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      • KCI등재

        저용량 브로모크립틴 치료로 반복적인 정상 임신과 종양 감퇴를 보인 거대프로락틴선종 1예

        최혜정,박진용,김희영,서지아,김신곤,김난희,최경묵,백세현,최동섭,최우석,송종규 대한내분비학회 2009 Endocrinology and metabolism Vol.24 No.1

        Prolactin-secreting adenomas are the most common pituitary tumors. Menstrual disturbances and infertility are the main complaints in women with prolactinoma. Dopaminergic agonists such as bromocriptine are well-established treatments for prolactinoma when pregnancy is desired. Pregnancy-related outcomes in macroprolactinoma are worse than those in microprolactinoma. In addition, symptomatic tumor expansion during pregnancy occurs in 30% of women with macroprolactinoma. Therefore, when women with macroprolactinoma are planning a pregnancy, serum prolactin level should be normalized and the tumor volume significantly reduced. On the other hand, a spontaneous regression of macroprolactinoma can occur after pregnancy. We report a case of macroprolactinoma showing significant tumor regression during repeated pregnancies and low dose bromocriptine treatment, with a literature review.

      • KCI등재후보

        교육복지우선지원사업에서의 주기주도성 프로그램의 질적 연구: 지역사회교육전문가 포커스 그룹 인터뷰를 중심으로

        최혜정 한국복지상담교육학회 2016 복지상담교육연구 Vol.5 No.1

        The purpose of this study is to recognize the importance of the self-directed program in the education welfare priority support project, explore practical experience of the community education specialists, and to find an applicable alternative. For this, using the intentional sampling method, this study carried out a focus group interview, by organizing two groups with 15 community education specialists, who had an experience of practicing the self-directed program. As a result of the study, the concept of the self-directed program in children who participated in the education welfare priority support project was the process of learning how to cope with life in success and failure. Besides, as the program provided an opportunity to explore ‘the self’ for the education welfare target children, it was analyzed to have an advantage of effectiveness of killing two birds with one stone, that both students and community education specialists grew together. On the other hand, a difficulty in the self-directed program expanded in school is that poor working conditions led to distrust in clients. It was also found the self-examination and self-reflection of doers had to be prepared to implement the self-directed program. Therefore, in stabilizing the education welfare priority support project, this study has significance that it became the basic data for suggesting necessity and practical possibility of the self-directed program. 본 연구의 목적은 교육복지우선지원사업에서 자기주도성 프로그램의 중요성을 인식하고 지역사회교육전문가들의 실천 경험을 탐색함으로서 활용 가능한 대안을 모색하는 데에 있다. 이를 위해 의도적 표집방법을 활용하여 학교 현장에서 자기주도성 프로그램을 실천해 본 경험을 가지고 있는 지역사회교육전문가 15명을 2집단으로 구성하여 포커스그룹 인터뷰를 실시하였다. 연구결과, 교육복지우선지원사업에 참여하는 아동에게 자기주도성 프로그램의 개념은 성공과 실패 속에서 삶의 대처경험을 터득하는 과정이었다. 더불어 교육복지 대상 아동에게 ‘자기’를 탐색할 기회를 제공하는 것으로 프로그램의 강점은 학생과 지역사회교육전문가가 같이 성장하는 일거양득의 효과성이 나타나는 것으로 분석되었다. 반면, 자기주도성프로그램이 학교 현장에 확산되기 어려운 이유로는 열악한 근무환경이 클라이언트에 대한 불신으로 이어지는 것으로 드러났으며, 실천가들의 자기 성찰과 반성이 필요함을 알 수 있었다. 이에 본 연구의 의의는 교육복지우선지원사업의 안정화를 위해 자기주도성 프로그램의 필요성 및 실천 가능성을 제시하는 기초자료가 되었다는 데에 있다. 이를 기반으로 교육복지우선지원사업에 참여하고 있는 아동 청소년의 건강한 성장발달을 도모하는 전문적 프로그램의 발전을 위한 방안을 모색할 필요가 있음을 시사한다.

      • KCI등재

        식은 땀을 호소하는 진행성 암 환자에서 비스테로이드성 항염증 제제를 이용한 치료

        최혜정,송하나,강정훈,Choi, Hye Jung,Song, Haa-Na,Kang, Jung Hun 한국호스피스완화의료학회 2016 한국호스피스.완화의료학회지 Vol.19 No.4

        목적: 진행성 암 환자에서 발열이 동반되지 않은, 암성 발한에서 NSAID (non-steroid anti-inflammatory drug) 치료 효과를 알아보고자 함이 목적이다. 방법: 다음과 같은 조건을 만족하는 환자를 대상으로 후향적으로 의무 기록을 조사하였다. 1) 수술적 절제나 항암방사선 치료로 완치가 불가능한 진행성 암 환자 2) 숫자평가등급 4점 이상의 식은 땀을 호소하며 발열이 동반되지 않은 환자 3) 식은 땀의 원인이 될 만한 감염이 없고, 마약성 진통 및 호르몬 차단제를 현재 최근 1개월 이내 새롭게 사용하지 않는 환자 4) 식은 땀 치료를 위해 NSAID를 사용하고, NRS 평가가 치료 전 후 시행한 환자. 결과: 총 13명의 환자가 등록되었다. 남자가 9명(69%)이었고, 평균 59세(범위: 50~71)였다. 암종별 빈도는 담도암, 췌장암, 위암, 전립선암 순이었다. 치료 전 환자들의 식은 땀은 평균 NRS 6.5 (최소값: 4, 최대값: 10) 이었고, 치료 후에는 NRS 1.9 (최소값: 0, 최대값: 5)이었다. 평균 추적 관찰 기간은 9.1일이었다. 결론: 진행성 암 환자에서 열이 동반되지 않은 중등도 이상의 식은 땀 환자에서 NSAID는 효과적인 치료방법이다. Purpose: Advanced cancer may accompany cold sweat as paraneoplastic symptom. Few studies have been performed on the efficacy of non-steroid anti-inflammatory drug (NSAID) in advanced cancer patients who sweated without fever. Methods: To select study participants, medical records were retrospectively reviewed for patients who satisfied the following criteria: 1) incurable, advanced solid cancer; 2) Cold sweating of 4 or higher on the numeric rating scale (NRS) 4; 3) No evidence of infection or hypoglycemia; 4) No newly started opioid or anti-hormonal agents within one month; 5) NSAID prescription for the management of cold sweating and 6) Documented NRS information before and after NSAID administration. Results: A total of 13 patients were selected after excluding four patients due to lack of NRS information or fever. The mean age was 59 years old (range: 50~71), and nine patients (69%) were male. Bile duct cancer was the most common primary tumor followed by pancreatic cancer, gastric cancer and prostate cancer. The mean NRS of cold sweating dropped from baseline 6.5 (min-max: 4~10) to 1.9 at the follow-up assessment (min-max: 0~5). The mean follow-up period was 9.1 days (range: 2~30 days) from NSAID treatment to assessment. Conclusion: NSAID was effective medication for management of sweating without fever in patients with advanced cancer.

      • KCI등재

        Effects of Planting on the Prefrontal Electroencephalogram Activity of University Students

        최혜정,김미진,신호식,윤숙영 인간식물환경학회 2023 인간식물환경학회지 Vol.26 No.4

        Background and objective: This study was conducted from June 1 to August 30, 2021 with 33 students at Daegu CatholicUniversity to investigate the effect of planting on the theta, alpha, beta, and gamma waves of the prefrontal cortex. Methods: For the experiment, the subjects wore electroencephalogram (EEG) sensors and proceeded through thefollowing three steps: 1) preparation stage: looking at the wall (2 min), 2) work stage: planting plants (5 min), and 3)appreciation stage: looking at and appreciating the plants they planted (3 min). Results: As a result of analyzing the total relative values of the preparation, work, and appreciation stages in the raw data(excluding the delta wave, which increases during sleep), the alpha wave increased in the work stage of planting activity(Left: p = .000, Right: p = .000). Alpha waves are brain waves that are activated in states of relaxation, rest, and euphoria. In male students, alpha waves (Left: p = .001, Right: p = .001) were activated in the work stage. In female students, therewas a significant difference in all EEG activity between the stages. Theta wave (Left: p = .046, Right: p = .029) was mostactivated in the appreciation stage, and the alpha wave (Left: p = .000, Right: p = .000) was most activated in the workstage. Beta waves (Left: p = .016, Right: p = .013) and gamma waves (Left: p = .015, Right: p = .011) were found to beinactivated in the work stage. Conclusion: The study results facilitated the investigation of planting effectiveness according to the type of activity bymeasuring the EEG for each activity stage.

      • KCI등재

        손자녀 양육을 지원하는 조모가 성인자녀에 대해 갖는 양가감정에 영향을 미치는 변인 : 고부관계와 모녀관계를 중심으로

        최혜정,정미라 한국아동가족복지학회 2019 한국가족복지학 Vol.24 No.2

        The purpose of this study was to examine the personal and relational variables affecting on the ambivalent feelings that grandmother has about their adult children. The participants were 355 grandmothers rearing their grandchildren in Seoul and Gyeonggi-do. The Data were analyzed by descriptive statistics, correlation analysis, and hierarchical regression analysis using statistical program SPSS 23.0. The results of the study are as follows. First, the neuroticism in grandmother was associated with greater ambivalence. The conscientiousness was associated with less ambivalence toward the daughter, and with greater ambivalence toward the daughter-in–law. Second, the consensual solidarity was associated with less ambivalence. The normative solidarity was associated with greater ambivalence, and this was significant only for the daughter-in-law relationship. Third, the negative social exchanges was associated with greater ambivalence. Fourth, sociodemographic characteristics such as caring time and education level of grandmother were related only to ambivalence toward the daughter-in-law. Based on the results of this study, we discussed how to reduce the ambivalent feelings of grandmother.

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