경진 장로회신학대학교 기독교사상과 문화연구원 2010 장신논단 Vol.38 No.-

대기업과 중소기업 시판 된장의 이화학적 특성과 항산화 활성 및 소비자 기호도 분석

민경진,곽은정,변재영,최일숙 한국식품조리과학회 2018 한국식품조리과학회지 Vol.34 No.6

Purpose: This study examined a quality evaluation by the physicochemical characteristics, antioxidant properties, and sensory acceptance test with a commercial Doenjang product using three large corporations (BCW, BHC, BHP) and five small businesses (MFN, MSC, MSN, MYG, MJM). Methods: The water content, pH, salt, reducing sugar, color value, texture profiles, total polyphenols contents and total flavonoids with antioxidant activities, as well as the consumer acceptance test of 8 Doenjang products were evaluated. Results: Commercial Doenjang products of large corporates (BCW, BHC, BHP) had relatively narrow ranges of crude ash (11.60 to 11.97%), pH (5.20 to 5.35), saltiness (11.28 to 11.44%), and reducing sugar (13.20 to 15.81 mg/100 g), whereas Doenjang products of medium-sized companies (MFN, MSC, MSN, MYG, MJM) showed a broader range of values. The total polyphenol contents of MFN Doenjang were higher than those of the other Doenjangs and were in the following order: BCW Doenjang > MSN Doenjang > BHP Doenjang > MJM Doenjang > MSC Doenjang > MYG Doenjang > BHC Doenjang. The antioxidant activity assays also showed that Doenjangs of BCW, BHP, MFN, and MSN had high antioxidant activity exceeding those of the other Doenjangs. In the consumer acceptance test, BCW had the highest overall, color, taste, roasted flavor, after-taste likeness, and purchase intent compared to those of other Doenjangs, whereas MFN had the lowest values, even though MFN had the highest antioxidant properties. Conclusion: BCW Doenjang had the highest antioxidant properties and consumer acceptance test, but MFN Doenjang had the lowest values in consumer acceptance even though MFN had the highest antioxidant properties. Therefore, MFN Doenjang might benefit from redeveloping the product to satisfy the consumer acceptance and purchase intent.

Flexible PCB용 무전해 도금 Ni 박막/Polyimide 계면파괴에너지 평가

민경진,박성철,이지정,이규환,이건환,박영배,Min, Kyoung-Jin,Park, Sung-Cheol,Lee, Jee-Jeong,Lee, Kyu-Hwan,Lee, Gun-Hwan,Park, Young-Bae 한국마이크로전자및패키징학회 2007 마이크로전자 및 패키징학회지 Vol.14 No.1

폴리이미드 표면에 대한 습식 개질 전처리 조건에 따른 폴리이미드와 무전해 도금 Ni 박막사이의 계면파괴에너지를 $180^{\circ}$ 필 테스트를 통해 정량적으로 구하였다. KOH 처리시간이 1분인 경우 계면파괴에너지는 24.5 g/mm에서 5분 처리 시 33.3g/mm로 증가하였고, EDA처리 시간이 1분인 경우 31.6 g/mm에서, 5분 처리 시 22.3g/mm로 저하되었다. 이러한 습식 개질전처리 조건에 따른 폴리이미드 표면 거칠기 변화는 매우 작아서, 기계적 고착 효과는 계면파괴에너지 변화에 기여하지 못했음을 알 수 있다. KOH는 carboxyl기, EDA는 amine기를 폴리이미드 표면에 형성시켜 Ni과 강한 화학적 결합을 이루어, 폴리이미드 내부의 cohesive 박리거동을 보였다. 습식 개질전처리 조건에 따른 계면파괴에너지의 거동은 파면 부근에 형성된 O=C-O 결합과 매우 밀접한 연관성이 있는 것으로 판단된다. It is investigated how KOH and Rthylenediamine(EDA) treatment conditions on Polyimide film surface affect the interfacial fracture energy between electroless plated Ni and Polyimide film by $180^{\circ}$ peel test. Estimated values of interfacial fracture energy were 24.5 g/mm and 33.3 g/mm for the KOH treatment times under 1 and 5 minutes, respectively, while, those were 31.6 g/mm and 22.3 g/mm for EDA treatment times under 1 and 5 minutes, respectively. Interfacial bonding between electroless plated Ni and Polyimide seems to be dominated by chemical bonding effect rather than mechanical interlocking effect. It is found that chemical treatment produces carboxyl and mine functional groups which are closely related the interfacial bonding mechanism. Finally, it is speculated that interfacial fracture energy seems to be controlled by O=C-O bonding near cohesive failure region.

Erratum: Moderate to Severe Left Ventricular Ejection Fraction Related to Short-term Mortality of Patients with Post-cardiac Arrest Syndrome after Out-of-Hospital Cardiac Arrest

민경진,김진주,황인철,우재혁,임용수,양혁준,이근 대한중환자의학회 2017 Acute and Critical Care Vol.32 No.1

Comparison of the Seeplex HPV4A ACE and the Cervista HPV assays for the detection of HPV in hybrid capture 2 positive media

민경진,소경아,이지은,홍혜리,홍진화,이재관,김애리 대한부인종양학회 2012 Journal of Gynecologic Oncology Vol.23 No.1

Objective: To validate the efficacy of Seeplex HPV4A ACE for the detection of high-risk (HR) human papillomavirus (HPV) and HPV 16 and/or HPV 18 genotypes as compared to the PCR method and the Cervista HPV assays in cervical swab samples. Methods: Besides liquid-based cytology, additional 97 cervical swab samples were collected for HPV genotyping by HPV4A ACE, Cervista HPV assays, and PCR method. To check the statistical differences, we also conducted the paired proportion test, Cohen’s κ statistic, and a receiver operating characteristic curve. Results: Seeplex HPV4A ACE and the Cervista HPV HR showed substantial agreement with PCR for detection of HR HPVs (88.3%, κ=0.767 and 81.7%, κ=0.636, respectively). Seeplex HPV4A ACE also showed substantial agreement with the Cervista HPV 16/18 test (89.5%, κ=0.628). Additionally, the sensitivity and specificity of Seeplex HPV4A ACE and Cervista HPV HR were 91.4% vs. 84.5% and 73.4%, vs. 72.7%, respectively, when those higher than low-grade squamous intraepithelial lesions were regarded as abnormalities. HPV genotyping for HPV 16/18 detected cervical intraepithelial neoplasias (CINs) better than HR HPV tests (66.7% vs. 24.6% by HPV4A ACE, 52.6% vs. 25.9% by Cervista HPV assays in CIN II or more, relatively). Conclusion: Seeplex HPV4A ACE is an effective method as the PCR and the Cervista HPV assays for the detection of HR HPVs and for genotyping of HPV 16 and 18. Objective: To validate the efficacy of Seeplex HPV4A ACE for the detection of high-risk (HR) human papillomavirus (HPV) and HPV 16 and/or HPV 18 genotypes as compared to the PCR method and the Cervista HPV assays in cervical swab samples. Methods: Besides liquid-based cytology, additional 97 cervical swab samples were collected for HPV genotyping by HPV4A ACE, Cervista HPV assays, and PCR method. To check the statistical differences, we also conducted the paired proportion test, Cohen’s κ statistic, and a receiver operating characteristic curve. Results: Seeplex HPV4A ACE and the Cervista HPV HR showed substantial agreement with PCR for detection of HR HPVs (88.3%, κ=0.767 and 81.7%, κ=0.636, respectively). Seeplex HPV4A ACE also showed substantial agreement with the Cervista HPV 16/18 test (89.5%, κ=0.628). Additionally, the sensitivity and specificity of Seeplex HPV4A ACE and Cervista HPV HR were 91.4% vs. 84.5% and 73.4%, vs. 72.7%, respectively, when those higher than low-grade squamous intraepithelial lesions were regarded as abnormalities. HPV genotyping for HPV 16/18 detected cervical intraepithelial neoplasias (CINs) better than HR HPV tests (66.7% vs. 24.6% by HPV4A ACE, 52.6% vs. 25.9% by Cervista HPV assays in CIN II or more, relatively). Conclusion: Seeplex HPV4A ACE is an effective method as the PCR and the Cervista HPV assays for the detection of HR HPVs and for genotyping of HPV 16 and 18.