만성 호중구성 백혈병 1례

기장도,박치영,류보열,김태종,모성환,곽재정,문철호,박근홍,박유환,정춘해 朝鮮大學校 附設 醫學硏究所 1996 The Medical Journal of Chosun University Vol.21 No.1

Chronic neutrophilic leukemia is a very rare myeloproliferative disorder which is characterized by severe sustained mature neutrophilic leukocytosis in peripheral blood (PB), hepatosplenomegaly, elevated leukocyte alkaline phosphatase, serum uric acid. serun viatmin B 12 and the bleeding tendency despite normal platelet count and coagulation time, absence of philadelphia chromosome, and the absence of fever or underlying infection or disease sufficient to mimic a leukemoid reaction. We have experienced a 34-years-old male patient with atypical chronic neutrophilic leukemia. On admission, the leukocyte count was 56,860/uL. severe neutrophic leukocytosis with 76% neutrophils and rare immature forms on PB smear. Many neutrophils had toxic granules, and vacuoloes. Leukocyte alkaline phosphatase score was decreased. The cytogenetic study showed Philadelphia chromosome negative with normal karyotype.

Rieger syndrome : 증례보고 A CASE REPORT

이홍모,김정욱,장기택,이상훈,한세현,김종철 大韓小兒齒科學會 2003 大韓小兒齒科學會誌 Vol.30 No.4

Rieger syndrome은 눈의 전안방 기형과 치아결손을 특징으로 하는 희귀한 유전질환으로 두 개안면 이상과 체성기형을 동반하기도 한다. Rieger syndrome은 상염색체 우선유전(autosomal dominant inheritance)되며, 발생빈도는 약 200,000분의 1이고, Paired-like homeodomain transcription factor2(PITX2)의 변이가 이 질환과 연관이 있는 것으로 보고되고 있다. 본 증례는 Rieger syndrome으로 진단 받은 4세 7개월 된 여아에 대한 것으로, 양안에 다동공증과 후태생환을 보이고, 측모두부계측에서 상악골 열성장이 나타났으며, 상악유측절치와 더불어 다수의 영구치 결손이 방사선 상에서 관찰되었다. 이 증례를 통하여 Rieger syndrome 환아의 구강 및 두 개안면의 소견을 관찰하고, 관련 문헌을 고찰하여 다소의 지견을 얻었기에 보고하는 바이다. Rieger syndrome is a rare, autosomal dominant gentic disorder characterized by malformation of the anterior chamber of the eye(goniodysgenesis) coincident with hypodontia. It may also be accompanied by a spectrum of dental, craniofacial and somatic anomalies. Mutations in paired-like homeodomain transcription factor2(PITX2) are associated with the syndrome, and its frequency in the general population has been estimated to be 1 : 200.000. In the present case, the patient, 4 year 7 month-old female, had posterior embryotoxon and polycoria. The maxilla was retrusive in cephalometric radiography. She had congenital missing on #52, #62 and some tooth germs of permanent tooth were not detected in panoramic radiography. The purpose of this paper is to report the dental and craniofacial findings and review the pertinent literature through this case.

한의진단명과 진단요건의 표준화 연구 II (표준화 실례) : 2차년도 연구결과 중간 보고

양기상,최선미,최승훈,안규석,박경모,박종현,김성우,신승호,정우열,전병훈,고현,김정범,신상우,김성훈,김동희,권영규,엄현섭,장혜옥 한국한의학연구원 1996 한국한의학연구원논문집 Vol.2 No.1

The diagnostic requirements were suggested and explained regarding the systems of differentiation of symptoms and signs in the second year study of standardization and unification of the terms and conditions used for diagnosis in oriental medicine. The systems were as follows; - differential diagnosis according to condition of body fluid, differentiation of syndromes according to the state of qi and blood, differential diagnosis according to relative excessiveness or deficiency of yin and yang(氣血陰陽津液辨證) - differentiation of diseases according to pathological changes of the viscera and their interrelation - analyzing and differentiating of febrile diseases in accordance with the theory of the six channels(傷寒辨證) The individual diagnosis pattern was arranged by the diagnostic requirements in the following order : another name(異名), notion of diagnosis pattern, index of differentiation of symptoms and signs(辨證指標), the main point of diagnosis, analysis of diagnosis pattern(證候分析), discrimination of diagnosis pattern(證候鑑別), a way of curing a diseases(治法), prescription(處方), herb in common use(常用藥物), diseases appearing the diagnosis pattern(常見疾病), documents(文獻調査). This study was carried out on the basis of the Chinese documents and references.

다발성 골수종으로 이행한 단일형질세포종 1예

정재용,모성환,기장도,문철호,김창욱,전용준,박유환,정춘해,오윤경 조선의대 1995 The Medical Journal of Chosun University Vol.20 No.2

과도한 운동으로 발생한 횡문근융해증에 의한 급성신부전증 1예

문철호,류보열,모성환,김태종,기장도,박용관,김용환,정종훈 조선대학교 1995 The Medical Journal of Chosun University Vol.20 No.1

Rhabdomyolysis may be defined as a clinical and laboratory syndrome which releases muscle cell contents into the plasma, such as creatine phosphokinase, due to skeletal muscle injuries. It can be the result of many diverse causes including muscle disease, ischemia, genetic disorder, metabolic disorder, infectious disease, drugs, comatose state, trauma or vigorous exercise that can lead to acute renal failure as a complication. Since first reported in 1941, rhabdomyolysis-induced acute renal failure has been documented many times, and the major causes of this disease are carbon monoxide poisoning, snake bites, and etc in Korea Reports of acute renal failure after exercise-related rhabdomyolysis with myoglobinemia are rare. We report a case of acute renal failure caused by exercise-related rhabdomyolysis in a 20 year old man.

광주광역시 전문계 고등학교 특성화 및 종합발전방안

나승일,정철영,김진모,안강현,한홍진,김기용,민상기,장현진 한국농업교육학회 2008 농업교육과 인적자원개발 Vol.40 No.1

이 연구의 목적은 광주광역시 전문계 고등학교의 특성화 및 종합발전방안을 수립하는데 있다. 이 연구는 ① 전문계 고등학교 관련 선행연구 분석,② 인력육성 및 특성화 방향을 설정하기 위하여 광주광역시,전라남도,우리나라의 산업여건 분석,③ 광주광역시 전문계 고등학교에 대해 Malcolm Baldrige 평가모형에 의한 진단평가와 SWOT 및 활용전략 분석, ④ 광주광역시 전문계 고등학교의 개편 요구 분석,⑤ 광주광역시 전문계 고등학교의 특성화 및 종합발전방안 설정 등의 과정을 통해 수행되었다. 이 연구의 결과는 다음과 같다. 첫째,비전은 광주광역시 전문계고 특성화와 발전 역량 구축을 통한 산업체 요구에 부합하는 우수 인력 양성이며,이를 위한 전략은 특성화 체제구축,학교교육 혁신,인적 자원 혁신,학교경영 혁신,인프라 구축으로 설정하는 것이 필요하다. 둘째, 특성화 체제 구축은 특성화 체제 개편,교육과정 중심 특성화,학과 재배치 통합형 고교 도입,특성화고 신설을 통해 추진할 수 있 는데 특히,교육과정 중심 특성화가 적극 도입되어야 한다. 셋째,학교교육 혁신은 교육과정 개편,교수 학습 개선,진로지도 개선,시설 및 기자재 개선을 통해 추진할 수 있다. 넷째,인적자원 혁신은 학교 관리자 역량 강화,교원 역량 강화,학생 역량 강화를 통해 추진할 수 있다. 다섯째,학교경영 혁신은 경영 리더십 제고,경영 성과관리 강화,학교 재정 혁신을 통해 추진할 수 있다. 여섯째,인프라 구축을 위해 지자체,대학,산업체,지역주민과 연계 강화를 통해 추진할 수 있다. 일곱째,13개 전문계 고둥학교의 여건 및 특성에 적합한 단위학교별 특성화 및 종합발전방안을 수립하였다. The purpose of this study was to suggest strategies to specialize and develop vocational high schools in Gwangju Metropolitan City. The study was orderly performed as follows: (1) reviewing literature about vocational high school, (2) analyzing the condition of industries, (3) diagnosing the vocational high school through Malcolm Baldrige model, (4) analyzing the SWOT and application strategies, (5) analyzing the needs of reform, and (6) establishing the strategies for the specialization and development of Vocational High Schools in Gwangju Metropolitan City. The major findings of this study were as the following: First, the vision was to bring up excellent human resources to corresponds industrial needs through specialization and development of vocational high schools in Gwangju Metropolitan City. Five strategies to achieve it were creating the specialization system, innovating the school education, human resources, and the school management, and building the infrastructure. Second, creating the specialization system can be performed through five tasks which were restructuring the specialization system, creating curriculum-based specialization, trading departments in inter-schools, introducing an integrated high school, and building a new specialized high school. Especially curriculum based specialization needs to be accepted. Third, innovating the school education can be performed through four tasks which were reorganizing the curriculum, improving the teaching and learning, improving the career guidance, and improving the facilities and equipments. Fourth, innovating human resources can be performed through three tasks which were enhancing each competencies of a school manager, a teacher, and a student. Fifth, innovating the school management can be performed through three tasks which were improving the management leadership, developing the performance management, and innovating the school finance. Sixth, building the infrastructure can be performed through four tasks which were enhancing the relationships with a local government, colleges, industries, and local residents. Seventh, individual strategies for the specialization and development of thirteen vocational high schools were also developed by corresponding to their conditions and characteristics.

Isolation and Structure Identification of Antibacterial Substances from the Rhizome of Zingiber mioga Roscoe

Ki Chang Jang,Seong Cheol Kim,Eun Young Song,Kong Ho Kim,Hyeog Mo Kwon,Sang Heon Kang,Ki Hun Park,Yong Hwan Jung 한국응용생명화학회 2003 Journal of Applied Biological Chemistry (J. Appl. Vol.46 No.3

Three-Dimensional Evaluation of Similarity of Right and Left Knee Joints

( Ki-mo Jang ),( Jong-hoon Park ),( Minho Chang ),( Youngjun Kim ),( Deukhee Lee ),( Sehyung Park ),( Joon Ho Wang ) 대한슬관절학회 2017 대한슬관절학회지 Vol.29 No.4

Purpose: The purpose of this study was to evaluate the anatomical similarity of three-dimensional (3D) morphometric parameters between right and left knees. Materials and Methods: Ten fresh-frozen paired cadaveric knees were tested. Following dissection, footprint areas of the anterior cruciate ligament (ACL) and posterior cruciate ligament (PCL) were measured. Surface scanning was performed using a 3D scanner. Scanned data were reproduced and morphometric parameters were measured on specialized software. After making mirror models, we compared footprint center positions of the ACL and PCL of both sides and calculated the average deviation of 3D alignment between the right-and left-side models. Results: No significant side-to-side differences were found in any morphometric parameters. Bony shapes displayed a side-to-side difference of <1 mm. Distal femoral and proximal tibial volumes did not present side-to-side differences, either; the average 3D deviations of alignment between the right and left sides were 0.8±0.4/1.1±0.6 mm (distal femur/proximal tibia). Center-to-center distances between the right and left ACL footprints were 2.6/2.7 mm (femur/tibia) for the anteromedial bundle and 2.4/2.8 mm for the posterolateral bundle. They were 1.9/1.5 mm for the anterolateral bundle and 2.2/1.8 mm for the posteromedial bundle of the PCL. Conclusions: There was a remarkable 3D morphometric similarity between right and left knees. Our results might support the concept of obtaining morphologic reference data from the uninvolved contralateral knee.

개에서 신암종 발생례

장광호 ( Kwang Ho Jang ),장환수 ( Hwan Soo Jang ),송창현 ( Chang Hyun Song ),강원모 ( Won Mo Kang ),박기대 ( Ki Dae Park ),이재현 ( Jae Hyun Lee ),장인호 ( In Ho Jang ) 한국임상수의학회 2000 한국임상수의학회지 Vol.17 No.1

체외순환 없는 관상동맥우회술시 고혈압 조절을 위한 Nicardipine 의 혈역학적 반응

김애라,김진모,장영호,김성기,박태규,전재규,신원호 대한마취과학회 2001 Korean Journal of Anesthesiology Vol.41 No.2

The Hemodynamic Response of Nicardipine for Hypertension Control during an Off-Pump Coronary Artery Bypass Graft Seong Ki Kim, M.D., Tae Kyu Park, M.D., Won Ho Sim, M.D., Young Ho Jang, M.D. Jin Mo Kim, M.D., Ae ra Kim, M.D., and Jae Kyu Cheun, M.D. Department of Anesthesiology, School of Medicine, Keimyung University, Daegu, Korea Drugs for acute blood pressure control are often required during a cardiovascular operation. Hypertension frequently occurs in an off-pump coronary artery bypass graft. The purpose of this study was to evaluate the effect of nicardipine on hemodynamic change. Twenty adult patients were studied. Anesthesia was induced intravenously with thiopental (4 mg/kg),vecuronium (1 mg/kg), and fentanyl (4 ㎲/kg), and maintained with 100% O_2 and isoflurane 1-1.5 Vol%. When systolic blood pressure rose above 150 mmHg, nicardipine 1 mg was administrated intravenously. Immediately after the nicardipine bolus injection, nicardipine was infused continuously 0.5-4 ㎲/kg/min. Thereafter, hemodynamic data was recorded. Systolic blood pressure decreased, but cardiac index significantly increased after an intravenous administration of nicardipine and was maintained during the study. There was no incidence of tachycardia. It was concluded that acute blood pressure control using nicardipine could be suitable and safe in patients with an off-pump CABG. (Korean J Anesthesiol 2001; 41: 171~177)