과루인약침(瓜蔞仁藥鍼)이 Ovalbumin-induced Asthma Mouse Model에 미치는 영향(影響)

김정현,백경민,이현의,김종원,오병열,조현경,유호룡,김윤식,설인찬,심재철,Kim, Jung-Hyun,Baek, Kyung-Min,Lee, Hyun-Eui,Kim, Jong-Won,Oh, Byeong-Yeol,Jo, Hyun-Kyung,Yoo, Ho-Rhyong,Kim, Yoon-Sik,Seol, In-Chan,Shim, Jae-Chul 대한한방내과학회 2005 大韓韓方內科學會誌 Vol.26 No.3

Objectives : The aim of this study was to investigate the effect of Trichosanthis Semen Herbal-acupuncture(TS-HA) at Joksamni(ST36) on ovalbumin-induced asthma in mice. Methods : C57BL/6 mice were sensitized and challenged with ovalbumin(OVA) once a week for twelve weeks. The experimental group was treated with 1% concentrations of TS-HA at Joksamni(ST36) three times a week for the last eight weeks. Results : 1. The weight and total lung cells of the mice in the group treated with TS-HA decreased significantly compared with those of control group. 2. Total leukocytes and eosinophils in Bronchoalveoler-lavage fluid(BALF) of the mice in the group treated with TS-HA decreased significantly compared with those of control group. 3. Eosinophils in BALF of the mice in the group treated with TS-HA in photomicrographs decreased significantly compared with those of control group. 4. According to histological analysis of lung sections, adhension of collagen in TS-HA decreased significantly compared with that of control group. 5. The concentration of IgE, IL-4, IL-5 in BALF and IL-4, IL-5, IL-13 in serum of the mice in the group treated with TS-HA decreased significantly compared with that of control group. 6. The number of $Gr-^+/CD11b^+,\;CD11b^+,\;CD3e^-/CCR3^+,\;CD4^+,\;CD8^+\;CD3e^+/CD69^+,\;CD23^+/B220^+\;cells$ in the lungs of the mice in the group treated with TS-HA decreased significantly compared with those of control group. Conclusion : These results suggest that Trichosanthis Semen-herbal acupuncture at Joksamni(ST36) done on C57BL/6 mice is effective in part in relieving OVA-induced asthma in C57BL/6 mice.

랜덤화 블록 계획법에서 우산형 대립가설에 대한 정렬방법과 위치를 이용한 비모수 검정법

김정현,김동재,Kim, Jeonghyun,Kim, Dongjae 한국통계학회 2016 응용통계연구 Vol.29 No.7

랜덤화 블록 계획법(randomized block design)에서 대립가설형태에 따라 많은 비모수적인 방법들이 제안되었다. 일반대립가설에서 대표적으로 Fridman (1937)의 검정법이 있고, 순서형 대립가설에서는 Page (1963)의 검정법이 있다. 우산형 대립가설에 대한 비모수적 방법으로는 일원 배치 모형에서 k개의 표본 문제에 대하여 Mack과 Wolfe (1981)의 검정법이 있다. 본 논문에서는 랜덤화 블록 계획법(randomized block design)에서 우산형대립가설에 대하여 블록 간의 정보를 이용한 Hodges와 Lehmann (1962)의 정렬방법과 위치를 이용한 Kim (1999)의 검정법을 이용하여 검정법을 제안하였다. 또한, Monte carlo 모의실험을 통하여 제안된 검정법과 기존의 검정법을 비교하였다. Nonparametric methods in randomized block design were suggested by Friedman (1937) for general alternatives and were also proposed by Page (1963) for ordered alternatives in one-way layout; in addition, K-sample rank tests for umbrella alternatives were suggested by Mack and Wolfe (1981). In this paper, we proposed a nonparametric method of umbrella alternatives for randomized block design using the aligned method proposed by Hodges and Lehmann (1962) to use block information and using placement suggested by Kim (1999). Monte Carlo simulation was also adapted to compare the power of the proposed procedure with previous methods.

벌독으로 인한 혈청병 양상의 두드러기 및 맥관부종 치험 1례

김정현,강다혜,김지영,임해원,김자헌,권강,Kim, Jung-Hyun,Kang, Da-Hae,Kim, Jee-Young,Lim, Hae-Won,Kim, Ja-Heon,Kwon, Kang 대한한방안이비인후피부과학회 2011 한방안이비인후피부과학회지 Vol.24 No.3

Objective : This study was performed to prove the effect of the oriental medical treatments on urticaria and angioedema caused from serum sickness reaction by bee venom. Method : We treated one case of urticaria and angioedema with oriental medical treatments such as 8 constitution acupuncture, herbal medicine, venesection therapy and facial pack therapy. We took pictures through the treatment to evaluate the improvement. Six items, itching, burning sensation, pain, wheal, redness, edema were used to diagnose urticaria and angioedema. Result & Conclusion : After treatments the urticaria and angioedema were improved. The symptom of itching, heating, pain, wheal, redness of whole body and facial edema disappeared.

사용자지정 재료 서브루틴을 활용한 LNG선박 단열시스템 멤브레인의 수치해석

김정현,김슬기,김명수,이제명,Kim, Jeong-Hyeon,Kim, Seul-Kee,Kim, Myung-Soo,Lee, Jae-Myung 한국전산구조공학회 2014 한국전산구조공학회논문집 Vol.27 No.4

304L 스테인리스강판은 멤브레인타입 LNG선 단열시스템의 1차 방벽으로 이용된다. 304L 스테인리스강은 변태유기소성(TRIP)강으로 복잡한 재료거동을 보이는데, 이는 소성변형이 발생하는 동안 상변태를 경험하기 때문이다. 본 연구에서는 304L 스테인리스 강의 비선형 기계적 거동분석을 위한 온도의존 일축인장시험을 수행하였으며 재료의 파단이나 비선형 거동을 예측하기 위한 점소성모델을 제안하였다. 수치해석의 결과와 시험 결과를 비교 분석하여 유효성을 검증하였으며 LNG 멤브레인에 대한 적용성을 검토하기 멤브레인 구조시편을 제작하여 구조해석 및 유한요소해석을 수행하였다. 재료모델은 개발 서브루틴을 이용하였으며 ABAQUS 사용자지정 재료 서브루틴을 탑재한 유한요소해석 결과와 극저온 구조인장시험을 수행한 결과를 비교하여 구조적용성을 검증하였다. 304L stainless steel sheets are used as a primary barrier for the insulation of membrane-type liquefied natural gas(LNG) carrier cargo containment system. 304L stainless steel is a transformation-induced-plasticity(TRIP) steel that exhibits complex material behavior, because it undergoes phase transformation during plastic deformation. Since the TRIP behavior is very important mechanical characteristics in a low-temperature environment, significant amounts of data are available in the literature. In the present study, a uniaxial tensile test for 304L stainless steel was performed to investigate nonlinear mechanical characteristics. In addition, a viscoplastic model and damage model is proposed to predict material fractures under arbitrary loads. The verification was conducted not only by a material-based comparative study involving experimental investigations, but also by a structural application to the LNG membrane of a Mark-III-type cargo containment system.

식물학의 학문분류와 문헌분류 체계에 관한 비교 연구

김정현,Kim, Jeong-Hyen 한국도서관정보학회 2008 한국도서관정보학회지 Vol.39 No.3

이 연구는 식물학의 학문분류 체계와 문헌분류 체계를 비교 분석함으로써 식물학의 분류특성과 문제점을 분석하고, 이를 토대로 KDC 식물학의 분류체계를 개선할 수 있는 방안을 제시하고자 시도되었다. 이 연구결과를 요약하면 아래와 같다. 첫째, 식물학의 학문분류는 주로 식물의 연구대상에 따라 식물 형태학, 식물 생리학, 식물 생태학, 식물 계통학, 식물 유전학, 식물 진화학 등으로 구분하고 있다. 둘째, 식물의 분류는 식물 계통학이라는 하위 분과학문에서 다루고 있으며, Engler 체계 등이 일반화되어 있다. 셋째, 식물학의 문헌분류 체계는 대부분 식물학의 분과학문 위주가 아니라 식물의 분류 위주로 구성되어 있다. 이때 KDC, NDC, UDC, CC에서는 식물분류를 식물의 발달과정 즉, 진화순서에 의해 하등식물에서 고등식물로 배열되어 있는 Engler 체계를 적용하고 있으며, DDC와 LCC는 현존하는 식물에 더 중점을 두고, 고등식물에서 하등식물로 배열되어 있는 Bentham & Hooker 체계와 유사성이 있다. 넷째, KDC 식물학에서 있어서는 DDC나 CC와 같이 일반 식물학에서 다루고 있는 식물의 구조나 속성 등을 482-489에 나열되어 있는 모든 식물에 공통적으로 적용하여 세분할 수 있도록 구조화 하는 것이 바람직할 것이다. The purpose of this study is investigate to compare with knowledge classification and library classification system of botany. First, the knowledge field of botany is mainly classified in morphology, physiology, ecology, taxonomy, genetics, evolution and others by the study object of plants. Second, the division of plants is treated in the field of taxonomy, that is, a lower subdivision study of botany, and Engler's classification is still prevalent in the taxonomy. Third, in library classification, KDC, NDC, UDC and CC adopted the Engler's classification, but DDC and LCC was taken of the Bentham & Hooker's classification. In the Engler's classification, plants are arranged by evolution's order, from lower vegetation to higher vegetation, but Bentham & Hooker's classification is arranged in the reverse order. Forth, it is desirable that every plants(482-489) of KDC' botany are subdivided by the attribute or structure of plants being treated in the general botany as if they are subdivided in the DDC or CC.

순환/재생골재의 잔류 모르타르 성분이 알칼리 실리카 반응성에 미치는 영향 평가

김정현,김남호,양성철,Kim, Jeonghyun,Kim, Namho,Yang, Sungchul 한국도로학회 2015 한국도로학회논문집 Vol.17 No.4

PURPOSES : The objective of this study is to evaluate the effect of the residual mortar of recycled concrete aggregate on the expansion behavior during alkali silica reaction (ASR). METHODS: In order to evaluate the net effect of residual mortar on ASR expansion behavior, two aggregate samples with the same original virgin aggregate source but different residual mortar volumes were used. ASTM C1260 test was used to evaluate the ASR expansion behavior of these two aggregates and the original virgin aggregate. RESULTS: The greater the amount of residual mortar in recycled concrete aggregates, the less is the induced ASR expansion. Depending on the amount of residual mortar in recycled concrete aggregate, the ASR expansion of recycled concrete aggregate may be less than half of that of the original virgin aggregate. CONCLUSIONS: The residual mortar of recycled concrete aggregate may lead to the under estimation of the ASR expansion behavior of the original virgin aggregate.

승마기구에서 골반자세와 속도가 몸통 및 다리 근 활성에 미치는 영향

김정현,장수경,Kim, Jung-Hyun,Chang, Soo-Kyung 대한물리치료학회 2014 대한물리치료학회지 Vol.26 No.5

Purpose: The purpose of this study was to assess the effects of robo-horseback riding with changes of pelvic tilting and speeds on muscle activities of trunk and lower limb in healthy adults. Methods: Thirty healthy adults were recruited for this study. Subjects performed robo-horseback riding at three pelvic postures (anterior tilting pelvic posture: AP, neutral pelvic posture: NP, posterior pelvic posture: PP) and different speeds (moderate and fast speed). Muscle activities were recorded from the trunk muscles (rectus abdominis [RA], T2 paraspinalis [T2 PS], L2 paraspinalis [L2 PS]) and lower limb muscles (rectus femoris [RF], vastus medialis [VM], vastus lateralis [VL], biceps femoris [BF], gastrucnemius [GCM]). Results: Significantly higher RA activities were observed under the PP condition than under the AP and NP conditions at both speeds. Significantly higher L2 PS activities were observed under the AP condition than under the PP and NP conditions at both speeds. Significantly higher T2 PS activities were observed under the AP condition than under the PP and NP conditions at fast speed. However, the muscle activities of the VM and GCM did not show significant changes with changes in pelvic posture at both speeds. All muscle activities were significantly higher under the fast speed than under the moderate speed in three pelvic postures. Conclusion: There were significant differences in the changes of pelvic tilting on muscle activities of trunk and lower limb were observed in healthy adults. NP condition can be introduced the most efficienct posture for muscle activities of trunk and lower limb in robo-horseback riding.

수학학습클리닉 프로그램 평가 모형 개발에 관한 연구

김정현,고호경,허난,황혜정,Kim, Jeong Hyun,Ko, Ho Kyoung,Huh, Nan,Hwang, Hye Jeang 한국수학교육학회 2017 수학교육논문집 Vol.31 No.3

수학학습클리닉은 학생과의 지속적인 만남을 통해 고민을 함께 얘기해보면서 수학학습에 대한 정의적인 부분의 변화를 강조하는 내용으로 앞으로 우리 학생들이 수학에 대해 긍정적인 마음으로 수학을 접할 수 있도록 안내하는 프로그램이다. 하지만 일선학교에서 수학학습클리닉은 각 학교에서 교사의 재량에 의해 다양한 형태로 운영이 되고 있어 수학학습클리닉이 제대로 그 목적을 달성하고 있는 지를 확인하기가 어렵다. 이런 문제점을 해결하기 위해 수학학습클리닉 운영을 위해 갖추어야 할 기본적인 사항을 점검하고 운영을 하는 과정에서 필요한 부분을 체크할 수 있는 가이드라인의 역할을 할 수 있는 프로그램 평가모형의 필요성이 절실하다. 이에 본 연구의 목적은 수학학습클리닉 프로그램 평가모형이 학교현장에서 수학학습클리닉이 체계적이고 효율적으로 운영될 수 있도록 수학학습클리닉 운영을 위한 가이드라인이 될 수 있을 것이다. 그 결과 수학학습클리닉의 운영이 보다 체계적이 될 것이며 프로그램 운영을 점검하고 운영의 문제점을 수정 보완하여 진행이 될 것이다. Recently, 'students who gave up mathematics' became social problems. The need for systematic support for spreading and seating mathematics clinics was recognized. The mathematics clinic emphasizes the change of the affective aspects by constantly meeting the students and listening to the worries of the students. It is also a program that guides students in the future to see mathematics in a positive way. However, at school, mathematics clinics are operated in various forms at the discretion of teachers. Therefore, it is difficult to confirm whether the purpose of the mathematics clinic is being achieved properly. It is necessary to prepare a plan that can act as a guideline to check the necessary basic items for the runs of the math clinic and to check the necessary parts in the course of runs The purpose of this study is to develop a model for evaluating mathematics clinic programs which can be a guideline for the operation of mathematics clinic programs in a systematic way and to reduce the confusion of operation of mathematics clinics at the schools. We expect that this evaluation model could provide a direction for the operation of a math clinic.

인간과 하천 6 - 하천과 동화: 강이 죽어가고 있어요

김정현,Kim, Jeong-Hyeon 한국하천협회 2013 하천과 문화 Vol.9 No.4

인간과 하천 4 - 어른도 함께 보는 동화 : 독도와 어린 인어(2)

김정현,Kim, Jeong-Hyeon 한국하천협회 2014 하천과 문화 Vol.10 No.2