서울의 Penicillinase Producing Neisseria gonorrhoeae 발생빈도(1998)

김재홍,김준호,반재용,이정우,황성주,정준규,정성태,강진문,조흔정,홍창의,정혜신,이한승,김이선,이봉길,이종호,선영우,한기덕,윤성필,이성훈,안종성,박석범,문승현,조항래,김형섭,류지호,황재영,박준홍,손상욱 한양대학교 의과대학 2001 한양의대 학술지 Vol.21 No.1

In recent years, gonorrhea has been pandemic and remains one of the most common STDs in the world, especially in developing countries. For the detection of a more effective therapeutic regimen and assessing the prevalence of Penicillinase Producing Neisseria gonorrhoeae(PPNG), we have been trying to study the patients who have visited the Venereal Disease Clinic of Choong-Ku Public Health Center in Seoul since 1980 by menas of the chromogenic cephalosporin method. In 1998, 93 strians of N. genorrhoeae were isolated, among which 60(64.5%) were PPNG. The prevalence of PPNG in Seoul, which had been decreased to 39% in 1996 after a peak of 74.3% in 1993, is increased to 64.5% in 1998.

정신분열병에 대한 리스페리돈의 효과 및 안정성

이민수,김용구,김영훈,연병길,오병훈,윤도준,윤진상,이철,정희연,강병조,김광수,김동언,김명정,김상훈,김희철,나철,노승호,민경준,박기창,박두병,백기청,백인호,손봉기,손진욱,양병환,양창국,우행원,이정호,이종범,이홍식,임기영,전태연,정영조,정영철,정인과,정인원,지익성,채정호,한상익,한선호,한진희,서광윤 大韓神經精神醫學會 1998 신경정신의학 Vol.37 No.1

연구목적 : 본 시험의 목적은 임상시험 시작전에 연구자들을 대상으로 PANSS Workshop을 통하여 PANSS, ESRS에 대한 국내에서의 표준화 작업을 구축하고 새로운 정신병 치료제인 리스페리돈의 효과와 안정성을 재확인하여 리스페리돈 사용에 대한 적정화를 이루는데 있다. 연구방법 : 1996년 4월부터 1996년 9월까지 국내 39개 대학병원 정신과에 입원중인 혹은 증상이 악화되어 입원하는 정신분열병 환자 377명을 대상으로 다시설 개방 연구를 시행하였다. 1주일간의 약물 배설기간을 가진후, 리스페리돈을 8주간 투여하였고, 기준점, 1주, 2주, 4주, 그리고 8주후에 평가되었다. 용량은 제1일에는 리스페리돈 1mg씩 1일 2회, 제2일에는 2mg씩 1일 2회, 제3∼7일에는 3mg씩 1일 2회 투여하였다. 이후 환자의 임상상태에 따라 임의로 증량할 수 있으며, 최대 일일 16mg을 초과하지 않도록 하였다. 추체외로 증상을 조절하기 위한 투약을 허용하였다. 임상증상 및 부작용의 평가는 PANSS(Positive and Negative Syndrome Scale), CGI(Clinical Global Impression) 그리고 ESRS(Extrapyramidal Symptom Rating Scale)을 사용하였다. 연구결과 : 377명중 343명(91%)이 8주간의 연구를 완결하였다. 치료 종결시점인 8주후 PANSS 총점수가 20% 이상 호전된 경우를 약물 반응군으로 정의할때, 약물반응군은 81.3%였다. 리스페리돈에 반응하는 예측인자로는 발병연령, 이전의 입원 횟수, 유병기간이 관련 있었다. 리스페리돈은 1주후부터 PANSS양성, 음성, 및 일반정신병리 점수상에 유의한 호전을 보여 효과가 빨랐다. CGI의 경우도 기준점에 비해 1주후부터 유의한 감소를 나타내었다. ESRS의 경우, 파킨슨 평가점수는 기준점과 비교해 투여 1주, 2주, 4주후 유의하게 증가되었다가 8주후 기준점과 차이가 없었다. Dystonia 평가점수는 1주후만 유의한 증가를 보였으며, dyskinesia 평가점수는 유의한 차이가 없었다. 혈압, 맥박수의 생명징후 및 일반 혈액학 검사, 생화학적 검사, 심전도 검사에서 유의한 변화는 없었다. 결 론 : 이상의 다시설 개방 임상 연구를 통해 리스페리돈은 정신분열병 환자에서 양성증상뿐만 아니라 음성증상 및 전반적인 증상에도 효과적인 것으로 사료된다. 보다 명확한 평가를 위해서는 다른 항정신병약물과의 이중맹검 연구가 필요할 것으로 생각되며, 또한 장기적 치료에 대한 평가도 함께 이루어져야 하겠다. Objective : The purpose of this study was to investigate the efficacy and safety of risperidone in the treatment of Korean schizophrenic patients. Method : This multicenter open study included 377 schizophrenic patients drawn from 39 university hospitals. After a wash-out period of 1 week, the schizophrenic patients were treated with risperidone for 8 weeks and evaluated at 5 points ; at baseline, and 1, 2, 4 and 8 weeks of treatment. The dose was increased from 2mg/day(1mg twice daily) to 6mg/day(3mg twice daily) during the first week and adjusted to a maximum of 16mg/day over the next 7 weeks according to the patient's clinical response. Medication to control extrapyramidal symptoms was permitted. The psychiatric and neurological status of the patients was assessed by PANSS, CGI, and ESRS scales. Results : 343(91%) of 377 patients completed the 8-week trial period. Clinical improvement, as defined by a 20% or more reduction in total PANSS score at end point, was shown by 81.3% of patients. The predictors of response to risperidone were associated older age, shorter duration of illness, fewer previous hospitalization. Risperidone had rapid onset of action ; a significant decrease of the total PANSS and three PANSS factor(positive, negative, general), and CGI was already noticed at the end of first week. For the ESRS, parkinsonism rating scores were significantly increased until week 4 comparing with baseline. Dystonia rating scores were significantly increased until week 1, and dyskinesia rating scores were not significantly changed during the study. Laboratory parameters including vital sign, EKG, hematological, and biochemical values showed no significant changes during the trial. Conclusions : This study suggests that risperidone is generally safe and effective against both the positive and negative symptoms in our group of patients.

프랜차이즈 스포츠센터의 서비스 품질이 고객만족 및 재구매 의도에 미치는 영향

이종길,이종호,유종렬 충남대학교 체육과학연구소 2006 體育科學硏究誌 Vol.23 No.1

The franchise sports center has been most popularized among sports service industry and has worked as a pivot of life sports. These franchise sports center should have an efforts to get the competitiveness by maintaining and managing of existing customers with differentiated marketing activities. Therefore, the study of deep analysis about the relationship of service quality, customer satisfaction, re-purchasing intention and word of mouth effect would become foundation to increase service quality, maximize customer satisfaction, and maintain existing customers and eventually it would become a major factor in establishing future marketing strategies. To achieve the purpose of this study, the questionnaires was conducted on male and female adults who use franchise sports centers in Oct. 2005. For the purpose of this study, the purposive random sampling method was used and four franchise sports centers of the most biggest sports center "R" was selected. The questionnaire was distributed to 400 members of franchise sports centers and finally, 372 data have selected except for unreliable 28 data. The finally selected data was analyzed with SPSS program V.10.0. In order to examine the characteristics of sample, the frequency analysis was performed and to examine the reliability of survey tool, reliability analysis was performed. Also, to analyze basic statistic quality and verify the hypotheses of the study, t-test, one-way ANOVA and regression analysis were conducted. Through the methods mentioned above, the results drawn from the analysis are as follows; First, as a result of examining the different customers' perceptions on service quality, customer satisfaction, re-purchasing intention and effects of word of mouth by demographic factors, except for the gender, age, re-purchasing intention and effects of word of mouth, statistically significant differences were indicated on the social status and customer satisfaction. Second, as a result of examining different customers' perceptions on service quality, customer satisfaction, re-purchasing intention and effects of word of mouth by using behavior of sports center, except for customer satisfaction, re-purchasing intention and effects of word of mouth, statistically significant differences were indicated on reliability of service quality. Third, to analyze the effects of perceived service quality on customer satisfaction ,the multiple regression analysis was conducted. Among five factors in service quality, 3 factors, tangibility, empathy and responsiveness gave statistically significant effects on customer satisfaction. Forth, to analyze the effects of perceived service quality on re-purchasing intention, the multiple regression analysis was conducted. Among five factors in service quality, 2 factors, tangibility and confidentiality gave statistically significant effects on re-purchasing intention. Fifth, to analyze the effects of perceived service quality on effects of word of mouth, the multiple regression analysis was conducted. Among five factors in service quality, 3 factors, tangibility, responsiveness and confidentiality gave statistically significant effects on re-purchasing intention. Sixth, to analyze the effects of customer satisfaction on re-purchasing intention, simple regression was conducted. The customer satisfaction imposed statistically significant influence on customers' re-purchasing intention. Seventh, to analyze the effects of customer satisfaction on effects of word of mouth, simple regression was conducted. The customer satisfaction imposed statistically significant influence on effects of word of mouth. Finally, to analyze the causal relation in service quality, customer satisfaction, re-purchasing intention and word of mouth, path analysis was conducted. Service quality affected customer satisfaction, re-purchasing intention and word of mouth. Customer satisfaction as a mediator variable between service quality and post purchase behavior also affected re-purchasing intention and wold of mouth. Also, correlations between re-purchasing intention and word of mouth imposed statistically significant influence.

위절제술 환자의 표준진료지침 개발 및 적용 효과

김은희,김철규,이순교,김순덕,이혜옥,권정순,이경미,이민미,심순미,유용만,신종식,강은희,이상일,김병식,오성태,육정환,박수길 한국의료QA학회 2003 한국의료질향상학회지 Vol.10 No.2

Background : Gastric cancer is the most common malignant tumor in Korea. surgical operation is one of the major treatment modalities for gastric cancer patients. Therefore, gastrectomy is one of the most common procedures in General Surgery. There were variation in length of hospital stay and medical treatment for gastrectomy between three surgeons at Asan Medical Center. Clinical pathways have received considerable attention as a tool for recucing the medical practice variation, increasing the efficiency of care process, and improving the quality of care. The aim of this study was to evaluate the effect of a clinical pathway for gastrectomy in gastric cancer patients. Methods : The clinical pathway for gastrectomy was developed and implemented by a multidisciplinary group in Asan Medical Center. A computerized clinical pathway program was developed and revised after a pilot test. A total of 145 patients underwent gastrectomy by three surgeons at Asan Medical Center. We compared the length of hospital stay, patient satisfaction, and unplanned readmission rate between the pre-pathway group(n=67) and the post-pathway group(n=78). We also investigated the degree of satisfaction among the physicians and nurses who were main end-users of the clinical pathway. Results : The clinical pathway was applied to all target patients. The average length of hospital stay was shortened from 12.7days to 10.6days(p<0.01). The degree of patient satisfaction with the care process changed from 90.3% to 89.2% after the implementation of the clinical pathway, but the difference was of satistically significant(p=0.761). Unplanned readmission rate was 2.9% in the pre-pathway group. More than 90% of physicians and nurses answered that the clinical pathway had been a useful tool in their medical practice. Conclusions : The findings of the study demonstrated that implementation of the clinical pathway for gastrectomy produced substantial reduction in the length of hospital stay while improving the quality of patient outcomes. The computerized clinical pathway program can be used as one of the powerful patient management tools for reducing the practice variations and increasing the efficiency of care process in Korea hospital settings.

지붕경사각 변화에 따른 막구조의 풍압 변화 특성

길용식,김동우,하영철,이광렬,김종락 대한건축학회 2003 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.23 No.1(구조계)

This paper describes on the results of 1:400 geometrical laboratory modeling of wind-induced point pressure on the membrane roof structure of Stadium with variable roof slopes. The wind flow for flat ground surface was simulated in a boundary wind tunnel at Kumoh National Institute of Technology. The roof slope of membrane structure changed into 5 types. The locations of wind pressures taps are distributed on the same upper and lower part of membrane roof. The resultant wind pressure for each measurement points are analysed on 2 categories. One is acting on upper direction, the other is lower direction. The results showed that in the case of upper direction the changes of wind pressures on the membrane roof are not dominant in regard to changing roof slope, but in lower direction wind pressures are increased at the rear part of roof with changing roof slopes.

높은 지향성을 갖는 Air Line 결합기 설계

길준범,이성원,최영호,박종임,안달,박준석 호서대학교 반도체제조장비국산화연구센터 2000 학술대회 자료집 Vol.2000 No.1

본 논문에서는, 일반적인 스트립 구조의 결합기가 갖는 문제 즉, 높은 온도에서 나쁜 특성을 보이는 문제점을 극복하고자 Air Line Type의 결합기를 구현하였다. 또한 이 결합기는 24dB이상의 지향성을 가지고 있다. 해석을 위해 짝수 모드와 홀수 모드 해석법을 사용하였고, EM-Simulation으로 확인한 특성과 실제 제작된 20dB, 30dB Cellular 대역(800∼900MHz) Air Line 결합기의 결고 특성은 좋은 일치를 보여주고 있다. 또한 최대 장점인 온도 특성은 온도 데이터를 통하여 온도에 강한 특성을 보임을 알 수 있다.

地域的差異에 의한 초파리分布와 生態에 關한 硏究

李澤俊,秋鍾吉,羅燾業,姜景來 중앙대학교 기술과학연구소 1975 기술과학연구소 논문집 Vol.2 No.-

Drosophilid flies were collected by the methods of fruit trap and sweeping net from 1969 through 1975 at four different mountains of Korean panisular. 1) Eight genera including 61 species of Drosophilidae were recognized in these survey. During the period of collection, Drosophilid flies were recognized at each mountain as follows; 4 genera, 31 species and 10417 specimens at Mt. Hanla. 4 genera, 22 species and 6537 specimens at Mt. Palkong. 7 genera, 24 species and 4677 specimens at Mt. Unak. 7 genera, 53 species and 9492 specimens at Mt. Sulak. Newly recorded species of Drosophilidae from the results of these survey were as follows; 3 genera, 5 species and 275 specimens at Mt. Hanla. 3 genera, 9 species and 1220 specimens at Mt. Palkong. 7 genera, 24 species and 4677 specimens at Mt. Unak. 3 genera, 8 species and 312 specimens at Mt. Sulak. 1) Altitudinal distribution of Drosophilid flies were analysed at two areas of Mts. Sulak and Hanla. The number of flies decreased at higher altitude, and there were very scarce frequency over 1500m in altitude. However, most flies of S. graminum and D. bifasciata were collected at higher altitude in the season of mid-summer. On the contrary, some species of Drosophilidae, such as D. melanogaster, D. bizonata, D. immigrans and D. lutea showed 1:1 ratio in their sexes. From the results of these survey, the frequency of male flies of D. suzukii express higher than that of opposite sex at low altitude, but ratio showed the same at high in altitude. Some species of Drosophilidae (D. angularis, D. bizonata) collected at field mushroom were not recognized in their 1:1 sex ratio measured from the Chi-spuere fomular. Reason to the factors of these unbalanced ratio of sexes in the natural fields were not known.

부산광역시 지하공간의 CO 대기질 평가

이화운,박종길,장난심,이희령,김희만 한국환경과학회 2003 한국환경과학회지 Vol.12 No.1

With increasing population denities in cities, underground facilities and entertainment are proliferating at a rapid pace in efforts to maximize the use of land. The purpose of this study is to evaluate CO concentration level of subway stations having underground platforms in Busan Metropolitan City, from September to November 2000, over seven times. The places of inquiry include Yongsan-dong station. The samplings were conducted at three point of each station, i.e. gate ticket gates, and platforms. The component of CO concentration is the main elements of indoor air quality evaluation. The total concentrations and average concentration of CO were the higher at the average concentration of CO were the higher at the Somyon station. The distribution of CO concentrations at each station, generally was higher at gate than ticket gates platforms. The I?O ratios(I-platforms, O-gates) were expressed highly than 1 at the Yongsan-dong station, Busan station, Nampo-dong station and were lower 1 at others.

당뇨신발용 혁의 개발에 관한 연구

이종석,이종철,김명웅,최순복,김영길,유은일 한국공업화학회 2003 응용화학 Vol.7 No.1

The whole process of manufacturing diabatic leather for upper and lining is investigated into raw skin, pelt wet bule, crust leather and finished leather It is tried to make the more functional upper leather and lining leather in the whole leather process by the use of developed recipr. The lower chrommed wet blue for upper and lining is developed through tanning process. The air-permeability of crust leather for upper and lining is incerased through miling The hygiene of finished leather for upper and lining is increased by the of antibacterial and deodorization agents. The upper leathe and lining leather through these have the more improved physical properies of the finished leather than those through other treatments.

Halothane 마취중 Vecuronium과 Pancuronium 투여가 심혈관계 및 회복시간에 미치는 영향

길기진,김종열,이정은,김혜자,최세진 충남대학교 의과대학 지역사회의학연구소 1986 충남의대잡지 Vol.13 No.2

This study was taken to abserve the effect on cardiovascular response and recovery time with pancuronium and vecuronium. The patients was composed of 20 healthly both sex adults who belong to class I of ASA physical status. Vecuronium 0.1mg/kg(N=10) and pancuronium 0.1mg/kg(N=10) was injected independently at 20 minutes after intubation by succinylcholine 1mg/kg and thiopental sodium. The results were as follow. 1. There were not a significant difference in arterial blood pressure and pulse rate before and after vecuronium injection. 2. After pancuronium administration, arterial blood pressure was not significant change but pulse rate showed significant increasing. 3. In the recovery time when T_1 was recovered to 25% after administration of muscle relaxants respectively, there were 26±7.2 min, vecuronium and 67±11.2 min, in pancuronium. 3. EKG was not change before and after vecuronium.