구안와사 환자의 삶의 질에 대한 연구

문효,박민철,홍석훈,윤인환,이동효,이충호,김남권,Moon, Hyo,Park, Min-Cheol,Hong, Seok-Hoon,Youn, In-Hwan,Lee, Dong-Hyo,Lee, Chung-Ho,Kim, Nam-Kwon 대한한방안이비인후피부과학회 2009 한방안이비인후피부과학회지 Vol.22 No.1

Objective : The face is very important for human communication. So facial palsy patients experience not only physical disturbances but also serious emotional stress. Therefore the focus of treatment must be to not only aid the recovery of objective symptoms but also the improvement of subjective quality of life. However there has not been enough Oriental Medical study in this field until now. Thus this study was begun to suggest a useful index for the treatment of facial palsy. Methods : Grade of paralysis, sequelas, and quality of life were used for evaluation. To evaluate Grade of paralysis, House-Brackman Grade was used as the Gross scale and Kim's Grade was used as the Regional scale. Sequelas were evaluated by muscle contraction, synkinesis, NA, and grade of philtrum tilt. Quality of life was evaluated by SF-36v2, Facial Disability Index, and Vas. Results & Conclusion : 1. The change of grade of paralysis between the early and the present time reveals remarkable improvement statistically. 2. There was a remarkable improvement in all parts of quality of life except several areas of SF-36(RP, RE, MH, VT) 3. In only PF(Physical Function) of FDI, quality of life increased remarkably according to the improvement of grade of paralysis. 4. There is the positive relationship among Kim's grade, HB grade and Synkinesis 2. 5. Synkinesis among sequelas has the greatest effect on quality of life. And muscle contraction, change of NA, and grade of philtrum tilt also affect quality to some extent. 6. There was no remarkable relationship between the period of illness and change of quality of life. 7. Change of NA is shown after 3 months of illness and synkinesis becomes worse after 6 months of illness.

절수에 의한 Mongolian Gerbil 장기중량변화에 관한 분석연구

김무강,이기훈,이강이,송치원,이경열,권효정,박미선,정승혁,이행연,김명철 충남대학교 수의과대학 동물의과학연구소 2000 動物醫科學硏究誌 Vol.8 No.-

In this study, authors measured the each organ weight of the long term water deprived Mongolian gerbil, after then we calculated the mean, standard deviation, variance coefficient of the real measured organ weight and induced the organ weight change quantity, rate of quantity, deviation between measured and theological organ weight, deviation rate, sum of deviation rate, organ weight change rate, rate of organ weight by the mathematical formula. The results obtained as follow 1. The weight of the brains, lung, and testis were abruptly decreased after water deprived until the 5th day, after then slowly decreased until the 20th day. 2. The weight of the heart was decreased gradually from the first day until the 20th day. 3. The weight of the liver was abruptly decreased until the 10th day, after then the more slowly decreased until the 20th day. 4. The weight of the thymus, spleen, kidney, and pancreas were abruptly decreased until the 15th day, after then increased slowly until 20th day but the weight of the kidney was abruptly increased from the 10th day. 5. The organ weight change rate and the rate of the each day organ weight were very diversified.

8주간의 짐볼운동이 지적장애 여자청소년의 비만지수와 대사증후군 지표에 미치는 영향

김상훈,김기홍,이인경,조효구,최혜라 용인대학교 특수체육연구소 2011 특수체육연구 Vol.8 No.-

본 연구는 지적장애 여자청소년을 대상으로 8주간 짐볼운동을 실시하여 비만지수와 대사증후군 지표에 미치는 영향을 살펴보고자 실시하였다. 이를 위해 총 9명의 지적장애 여자청소년을 대상으로 준비운동과 정리운동을 포함하여 1회 50분간, 주 3회의 빈도로 총 8주간 짐볼운동을 실시하여 다음과 같은 결론을 얻었다. 비만지수의 변화를 살펴보기 위해 분석한 체지방율, 체질량지수는 감소경향이 나타났으나 통계적으로 유의하지 않았으며, 대사증후군 지표인 복부비만에서도 이와 같은 결과를 나타냈다. 대사증후군 지표의 분석에서 혈압은 수축기혈압과 이완기혈압 모두 증가경향을 나타냈으며, 중성지방과 혈당에서도 증가양상을 나타냈다. 고밀도지단백은 감소경향을 나타냈는데, 모든 변인에서 통계적 유의성은 관찰되지 않았다. 이러한 결과는 대상자들이 성장발육이 왕성한 시기이고, 연구결과에 영향을 미칠 수 있는 식이습관과 같은 다른 변인을 완벽하게 통제하지 못한 결과로 사료되며 본 연구에서 실시한 프로그램을 보완하여 8주 이상 연구를 시도했을 때 긍정적인 변화를 도출할 수 있는 가능성도 배제할 수 없을 것이다.

점포내 VMD요소가 SPA 브랜드 정체성에 미치는 영향

김소영, 손지훈, 심효진, 신동훈, 정일호, 홍동우, 김은영 충북대학교 생활과학연구소 2013 생활과학연구논총 Vol.17 No.2

This study was to examine the effect of VMD factors on brand identity for SPA brands. As brand stimulus, four SPA brands(e.g., Basic House, Codes combine, Uniqlo, Zara) were selected by pretest. For collecting data, a self-administered questionnaire was developed based on the literatures and intercept survey was conducted. A total 508 usable responses were obtained from consumers who shopped at the selected brands' stores. For data analysis, descriptive statistics, factor analysis, and regression analysis were used. As perceived by consumers, VMD consisted of seven factors: lightening, scent, color, layout, music, window display, and item presentation. The VMD factor was significantly related to brand identity for the SPA brands. Specifically, brand awareness was predicted by color, layout and item presentation; brand association strength was predicted by color, layout, and widow display; favorable brand association was predicted by item presentation; salience of brand association was predicted by color and music; and brand image association was predicted by color, layout, music, and item presentation. Thus, this study discussed a managerial implication for SPA retailers to develop a visual merchandising strategy in the competitive marketplace.

북한이탈주민의 외상 후 스트레스 장애와 자연살해세포 활성

김병창,정성훈,임효덕,최종혁,전정희,전양환 大韓神經精神醫學會 2008 신경정신의학 Vol.47 No.5

Objectives : The objective of this study was to evaluate an association between posttraumatic stress disorder (PTSD) and altered immunity m North Korean defectors who were more likely to develop medical conditions and other stress-related psychiatric disorders. Methods : Twenty-four North Korean defectors with PTSD and twenty-two controls without PTSD were recruited from the resettlement and training center for North Korean defectors in South Korea. Peripheral T lymphocyte subsets, natural killer(NK) cells, NK cell activity and plasma hormones (ACTH and cortisol) were obtained from all subjects. We also applied the Hamilton Rating Scale for Depression (HAM-D) and Hamilton Rating Scale for Anxiety (HAM-A) for all subjects. Results : We found NK cell activity was relatively lower than number of NK cells in North Korean defectors with PTSD. Subjects with PTSD had higher HAM-D and HAM-A scores than controls. However, there were no statistical differences in ACTH. cortisol, CD3, CD4, CD8, CD4/CD8 ratio, CD19 and CD56 between the two groups. Conclusion : These findings suggest North Korean defectors with PTSD show higher levels of depression, anxiety and impaired or weak immune function in NK cells.

젊은 성인에서의 하악 매복 제 3 대구치의 맹출과 위치변화에 대한 방사선학적 평가

김효섭,이재훈 大韓顎顔面成形再建外科學會 2003 Maxillofacial Plastic Reconstructive Surgery Vol.25 No.4

The third molar appears to be the most frequently impacted tooth. In most studies, the frequency of mandibular third molar impaction has been found to be 20-30%, with females showing third molar impaction significantly more often than males. During development, the position of the mandibular third molar changes countinously before reuption or impaction. Unless this movement is disturbed, the mandibular third molar will erupt normally into the functional position. Panoramic tomographs are usually taken for clincal examinaion and treatment planning. To determine the timing of surgical intervention, it would be beneficial to dertermine certain predictive signs about the future eruption from the panormic radiograph while the tooth is still developing. To estmate whether mandibular third molar are likely to erupt after the age of 20 by determining radiographic feature, we took a study on 25 patients (Average age was 20.2±0.7)with 30 impacted mandibular third molars. Panoramic radiograph was taken at age 20 and 25. The results were as follows. 76.9% of the mandibular third molars with initially complete root development fully erupted by the age of 25 years. however, teeth with incomplete root development more often remained unerupted. The mandibular third molar which impacted in only soft tissue or by the occlusal level to the mandibular second molar erupted more often than other impactions. Initially vertical angulated teeth erupted more often than other angulations. There was a statistically significant difference of angulations change between age 20 and age 25(P<0.05). In the retromolar space/MD width of mandibular third molar ratio, there was a statistically significant difference between the erupted group and the impacted group(P<0.01). It was conclued that we could find the predictive radiographic features to estimate future eruption of mandibular third molars from a panoremic tomograph taken at age 20 years.

악성 성상세포종의 수술 및 방사선의 병합 치료에 대한 임상적 고찰

김상훈,이승재,백민우,박효일 최신의학사 1982 最新醫學 Vol.25 No.2

增資所得控除制度의 財務構造改善 效果分析

洪孝錫,金東勳 진주산업대학교 1996 論文集 Vol.35 No.-

The Income Deduction Systems from Capital Increase in Korea is a tax system regulated in the Regulation Law on Tax Reduction and Exemption for the improvement of firm's financial structure. The effectiveness of this system should be tested because the system distorts the impartiality and neutrality principle of taxation. The purpose of this study is theoretically and empirically to investigate the effectiveness of the Income Deduction Systems from Capital Increase for improving the financial structure of firms in Korean tax systems. In order to bring about this purpose, this study has reviewed the related Regulation Law on Tax Reduction and Exemption and the results of previous studies on the Income Deduction Systems from Capital Increase. It was proved that the Income Deduction Systems from Capital Increase have had significant effects on the improvement of firm's financial structure. Therefore, the Income Deduction Systems from Capital Increase ought to be enforced to induce capital increase. The findings, however, should be interpreted with caution, because this study has several limitations in measurement of the Income Deduction Systems from Capital Increase and sampling. Further research studies are needed with more refined method.

李東垣의 陰火論과 朱丹溪의 相火論의 比較硏究(Ⅱ)

宋孝貞,金聖勳,金東熙,宋旭 대한동의병리학회 1998 동의생리병리학회지 Vol.12 No.2

火에 대한 槪念은 內經에서 言及한 이래 生理, 病理, 運氣的인 側面에서 여러 醫家들에 의해 多樣하게 解析되어지고 있다. 특히 古來의 理論에 얽메이지 않고 豊富한 臨床經驗을 바탕으로 李東垣은 脾胃論의 主要內容으로 '陰火論'를 主張 하였고, 朱丹溪는 歷代 醫家들의 火에 對한 槪念을 整理하여 '相火論'과 '陽常有餘 陰常不足論'을 主張하여 모두 獨特한 火의 理論을 集大成하였다. 後代에 命門學說이 나오기까지 重要한 理論·臨床的 資料를 提示하여 明代의 溫補派와 滋陰派로 集約되어 繼承되어진 東垣의 陰火와 丹溪의 相火에 대하여 歷史·環境的 背景, 槪念, 生理, 病理 및 治法 等을 諸文獻을 通하여 比較 檢討하였다. Through studing historical and environmental background, definition, physiology, pathology and therapy of Li DongWon' theory, Yin-fire, and Zhu DanXi's theory, ministerial fire, the conclusions were obtained as follows. 1. Yin-fire was a expression of debilitating heat induced by shortage of primordial Qi, even though excessive syndrome came out. 2. Ministerial fire is based on the motive power of bowel visceral activity and maintenances of life in physiology. But it is also the noxious factor that means it is the enemy of primordial Qi in pathology. 3. The etiology and pathology of Yin-fire was explained by the deficiency of spleen and stomach's vital energy caused by irregular food, overstrains and emotional stress. 4. It was thought that ministerial fire was caused by excess of emotion, fatty food and sexual intercourse and among theses factors (that gave rise to fire of bowel, visceral and Osungguelyang(五性厥陽), excessive emotion was the most important part. 5. The syndrome of yin-fire were consisted of two groups, ie. damp heat and deficiency of vital energy syndrome. And the syndrome of pathological ministerial fire is similar with the syndrome of fire among Nei-Ching's 19 pathologies, which is rapid and various. 6. Dong-Won emphasized the treating method of supplementing digestive tract and ascending yang by using sweat and warm herbs according symptom. In the other hand, DAn-Xi emphasized the treating method of nourishing yin and relieving fire by using bitter and cold herbs.

桔梗湯과 加味桔梗湯의 抗癌效果와 免疫反應에 關한 硏究

宋孝貞,金聖勳,李光浩 대한동의병리학회 1996 동의생리병리학회지 Vol.10 No.1

肺癰에 使用되고 있는 桔梗湯을, 肺癌株 및 S-180에 投與하여 抗癌 抗轉移 및 免疫效果를 實驗的으로 糾明하고, 여기에 現在 肺癌에 多用되고 있는 2가지 藥物을 加味하여 相乘效果를 觀察하고자 하였다. C57BL/6에 B16-Fo를 皮下主射하고 ICR생쥐에 S-180을 腹腔 注射한 後 桔梗湯과 加味桔梗湯을 投與하여 腫瘍重量과 體重變化, 生命延長率, 組織變化 및 血液學的變化 등을 測定하여 抗癌效果를 分析하고, 아울러 FACS에 의해 BALB/c의 脾臟免疫細胞에 대한 影響을 살펴보았다. 桔梗湯, 桔梗湯加腥草 및 桔梗湯加白花蛇舌草등은 모두 抗癌, 抗轉移 및 免疫反應에서 有意性있는 結果를 認定되었으며, 魚腥草나 白花蛇舌草를 加味하였을 경우 더욱 效果的으로 나타났다. In order to prove the antitumor effect of Kilkyungtang(KKT), Kilkyungtang with Houttuyniae Herba(KKT-I) and Kilkyungtang with Oldenlandiae diffusae Herba(KKT-Ⅱ) experimentally, the studies were done. We measured tumor mass and body weight hematological change in ICR bearing S-180 and C57BL/6 implanted with B16-Fo, also studied their effect on immune cells in BALB/c by FACS. The results were obtained as follows: 1. Body and tumor weight were significantly suppressed in all groups as compared with control group. MST(mean survival time) was 11% in KKT, 16.9% in KKT-Ⅰ, 16.1% in KKT-Ⅱ for 14 days after implantation s.c. with B16-Fo and also body weight was significantly suppressed after implantation i.p. with S-180, MST was 20.1% in KKT, 40.9% in KKT-1, 56.6% KKT-Ⅱ for 62 days. 2. WBC and platelet aggregation was significantly increased in all groups, the number of platelet was significantly increased in KKT and KKT-Ⅰ as compared with control group. 3. The infiltration of tumor cell was obvious in the white and red pulps, in the sinusoid of liver and the glomeluli of kidneys after implantation with S-180, whereas the changes of tissues were not significant in KKT-Ⅱ, KKT-Ⅰ and KKT in order. 4. T cell and T helper cell were increased in KKT-Ⅰ and KKT-Ⅱ treated groups and B cell was increased in KKT treated group as compared with control group. From above results it was concluded that Kilkyungtang(KKT), kilkyungtang with Houttuyniae Herba(KKT-Ⅰ) and Kilkyungtang with Oldenlandiae diffusae Herba(KKT- Ⅱ) had antitumor effect, and also Kilkyungtang combined with Houttuyniae Herba or Odenlandiae diffusae Herba were more effective than KKT only which suggests the necessity of continuous study on the effects of Houttuyniae Herba or Oldenlandiae diffusae Herba.