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이지혜,박철한,최은정 한국건설산업연구원 2023 한국건설산업연구원 건설동향브리핑 Vol.2023 No.-
건설업 사망사고, 사고유형별 맞춤 대책 필요 (이지혜) - 가장 많은 사고유형은 ‘떨어짐’, 주요 원인은 ‘작업자’의 ‘단순과실’ - 건설경기, 내년 2/4분기 전후 침체기 진입 전망 (박철한) - 2024년 건축공사 위주로 감소 예상, 공공·민간 침체기 대비한 선제적 대응 필요 - 미국과 호주의 건설기술인 교육기관 평가와 시사점 (최은정) - 교육 커리큘럼의 질적 평가 최우선, 수요자 니즈 반영에 노력 기울여 -
The Effect of Troglitazone on Thermal Sensitivity in Uterine Cervix Cancer Cells
이지혜,김원동,유재란,박우윤 대한방사선종양학회 2010 Radiation Oncology Journal Vol.28 No.2
Purpose: Troglitazone (TRO), a PPAR-γ agonist, can reduce heat shock protein (HSP) 70 and increase the antioxidant enzymes, such as superoxide dismutase (SOD) and catalase, which might affect thermal sensitivity. Here, we investigated whether TRO modifies thermal sensitivity in uterine cervical cancer cells, which is most commonly treated by hyperthermia (HT). Materials and Methods: HeLa cells were treated with 5μM TRO for 24 hours before HT at 42oC for 1 hour. Cell survival was analyzed by clonogenic assay. The expression of HSPs was analyzed by Western blot. SOD and catalase activity was measured and reactive oxygen species (ROS) was measured using 2',7'-dichlorofluorescin diacetate and dihydroethidium. Results: The decreased cell survival by HT was increased by preincubation with TRO before HT. Expression of HSP 70 was increased by HT however, it was not decreased by preincubation with TRO before HT. The decreased Bcl-2 expression by HT was increased by preincubation with TRO. SOD and catalase activity was increased by 1.2 and 1.3 times,respectively with TRO. Increased ROS by HT was decreased by preincubation with TRO. Conclusion: TRO decreases thermal sensitivity through increased SOD and catalase activity, as well as scavenging ROS in HeLa cells.
이지혜,허난 한국수학교육학회 2018 수학교육논문집 Vol.32 No.1
Recently, we are working to utilize it in various fields with the expectation of the potential of artificial intelligence. There is also interest in applying to the field of education. In the field of education, machine learning and deep learning, which are used in artificial intelligence technology, are deeply interested in how to learn on their own. We are interested in how artificial intelligence and artificial intelligence technologies can be used in education and we have an interest in how artificial intelligence can be applied to mathematics education. The purpose of this study is to investigate the direction of mathematics education as the change of education paradigm and the development of artificial intelligence according to the development of information and communication technology. Furthermore, we examined how artificial intelligence can be applied to mathematics education. 인공지능(Artificial Intelligence)의 잠재력에 대한 기대로 여러 분야에서 이를 활용하고자 노력하고 있으며 교육 분야에서의 적용에 대한 관심 역시 높다. 교육에 있어서 인공지능 기술에 활용되는 기계학습(machine learning)과 딥러닝(deep learning)으로 스스로 학습하는 방법에 대한 관심을 가지게 되었으며 이러한 방식이 교육에 어떻게 활용될 수 있을 지와 인공지능을 어떻게 수학교육에 적용할 수 있을지에 대한 관심이 대두되고 있다. 이에 정보통신기술의 발달에 따른 수학교육의 변화를 고찰해 봄으로써 수학교육의 변화가 인공지능과 어떠한 연과성이 있는지를 살펴보는데 의의가 있다고 할 수 있다.
베트남인 한국어 학습자의 읽기 능력과 쓰기 능력의 상관관계 연구 -학술적 텍스트를 중심으로-
이지혜,김수미 한국언어문화교육학회 2018 언어와 문화 Vol.14 No.3
This study was aimed at measuring the correlation between the academic text reading ability and the writing ability of Vietnamese KSL students, to investigate the correlation of both abilities, and to draw out the educational implications through such a research. For this purpose, a total of 32 Vietnamese KSL students participated in this experiment. In order to measure their reading abilities, this study used a total of 20 questions consisting of sentence arrangement, theme identification, detail content identification, and inference type questions. Furthermore this study also investigated the learners’ writing abilities by using writing type questions that are typically used during a TOPIK exam. The results from analyzing their data were as follows. First, similar to findings of previous researches, it was found that the Vietnamese participants‘ reading ability of Korean was positively correlated with their writing ability. Second, the Vietnamese learners various use of vocabulary, grammar and expressions among the Korean writing ability showed a much better reading ability in Korean. Third, it also identified that the learners showed more ability to arrange necessary sentences that produced more logical and persuasive writing. Fourth, participants were more easily able to understand the reading and/or writing text if they already had some knowledge of the subject. Fifth, it showed that only writing experience in Korean had a positive influence on their overall writing ability. Based on these results, it is suggested that the education of the Korean language can be further developed by linking reading and writing instructions. In particular, education of the Korean language needs to practically demonstrate the characteristics of Korean written text and help learners to utilize them.
Clinical Predictors of the Region of First Structural Progression in Early Normal-tension Glaucoma
이지혜,이광현,성공제,김찬윤,Sang Yeop Lee,배형원 대한안과학회 2020 Korean Journal of Ophthalmology Vol.34 No.4
Purpose: This study aimed to compare the clinical characteristics of patients who showed structural progression in the peripapillaryretinal nerve fiber layer (RNFL) first against those who showed progression in the macular ganglion cell-inner plexiformlayer (GCIPL) first and to investigate clinical parameters that help determine whether a patient exhibits RNFL or GCIPLdamage first. Methods: A retrospective review of medical records of patients diagnosed with early-stage normal-tension glaucoma wasperformed. All eyes underwent intraocular pressure measurement with Goldmann applanation tonometer, standard automatedperimetry, and Cirrus optical coherence tomography at 6-month intervals. Structural progression was determinedusing the Guided Progression Analysis software. Blood pressure was measured at each visit. Results: Forty-one eyes of 41 patients (mean age, 52.6 ± 16.7 years) were included in the study. In 21 eyes, structural progressionwas first detected in the RNFL at 54.2 ± 14.8 months, while structural progression was first observed at the macularGCIPL at 40.5 ± 11.0 months in 20 eyes. The mean intraocular pressure following treatment was 13.1 ± 1.8 mmHg for theRNFL progression first group and 13.4 ± 1.8 mmHg for the GCIPL progression first group (p = 0.514). The GCIPL progressionfirst group was older (p = 0.008) and had thinner RNFL at baseline (p = 0.001). The logistic regression analyses indicated thatboth age and follow-up duration until first progression predicted the region of structural progression (odds ratio, 1.051; 95%confidence interval, 1.001–1.105; p = 0.046 for age; odds ratio, 0.912; 95% confidence interval, 0.840–0.991; p = 0.029 fortime until progression). Conclusions: Age of glaucoma patients and time until progression are associated with the region of the first structural progressionin normal-tension glaucoma. Further studies exploring the association between glaucomatous progression and thelocation of damage are needed.