노인의 영적 간호요구

최미혜,김경희,김귀옥,김기숙,김수강,김정신,김춘숙,노흥진,박지연,성혜연,오명선,이선희,이원옥,이윤영,이현수,장명재,차혜경,채정선,홍상희 중앙대학교 의과대학 간호학과 간호과학연구소 2001 중앙간호논문집 Vol.5 No.1

This study was designed to exam the aged's needs for spiritual nursing care. The purpose was to serve as a basis for the development of spiritual nursing practice. The major findings are as follows : 1. The degree of needs for spiritual nursing care as area was that needs of love and relationship mean 22.0, needs of meaning and object mean 28.2, needs of forgiving mean 13.5. Total needs for spiritual nursing care mean 63.7, which was on the upper middle level. The needs of meaning and object was rated highest. 2. Among the general characteristics of the subjects, needs of love and relatiohship wasn't significanlty different. 3. Among the general characteristics of the subjects, needs of meaning and object was significantly different according to two factors : age(F=7.260, p=0.001), religion(F=5.275, p=0.001). Higher needs of meaning and object was possessed by the older than the younger, by the one who have religion than the other. 4. Among the general characteristics of the subjects, four factors made a significantly difference to needs of forgiving : sex(t=-2.851, p=0.006), age(F=8.201, p=0.001), religion(F=6.928, p=0.000), disease(t=2.327, p=0.024). Higher needs of forgiving was possessed by man than woman, by the older than the younger, by the one who have religion than the other, by the one who have disease than the other.

췌장 선방세포암 1예

이화정,지준호,박승찬,박정철,최은정,서혜진,이원식,이정림,배병조,손경락,이경희 영남대학교 의과대학 2008 Yeungnam University Journal of Medicine Vol.25 No.2

Acinar cell carcinoma is a rare tumor that represents 1~2% of al1 pancreatic cancers. Clinical and radiologic findings are inconclusive in this disease Acinar cell carcinoma is characterized by rapid progression and early metastasis, which lead to its poor prognosis. A 41-year-o1d man was admitted to our hospital for abdominal pain. Abdominal computed tomography (CT) and positron emission tomography-computed tomography (PET-CT) showed a splenic mass, which was being invaded by a pancreatic tail mass and which had increased ^(18)F-fluorodeoxyglucose (FDG) uptake Primary radical distal pancreatectomy and splenectomy were performed. Pathologic findings revealed an acinar cell carcinoma of the Pancreas The patient underwent a total gastrectomy three months later because of gastric recurrence Four months later, multiple hepatic metastases were discovered, and the patient underwent a left hepatectomy During treatment with capecitabine, there was no evidence of tumor progression for 14 months. We report a case of metastatic pancreatic acinar cell carcinoma, which did not progress for an extended period while the patient was being treated with capecitabme.

원발성 후복막 점액낭샘암종 1예

지준호,이화정,박승찬,박정철,최은정,서혜진,이원식,이정림,배병조,손경락,이경희 영남대학교 의과대학 2008 Yeungnam University Journal of Medicine Vol.25 No.2

Primary retroperitoneal mucinous cystadenocarcinoma is a very rare malignancy, and little is known concerning its Pathogenesis, optimal treatment, and prognosis. A 29-year-o1d pregnant woman (21 weeks) Presented with abdominal discomfort CA 19-9, CA 125, and CEA were normal Abdominal CT scanning revealed a 19x15x13 cm retropentoneal tumor Exploratory laparotomy and tumor excision were performed. Mucinous retropentoneal implants were removed as completely as possible Histologically, the tumor showed focal areas of capsular invasion, but free resection margins The uterus and both ovaries were normal in appearance No adjuvant therapy was pursued. Six months later, Peritoneal and bilateral ovarian metastases were discovered. Hence, we report the details of this case of primary retroperitoneal mucinous Cystadeno-carcinoma and present a review of the literature.

SELDI-TOF MS를 이용한 유방암 환자 진단을 위한 새로운 혈청 표지자의 개발

정용식,김호승,윤태일,전미선,윤용달,이용성,이기환,김혜진,김명욱,박희붕 한국유방암학회 2004 한국유방암학회지 Vol.7 No.1

20년전과 비교한 한국청년의 미소 변화에 관한 연구

범승균,정지혜,김태영,이경은,동진근 大韓齒科補綴學會 2012 대한치과보철학회지 Vol.50 No.3

Purpose: Teeth are generally exposed when people smiling. Moreover, the exposed teeth and soft tissue when smiling becomes an important guideline for esthetically prosthetic restoration. This research is to compare and find out differences of Korean young men's smile living in presence and twenty years ago. Materials and methods: Subjects, 100 young men (50 male and 50 female), were required about several aspects; normally developed physical condition, no psychological or genetic disorders, a fine face with no loss of teeth, no experience in orthodontic or prosthetic treatment, relatively normal occlusion, aged between 20 - 29. The photos of the subject at rest position and front face when fully smiled were taken three times. 100 photos (50 male and 50 female) were chosen at random from the 240 university students' smile photos taken by Yoon and his colleagues in 1991. By Hulsey's method of measuring smile, several factors; the change of upper lip curvature, the change of the relation between the upper lip and teeth, parallelism between Mx. incisor and lower lip, contact relation between Mx. incisor and lower lip and teeth displayed in a smile, were measured and analyzed. Meanwhile, ten dentists assessed aesthetic evaluation about men and women's smile for twice and recorded and compared smile score. The -test (P<.05) was used to compare the measured value. The difference of smile score was analyzed by t-test (P<.05). Results: The smile score calculated in 2011 (60.22) was higher than that of 1991 (52.80). Among five measurement categories, the noticeable difference was distinguished from two factors; the change of upper lip curvature and contact relation between Mx. incisor and lower lip. Conclusion: The Korean young men's smile has been considerably improved for twenty years. And it is found that the change of upper lip curvature plays an important role, that is, the smile formed with an ascended labial commissure has been increased significantly. 연구 목적: 일반적으로 치아는 미소 지을 때 가장 많이 노출되며, 미소 시에 나타나는 치아와 연조직과의 관계 등은 심미적인 보철 수복에 있어서 중요한 지침이 된다. 본 연구는 20년 전 한국 청년들의 미소와 현재 한국 청년들의 미소를 비교하여 그 차이를 알아보고자 하였다. 연구 재료 및 방법: 신체적인 발육 상태가 정상적이고 전신적 또는 유전적 질환이 없으며, 안모가 양호하고 치아의 결손이 없으며 교정 및 보철치료를 받은 경험이 없고, 교합상태가 비교적 정상적인 20 - 29세 사이의 청년 100명(남자 50명, 여자 50명)을 대상으로, Cephalometer에 사용되는 두부 고정 장치를 사용하여 피검자의 F-H plane이 지면에 평행하도록 한 후, 35 mm 카메라(400D. Cannon, Japan), 120 mm 렌즈 그리고 삼각대를 사용하여 피검자의 midsagittal plane에 카메라 렌즈의 중심을 맞추고 상악 중절치 절단과 렌즈와의 거리를 930 mm로 하여 안정위 및 full smile 시의 안모 정면 사진을 3회씩 촬영하였다. 1991년 윤 등이 촬영한 대학생 240명 중 무작위로 선택한 100명(남자 50명, 여 자 50명)의 미소사진과 함께 개인용 컴퓨터 및 V-ceph 6.0 프로그램을 이용하고 Hulsey의 미소 계측 방법을 참고로 하여, 상순의 형태, 상순과 치아와의 관계, 하순과 상악 전치 절단연과의 평행 관계, 하순과 상악 전치 절단연과의 접촉 관계, 미소시 나타나는 치아 등을 계측하고 분석하였다. 한편 치과의사 10인이 남,녀 각 2회씩 미소에 대한 미적 평가를 시행하여 미소평점을 기록하고 비교하였다. 결과: 지난 20년간 한국 청년의 미소가 크게 향상되었으며 이러한 변화는 주로 상순의 형태가 영향을 준 것을 알 수 있었다. 즉 입꼬리가 위로 올라가는 형태의 미소가 괄목할 만한 증가를 보인 반면 입 꼬리가 아래로 처지는 형태의 미소는 현저한 감소를 보였다. 결론: 지난 20년간 한국 청년의 미소가 크게 향상되었는데 이러한 변화는 주로 상순의 형태가 영향을 준 것으로 나타났다.

디지털 기술의 건강보험 보장방법에 대한 고찰: 5개 국가 중심

엄혜은,김지혜,한승진,최연미,최윤정 건강보험심사평가원 2022 HIRA RESEARCH Vol.2 No.1

Whole-genome resequencing analysis of 20 Micro-pigs

Da‑Hye Son,Nam‑Hyun Hwang,Won‑Hyong Chung,Ha‑Seung Seong,Hyungbum Lim,Eun‑Seok Cho,Jung‑Woo Choi,Kyung‑Soo Kang,Yong‑Min Kim 한국유전학회 2020 Genes & Genomics Vol.42 No.3

Background Miniature pigs have been increasingly used as mammalian model animals for biomedical research because of their similarity to human beings in terms of their metabolic features and proportional organ sizes. However, despite their importance, there is a severe lack of genome-wide studies on miniature pigs. Objective In this study, we performed whole-genome sequencing analysis of 20 Micro-pigs obtained from Medi Kinetics to elucidate their genomic characteristics. Results Approximately 595 gigabase pairs (Gb) of sequence reads were generated to be mapped to the swine reference genome assembly (Sus scrofa 10.2); on average, the sequence reads covered 99.15% of the reference genome at an average of 9.6-fold coverage. We detected a total of 19,518,548 SNPs, of which 8.7% were found to be novel. With further annotation of all of the SNPs, we retrieved 144,507 nonsynonymous SNPs (nsSNPs); of these, 5968 were found in all 20 individuals used in this study. SIFT prediction for these SNPs identified that 812 nsSNPs in 402 genes were deleterious. Among these 402 genes, we identified some genes that could potentially affect traits of interest in Micro-pigs, such as RHEB and FRAS1. Furthermore, we performed runs of homozygosity analysis to locate potential selection signatures in the genome, detecting several loci that might be involved in phenotypic characteristics in Micro-pigs, such as MSTN, GDF5, and GDF11. Conclusion In this study, we identified numerous nsSNPs that could be used as candidate genetic markers with involvement in traits of interest. Furthermore, we detected putative selection footprints that might be associated with recent selection applied to miniature pigs.

DNA 증거의 집단유전학적 분석을 위한 SAS시스템

이효정,이혜승,한길로,이재원,황적준 大韓法醫學會 2000 대한법의학회지 Vol.24 No.1

DNA analysis has become one of the most powerful tools in forensic inference for human identification and is now used worldwide. It is used to be statistical technique for the individual identification of a civil and criminal action. The purpose of this article is computerization of the statistical technique for the population study and DNA evidence analysis. The system using SAS/AF and SAS/SCL is the graphic user interface and the correspondence of the changed experimental circumstances

자궁경부 상피내종양의 진단 및 치료에서 환상 투열요법(LLETZ)의 임상적 의의

김승철,이경순,김영주,정혜원,안정자 梨花女子大學校 醫科大學 醫科學硏究所 1994 EMJ (Ewha medical journal) Vol.17 No.4

The technique of large loop excision of the transformation zone(LLETZ) as an alternative to destructive/ablative methods of treatment of CIN(cervical intraepihelial neoplasia) such as cryotherapy, laser vaporization and cone biopsy was assessed. In 63 women with suspected CIN attending the colposcopy clinic, the histologic diagnoses made from excision biopsies taken by LLETZ were compaired with those from colposcopically directed punch biopsies. This microinvasive tumors were found by LLETZ and the diagnosis made by LLETZ was worse than that made by punch biopsy in 17 cases(26.9%). That is to say, LLETZ improves the accuracy of diagnosis of CIN. And in offers a cheap and accurate alternative to laser vaporization or cone biopsy, and also combines the benifits of the gold standard cone biopsy with that of local ablative metholds. LLETZ is considered as a fairly new and good method of treatment of CIN, and the olng-term complications or effects should by yet fully evaluated in future.

상악 중절치부위의 과잉치에 대한 증례보고

박희승,정향숙,김용기,정희민 大韓小兒齒科學會 1990 大韓小兒齒科學會誌 Vol.17 No.2

The term “Mesiodens” refers to a supernumerary tooth that is present in the midline of the anterior maxilla. Supernumerary tooth results from aberrations in the initiation or proliferation period of dental developmental stage. The crown often has a conical shape, and its familial incidence has been reported in several instances. The author has observed 71 cases of supernumerary tooth occured at premaxilla between central incisors. Among the total tooth number of 86,70 were impacted, and 16 were erupted. In most cases(96.5%), supernumerary tooth located on the palatal side of adjacent teeth. Surgical and/or orthodontic treatment were performed in 53 cases, 21 cases, were left untreated for delayed surgical intervention.